J Hypertens 2021 Aug 2. Epub 2021 Aug 2.
School of Sport and Exercise, University of Gloucestershire, Gloucester Department of Sport, Exercise & Health, University of Winchester, Winchester Department of Emergency Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Department of Exercise Science, Syracuse University, Syracuse, New York Department of Epidemiology, The Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Department of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas, USA.
Background: Aortic arterial stiffness is a strong independent predictor of cardiovascular disease (CVD); however, its dependence on mean arterial pressure (MAP) limits its clinical utility. The aortic-femoral arterial stiffness gradient (af-SG), a novel marker of CVD risk, may be a promising alternative, but its dependence on MAP is not known. The aim of this study was to determine the relationship between MAP and the af-SG in healthy older adults and those with established disease, including hypertension and diabetes. Read More