33,273 results match your criteria cancer survivors

Cardiovascular disease risks in younger versus older adult B-cell non-Hodgkin's lymphoma survivors.

Cancer Med 2021 May 12. Epub 2021 May 12.

Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

Introduction: Young cancer survivors may be at increased risk of early-onset chronic health conditions. The aim of this population-based study is to estimate cardiovascular disease (CVD) risk among younger versus older B-cell non-Hodgkin's lymphoma (B-NHL) survivors compared with their respective general population cohorts.

Methods: B-NHL survivors diagnosed from 1997 to 2015 in the Utah Cancer Registry were matched with up to five cancer-free individuals on birth year, sex, and birth state, using the statewide Utah Population Database. Read More

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Impact of home-based aerobic training combined with food orientation on food consumption, daily physical activity and cardiorespiratory fitness among breast cancer survivors: six-month clinical trial.

Sao Paulo Med J 2021 May 10. Epub 2021 May 10.

PhD. Physical Education Professional, Postdoctoral Researcher and Adjunct Professor, Postgraduate Program on Movement Sciences and Postgraduate Program on Physiotherapy, Universidade Estadual Paulista (UNESP), Presidente Prudente (SP), Brazil.

Background: Anticancer treatment gives rise to adverse effects such as increased pain and changes to body weight and menstrual cycles, with negative effects on activities of daily living.

Objective: To analyze the effect of food orientation combined with supervised (face-to-face, FF) versus home-based (HB) aerobic training on lifestyle (food consumption and daily physical activity (PA) levels), body composition, metabolic profile and cardiorespiratory fitness, among breast cancer survivors.

Design And Setting: Clinical trial study (six months) conducted at a public university in Presidente Prudente, Brazil. Read More

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Cardiovascular medication and long-term outcome among intensive care unit survivors: a retrospective study.

Ann Palliat Med 2021 Apr 27. Epub 2021 Apr 27.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: We aimed to investigate the association between cardiovascular medications prescribed at ICU discharge and 1-year mortality in intensive care unit (ICU) survivors.

Methods: This retrospective observational study was conducted at a single tertiary academic hospital. The study population comprised adult patients (aged ≥18 years) who were admitted to the general ICU between January 2012 and December 2016, survived, and were discharged. Read More

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The association of stressful life events on weight loss efforts among African American breast cancer survivors.

J Cancer Surviv 2021 May 12. Epub 2021 May 12.

Cancer Center and Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Objective: This study examined whether stressful life events were associated with weight loss, central adiposity, and health behavior changes of African American breast cancer survivors (AABCS) participating in a weight loss intervention.

Methods: We conducted a secondary-data analyses of Moving Forward, a weight loss efficacy trial for AABCS conducted in 2011-2014. Two-hundred forty-six eligible women were randomized to a 6-month interventionist-guided (IG) or self-guided (SG) weight loss intervention. Read More

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Randomized trial of weight loss on circulating ghrelin levels among breast cancer survivors.

NPJ Breast Cancer 2021 May 11;7(1):49. Epub 2021 May 11.

Yale University School of Public Health, New Haven, CT, USA.

Obesity among breast cancer survivors is associated with increased risk for recurrence and mortality. The hormone ghrelin plays a role in initiating appetite and thus regulating body weight. This study aims to determine the effect of a lifestyle intervention on ghrelin levels in breast cancer survivors with a body mass index (BMI) ≥ 25 kg/m. Read More

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CBR3 V244M is associated with LVEF reduction in breast cancer patients treated with doxorubicin.

Cardiooncology 2021 May 11;7(1):17. Epub 2021 May 11.

Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14203, USA.

Background: The CBR3 V244M single nucleotide polymorphism has been linked to the risk of anthracycline-related cardiomyopathy in survivors of childhood cancer. There have been limited prospective studies examining the impact of CBR3 V244M on the risk for anthracycline-related cardiotoxicity in adult cohorts.

Objectives: This study evaluated the presence of associations between CBR3 V244M genotype status and changes in echocardiographic parameters in breast cancer patients undergoing doxorubicin treatment. Read More

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Glioblastoma in adolescents and young adults: An age-based comparative study from Jordan over a 17-year period.

Cancer Epidemiol 2021 May 8;73:101948. Epub 2021 May 8.

Department of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan. Electronic address:

Background: Glioblastoma (GBM) is the most common primary brain tumor. Epidemiologic studies on GBM are rarely reported in the special age group of adolescents and young adults (AYA) in comparison to other age groups. We aim to present data on GBM in Jordan, with a focus on the AYA age, including the incidence, gender, location and outcome, as well as long term survival (LTS). Read More

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Fragmentation of Care Among Black Women With Breast Cancer and Comorbidities: The Role of Health Systems.

