44 results match your criteria carboranes good


Ene Reaction of -Carboryne with Alkynes and Alkenes at Room Temperature: Synthesis of -Carboranyl Allenes and Alkenes.

Org Lett 2021 Apr 2;23(8):2971-2975. Epub 2021 Apr 2.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.

-Carboryne undergoes at room temperature an efficient ene reaction with a large variety of alkynes and alkenes possessing an α-CH proton to give a series of -carboranyl allenes and alkenes in good to high isolated yields. This reaction has a broad substrate scope from alkyl and aryl to silyl substituents. This protocol provides a facile synthetic method for accessing cage C-substituted carboranyl allenes and alkenes, which may be utilized as useful starting materials to synthesize multifunctionalized carboranes. Read More

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Palladium-catalyzed selective B(3)-H arylation of o-carboranes with arylboronic acids at room temperature.

Chem Commun (Camb) 2021 Feb 19;57(13):1655-1658. Epub 2021 Jan 19.

Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Hainan Provincial Key Lab of Fine Chem, Hainan Provincial Fine Chemical Engineering Research Center Hainan University, 58 Renmin Road, Haikou 570228, China.

A palladium-catalyzed selective B(3)-H arylation of o-carboranes at room temperature has been developed using readily available arylboronic acids as the aryl source, and the corresponding 3-aryl-o-carboranes were obtained in good to excellent yields. This method provides a powerful synthetic route for constructing polysubstituted o-carborane derivatives. Read More

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February 2021

Determination of acidity constants, ionic mobilities, and hydrodynamic radii of carborane-based inhibitors of carbonic anhydrases by capillary electrophoresis.

Electrophoresis 2021 Apr 21;42(7-8):910-919. Epub 2021 Jan 21.

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague 6, Czechia.

Capillary electrophoresis (CE) has been applied for determination of the thermodynamic acidity constants (pK ) of the sulfamidoalkyl and sulfonamidoalkyl groups, the actual and limiting ionic mobilities and hydrodynamic radii of important compounds, eight carborane-based inhibitors of carbonic anhydrases, which are potential new anticancer drugs. Two types of carboranes were investigated, (i) icosahedral cobalt bis(dicarbollide)(1-) ion with sulfamidoalkyl moieties, and (ii) 7,8-nido-dicarbaundecaborate with sulfonamidoalkyl side chains. First, the mixed acidity constants, pK , of the sulfamidoalkyl and sulfonamidoalkyl groups of the above carboranes and their actual ionic mobilities were determined by nonlinear regression analysis of the pH dependences of their effective electrophoretic mobility measured by capillary electrophoresis in the pH range 8. Read More

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Palladium-catalyzed regioselective synthesis of B(4,5)- or B(4)-substituted o-carboranes containing α,β-unsaturated carbonyls.

Org Biomol Chem 2020 07;18(25):4723-4727

State Key Laboratory of Fluorine & Nitrogen Chemicals, Xi'an Modern Chemistry Research Institute, Xi'an 710065, China.

With the help of a carboxylic acid directing group, Pd-catalyzed regioselective synthesis of B(4,5)- or B(4)-substituted o-carboranes containing α,β-unsaturated carbonyls has been reported. The -COOH, removed during the course of the reaction, is responsible for controlling the regioselectivity. The desired products could be obtained in moderate to good yields. Read More

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Iridium-Catalyzed Regioselective B(3)-Alkenylation/B(3,6)-Dialkenylation of o-Carboranes by Direct B-H Activation.

Chemistry 2020 Jun 20;26(32):7212-7218. Epub 2020 Mar 20.

Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, University of, Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Rd, Shanghai, 200032, P. R. China.

