Search Our Scientific Publications & Authors

Br Dent J 2021 Apr 9;230(7):407-416. Epub 2021 Apr 9.

Colonel Commandant Royal Army Dental Corps, Regimental Headquarters Royal Army Dental Corps, Surrey, UK.

Between 1661 and 1921, Britain witnessed significant changes in the prevalence of dental caries and its treatment. This period saw the formation of the standing British Army and its changing oral health needs. This paper seeks to identify these changes in the Army and its dental needs, and place them in the context of the changing disease prevalence and dental advances of the time. Read More

J Dent 2021 Apr 6:103659. Epub 2021 Apr 6.

Department of Preventative and Restorative Dental Sciences, UCSF School of Dentistry, San Francisco, CA, USA. Electronic address:

Objectives: The study evaluates the efficacy to remineralize artificial and natural dentin lesions through restorative dental procedures that include the Polymer-Induced Liquid Precursor (PILP) method comprising polyaspartic acid (pAsp).

Methods: Novel ionomeric cement compositions based on bioglass 45S5 and pAsp mixtures, as well as conditioning solutions (conditioner) containing 5 mg/ml pAsp, were developed and tested on demineralized dentin blocks (3-4 mm thick) on shallow and deep lesions with the thickness of 150 µm ± 50 and 700 µm ± 50, respectively. In the first treatment group, 20 µl of conditioner was applied to demineralized shallow (n = 3) and deep (n = 3) lesion specimens for 20 s before restoration with glass ionomer cement (RMGIC). Read More

Clin Oral Investig 2021 Apr 9. Epub 2021 Apr 9.

Bauru Dental School and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Alameda Octávio Pinheiro Brisolla 9-75, Bauru, SP, 17012-901, Brazil.

Objective: Fixed orthodontic appliances impair oral hygiene increasing the risk of non-cavitated lesions (NCLs) and tooth decay. The aim of this study was to compare the outcomes of fluoride and xylitol varnishes in preventing NCLs during comprehensive orthodontic treatment.

Materials And Methods: The sample comprised 55 volunteers from 15 to 20 years of age under orthodontic treatment that were randomly divided into three groups: Fluoride Group (FG; n=17), Xylitol Group (XG; n=19), and Placebo Group (PG; n=19). Read More

Clin Oral Investig 2021 Apr 8. Epub 2021 Apr 8.

Department of Paediatric Dentistry, Medical University of Warsaw, Binieckiego St. 6, 02-097, Warsaw, Poland.

Objective: The study aimed to assess the association between parental-reported vitamin D supplementation and caries in a national sample of 3-year-olds in Poland.

Materials And Methods: A total of 1900 children, representing all provinces of Poland, were invited. The questionnaires concerned vitamin D supplementation, socio-demographics, and oral health behaviours. Read More

ACS Appl Polym Mater 2020 Mar 2;2(3):1134-1144. Epub 2020 Jan 2.

University of Kansas (KU), Lawrence, Kansas.

Bacterial adhesion and growth at the composite/adhesive/tooth interface remain the primary cause of dental composite restoration failure. Early colonizers, including , play a critical role in the formation of dental caries by creating an environment that reduces the adhesive's integrity. Subsequently, other bacterial species, biofilm formation, and lactic acid from demineralize the adjoining tooth. Read More

Evid Based Complement Alternat Med 2021 25;2021:6647849. Epub 2021 Mar 25.

Federal University of Ceara, Fortaleza, Ceará, Brazil.

Background: The objective of this study was to evaluate the clinical and microbiological efficacies of () dental varnish in children at high risk of dental caries..

Methods: This is a longitudinal, randomized, controlled clinical trial. Read More

Int J Dent 2021 26;2021:8868308. Epub 2021 Mar 26.

School of Public Health, Arba Minch University, Arba Minch, Ethiopia.

Introduction: A poor oral hygiene is associated with dental caries, gingivitis, periodontal diseases, bad breath, respiratory and cardiovascular diseases, and chronic kidney diseases. Moreover, a poor oral health has psychosocial impacts that diminish a quality of life and restrict activities in school, at work, and home. African regions carry a major burden of oral health problems. Read More

Int J Dent 2021 24;2021:8841297. Epub 2021 Mar 24.

Department of Orthodontics, Dental Faculty, Qazvin University of Medical Sciences, Qazvin, Iran.

