14,111 results match your criteria capillary liquid

Core-Shell Microcapsules from Unpurified Legume Flours.

ACS Appl Mater Interfaces 2021 Jul 29. Epub 2021 Jul 29.

Physical Chemistry and Soft Matter, Wageningen University and Research, 6708 WE Wageningen, The Netherlands.

Plant-based ingredients are key building blocks for future sustainable advanced materials. Functionality is typically higher for highly purified plant-based ingredients, but this is at the expense of their sustainability value. Here, a method is introduced for creating a soft functional material, with structural elements ranging from the nanometer to the millimeter scale, directly from legume flours. Read More

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Non-targeted LC-MS and CE-MS for biomarker discovery in bioreactors: Influence of separation, mass spectrometry and data processing tools.

Sci Total Environ 2021 Jul 17;798:149012. Epub 2021 Jul 17.

Department of Chemistry, Aalen University, D-73430 Aalen, Germany. Electronic address:

Liquid separation coupled to mass spectrometry is often used for non-targeted analyses in various fields, such as metabolomics. However, the combination of non-standardized methods, various mass spectrometers (MS) and processing tools for data evaluation affect biomarker discovery potentially. Here, we present a comprehensive study of these factors based on non-targeted liquid chromatography coupled to time-of-flight (TOF) and Orbitrap MS and capillary zone electrophoresis to Orbitrap analyses of the same bioreactor samples, describing the correlation of its gas yield with changing feature signal intensity. Read More

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Ultrasonic Atomization: A Mechanism of Tissue Fractionation.

Proc Meet Acoust 2013 May 6;133(5). Epub 2013 May 6.

Ctr. for Industrial and Medical Ultrasound, Appl. Phys. Lab., Univ. of Washington, Seattle, WA, USA.

High intensity focused ultrasound (HIFU) can be used to atomize liquid by creating a fountain on the surface exposed to air. The mechanism of atomization can be most accurately described by the cavitation-wave hypothesis wherein a combination of capillary waves excited on the liquid surface with cavitation beneath the surface produces a fine spray. Here, we show experimentally that a free tissue surface can also be atomized resulting in erosion of tissue from the surface. Read More

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Improvement of sludge dewaterability and disintegration efficiency using electrolytic zero-valent iron activated peroxymonosulfate.

Water Sci Technol 2021 Jul;84(2):458-468

School of Urban Construction, Wuhan University of Science and Technology, 10 of Huangjiahu West Road, Hongshan District, Wuhan 430065, Hubei, P.R. China.

Electrolysis zero-valent iron activated peroxymonosulfate (EZVI-PMS) was applied to enhance sludge dewaterability and disintegration performance. Sludge dewaterability was characterized by capillary suction time (CST), specific resistance to filtration (SRF), and disintegration performance was explored by measuring sludge DNA content, ammonia nitrogen, chemical oxygen demand (COD), extracellular polymeric substances (EPS) and dissolved organic carbon (DOC). EPS, including soluble EPS (SB-EPS), loosely bound EPS (LB-EPS), and tightly bound EPS (TB-EPS) were analyzed by three dimensional fluorescence excitation-emission spectrum (3D-EEM) to confirm the proteins' transformation tendency. Read More

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Sub-100-micron calcium-alginate microspheres: Preparation by nitrogen flow focusing, dependence of spherical shape on gas streams and a drug carrier using acetaminophen as a model drug.

Carbohydr Polym 2021 Oct 29;269:118262. Epub 2021 May 29.

Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan; Department of Mechanical Engineering, National Chiao Tung University, Hsinchu, Taiwan. Electronic address:

We developed a miniature gas-liquid coaxial flow device using glass capillaries, aiming to produce sub-100-μm Ca-alginate microspheres. Depending on collecting distance and the flow rates of nitrogen gas and alginate solution, however, Ca-alginate microparticles of different shapes were obtained. Spherical, monodisperse microparticles (microspheres) could only be obtained at certain gas flow rates and within a corresponding range of collecting distance. Read More

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October 2021

A Novel α-Globin Chain Variant, Hb Nanchang [: c.46G>A, Codon 15 (GT>GT) (Gly→Ser)], Detected by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.

Hemoglobin 2021 Jul 26:1-4. Epub 2021 Jul 26.

Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, People's Republic of China.