Iridium-catalyzed formal alkyne hydroboration with cage B-H of o-carborane has been achieved, leading to the controlled synthesis of a series of 3,6-[trans-(AlkCH=CH)] -o-carboranes (Alk=alkyl), 3-cis-(ArCH=CH)-o-carboranes (Ar=aryl), and 3-cis-(ArCH=CH)-6-trans-(AlkCH=CH)-o-carboranes in high yields with excellent regio- and very good cis-trans selectivity. The most electron-deficient B(3,6)-H vertices favor oxidative addition on electron-rich metal centers, which is responsible for the regioselectivity. On the other hand, the configuration of the resultant olefinic units is dominated by alkyne substituents. Read More

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A Phthalocyanine-ortho-Carborane Conjugate for Boron Neutron Capture Therapy: Synthesis, Physicochemical Properties, and in vitro Tests.

Chempluschem 2019 04 5;84(4):345-351. Epub 2019 Feb 5.

Department of Chemistry, Istanbul Technical University, 34469, Maslak, Istanbul, Turkey.

Boronated molecular systems can be applied to boron neutron capture therapy (BNCT). Among these systems, carborane-containing phthalocyanines (Pcs) are the most promising BNCT agents. Herein we report the new zinc (II) complex of the hexacationic Pc 6, which has been obtained as iodide salt through quaternization of the neutral precursor with methyl iodide. Read More

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Old Key Opens the Lock in Carborane: The in Situ NHC-Palladium Catalytic System for Selective Arylation of B(3,6)-H Bonds of -Carboranes via B-H Activation.

Org Lett 2019 Nov 5;21(22):9276-9279. Epub 2019 Nov 5.

State Key Laboratory of Environment-friendly Energy Materials & School of Material Science and Engineering , Southwest University of Science and Technology , 59 Qinglong Road , Mianyang , Sichuan 0086-621010 , P.R. China.

An efficient in situ Pd-NHC catalytic system for regioselective arylation of B(3,6)-H bonds of -carborane has been developed for the first time. A series of symmetric and unsymmetric 3,6-diaryl--carboranes anchored with active groups have been synthesized with moderate to good yields under mild conditions. This work offers an efficient protocol for selective activation of B(3,6)-H bonds and has important value in design coupling reactions for selective functionalization of -carboranes. Read More

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November 2019

Rh-Catalyzed Regioselective Dialkylation of Cage B-H bonds in o-Carboranes: Oxidative Heck Reactions via an Enol Isomerization.

Org Lett 2019 Oct 25;21(19):8018-8021. Epub 2019 Sep 25.

State Key Laboratory of Fluorine & Nitrogen Chemicals , Xi'an Modern Chemistry Research Institute , Xi'an 710065 , China.

In the presence of a carboxylic acid directing group, Rh-catalyzed regioselective directed dialkylation of B(4,5)-H bonds in carboranes and oxidative coupling with allylic alcohols is reported. This strategy constructs a series of 4,5-dialkylated -carboranes in good yields with excellent regioselectivity. A possible catalytic cycle is proposed that involves a tandem sequence of Rh-catalyzed cage B-H activation, alkene insertion, selective β-H elimination, enol isomerization, and decarboxylation. Read More

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October 2019

Metalloradicals Supported by a meta-Carborane Ligand.

Angew Chem Int Ed Engl 2019 Jun 7;58(24):8129-8133. Epub 2019 May 7.

State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, 2005 Songhu road, Shanghai, 200433, P. R. China.

In this work, a pincer-type complex [Cp*Ir-(SNPh)(SNHPh)(C B H )] (2) was synthesized and its reactivity studied in detail. Interestingly, molecular hydrogen can induce the transformation between the metalloradical [Cp*Ir-(SNPh) (C B H )] (5 ) and 2. A mixed-valence complex, [(Cp*Ir) -(SNPh) (C B H )] (7 ), was also synthesized by one-electron oxidation. Read More

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Tuning the photophysical properties of carboranyl luminophores by closo- to nido-carborane conversion and application to OFF-ON fluoride sensing.

Dalton Trans 2018 Dec;47(48):17441-17449

Department of Chemistry, University of Ulsan, Ulsan 44610, Republic of Korea.