Objectives: This study aimed to assess the radiographic position of impacted mandibular third molars (IMTMs) and their association with pathological conditions.

Materials And Methods: The impaction depth, relationship with ramus, and angulation of 1600 IMTMs and their association with 2 molar distal caries and root resorption, pathological conditions, and proximity to the mandibular canal were evaluated on panoramic radiographs. The IMTM position was determined based on the depth of impaction according to the Pell and Gregory classification, relationship with ramus according to the Pell and Gregory classification, and angulation according to the Winter's classification. Read More

Clin Exp Dent Res 2021 Apr 8. Epub 2021 Apr 8.

Nepean Blue Mountains Local Health District Oral Health Services, Nepean Hospital, Kingswood, New South Wales, Australia.

Objectives: The aim of this retrospective study was to evaluate the outcome of preformed metallic crowns (PMC) utilizing the HT in carious primary molars for children treated within public dental clinics across the Sydney region.

Materials And Methods: A retrospective cohort study was designed, whereby two investigators evaluated 113 primary molars treated with HT PMCs involving 71 participants (aged between 5 and 11 years) after a minimum of 6 months post treatment. The mean time elapsed between crown placement (treatment) and the review was 1. Read More

Health Educ Behav 2021 Apr 8:10901981211004149. Epub 2021 Apr 8.

The University of Texas at Austin, TX, USA.

Dental caries is a chronic oral condition that disproportionately affects low-income women. The aim of this research was to investigate relationships between dental nutrition knowledge, socioecological factors, and prevalence of dental caries in low-income women. This quantitative cross-sectional study involved 220 women who were recruited from Central Texas. Read More

Oral Health Prev Dent 2021 Jan;19(1):217-227

Purpose: To develop an evidence-based Clinical Practice Guideline (CPG) on caries management for the Malaysian population using the ADAPTE trans-contextual adaptation framework.

Materials And Methods: A systematic search was conducted to identify all CPGs related to caries management on guideline repository websites and other platforms. The search findings were screened and the quality of the identified guidelines was evaluated using the AGREE II tool. Read More

Anat Sci Educ 2021 Apr 8. Epub 2021 Apr 8.

Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, People's Republic of China.

Dental anatomy is an integrated, core fundamental dental course, which prepares students for all future clinical dental courses. This study aimed to build up an online dental learning platform of micro-computed tomography-based three-dimensional (3D) tooth models with pulp cavity, and to further evaluate its effectiveness for dental anatomy education using a cohort study. First, ninety-six extracted permanent teeth were scanned by micro-computed tomography and the enamel, dentine, and pulp cavity of each was distinguished by different grey-scale intensities using Mimics software. Read More

Rev Esp Salud Publica 2021 Apr 8;95. Epub 2021 Apr 8.

Unidad Docente de Odontología Integrada Infantil. Departamento de Dermatología, Estomatología y Radiología y Medicina Física. Facultad de Medicina-Odontología. Universidad de Murcia. Murcia. España.

Objective: The use of fluoridated toothpastes is considered the most rational method in dental caries control, and it is recommended for all ages people, but for this they must be established at a minimum concentration of 1,000 ppm of total soluble fluoride, in pediatric patients. The objective of the study was to determine the concentration of total and soluble fluoride present in toothpastes marketed in Spain for pediatric use.

Methods: A descriptive and cross-sectional study was carried out throughout 2019, analyzing 11 toothpastes for pediatric use marketed in Murcia, Spain. Read More

Sci Prog 2021 Apr-Jun;104(2):368504211008054

School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China.

Human teeth have become a prominent source of DNA for human forensic identification as their biological structure is highly resistant to extreme conditions. Previous forensic identification was mainly dependent on the pulp and the other hard tissues of intact teeth. However, there is high likelihood that only carious teeth can be available for forensic analysis. Read More

Anesth Prog 2020 Mar;68(1):47-49

Department of Anesthesiology, Nagoya University Hospital, Nagoya, Japan.

Nicolaides-Baraitser syndrome (NCBRS) is a rare congenital genetic disorder characterized by distinctive facial features similar to Treacher Collins syndrome (TCS). We report the first case of successful nasal fiberoptic intubation in a patient with NCBRS with micrognathia and limited mouth opening due to trismus. A 9-year-old girl with NCBRS and dental caries was scheduled to undergo general anesthesia for a dental extraction. Read More

Caries Res 2021 Apr 7:1-9. Epub 2021 Apr 7.

