29,219 results match your criteria calibration data

Estimating Bleeding Risk in Patients with Cancer-Associated Thrombosis: Evaluation of Existing Risk Scores and Development of a New Risk Score.

Thromb Haemost 2021 Sep 20. Epub 2021 Sep 20.

Department of Acute Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

Background:  Bleeding risk is highly relevant for treatment decisions in cancer-associated thrombosis (CAT). Several risk scores exist, but have never been validated in patients with CAT and are not recommended for practice.

Objectives:  To compare methods of estimating clinically relevant (major and clinically relevant nonmajor) bleeding risk in patients with CAT: (1) existing risk scores for bleeding in venous thromboembolism, (2) pragmatic classification based on cancer type, and (3) new prediction model. Read More

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September 2021

Quantitative accuracy in total-body imaging using the uEXPLORER PET/CT scanner.

Phys Med Biol 2021 Sep 20. Epub 2021 Sep 20.

Department of Radiology, UC Davis Health System, 4860 Y Street, Suite 3100, Sacramento, CA 95817, USA, Sacramento, California, 95817, UNITED STATES.

Absolute quantification of regional tissue concentration of radioactivity in PET is a critical parameter-of-interest across various clinical and research applications and is affected by a complex interplay of factors including scanner calibration, data corrections, and image reconstruction. The emergence of long AFOV PET systems widens the dynamic range accessible to PET and creates new opportunities in reducing scan time and radiation dose, delayed or low radioactivity imaging, as well as kinetic modeling of the entire human. However, these imaging regimes impose challenging conditions for accurate quantification due to constraints from image reconstruction, low count conditions, as well as large and rapidly changing radioactivity distribution across a large AFOV. Read More

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September 2021

Algorithm for Individual Prediction of COVID-19 Hospitalization from Symptoms: Development and Implementation Study.

JMIR Public Health Surveill 2021 Sep 14. Epub 2021 Sep 14.

Epidemiology Unit, Agency for the Protection of Health of the Metropolitan Area of Milan, Via Conca del Naviglio 45, Milan, IT.

Background: The coronavirus disease 2019 (COVID-19) pandemic has generated a huge strain on the health care system worldwide. The metropolitan area of Milan, Italy was one of the most hit area in the world.

Objective: Risk prediction models developed combining administrative data bases and basic clinical data are needed to stratify individual patient risk for public health purposes. Read More

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September 2021

A Comprehensive Study of 3-D Vision-Based Robot Manipulation.

IEEE Trans Cybern 2021 Sep 20;PP. Epub 2021 Sep 20.

Robot manipulation, for example, pick-and-place manipulation, is broadly used for intelligent manufacturing with industrial robots, ocean engineering with underwater robots, service robots, or even healthcare with medical robots. Most traditional robot manipulations adopt 2-D vision systems with plane hypotheses and can only generate 3-DOF (degrees of freedom) pose accordingly. To mimic human intelligence and endow the robot with more flexible working capabilities, 3-D vision-based robot manipulation has been studied. Read More

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September 2021

Development and validation of a nomogram for predicting overall survival in pediatric patients with atypical teratoid/rhabdoid tumors.

Turk Neurosurg 2021 May 3. Epub 2021 May 3.

Lishui Municipal Central Hospital, Department of Orthopedics, Lishui, China.

Aim: The clinical outcomes of patients with atypical teratoid/rhabdoid tumors (ATRTs) are heterogeneous, making it difficult to predict prognosis. This study aimed to construct a reliable prediction model for pediatric ATRT patients.

Material And Methods: Population-based data of patients diagnosed with intracranial ATRT were extracted from the National Cancer Institute\'s Surveillance, Epidemiology, and End Results database. Read More

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Physical density estimations of single- and dual-energy CT using material-based forward projection algorithm: a simulation study.

Br J Radiol 2021 Sep 19:20201236. Epub 2021 Sep 19.

Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, Beihang University, Key Laboratory of Big Data-Based Precision Medicine (Beihang University), Ministry of Industry and Information Technology, Beijing, China.

Objectives: This study aims to evaluate the accuracy of physical density prediction in single-energy CT (SECT) and dual-energy CT (DECT) by adapting a fully simulation-based method using a material-based forward projection algorithm (MBFPA).