Here we report a new α chain variant accidentally discovered during Hb A measurement by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) that revealed the presence of a variant α chain with a mass of 15155 Da. However, this hemoglobin (Hb) variant cannot be detected by the first-line methods such as cation exchange high performance liquid chromatography (HPLC) and capillary electrophoresis (CE). Sanger sequencing confirmed the presence of a heterozygous missense mutation [: c. Read More

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Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula.

Development 2021 Sep 29;148(18). Epub 2021 Mar 29.

Department of Cell and Systems Biology, University of Toronto, Toronto M5S 3G5, Canada.

During Xenopus gastrulation, leading edge mesendoderm (LEM) advances animally as a wedge-shaped cell mass over the vegetally moving blastocoel roof (BCR). We show that close contact across the BCR-LEM interface correlates with attenuated net advance of the LEM, which is pulled forward by tip cells while the remaining LEM frequently separates from the BCR. Nevertheless, lamellipodia persist on the detached LEM surface. Read More

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September 2021

Hemoglobin Fukuoka caused unexpected hemoglobin A results: A case report.

World J Clin Cases 2021 Jul;9(20):5568-5574

Department of Clinical Medical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, Guangdong Province, China.

Background: Glycated hemoglobin (Hb) (HbA) is an indicator that is used to diagnose and monitor the treatment of diabetes. Many factors can affect the detection of HbA. One of the most important of these factors is the Hb variant. Read More

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Co-Immobilized Capillary Enzyme Reactor Based on Beta-Secretase1 and Acetylcholinesterase: A Model for Dual-Ligand Screening.

Front Chem 2021 8;9:708374. Epub 2021 Jul 8.

Departamento de Química, Grupo de Cromatografia de Bioafinidade e Produtos Naturais, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.

We have developed a dual enzymatic system assay involving liquid chromatography-mass spectrometry (LC-MS) to screen AChE and BACE1 ligands. A fused silica capillary (30 cm × 0.1 mm i. Read More

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Recent Applications of Capillary Electrophoresis in the Determination of Active Compounds in Medicinal Plants and Pharmaceutical Formulations.

Molecules 2021 Jul 7;26(14). Epub 2021 Jul 7.

Department of Otolaryngology and Oncology, Faculty of Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej Curie 9 Street, PL-85094 Bydgoszcz, Poland.

The present review summarizes scientific reports from between 2010 and 2019 on the use of capillary electrophoresis to quantify active constituents (i.e., phenolic compounds, coumarins, protoberberines, curcuminoids, iridoid glycosides, alkaloids, triterpene acids) in medicinal plants and herbal formulations. Read More

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Development of magnetism-assisted in-tube solid phase microextraction of phenolic acids in fruit juices prior to HPLC quantification.

J Sep Sci 2021 Jul 20. Epub 2021 Jul 20.

Fujian Key Laboratory of Coastal Pollution Prevention and Control, College of the Environment and Ecology, Xiamen University, Xiamen, 361005, P. R. China.

Magnetism-assisted in-tube solid phase microextraction based on porous monolith mingled with Fe O nanoparticles was developed for capture of phenolic acids in fruit juices. First, poly (1-allyl-3-methylimidazolium bis [(trifluoro methyl) sulfonyl] imide-co-ethylene dimethacrylate) monolith embedded with Fe O nanoparticles was facile fabrication in a capillary and employed as microextraction column. Subsequently, a magnetic coil adopted to produce variable magnetic fields during extraction stage was twined on the microextraction column. Read More

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Delayed Lubricant Depletion of Slippery Liquid Infused Porous Surfaces Using Precision Nanostructures.

Langmuir 2021 Jul 21. Epub 2021 Jul 21.

Photonic Innovations Lab, Department of Electronic & Electrical Engineering, University College London, Torrington Place, London WC1E 7JE, U.K.

Slippery liquid infused porous surfaces (SLIPS) are an important class of repellent materials, comprising micro/nanotextures infused with a lubricating liquid. Unlike superhydrophobic surfaces, SLIPS do not rely on a stable air-liquid interface and thus can better manage low surface tension fluids, are less susceptible to damage under physical stress, and are able to self-heal. However, these collective properties are only efficient as long as the lubricant remains infused, which has proved challenging. Read More

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Enhanced Flow Boiling in Microchannels Integrated with Hierarchical Structures of Micro-Pinfin Fences and Nanowires.

Langmuir 2021 Jul 19. Epub 2021 Jul 19.

Department of Mechanical Engineering, University of South Carolina, Columbia, South Carolina 29208, United States.