The First Affiliated Hospital of Henan University, Kaifeng, China.

Fluorosis is a defect in the enamel mineral content caused by excessive fluoride intake during amelogenesis; the interaction of various factors in the development and progression of fluorosis has not been defined. Casein kinase 1α (CK1α) is constitutively active in cells and is involved in diverse cellular processes; however, its expression in fluorosis has not been measured. This study aimed to investigate the effects of fluoride on CK1α expression and to assess the regulation of molecular signaling involving fluoride and CK1α during enamel development. Read More

Clin Oral Investig 2021 Apr 7. Epub 2021 Apr 7.

Postgraduate Program in Dentistry, Federal University of Rio Grande do Sul, Ramiro Barcelos, 2492, Santa Cecília, Porto Alegre, RS, Brazil.

Objective: To investigate whether a healthy diet and added sugar mediate the relationship between socioeconomic status and oral health status in adults.

Methods: This is a secondary cross-sectional analysis of adult participants from the 2015-2016 National Health and Nutrition Examination Survey from the United States (n=3367). Structural equation modeling tested direct and indirect pathways from a latent variable for socioeconomic status to oral health via healthy eating (Health Eating Index) and added sugar in a multiple-mediator multiple-outcome model. Read More

J Adhes Dent 2021 Apr;23(2):159-165

Purpose: To evaluate the effect of inclusion of two dimethyl sulfoxide (DMSO) concentrations in simplified etch-and-rinse adhesives on dentin bonding durability after three years of water storage.

Materials And Methods: Forty-two caries-free third molars were divided into six experimental groups (n = 7) according to the following factors: 1) adhesive (Adper Single Bond 2 [SB], 3M Oral Care; Prime&Bond 2.1 [PB], Dentsply Sirona); 2) concentration of DMSO (control group: 0. Read More

J Adhes Dent 2021 Apr;23(2):91-110

Purpose: The goals of this review are (1) to describe the evidence behind the use of ceramics vs composite resin to restore teeth with anterior veneers using a minimally-invasive strategy; and (2) to discuss the choice of materials and techniques for anterior veneer restorations.

Overview: In recent years new adhesive restorative materials and techniques have been introduced in dentistry, including nanofilled composite resins for direct restorations, new ceramic materials that combine esthetics and strength, and polymer/ceramic materials for indirect restorations that are fabricated chairside using CAD/CAM technology, allowing the dentist to design, mill, and cement the restoration in one session. In spite of the novelty and new technology behind the introduction of new materials, the available evidence that backs some of these materials does not justify their use over similar materials or techniques that have been used by dentists for some years. Read More

Int J Dent Hyg 2021 Apr 7. Epub 2021 Apr 7.

CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

Objectives: The aim of this study was to conduct a systematic review in order to assess the impact of early childhood caries (ECC) and its severity on Oral Health Related Quality of Life (OHRQoL).

Materials And Methods: An electronic search was conducted in MEDLINE, EMBASE, Cochrane, SciELO and Lilacs databases. The study eligibility criteria were primary studies published in English, Spanish or Portuguese that assessed OHRQoL in preschool children with dental caries using validated instruments. Read More

Int J Dent 2021 20;2021:5588832. Epub 2021 Mar 20.

Division of Pediatric Dentistry and Biomaterials Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen 40002, Thailand.

Introduction: Nanohydroxyapatite (nano-HA) has been utilized as an alternative agent for dental enamel remineralization. This study compared remineralization potential of nano-HA toothpaste (NHT), functionalized tricalcium phosphate toothpaste (TCPT), and fluoride toothpaste (FT) on carious lesions.

Materials And Methods: Sixty extracted human premolars were prepared for artificial carious lesions with synthetic polymer gel. Read More

Addiction 2021 Apr 6. Epub 2021 Apr 6.

Faculty of Dentistry, University of Otago, Dunedin, New Zealand.

This review outlines the important oral implications of tobacco use. The lining of the mouth (oral mucosa), if exposed to tobacco and its products in a susceptible individual, can develop benign, potentially malignant, and malignant tumours. Treatment and prognosis depend on tumour type, how early it is detected, its size and site in the oral cavity and whether it has spread. Read More

Sci Rep 2021 Apr 5;11(1):7496. Epub 2021 Apr 5.

Department of Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba, SP, CEP 13414-903, Brazil.