Methods: We used biological tissues referenced in ICRU Report 44 and tissue substitutes to prepare three different types of phantoms for calibrating the HU-to-density curves. Sinograms were first virtually generated by the MBFPA with four representative energy spectra ( 80 kVp, 100 kVp, 120 kVp, and 6 MVp) and then reconstructed to form realistic CT images by adding statistical noise. Read More

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September 2021

Predicting outcomes of psychotherapy for depression with electronic health record data.

J Affect Disord Rep 2021 Dec 24;6:100198. Epub 2021 Jul 24.

Kaiser Permanente Washington Health Research Institutes, Seattle, WA, USA.

Predictive analytics with electronic health record (EHR) data holds promise for improving outcomes of psychiatric care. This study evaluated models for predicting outcomes of psychotherapy for depression in a clinical practice setting. EHR data from two large integrated health systems (Kaiser Permanente Colorado and Washington) included 5,554 new psychotherapy episodes with a baseline Patient Health Questionnaire (PHQ-9) score ≥ 10 and a follow-up PHQ-9 14-180 days after treatment initiation. Read More

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December 2021

Validity and Reliability of the Computrainer Lab™ During Simulated 40 and 100 km Time-Trials.

Front Sports Act Living 2021 1;3:735046. Epub 2021 Sep 1.

Department of Kinanthropology, Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC, Canada.

The validity and reliability of the Computrainer Lab (CT) was assessed, for the first time, using a high-precision motor-driven calibration rig during simulated variable intensity 40 and 100 km time-trials (TTs). The load patterns imposed by the CT were designed from previously published studies in trained cyclists and included multiple 1 or 4 km bursts in power output. For the 40 and 100 km TTs, cluster-based analyses revealed a mean measurement error from the true workload of respectively 0. Read More

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September 2021

Novel model combining contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy.

World J Clin Cases 2021 Aug;9(24):7009-7021

Department of Hepatobiliary Surgery, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, Fujian Province, China.

Background: Surgery is the primary curative option in patients with hepatocellular carcinoma (HCC). However, recurrence within 2 years is observed in 30%-50% of patients, being a major cause of mortality.

Aim: To construct and verify a non-invasive prediction model combining contrast-enhanced ultrasound (CEUS) with serology biomarkers to predict the early recurrence of HCC. Read More

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A Radiomics Model for Predicting Early Recurrence in Grade II Gliomas Based on Preoperative Multiparametric Magnetic Resonance Imaging.

Front Oncol 2021 2;11:684996. Epub 2021 Sep 2.

Department of Radiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

Objective: This study aimed to develop a radiomics model to predict early recurrence (<1 year) in grade II glioma after the first resection.

Methods: The pathological, clinical, and magnetic resonance imaging (MRI) data of patients diagnosed with grade II glioma who underwent surgery and had a recurrence between 2017 and 2020 in our hospital were retrospectively analyzed. After a rigorous selection, 64 patients were eligible and enrolled in the study. Read More

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September 2021

Development and Validation of a Novel Model for Predicting Prognosis of Non-PCR Patients After Neoadjuvant Therapy for Breast Cancer.

Front Oncol 2021 1;11:675533. Epub 2021 Sep 1.

Department of Pathology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

Purpose: Pathologic complete response (pCR) after neoadjuvant therapy is an important indicator of long-term prognosis and the primary endpoint of many neoadjuvant studies. For breast cancer patients who do not achieve pCR, prognostic indicators related to prognosis are particularly important. This study is constructing a prediction model with more accurate and reliable prediction results by combining multiple clinicopathological factors, so as to provide a more accurate decision-making basis for subsequent clinical treatment. Read More

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September 2021

Development, Testing, Parameterisation and Calibration of a Human PBPK Model for the Plasticiser, Di-(2-propylheptyl) Phthalate (DPHP) Using in Silico, and Human Biomonitoring Data.

Front Pharmacol 2021 2;12:692442. Epub 2021 Sep 2.

Health and Safety Executive, Buxton, United Kingdom.

