26,454 results match your criteria carotid stenosis

In vivo recellularization of xenogeneic vascular grafts decellularized with high hydrostatic pressure method in a porcine carotid arterial interpose model.

PLoS One 2021 22;16(7):e0254160. Epub 2021 Jul 22.

Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Autologous vascular grafts are widely used in revascularization surgeries for small caliber targets. However, the availability of autologous conduits might be limited due to prior surgeries or the quality of vessels. Xenogeneic decellularized vascular grafts from animals can potentially be a substitute of autologous vascular grafts. Read More

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The Diagnostic Accuracy of Intra-Operative Near Infrared Spectroscopy in Carotid Artery Endarterectomy Under Regional Anaesthesia: Systematic Review and Meta-Analysis.

Eur J Vasc Endovasc Surg 2021 Jul 17. Epub 2021 Jul 17.

Department of Angiology and Vascular Surgery, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Surgery and Physiology, Faculdade de Medicina da Universidade do Porto, Porto, Portugal; Department of Biomedicine - Unity of Anatomy, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.

Objective: Intra-operative near infrared spectroscopy (NIRS) is a non-invasive tool used to monitor regional cerebral oxygen saturation during carotid endarterectomy (CEA), for which accuracy remains unclear. Therefore, this systematic review and meta-analysis aimed to determine the diagnostic accuracy of NIRS in patients undergoing CEA under regional anaesthesia (RA).

Data Sources: MEDLINE, Scopus, and Web of Science were searched for studies that compared NIRS with the "awake test" in patients undergoing CEA under RA. Read More

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Symptomatic subclavian steal syndrome: Report of four Moroccan cases and literature review.

Int J Surg Case Rep 2021 Jul 7;85:106173. Epub 2021 Jul 7.

Mohammed V University of Rabat, Morocco; Vascular Surgery Department, Ibn Sina University Hospital, 10104, Souissi, Rabat, Morocco.

Introduction: Subclavian steal syndrome (SSS) is the hemodynamic phenomenon of blood flow reversal in the vertebral artery due to significant stenosis or occlusion of the proximal ipsilateral subclavian artery.

Materials And Methods: Four patients with subclavian steal syndrome were treated in our center. Percutaneous radial approach was used for angioplasty, primary stenting of subclavian artery was performed, surgical techniques in particular carotid-subclavian bypass and carotid-subclavian transposition were used. Read More

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Eagle syndrome causing severe stenosis of the internal carotid artery.

CMAJ 2021 Jul;193(28):E1091

Division of Otolaryngology - Head and Neck Surgery, Department of Surgery (Howlett, Hearn, Bakala), University of British Columbia, Vancouver, BC; Division of Otolaryngology - Head and Neck Surgery (Hearn, Bakala), Kelowna General Hospital, Kelowna, BC.

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The INfoMATAS project: Methods for assessing cerebral autoregulation in stroke.

J Cereb Blood Flow Metab 2021 Jul 19:271678X211029049. Epub 2021 Jul 19.

Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK.

Cerebral autoregulation refers to the physiological mechanism that aims to maintain blood flow to the brain approximately constant when blood pressure changes. Impairment of this protective mechanism has been linked to a number of serious clinical conditions, including carotid stenosis, head trauma, subarachnoid haemorrhage and stroke. While the concept and experimental evidence is well established, methods for the assessment of autoregulation in individual patients remains an open challenge, with no gold-standard having emerged. Read More

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Endovascular treatment of blood blister-like aneurysms of internal carotid artery: Stent-assisted coiling and pipeline flow diversion.

J Clin Neurosci 2021 Aug 21;90:8-13. Epub 2021 May 21.

Neurosurgery Department, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. Electronic address:

Objective: To report the stent-assisted coil embolization and flow diversion treatments of blood-blister-like aneurysms based on the theory of acute dissection of the internal carotid artery.

Patients And Methods: From July 2016 through July 2020, 27 patients presenting with subarachnoid hemorrhage (SAH) due to rupture of internal carotid artery blood blister-like aneurysms were subjected to endovascular treatment with stent-assisted coiling or Pipeline flow diversion. Clinical outcomes were evaluated using modified Rankin Scale score (mRS). Read More

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Symptomatic nonstenotic carotid disease: Evaluation of a proposed classification scheme in a prospective cohort.

J Clin Neurosci 2021 Aug 21;90:21-25. Epub 2021 May 21.

Barrow Neurological Institute, Phoenix, AZ, USA. Electronic address:

Introduction: Unraveling symptomatic nonstenotic carotid disease (SyNC) as a stroke etiology from other cryptogenic stroke may have important implications for defining natural history and for tailoring secondary prevention strategies. We aim to describe the characteristics of the plaques in a prospectively-collected cohort of patients with non-invasive imaging suggesting symptomatic carotid stenosis but whose DSA demonstrated nonstenotic atheromatous disease, and to evaluate the recurrence rate depending on the type of SyNC.