Two-phase flows in microchannels have been extensively investigated due to their wide range of applications including the fluid process and thermal management in electronic devices. In this study, silicon nanowires (SiNWs) were directly integrated with all the inner microchannel surfaces including walls and micro-pinfins (μ-pinfin) to form SiNW-pinfin hierarchical structures. The objective of this study is to explore if the SiNW-decorated surfaces can further enhance flow boiling through promoting local capillary flows with a better managed pressure drop. Read More

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Anomalous Temperature-Controlled Concave-Convex Switching of Curved Oil-Water Menisci.

J Phys Chem Lett 2021 Jul 19;12(29):6834-6839. Epub 2021 Jul 19.

Physics Department & Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 5290002, Israel.

While the curvature of the classical liquid surfaces exhibits only a weak temperature dependence, we demonstrate here a reversible temperature-tunable concave-convex shape switching in capillary-contained, surfactant-decorated, oil-water interfaces. The observed switching gives rise to a concave-convex shape transition, which takes place as a function of the width of the containing capillary. This apparent violation of Young's equation results from a hitherto-unreported sharp reversible hydrophobic-hydrophilic transition of the glass capillary walls. Read More

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Hygro-responsive, Photo-decomposed Superoleophobic/Superhydrophilic Coating for On-Demand Oil-Water Separation.

ACS Appl Mater Interfaces 2021 Jul 19;13(29):35142-35152. Epub 2021 Jul 19.

Key Laboratory of Micro-Systems and Micro-Structures Manufacturing, Ministry of Education and School of Mechatronics Engineering, Harbin Institute of Technology (HIT), Xidazhi 92, Harbin 150001, P. R. China.

The superoleophobic/superhydrophilic material has attracted considerable interest due to the incomparable property of it for the oil-water separation. However, it is a challenge to make the prepared surface superoleophobic and superhydrophilic at the same time since the oleophobic surface tends to repel water. Herein, a hygro-responsive superoleophobic/superhydrophilic coating was fabricated by liquid-phase deposition of TiO with perfluorooctanoic acid. Read More

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Capillary Ionization and Jumps of Capacitive Energy Stored in Mesopores.

J Phys Chem C Nanomater Interfaces 2021 May 30;125(19):10243-10249. Epub 2021 Apr 30.

Institute of Physical Chemistry, Polish Academy of Sciences, 44/52, 01-224 Warsaw, Poland.

We study ionic liquid-solvent mixtures in slit-shaped nanopores wider than a few ion diameters. Using a continuum theory and generic thermodynamic reasoning, we reveal that such systems can undergo a capillary ionization transition. At this transition, the pores spontaneously ionize or deionize upon infinitesimal changes of temperature, slit width, or voltage. Read More

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Unsaturated hemiwicking dynamics on surfaces with irregular roughness.

J Colloid Interface Sci 2021 Jul 5;604:104-112. Epub 2021 Jul 5.

U.S. Army Combat Capabilities Development Command Chemical Biological Center, 8198 Blackhawk Road, Aberdeen Proving Ground, MD 21010-5424, United States.

Hypothesis: Spreading of wetting liquids on rough surfaces can occur in a regime termed hemiwicking in which liquid advances ahead of the bulk liquid droplet front under the influence of capillary forces induced by the surface topography. When the surface topography is periodic as in the case for micropillar arrays, the wetting front is sharp and models describing the wetting dynamics can be derived directly from the periodic geometry. For materials with a highly irregular surface topography, the wetting front is diffuse and deriving analytical spreading model parameters directly from the surface topography is not generally possible. Read More

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Long-term intake of Lactobacillus paracasei KW3110 prevents age-related circadian locomotor activity and changes in gut metabolism in physiologically aged mice.

Exp Gerontol 2021 Jul 13;153:111477. Epub 2021 Jul 13.

Department of Inflammation and Immunosenescence, Geroscience Research Center, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.; Department of Aging Research, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan. Electronic address:

Aging involves age-progressive loss of physiological functions in organs and tissues. We previously showed that Lactobacillus paracasei KW3110 suppressed age-related inflammation and prevented age-related retinal ganglion cell (RGC) loss. As RGCs mediate biological behaviors associated with responses to ambient light, we assessed whether L. Read More

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ISFrag: De Novo Recognition of In-Source Fragments for Liquid Chromatography-Mass Spectrometry Data.

Anal Chem 2021 Jul 16;93(29):10243-10250. Epub 2021 Jul 16.