This quasi-experimental study sought to investigate if the mechanical control of biofilm (3-times-a-day) modifies the saliva's ability to buffer the oral environment after 20% sucrose rinse (SR) in children with early childhood caries (ECC). Here, SR reduced the saliva's pH in both groups and the mechanical control of biofilm had a greater effect on this parameter after SR in CF children. The mechanical control of biofilm evidenced a higher buffering capacity in CF children before SR, which was not observed after SR. Read More

Mol Oral Microbiol 2021 Apr 5. Epub 2021 Apr 5.

Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.

Trace metals are essential to all domains of life but toxic when found at high concentrations. While the importance of iron in host-pathogen interactions is firmly established, contemporary studies indicate that other trace metals, including manganese and zinc, are also critical to the infectious process. In this study, we sought to identify and characterize the zinc uptake system(s) of S. Read More

Aust Dent J 2021 Apr 5. Epub 2021 Apr 5.

Institutional affiliations, University of Otago Dental School, Department of Oral Rehabilitation, Faculty of Dentistry.

Conservative pulp therapy (CPT) is an alternative treatment option to tooth removal and root canal treatment (RCT) in the management of deep caries, traumatic pulp exposures, and developmental anomalies. Pulp tissue preservation can extend the long-term survival of teeth through relatively simple restorative procedures. This article aims to update clinicians on the current state of research in materials, techniques and outcomes of vital pulp therapies and provide practical guidelines for their implementation into daily practice. Read More

Open Life Sci 2018 Jan 18;13:174-200. Epub 2018 May 18.

Department of Medical and Clinical Biophysics, Faculty of Medicine, University of P. J. Šafárik in Košice, Trieda SNP 1, Košice, 040 11, Slovakia.

This work describes the current state of research on the potential relationship between protein content in human saliva and dental caries, which remains among the most common oral diseases and causes irreversible damage in the oral cavity. An understanding the whole saliva proteome in the oral cavity could serve as a prerequisite to obtaining insight into the etiology of tooth decay at early stages. To date, however, there is no comprehensive evidence showing that salivary proteins could serve as potential indicators for the early diagnosis of the risk factors causing dental caries. Read More

J Oral Biol Craniofac Res 2021 Apr-Jun;11(2):308-312. Epub 2021 Mar 14.

Department of Biochemistry, Saveetha Dental College, Saveetha University, Chennai, India.

Objective: Genotypic diversity and polymorphism of Streptococcus mutans remain as a topic of interest, as this provides a satisfactory explanation for the contrasting caries status in people harboring Sterptococcus mutans. This systematic review aimed to analyze and appraise Genomic diversity of Streptococcus mutans and its relationship in Early Childhood Caries.

Methods: A literature search was conducted until August 2020 using PubMed, Cochrane central, SIGLE using search keywords and MeSH headings include "Early Childhood caries", "Streptococcus mutans" and "Genotypic diversity". Read More

Georgian Med News 2021 Feb(311):163-168

Peoples' Friendship University of Russia, department of Pediatric Dentistry and orthodontics, Moscow, Russia.

The aim of the study was to determine the influence of various drinking liquids on an the dentoalveolar system in rats. The study was carried out on 25 white male rats from the nursery of Krolinfo branch of the Moscow region which were kept in standard vivarium conditions. Age of rats-3-6 months, weight - 150-200 grams. Read More

Children (Basel) 2021 Mar 22;8(3). Epub 2021 Mar 22.

School of Dental Medicine, University of Colorado, Aurora, CO 80045, USA.

The purpose of our study was to explore the association of acculturation and Latino parent behavioral and psychosocial characteristics. A cross-sectional survey was conducted with 197 parent-children triads. Participating parents completed survey questions encompassing oral health knowledge, behaviors and beliefs from a validated oral health instrument. Read More

Materials (Basel) 2021 Mar 30;14(7). Epub 2021 Mar 30.

School of Dentistry and Oral Health, Griffith University, Brisbane 4222, Australia.

Researchers have developed novel nanocomposites that incorporate additional biomaterials with dimethylaminohexadecyl methacrylate (DMAHDM) in order to reduce secondary caries. The aim of this review was to summarize the current literature and assess the synergistic antibacterial and remineralizing effects that may contribute to the prevention of secondary caries. An electronic search was undertaken in MEDLINE using PubMed, Embase, Scopus, Web of Science and Cochrane databases. Read More