JCO Oncol Pract 2021 May;17(5):e637-e644

Rutgers Center for State Health Policy, New Brunswick, NJ.

Purpose: Black women are disproportionately burdened by comorbidities and breast cancer. The complexities of coordinating care for multiple health conditions can lead to adverse consequences. Care coordination may be exacerbated when care is received outside the same health system, defined as care fragmentation. Read More

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Multilevel Influences on Black Cancer Patient Experiences With Care: A Qualitative Analysis.

JCO Oncol Pract 2021 May;17(5):e645-e653

Department of Preventive Medicine, The Gehr Family Center for Health Systems Science, University of Southern California, Los Angeles, CA.

Purpose: Black patients with cancer report worse experiences with health care compared with White patients; however, little is known about what influences these ratings. The objective of this study is to explore the multilevel factors that influence global ratings of care for Black cancer survivors.

Methods: We conducted semistructured in-depth interviews with 18 Black cancer survivors. Read More

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Is substance use among young cancer survivors the result of emotional and physical pain?

Cancer 2021 May 11. Epub 2021 May 11.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.

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Substance use, substance use disorders, and treatment in adolescent and young adult cancer survivors-Results from a national survey.

Cancer 2021 May 11. Epub 2021 May 11.

Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.

Background: Substance use can exacerbate cancer-related morbidity and mortality in adolescent/young adult (AYA) cancer survivors and place them at increased risk for adverse health outcomes. The objective of this study was to assess substance use, misuse, and substance use disorders [SUDs], as well as receipt of treatment for SUDs, among AYA cancer survivors.

Methods: The authors used data from the National Survey of Drug Use and Health (2015-2018) to identify a nationally representative sample of AYAs aged 12 to 34 years. Read More

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Social distancing during the COVID-19 pandemic and health-related quality of life among esophageal cancer survivors.

Acta Oncol 2021 May 11:1-8. Epub 2021 May 11.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

Purpose: The purpose was to investigate whether social distancing during the COVID-19 pandemic reduced health-related quality of life (HRQL) in esophageal cancer patients and if so, to identify factors related to the HRQL changes.

Methods: A prospective Swedish nationwide study of patients who undergone surgery for esophageal cancer between 2013 and 2019. Telephone interviews were conducted 5 weeks and 13 weeks after the introduction of social distancing recommendations. Read More

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Cognitive changes after breast cancer: a scoping review to identify problems encountered by women when returning to work.

Disabil Rehabil 2021 May 11:1-19. Epub 2021 May 11.

Discipline of Occupational, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.

Purpose: A scoping review of international literature was conducted to identify the various problems encountered by women with breast cancer associated with cognitive deficits, and the relationship to work roles and tasks.

Method: This scoping review was conducted using the structure recommended by Arksey & O'Malley in consideration of the PRISMA extension for Scoping Reviews checklist and reviewed for quality, inclusion criteria and key findings related to cognitive changes after breast and impact on work. Searches were conducted in five databases from January 2000 to December 2020. Read More

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Subjective cognition and mood in persistent chemotherapy-related cognitive impairment.

J Cancer Surviv 2021 May 11. Epub 2021 May 11.

Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, 1601 23rd Ave. South, Nashville, TN, 37212, USA.

Purpose: Persistent chemotherapy-related cognitive impairment (CRCI) is commonly reported following cancer treatment and negatively affects quality of life. While past research has focused on potential pathophysiological mechanisms underlying this relationship, the role of psychological factors, such as mood, stress, and anxiety, in the development of persistent CRCI has received less attention. As an additional analysis of data from a trial investigating the effects of transdermal nicotine patches on cognitive performance in patients with persistent CRCI, we examined whether change in mood was associated with changes in subjective and objective cognitive functioning. Read More

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Colorectal Cancer and Return to Work: A Pilot Study of Recruiting Cancer Survivors and Their Employers.

Perm J 2021 May;25

Kaiser Permanente Center for Health Research, Portland, OR.

Introduction: In this study we assessed the feasibility of recruiting colorectal cancer survivors and their employers to participate in research on returning to work after a cancer diagnosis.

Methods: Semistructured qualitative interviews were conducted with 6 survivors and 4 employers to collect feedback on 2 recruitment approaches: 1) an employee/cancer survivor-focused approach whereby researchers obtained employer contact information directly from survivors and 2) an employer-focused approach whereby researchers interviewed employers to identify pathways to recruiting survivor-supervisor dyads. Recordings of all interviews were transcribed and analyzed. Read More

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Interventions to improve physical activity in colorectal survivors: protocol for a systematic review and meta-analysis of randomized controlled trials.