Department of Chemistry, Faculty of Science, University of British Columbia, 2036 Main Mall, Vancouver, V6T 1Z1 British Columbia Canada.

In-source fragmentation (ISF) is a naturally occurring phenomenon during electrospray ionization (ESI) in liquid chromatography-mass spectrometry (LC-MS) analysis. ISF leads to false metabolite annotation in untargeted metabolomics, prompting misinterpretation of the underlying biological mechanisms. Conventional metabolomic data cleaning mainly focuses on the annotation of adducts and isotopes, and the recognition of ISF features is mainly based on common neutral losses and the LC coelution pattern. Read More

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Surface-confined guanidinium ionic liquid as a new type of stationary phase for hydrophilic interaction liquid chromatography.

J Sep Sci 2021 Jul 16. Epub 2021 Jul 16.

State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, 116023, China.

Guanidinium-based ionic liquids possess lower toxicity and greater designability than commonly used species and have presented good performances in liquid-phase extraction and stationary phase for capillary GC. In the present work, a novel type of surface-confined guanidinium ionic liquid stationary phase was developed by bonding a hexaalkylguanidinium ionic liquid N,N,N',N'-tetramethyl-N",N"-diallylguanidinium bromide onto the surface of 3-mercaptopropyl modified silica. The obtained surface-confined guanidinium ionic liquid silica materials were characterized by elemental analysis, infrared spectrum, and thermogravimetric analysis, and then packed as a HPLC column for the evaluation of chromatographic retention behavior. Read More

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Dynamic mechanical interaction between injection liquid and human tissue simulant induced by needle-free injection of a highly focused microjet.

Sci Rep 2021 Jul 15;11(1):14544. Epub 2021 Jul 15.

Department of Mechanical Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Japan.

This study investigated the fluid-tissue interaction of needle-free injection by evaluating the dynamics of the cavity induced in body-tissue simulant and the resulting unsteady mechanical stress field. Temporal evolution of cavity shape, stress intensity field, and stress vector field during the injection of a conventional injection needle, a proposed highly focused microjet (tip diameter much smaller than capillary nozzle), and a typical non-focused microjet in gelatin were measured using a state-of-the-art high-speed polarization camera, at a frame rate up to 25,000 f.p. Read More

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Supercontinuum generation in a carbon disulfide core microstructured optical fiber.

Opt Express 2021 Jun;29(13):19891-19902

We demonstrate supercontinuum generation in a liquid-core microstructured optical fiber using carbon disulfide as the core material. The fiber provides a specific dispersion landscape with a zero-dispersion wavelength approaching the telecommunication domain where the corresponding capillary-type counterpart shows unsuitable dispersion properties for soliton fission. The experiments were conducted using two pump lasers with different pulse duration (30 fs and 90 fs) giving rise to different non-instantaneous contributions of carbon disulfide in each case. Read More

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Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS.

J Pharm Biomed Anal 2021 Jul 7;204:114251. Epub 2021 Jul 7.

CMC Analytical, GlaxoSmithKline, 1250 S. Collegeville Road, UP 1400, Collegeville, PA, 19426, USA.

The identification and control of monoclonal antibody (mAb) critical quality attributes (CQAs) is a key component of quality by design (QbD). In this work, rapid peptide mapping and native intact charge variants analysis have been developed to comprehensively characterize and monitor mAb CQAs using a microfluidic capillary electrophoresis - mass spectrometry (CE-MS) platform. The ultrafast peptide mapping simultaneously analyzed multiple CQAs, including protein primary structure, oxidation, deamidation, succinimide, C-terminal lysine (Lys) clipping, N-terminal cyclization, and glycosylation. Read More

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Petrel Probe: An Integrated In Situ Sampling and Injection Interface for Fast, High-Efficiency Liquid Chromatography-Mass Spectrometry Analysis.

Anal Chem 2021 Jul 14;93(29):10114-10121. Epub 2021 Jul 14.

Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University, Hangzhou 310058, China.

Herein, we describe an in situ analysis probe, Petrel probe, highly integrating multiple functions of in situ sampling, in situ sample injection, high-performance liquid chromatography (HPLC) separation, and mass spectrometry (MS) electrospray. The Petrel probe was fabricated based on a single capillary, which consists of a micrometer-sized hole for sampling, a packed column for LC separation, and a tapered tip for MS electrospray. The design of the Petrel probe was optimized to obtain higher structural strength, and a polytetrafluoroethylene (PTFE) chip was used for sealing the probe-sampling hole to meet the high-pressure (∼30 MPa) requirement of LC manifold. Read More

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Cylindrical Confinement of Nanocolloidal Cholesteric Liquid Crystal.