A family of closo-carborane-appended luminophores (closo-OXD1-2 and closo-DPS1-2) in which 2-R-o-carboranes (R = H, Me) are attached to the diphenyl-1,3,4-oxadiazole (OXD) or diphenyl-sulfone (DPS) acceptor groups were prepared and characterized. Deboronation of the closo-carborane cage produced the corresponding nido-carboranyl luminophores (nido-OXD1-2 and nido-DPS1-2). Whereas the closo-compounds were poorly emissive in THF (ΦPL < 0. Read More

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December 2018

Palladium catalyzed selective arylation of o-carboranes via B(4)-H activation: amide induced regioselectivity reversal.

Chem Commun (Camb) 2018 Dec 19;54(96):13603-13606. Epub 2018 Nov 19.

State Key Laboratory of Environment-friendly Energy Materials & School of Material Science and Engineering, Southwest University of Science and Technology, 59 Qinglong Road, Mianyang, Sichuan, P. R. China.

By changing the charge distribution of boron vertices via introducing an amide on cage B(9), the selective B(4) arylation of o-carboranes via Suzuki-Miyaura coupling has been developed. A series of o-carborane derivatives decorated with diverse active groups have been synthesized with moderate to good yields, which have been proved to be further transformed to a novel kind of tri-substituted nido-carborane fused oxazole with potential application in boron neutron capture therapy, organometallic as well as coordination chemistry. Read More

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December 2018

Palladium-Catalyzed Selective Five-Fold Cascade Arylation of the 12-Vertex Monocarborane Anion by B-H Activation.

J Am Chem Soc 2018 Oct 1;140(42):13798-13807. Epub 2018 Oct 1.

Department of Chemistry , Zhejiang University , 38 Zheda Road , 310027 Hangzhou , People's Republic of China.

A series of cage penta-arylated carboranes have been synthesized by palladium-catalyzed intermolecular coupling of the C-carboxylic acid of the monocarba- closo-dodecaborate anion [CBH] with iodoarenes by direct cage B-H bond functionalization. These transformations set a record in terms of one-pot directing group-mediated activation of inert bonds in a single molecule. The methodology is characterized by high yields, good functional group tolerance, and complete cage regioselectivity. Read More

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October 2018

High T and Thermo-Oxidatively Stable Thermosetting Polyimides Derived from a Carborane-Containing Diamine.

Macromol Rapid Commun 2018 Nov 10;39(21):e1800484. Epub 2018 Sep 10.

School of Materials Science and Engineering, Beihang University, Beijing, 100191, China.

To provide high-temperature polyimide matrix resins, novel carborane-containing thermosetting polyimides are presented. First, the low-viscosity carborane-containing imide oligomers are synthesized using newly designed 1-(3-amino-4-tolyl)-2-(4-aminophenyl)-o-carborane and aromatic dianhydride as monomers, 4-phenylethynyl phthalic anhydride as the end-capping reagent. Followed by thermal curing, the resulting polyimides show high T (≥500 °C) and above 92. Read More

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November 2018

Carborane-BODIPY Dyads: New Photoluminescent Materials through an Efficient Heck Coupling.

Chemistry 2018 Oct 19;24(58):15622-15630. Epub 2018 Sep 19.

Department of Chemistry, University of Turin, Via P. Giuria 7, 10125, Torino, Italy.

A small library of carborane-BODIPY/aza-BODIPY dyads were efficiently synthesized by means of a novel convergent synthetic approach, the key step of which is a Pd-catalyzed Heck coupling reaction. The structural characterization and photoluminescence properties of the newly synthesized dyads were evaluated. The presence of the carborane did not significantly alter the photophysical patterns of the BODIPY or aza-BODIPY in the final fluorophores, but it produced a decrease of the emission fluorescent quantum yields that was in the range from 1. Read More

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October 2018

Carborane-Induced Excimer Emission of Severely Twisted Bis-o-Carboranyl Chrysene.

Angew Chem Int Ed Engl 2018 Aug 12;57(33):10640-10645. Epub 2018 Jul 12.

Department of Chemistry and Centre for Plastic Electronics, Imperial College London, London, SW7 2AZ, UK.