J Adv Nurs 2021 May 10. Epub 2021 May 10.

School of Pharmacy, Department of Pharmaceutical Systems and Policy, West Virginia University, Robert C. Byrd Health Sciences Center [North], Morgantown, WV, USA.

Aim: To examine the effectiveness of physical activity (PA) interventions on changes in PA among colorectal cancer survivors, including an examination of theoretical versus atheoretical-driven approaches, with a special focus on their effectiveness across ethnic and racial minorities.

Design: Systematic review with aggregated data meta-analyses.

Data Sources: Using six databases (Cochrane Central Register of Controlled Trials, PubMed, PsycINFO, CINAHL with full text, Scopus and Web of Science), we will screen for randomized controlled trials written in English from May 1, 1993 up to December 31, 2020. Read More

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Untangling interactivity's effects: The role of cognitive absorption, perceived visual informativeness, and cancer information overload.

Patient Educ Couns 2021 May 13;104(5):1059-1065. Epub 2020 Oct 13.

Department of Health Outcomes and Behavior, Moffit Cancer Center, Tampa, FL, 33612, United States.

Objective: Learning about clinical trials is as stressful and challenging for cancer patients as it is for the clinical staff who provide education to patients. Information aids (IAs) can support both discussions and patients' decision-making, especially when IAs offer interactive features that provide information based on individuals' needs and experiences. However, it is not clear which factors contribute to interactive IAs' effectiveness. Read More

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The Working Memory Network and Its Association with Working Memory Performance in Survivors of non-CNS Childhood Cancer.

Dev Neuropsychol 2021 Apr-Jun;46(3):249-264

Division of Neuropediatrics, Development and Rehabilitation, Children's University Hospital, Inselspital, University of Bern, Bern, Switzerland.

Childhood cancer and its treatment puts survivors at risk of low working memory capacity. Working memory represents a core cognitive function, which is crucial in daily life and academic tasks. The aim of this functional MRI (fMRI) study was to examine the working memory network of survivors of childhood cancer without central nervous system (CNS) involvement and its relation to cognitive performance. Read More

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Emergency department visits among people with cancer: Frequency, symptoms, and characteristics.

J Am Coll Emerg Physicians Open 2021 Jun 1;2(3):e12438. Epub 2021 May 1.

Division of Cancer Prevention and Control National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta Georgia USA.

Objective: People with cancer are increasingly more likely to visit an emergency department for acute care than the general population. They often have long wait times and more exposure to infection and receive treatment from staff less experienced with cancer-related problems. Our objective was to examine emergency department (ED) visits among people with cancer to understand how often and why they seek care. Read More

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Longitudinal proteomic analysis of plasma from patients with severe COVID-19 reveal patient survival-associated signatures, tissue-specific cell death, and cell-cell interactions.

Cell Rep Med 2021 May 3:100287. Epub 2021 May 3.

Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.

Mechanisms underlying severe COVID-19 disease remain poorly understood. We analyze several thousand plasma proteins longitudinally in 306 COVID-19 patients and 78 symptomatic controls, uncovering immune and non-immune proteins linked to COVID-19. Deconvolution of our plasma proteome data using published scRNAseq datasets reveals contributions from circulating immune and tissue cells. Read More

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Immuno-Isolating Dual Poly(ethylene glycol) Capsule Prevents Cancer Cells from Spreading Following Mouse Ovarian Tissue Auto-Transplantation.

Regen Med Front 2019 16;2019(1). Epub 2019 Sep 16.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

For female cancer survivors, premature ovarian insufficiency (POI) is a common complication of anticancer treatments. Ovarian tissue cryopreservation before treatment, followed by auto-transplantation after remission is a promising option to restore fertility and ovarian endocrine function. However, auto-transplantation is associated with the risk of re-introducing malignant cells harbored in the stroma of the ovarian autograft. Read More

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September 2019

Anti-cancer Therapy Leads to Increased Cardiovascular Susceptibility to COVID-19.

Front Cardiovasc Med 2021 23;8:634291. Epub 2021 Apr 23.

Faculty Research Centre for Sport, Exercise and Life Sciences, Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom.

Anti-cancer treatment regimens can lead to both acute- and long-term myocardial injury due to off-target effects. Besides, cancer patients and survivors are severely immunocompromised due to the harsh effect of anti-cancer therapy targeting the bone marrow cells. Cancer patients and survivors can therefore be potentially extremely clinically vulnerable and at risk from infectious diseases. Read More

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Review of management and treatment of peritoneal metastases from gastric cancer origin.

J Gastrointest Oncol 2021 Apr;12(Suppl 1):S20-S29

Department of General and Digestive Surgery, Peritoneal Carcinomatosis Unit, Hospital of Fuenlabrada, Fuenlabrada, Madrid, Spain.