Methods: We reviewed prospectively-collected data for patients presenting with new neurologic events and non-invasive imaging suggestive of moderate or severe (≥50%) carotid stenosis between July 2016 and October 2018. Read More

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Editorial for "Decreasing Spatial Variability of Individual Watershed Areas by Revascularization Therapy in Patients with High-Grade Carotid Artery Stenosis".

Audrey P Fan

J Magn Reson Imaging 2021 Jul 16. Epub 2021 Jul 16.

Department of Neurology, University of California, Davis, California, USA.

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Conventional Carotid Endarterectomy with Shunt versus Eversion Carotid Endarterectomy without Shunt does the Technique Influence the Outcome in Symptomatic Critical Carotid Stenosis.

Asian J Neurosurg 2021 Apr-Jun;16(2):321-325. Epub 2021 May 28.

Department of Cardio Vascular and Thoracic Surgery, Division of Vascular Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.

Introduction: Carotid endarterectomy (CEA) is a surgical procedure done to prevent future embolic stroke in patients with internal carotid artery (ICA) stenosis. Conventional CEA (c-CEA) and eversion CEA (e-CEA) are two surgical techniques used for the above. As carotid shunt is rarely used in e-CEA, a certain amount of cerebral ischemia occurs in patients who were already having carotid stenosis. Read More

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Plaque Elasticity and Intraplaque Neovascularisation on Carotid Artery Ultrasound: A Comparative Histological Study.

Eur J Vasc Endovasc Surg 2021 Jul 12. Epub 2021 Jul 12.

Department of Ultrasound in Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China. Electronic address:

Objective: Plaque elasticity and intraplaque neovascularisation are strongly suggestive of vulnerable plaque. This study aimed to investigate the relationship between intraplaque neovascularisation and plaque elasticity, and to compare the ultrasound findings with histopathological changes.

Methods: Patients enrolled in this study presented with symptomatic carotid stenosis (> 70%) and later underwent both pre-operative ultrasonography and endarterectomy. Read More

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Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association.

Stroke 2021 Jul 15:STR0000000000000382. Epub 2021 Jul 15.

Primary care teams provide the majority of poststroke care. When optimally configured, these teams provide patient-centered care to prevent recurrent stroke, maximize function, prevent late complications, and optimize quality of life. Patient-centered primary care after stroke begins with establishing the foundation for poststroke management while engaging caregivers and family members in support of the patient. Read More

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Neuroprotective action of Cortexin, Cerebrolysin and Actovegin in acute or chronic brain ischemia in rats.

PLoS One 2021 14;16(7):e0254493. Epub 2021 Jul 14.

Volgograd State Medical University (VSMU), Volgograd, Russia.

This study was the first to compare the neuroprotective activity of Cerebrolysin®, Actovegin® and Cortexin® in rodent models of acute and chronic brain ischemia. The neuroprotective action was evaluated in animals with acute (middle cerebral artery occlusion) or chronic (common carotid artery stenosis) brain ischemia models in male rats. Cortexin® (1 or 3 mg/kg/day), Cerebrolysin® (538 or 1614 mg/kg/day) and Actovegin® (200 mg/kg/day) were administered for 10 days. Read More

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Letter to the Editor Regarding a New Technical Principle of Carotid Artery Stenting With Lesion Crossing Using a 0.035-inch Guidewire and 6-4-French Tapering-Type Catheter for Severe Stenosis.

Cardiovasc Intervent Radiol 2021 Jul 13. Epub 2021 Jul 13.

Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minamikoshigaya, Koshigaya-shi, Saitama, 343-8555, Japan.

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Symptomatic migraine: A systematic review to establish a clinically important diagnostic entity.

Headache 2021 Jul 12. Epub 2021 Jul 12.

Danish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Glostrup, Denmark.

Objective: To determine if a clinical presentation indistinguishable from migraine can occur due to an underlying condition or pathology, that is, "symptomatic migraine."

Background: It is currently not clear whether migraine truly can be caused by an underlying condition or pathology. Characterization of the etiology and clinical features of possible symptomatic migraine is of significant clinical importance and further may help elucidate the pathophysiology of migraine. Read More

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Lemierre syndrome leading to an ischaemic stroke and malignant cerebral oedema.

BMJ Case Rep 2021 Jul 12;14(7). Epub 2021 Jul 12.

Neurosurgery, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, Puerto Rico.