The synthesis of a highly twisted chrysene derivative incorporating two electron deficient o-carboranyl groups is reported. The molecule exhibits a complex, excitation-dependent photoluminescence, including aggregation-induced emission (AIE) with good quantum efficiency and an exceptionally long singlet excited state lifetime. Through a combination of detailed optical studies and theoretical calculations, the excited state species are identified, including an unusual excimer induced by the presence of o-carborane. Read More

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Pd(ii)-catalyzed synthesis of bifunctionalized carboranes cage B-H activation of 1-CHNH--carboranes.

Chem Sci 2018 Apr 27;9(16):3964-3969. Epub 2018 Mar 27.

State Key Laboratory of Coordination Chemistry , School of Chemistry and Chemical Engineering , Nanjing University , Nanjing , Jiangsu 210093 , P. R. China . Email:

Aminoalkyl carboranes are anticipated to be valuable synthons toward the synthesis of bifunctionalized carboranes. However, direct cage boron derivation of these carborane derivatives has not been solved. Herein, the reversible conversion of catalytically infeasible -carboranyl methylamines (1-CHNH--carboranes) into bidentate imines initiates Pd-mediated cage B-H activation. Read More

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Palladium-Catalyzed Selective Mono-/Tetraacetoxylation of o-Carboranes with Acetic Acid via Cross Dehydrogenative Coupling of Cage B-H/O-H Bonds.

Inorg Chem 2018 Mar 19;57(5):2925-2932. Epub 2018 Feb 19.

State Key Laboratory Cultivation Base for Nonmetal Composite and Functional Materials & School of Materials Science and Engineering , Southwest University of Science and Technology , 59 Qinglong Road , Mianyang , 0086-621010 Sichuan , People's Republic of China.

A selective mono-/tetraacetoxylation of o-carboranes with acetic acid via cross dehydrogenative coupling of cage B-H/O-H bonds has been developed, and a series of mono- and tetraacetoxylated o-carboranes have been synthesized with moderate to good yields as well as good selectivity. Mechanistic studies indicate that the acetoxyl originates from acetic acid directly, and a nucleophilic addition of Pd-oxo species and dehydration process is proposed. Read More

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12-Vertex Zwitterionic Bis-phosphonium-nido-carborates through Ring-Opening Reactions of 1,2-Diphosphetanes.

Chemistry 2018 Apr 26;24(23):6208-6216. Epub 2018 Mar 26.

Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Leipzig University, Johannisallee 29, 04103, Leipzig, Germany.

Carborane-substituted 1,2-diphosphetanes (Ia,b) react with elemental lithium in THF with cleavage of the P-P bond to give a deep red solution from which, in the case of Ia, red crystals of a lithiated intermediate, [{1-Li(THF)PtBu-6-PtBu-4,1,6-closo-Li(THF)C B H }{Li(THF) }] ⋅2 THF (2 a), are obtained. The compound is dimeric, C -symmetric and contains six lithium and four phosphorus atoms. Two lithium atoms cap the six-membered C B faces, resulting in two 13-vertex closo-clusters (according to Wade's rules) with docosahedral geometry. Read More

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Synthesis of carborane-fused carbo- and heterocycles via zirconacyclopentane intermediates.

Dalton Trans 2018 Feb;47(7):2453-2459

Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

A variety of carborane-fused carbo- and heterocycles were prepared in good to high isolated yields via the reaction of carborane-fused zirconacyclopentane with a series of substrates such as S, Se, Te, CO, XylNC, MeOOC-CH[double bond, length as m-dash]N, PhPCl, BuSnCl and MeGeCl. However, it was found that the Zr-C bond in the zirconacyclopentane did not show any reactivity towards PhBCl, PhCN and PhCH[double bond, length as m-dash]NPh. This approach represents a promising route to functionalized carboranes that are difficult to access by conventional methods. Read More

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February 2018

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

Bioorg Med Chem Lett 2017 11 30;27(21):4786-4788. Epub 2017 Sep 30.

Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic; Department of Organic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, CZ-12843 Prague 2, Czech Republic. Electronic address:

5-[(p-Carborane-2-yl)ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases. Read More

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November 2017

Selective Catalytic B-H Arylation of o-Carboranyl Aldehydes by a Transient Directing Strategy.

J Am Chem Soc 2017 10 23;139(41):14511-14517. Epub 2017 Aug 23.

State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, Jiangsu 210093, P. R. China.

Carboranyl aldehydes are among the most useful synthons in derivatization of carboranes. However, compared to the utilization of carboranyl carboxylic acids in selective B-H bond functionalizations, the synthetic application of carboranyl aldehydes is limited due to the weakly coordinating nature of the aldehyde group. Herein, the direct arylation of o-carboranyl aldehydes has been developed via Pd-catalyzed cage B-H bond functionalization. Read More

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October 2017

Palladium catalyzed/silver tuned selective mono-/tetra-acetoxylation of o-carboranes via B-H activation.

Chem Commun (Camb) 2016 Sep;52(76):11446-11449

State Key Laboratory Cultivation Base for Nonmetal Composite and Functional Materials & School of Materials Science and Engineering, Southwest University of Science and Technology Mianyang, P. R. China.

A palladium catalyzed/silver tuned selective mono- and tetra-acetoxylation of o-carboranes has been developed, and a series of mono- and tetra-acetoxylated o-carboranes decorated with active groups have been synthesized with moderate to good yields as well as excellent selectivity. A mechanism involving electrophilic palladation and cyclopalladation of the B-H bond was proposed. Read More

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September 2016

Phosphine-catalyzed cage carbon functionalization of o-carborane: facile synthesis of alkenylcarboranes.

Chem Commun (Camb) 2016 Sep 11;52(71):10767-70. Epub 2016 Aug 11.

Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

A phosphine-catalyzed alkenylation reaction of o-carborane with electron-deficient alkynes at the C-H vertex of the o-carborane cage has been developed, which led to the preparation of a series of 1-alkenyl-o-carboranes in moderate to very good yields with excellent regio- and stereoselectivity. This highly efficient and simple method represents the first example of organophosphine catalyzed C-H functionalization of o-carborane. Read More

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September 2016

The substituent effect of 2-R-o-carborane on the photophysical properties of iridium(III) cyclometalates.

Dalton Trans 2016 Apr 29;45(13):5667-75. Epub 2016 Feb 29.

Department of Chemistry and EHSRC, University of Ulsan, Ulsan 44610, Republic of Korea.

A family of heteroleptic iridium(iii) cyclometalates, [4-(2-RCB)ppy]2Ir(acac) (3c-3g; CB = o-carboran-1-yl; ppy = 2-phenylpyridinato-C(2),N; acac = acetylacetonate; R = (i)Pr (3c), (i)Bu (3d), Ph (3e), CF3C6H4 (3f), C6F5 (3g)) with various 2-R substituted o-carboranes at the 4-position in the phenyl ring of the ppy ligand, were prepared. The X-ray crystal structure of all complexes, including 3a (R = H) and 3b (R = Me), showed that while the carboranyl C-C bond distance increases with the increasing steric effect of the 2-R substituent (3a-3d), the bond distance is more likely to be influenced by the electronic effect of the substituent for the 2-aryl substituted complexes (3e-3g). The absorption and emission bands of all complexes were red-shifted with respect to those of the parent (ppy)2Ir(acac) (4). Read More

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Straightforward synthesis of radioiodinated Cc-substituted o-carboranes: towards a versatile platform to enable the in vivo assessment of BNCT drug candidates.

Dalton Trans 2015 Jun;44(21):9915-20

Radiochemistry and Nuclear Imaging Group, CIC biomaGUNE, Paseo Miramón 182, San Sebastián, 20009 Guipuzcoa, Spain.