J Phys Chem B 2021 Jul 14;125(29):8243-8250. Epub 2021 Jul 14.

Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto, Ontario M5S 3H6, Canada.

The organization of nanocolloidal liquid crystals in constrained geometries has fundamental and practical importance, since under confinement, liquid crystals contain stable topological defects that can serve as templates for nanoparticle organization. Three-dimensional confinement of cholesteric (Ch) liquid crystals formed by cellulose nanocrystals (CNCs) have been extensively studied; however, their two-dimensional confinement remains under-investigated. Here, we report the results of systematic experimental studies of two-dimensional confinement of Ch-CNC liquid crystal in cylindrical capillaries with varying inner diameters. Read More

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Enhanced water uptake in the longitudinal direction by shiitake mycelium in shiitake cultivation logs: increase in effective diffusion coefficient based on mass of liquid water uptake.

Wood Sci Technol 2021 Jul 9:1-31. Epub 2021 Jul 9.

Ishikawa Agriculture and Forestry Research Center, 1-1 Mizuho, Noto-chou, Housu-gun, Ishikawa 927-0311 Japan.

In the cultivation of shiitake mushrooms (), the farmer needs to know the time needed to water in order to adjust the water content of the logs. In this study, six test logs (, diameter of 38-48 mm, length of 110-118 mm) were used, of which some were dried, some had shiitake mycelia grown on them, and some had mold generated on them. Liquid water was supplied to the test logs by placing the longitudinal direction of the test logs along the line of gravity and immersing the bottom of the test logs in water. Read More

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Rapid chiral discrimination of oncometabolite dl-2-hydroxyglutaric acid using derivatization and field asymmetric waveform ion mobility spectrometry/mass spectrometry.

J Sep Sci 2021 Jul 13. Epub 2021 Jul 13.

Laboratory of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

2-Hydroxyglutaric acid is a chiral metabolite whose enantiomers specifically accumulate in different diseases. An enantiomeric excess of the d-form in biological specimens reflects the existence of various pathogenic mutations in cancer patients, however, conventional methods using gas or liquid chromatography and capillary electrophoresis had not been used for large clinical studies because they require multiple analytical instruments and a long run time to separate the enantiomers. Here, we present a rapid separation method for dl-2-hydroxyglutaric acid using a chiral derivatizing reagent and field asymmetric waveform ion mobility spectrometry/mass spectrometry, which requires a single analytical instrument and <1 s for the separation. Read More

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Relaxation of Thermal Capillary Waves for Nanoscale Liquid Films on Anisotropic-Slip Substrates.

Langmuir 2021 Jul 12;37(29):8667-8676. Epub 2021 Jul 12.

Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom.

The relaxation dynamics of thermal capillary waves for nanoscale liquid films on anisotropic-slip substrates are investigated using both molecular dynamics (MD) simulations and a Langevin model. The anisotropy of slip on substrates is achieved using a specific lattice plane of a face-centered cubic lattice. This surface's anisotropy breaks the simple scalar proportionality between slip velocity and wall shear stress and requires the introduction of a slip-coefficient tensor. Read More

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A Robust Recovery of Ni From Laterite Ore Promoted by Sodium Thiosulfate Through Hydrogen-Thermal Reduction.

Front Chem 2021 25;9:704012. Epub 2021 Jun 25.

College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, China.

Laterite ore is one of the important sources of nickel (Ni). However, it is difficult to liberate Ni from ore structure during reduction roasting. This paper provided an effective way for a robust recovery of Ni from laterite ore by H reduction using sodium thiosulfate (NaSO) as a promoter. Read More

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Large amplitude capillary-gravity solitary waves in a stratified fluid sandwiched between two deep homogeneous layers.

Oleg G Derzho

Chaos 2021 Jun;31(6):063104

Institute of Thermophysics, Avenue Lavrentyev 1, 630090 Novosibirsk, Russia.

The study addresses the propagation of plane capillary gravity solitary waves of permanent form in a three layer formulation. The intermediate fluid is assumed to be stratified, while the upper and lower ones are homogeneous and infinitely deep. One or both interfaces separating these layers are subject to capillarity. Read More

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