Lemierre syndrome is an often misdiagnosed disease caused by an anaerobic bacterial infection that produces thrombophlebitis of the internal jugular vein and septic metastasis to distal organs, especially the lungs. Carotid stenosis or thrombosis is a rare complication. We present a patient with Lemierre syndrome who developed malignant cerebral oedema secondary to an ischaemic stroke which required a decompressive craniectomy. Read More

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[Spontaneous craniocervical dissection].

Radiologe 2021 Jul 12. Epub 2021 Jul 12.

Neurologische Klinik, Knappschaftskliniken Saar, Standort Sulzbach, An der Klinik 10, 66280, Sulzbach Saar, Deutschland.

Spontaneous craniocervical dissection is one of the main causes of stroke in juvenile and middle-aged patients. It is caused by intramural hematoma which may result in stenosis or even occlusion of the artery. Clinical manifestation varies from local pain to ischemic complications. Read More

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Isolation and identification of leukocyte populations in intracranial blood collected during mechanical thrombectomy.

J Cereb Blood Flow Metab 2021 Jul 11:271678X211028496. Epub 2021 Jul 11.

Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA.

Using standard techniques during mechanical thrombectomy, the Blood and Clot Thrombectomy Registry and Collaboration (BACTRAC) protocol (NCT03153683) isolates intracranial arterial blood distal to the thrombus and proximal systemic blood in the carotid artery. We augmented the current protocol to study leukocyte subpopulations both distal and proximal to the thrombus during human stroke (n = 16 patients), and from patients with cerebrovascular disease (CVD) undergoing angiography for unrelated conditions (e.g. Read More

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Commentary: Stenting in High-Grade Internal Carotid Artery Stenosis: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 Jul 9. Epub 2021 Jul 9.

Department of Radiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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Fluorodeoxyglucose uptake in relation to fat fraction and R2* in atherosclerotic plaques, using PET/MRI: a pilot study.

Sci Rep 2021 Jul 9;11(1):14217. Epub 2021 Jul 9.

Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

Inflammation inside Atherosclerotic plaques represents a major pathophysiological process driving plaques towards rupture. Pre-clinical studies suggest a relationship between lipid rich necrotic core, intraplaque hemorrhage and inflammation, not previously explored in patients. Therefore, we designed a pilot study to investigate the feasibility of assessing the relationship between these plaque features in a quantitative manner using PET/MRI. Read More

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Endarterectomy for symptomatic non-stenotic carotids: a systematic review and descriptive analysis.

Stroke Vasc Neurol 2021 Jul 8. Epub 2021 Jul 8.

Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA

Objective: To systematically analyse prior reports of carotid endarterectomy (CEA) performed in cases of ≤50% carotid stenosis in order to understand patient tolerance and potential benefit.

Methods: A systematic review and descriptive analysis was performed in concordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. An English-language search was performed of online databases using librarian-selected search terms. Read More

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The Predictive Role of a Novel Risk Index in Patients Undergoing Carotid Artery Stenting: Systemic Immune-Inflammation Index.

J Stroke Cerebrovasc Dis 2021 Jul 6;30(9):105955. Epub 2021 Jul 6.

Cardiology, Health Sciences University, Kartal Koşuyolu Heart Training and Research Hospital, Istanbul, Turkey.

Background: Inflammatory mechanisms play an important role in both atherosclerosis and stroke. There are several inflammatory peripheral blood count markers associated with carotid artery stenosis degree, symptomatic carotid artery lesions and carotid artery stent restenosis that reported in previous studies. However, the prognostic role of the blood cell counts and their ratios in predicting in-hospital and long-term outcomes in patients undergoing carotid artery stenting (CAS) has not been comprehensively investigated. Read More

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The angiographic presentation of European Moyamoya angiopathy.

J Neurol 2021 Jul 8. Epub 2021 Jul 8.

Department of Neurology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.

Background And Purpose: Little is known about the angiographic presentation of Moyamoya angiopathy (MMA) in non-Asian patients.

Methods: Conventional cerebral angiograms from 155 Caucasian patients diagnosed as MMA were analyzed with respect to extracranial champagne bottle neck sign, Suzuki stages, collateral status, as well as presence of aneurysms and posterior cerebral artery stenosis.

Results: In 84 of 155 angiograms, the extracranial carotid artery was visualized, in 65 of them (77. Read More

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Effects of interventional therapy on AQP4 gene expression and neuron apoptosis in rabbits with ischemic brain injury caused by carotid artery stenosis.

Int J Clin Exp Pathol 2021 15;14(6):786-793. Epub 2021 Jun 15.

Department of Neurosurgery, The Sixth People's Hospital of Nantong Nantong 226011, Jiangsu Province, China.