Due to their high boron content and rich chemistry, dicarba-closo-dodecaboranes (carboranes) are promising building blocks for the development of drug candidates with application in Boron Neutron Capture Therapy. However, the non-invasive determination of their pharmacokinetic properties to predict therapeutic efficacy is still a challenge. Herein, we have reported the unprecedented preparation of mono-[(125)I] iodinated decaborane via a catalyst-assisted isotopic exchange. Read More

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Palladium catalyzed selective mono-arylation of o-carboranes via B-H activation.

Chem Commun (Camb) 2015 Apr;51(33):7257-60

State Key Laboratory Cultivation Base for Nonmetal Composite and Functional Materials & School of Materials Science and Engineering, Southwest University of Science and Technology, Mianyang, P. R. China.

Palladium catalyzed selective mono-arylation of o-carboranes with aryl iodides has been developed, and a series of B(8)/B(9)-Ar-o-carboranes anchored with active groups have been synthesized with moderate to good yield as well as good selectivity. The mechanism involving Pd(II) catalyzed electrophilic B-H activation was also proposed. Read More

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Supercarborane radical anions with 2n + 3 electron counts: a combined experimental and theoretical study.

Inorg Chem 2015 Feb 26;54(4):1965-73. Epub 2015 Jan 26.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong , Shatin, New Territories, Hong Kong, China.

The synthesis, structure, spectroscopic characterization, and density functional theory (DFT) calculations of several 13-vertex carborane radical anions were described. Reactions of 13-vertex closo-carboranes with 1 equiv of finely cut sodium metal in tetrahydrofuran at room temperature afforded the corresponding sodium salts of carborane radical anions as dark-red crystals in very good yield. They represent a rare class of clusters having 2n + 3 framework electrons, which lie between the two well-established and abundant closed 2n + 2 (closo) and open 2n + 4 (nido) skeleton systems. Read More

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February 2015

Long-lived excited states of zwitterionic copper(I) complexes for photoinduced cross-dehydrogenative coupling reactions.

Chemistry 2015 Jan 20;21(3):1184-90. Epub 2014 Nov 20.

Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Key Laboratory of Inorganic-Organic Hybrid Functional Materials Chemistry, Ministry of Education, College of Chemistry, Tianjin Normal University, Tianjin 300387 (China).

Four heteroleptic copper(I) complexes containing phenanthroline and monoanionic nido-carborane-diphosphine ligands have been prepared and structurally characterized by various spectroscopic techniques and X-ray diffraction. These complexes exhibit intense absorptions in the visible range and excited-state lifetimes on the microsecond scale. Their application in visible-light-induced cross-dehydrogenative coupling reactions was investigated. Read More

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January 2015

Regioselective insertion of o-carborynes into the α-C-H bond of tertiary amines: synthesis of α-carboranylated amines.

Angew Chem Int Ed Engl 2014 Nov 27;53(47):12902-6. Epub 2014 Oct 27.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong (China).

o-Carboryne can undergo α-CH bond insertion with tertiary amines, thus affording α-carboranylated amines in very good regioselectivity and isolated yields. In this process, the nucleophilic addition of tertiary amines to the multiple bond of o-carboryne generates a zwitterionic intermediate. An intramolecular proton transfer, followed by a nucleophilic attack leads to the formation of the final product. Read More

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November 2014

High yielding synthesis of carboranes under mild reaction conditions using a homogeneous silver(I) catalyst: direct evidence of a bimetallic intermediate.

Angew Chem Int Ed Engl 2014 May 2;53(20):5156-60. Epub 2014 Apr 2.

Department of Chemistry and Chemical Biology, McMaster University, 1280 Main St W., Hamilton, Ont., L8S 4M1 Canada; Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt).

Methods used to prepare functionalized carboranes generally require heating to high temperatures, and thus limits the range of derivatives which can be prepared directly from alkynes. We show here that by using a homogeneous silver(I) catalyst it is now possible to prepare carboranes in good to excellent yield at temperatures below 40 °C, including at room temperature. The process is general and provides an important new synthetic strategy for the preparation of functionalized boron clusters. Read More

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