Gastric cancer (GC) is the third cause of cancer-related deaths in the world, with less than 25% survivors at 5 years. These results are largely related to the high incidence of peritoneal metastases (PM) in these patients. Nowadays, the standard treatment for GC with PM is palliative systemic chemotherapy (SCT) with a survival of 6 months. Read More

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Gemcitabine maintenance therapy after gemcitabine and platinum drug chemotherapy for naive stage IIIB/IV squamous cell lung cancer: a phase II study.

Anticancer Drugs 2021 May 6. Epub 2021 May 6.

Department of Respiratory Medicine, Hiroshima Prefectural Hospital Department of Molecular and Internal Medicine, Hiroshima University Department of Respiratory Medicine, Hiroshima City Asa Citizens Hospital Department of Respiratory Medicine, Hiroshima Red Cross and Atomic-bomb Survivors Hospital Department of Respiratory Medicine, Miyoshi Central Hospital Department of Respiratory Medicine, JA Hiroshima General Hospital, Hiroshima, Japan.

Platinum doublet is the standard chemotherapy regimen for unresectable nonsmall-cell lung cancer (NSCLC) without a driver mutation. However, for squamous cell lung cancer, the most effective cytotoxic regimen is not yet established. Combination therapy of gemcitabine with a platinum agent is a highly effective treatment among the platinum doublet regimens and is promising as a treatment for advanced squamous cell lung carcinoma. Read More

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Body image, physical activity and psychological health in older female cancer survivors.

J Geriatr Oncol 2021 May 6. Epub 2021 May 6.

Division of Population Sciences, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States of America. Electronic address:

Objectives: To determine the association of physical activity and body image with psychological health outcomes and whether body image mediates the association of physical activity with psychological health among older female cancer survivors.

Materials And Methods: Data from the Women's Health Initiative (WHI) Life and Longevity after Cancer (LILAC) Study were used. Surveys assessed body image (appearance, attractiveness, scars), moderate-strenuous physical activity (min/week), and psychological health (depression, anxiety, distress). Read More

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Cancer patients' participation and commitment to psychological interventions: a scoping review.

Psychol Health 2021 May 9:1-34. Epub 2021 May 9.

Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.

Objective: Some psychological interventions have been developed to improve cancer patients' and survivors' quality of life, well-being, and health engagement. However, studies are usually focused on effectiveness and less on factors influencing survivors' decision to participate, both subjective (e.g. Read More

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Incidence and risk factors of sexual dysfunction in young breast cancer survivors.

Ann Palliat Med 2021 Apr;10(4):4428-4434

Department of General Surgery, the First Medical Center, Chinese PLA General Hospital, Beijing, China.

Background: Sexual dysfunction is common in postoperative breast cancer patients, which seriously affects the quality of life of the patients, especially young patients. The aim of the present study was to investigate the incidence and risk factors of sexual dysfunction in young breast cancer survivors, so as to provide evidence for further intervention.

Methods: A total of 201 young breast cancer patients who were hospitalized in our department from October 2017 to October 2018 were retrospectively enrolled. Read More

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Both intermuscular fat and LVEF decline promote heart failure symptoms in cancer survivors.

Cardiooncology 2021 May 8;7(1):16. Epub 2021 May 8.

Division of Cardiology, VCU Pauley Heart Center, Virginia Commonwealth University, Box 980036, Richmond, VA, 23298, USA.

Background: Approximately 20% of cancer survivors treated with chemotherapy experience worsening heart failure (HF) symptoms post-cancer treatment. While research has predominantly investigated the role of cardiotoxic treatments, much less attention has focused on other risk factors, such as adiposity. However, emerging data in cancer survivors indicates that adiposity may also impact a variety of cardiovascular outcomes. Read More

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Post-diagnostic reliance on plant-compared with animal-based foods and all-cause mortality in omnivorous long-term colorectal cancer survivors.

Am J Clin Nutr 2021 May 8. Epub 2021 May 8.

Institute of Epidemiology, University Hospital Schleswig-Holstein, University of Kiel, Kiel, Germany.

Background: Plant-rich diets are associated with lower cardiometabolic risks and longer survival in the general population, but their association with mortality in cancer survivors is still unclear.

Objectives: We aimed to examine the associations of 3 postdiagnostic plant-based diet indices with all-cause mortality in omnivorous long-term colorectal cancer (CRC) survivors.

Methods: Diet was assessed with FFQs at a median of 6 years after diagnosis in 1404 CRC survivors (56% male; median age, 69 years) in a Northern German prospective cohort study. Read More

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