: To explore the effects of interventional therapy (IT) on Aquaporin-4 (AQP4) gene expression and neuron apoptosis in rabbits with ischemic brain injury caused by carotid artery stenosis, and to further optimize the therapeutic regime of clinical ischemic brain injury (IBI). : 30 New Zealand rabbits were randomly divided into three groups: Sham group (n=10), IBI group (n=10) and IBI+IT group (n=10). A rabbit model of carotid artery stenosis was established to induce IBI. Read More

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Contrast-induced nephropathy in non-cardiac vascular procedures, a narrative review: Part 2.

Curr Vasc Pharmacol 2021 Jul 8. Epub 2021 Jul 8.

Department of Clinical Biochemistry, Royal Free Hospital Campus, University College London Medical School, University College London (UCL), London, United Kingdom.

This is Part 2 of a narrative review summarizing the literature on CIN after non-cardiac vascular diagnostic or therapeutic procedures, focusing on peripheral artery disease (PAD) and renal artery stenosis (RAS). Part 1 discussed CIN in relation to aortic aneurysms and carotid stenosis. We comment on the incidence, biomarkers, risk factors, and consequences of CIN in patients with PAD or RAS, as well as on strategies to prevent CIN. Read More

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Contrast-induced nephropathy in non-cardiac vascular procedures, a narrative review: Part 1.

Curr Vasc Pharmacol 2021 Jul 8. Epub 2021 Jul 8.

Department of Clinical Biochemistry, Royal Free Hospital Campus, University College London Medical School, University College London (UCL), London, United Kingdom.

Contrast-induced nephropathy (CIN) is an important complication of iodinated contrast medium (CM) administration, which is associated with both short- and long-term adverse outcomes (e.g., cardiorenal events, longer hospital stay, and mortality). Read More

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Magnetic Resonance Angiography and Multidetector CT Angiography in the Diagnosis of Takayasu's Arteritis: Assessment of Disease Extent and Correlation with Disease Activity.

Curr Med Imaging 2021 Jul 7. Epub 2021 Jul 7.

Department of General Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences(NEIGRIHMS), Shillong, India.

Background: Takayasu's arteritis (TA) is a large vessel vasculitis with diverse clinical presentations and arterial vascular bed involvement. It is characterized by chronic, nonspecific inflammation of all layers of the vessel wall, which results in stenosis, occlusion, dilatation, or aneurysm formation in the involved blood vessels.

Methods: The study included 36 patients of TA. Read More

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Prevention of Cerebral Lesion in Asymptomatic Carotid and Vertebral Artery Stenosis in Urgent Cardiac Surgery.

Braz J Cardiovasc Surg 2021 Jul 7. Epub 2021 Jul 7.

Neuromotor Rehabilitation Unit; Istituti Clinici Scientifici Maugeri Spa, Ribera (AG), Italy.

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Biosafety and biodegradation studies of AZ31B magnesium alloy carotid artery stent in vitro and in vivo.

J Biomed Mater Res B Appl Biomater 2021 Jul 8. Epub 2021 Jul 8.

Department of Neurology, The PLA General Hospital, Beijing, China.

Biosafety of AZ31B magnesium (Mg) alloy and the effect of its degradation products on tissues, organs, and whole systems are highly needed to be evaluated before clinical application. This study serves a wide variety of safety evaluations of biodegradable AZ31B alloy on nerve cells. As a result of this in vitro study, the maximum aluminum (Al) ion and Mg ion concentrations in the medium were estimated to be 22 μmol/L and 2. Read More

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Correlation Between Calcification Characteristics of Carotid Atherosclerotic Plaque and Plaque Vulnerability.

Ther Clin Risk Manag 2021 1;17:679-690. Epub 2021 Jul 1.

Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.

Purpose: To investigate the relationship between calcification characteristics of carotid atherosclerotic plaque and lipid rich necrotic core (LRNC) and intraplaque hemorrhage (IPH).

Methods: Patients with severe carotid stenosis undergoing carotid endarterectomy (CEA) were selected. Ultrasound and CT angiography (CTA) were performed to evaluate the calcification characteristics of the plaque before the surgery. Read More

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Management of a Mobile Floating Carotid Plaque Responsible for Calcified Cerebral Emboli: A Double Sword of Damocles.

EJVES Vasc Forum 2020 21;47:69-72. Epub 2021 Apr 21.

Department of Vascular Surgery, Henri Mondor University Hospital, Créteil, France.

Introduction: The management of a rare case of calcified cerebral emboli associated with a mobile carotid plaque (MCP) is reported and discussed.

Report: A 76 year old patient presented with sudden weakness of the left lower limb one month ago, which resolved spontaneously. A cerebral magnetic resonance imaging showed recent multiple infarcts in the right middle cerebral artery (MCA) territory. Read More

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