A physiologically based pharmacokinetic model for Di-(2-propylheptyl) phthalate (DPHP) was developed to interpret the biokinetics in humans after single oral doses. The model was parameterized with and in silico derived parameters and uncertainty and sensitivity analysis was used during the model development process to assess structure, biological plausibility and behaviour prior to simulation and analysis of human biological monitoring data. To provide possible explanations for some of the counter-intuitive behaviour of the biological monitoring data the model included a simple lymphatic uptake process for DPHP and enterohepatic recirculation (EHR) for DPHP and the mono ester metabolite mono-(2-propylheptyl) phthalate (MPHP). Read More

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September 2021

Cost-benefit analysis of calibration model maintenance strategies for process monitoring.

Anal Chim Acta 2021 Oct 27;1180:338890. Epub 2021 Jul 27.

Radboud University, Institute for Molecules and Materials, P.O. Box 9010, 6500 GL, Nijmegen, the Netherlands. Electronic address:

The long-term prediction performance of spectroscopic calibration models is a critical factor to monitor or control many production processes. Over time, new variations may emerge that deteriorate prediction performance. Therefore, models have to be maintained to retain or improve their prediction performance through time, requiring considerable resources and data. Read More

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October 2021

Prediction of tenderness of chicken by using viscoelasticity based on airflow and optical technique.

J Texture Stud 2021 Sep 18. Epub 2021 Sep 18.

China Agricultural University, College of Engineering, Beijing, China.

Tenderness is an index for evaluating meat quality. A prediction model of tenderness was established based on the chicken deformation, which was determined by a viscoelasticity system combined with airflow and optical technique. Different preprocessing methods were used to pre-process the deformation. Read More

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September 2021

Variable selection in the chemometric treatment of food data: A tutorial review.

Food Chem 2021 Sep 7;370:131072. Epub 2021 Sep 7.

Laboratório de Química Analítica e Quimiometria, Centro de Ciências e Tecnologia, Universidade Estadual da Paraíba, 58429-500 Campina Grande, PB, Brazil.

Food analysis covers aspects of quality and detection of possible frauds to ensure the integrity of the food. The arsenal of analytical instruments available for food analysis is broad and allows the generation of a large volume of information per sample. But this instrumental information may not yet give the desired answer; it must be processed to provide a final answer for decision making. Read More

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September 2021

Validation and Public Health Modelling of Risk Prediction Models for Kidney Cancer using UK Biobank.

BJU Int 2021 Sep 19. Epub 2021 Sep 19.

Department of Public health and Primary Care, University of Cambridge, Cambridge, UK.

Objectives: Early detection of kidney cancer improves survival; however, low prevalence means that population-wide screening based on age alone is inefficient. Stratifying the population, using risk models, could enable an individually tailored screening program. Risk models exist but very few have been externally validated. Read More

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September 2021

Identification of a novel immune-related prognostic signature associated with tumor microenvironment for breast cancer.

Int Immunopharmacol 2021 Sep 15;100:108122. Epub 2021 Sep 15.

Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address:

Background: In the view that immune-related genes play a crucial role in breast cancer progression and long-term patient outcomes, we aimed to identify a novel gene signature based on immune-related genes to improve the prognostic prediction of breast cancer.

Methods: RNA sequencing data and clinical information were obtained from The Cancer Genome Atlas (TCGA). Univariate and multivariate Cox regression analyses were conducted to establish the immune-related prognostic signature (IRPS). Read More

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September 2021

Dental students' perceptions of the long case.

Eur J Dent Educ 2021 Sep 18. Epub 2021 Sep 18.

Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.

Introduction: The long case examination is used to assess clinical competency in dental education. However, the academic literature, much of which is in medical education, highlights concerns regarding the relevancy and authenticity of the long case. To date, dental students' experiences of the long case have been under-researched. Read More

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September 2021

Optimisation of the timing of fertilisation assessment for oocytes cultured in standard incubation: lessons learnt from time-lapse imaging of 78 348 embryos.

Hum Reprod 2021 Sep 18. Epub 2021 Sep 18.

CARE Fertility UK, Nottingham, UK.

Study Question: Using time-lapse data, can the current consensus for the timing of fertilisation assessment of oocytes, cultured in standard incubation, be optimised?

Summary Answer: The optimum time to perform fertilisation assessment for oocytes cultured in standard incubation is 16.5 ± 0.5 h post-insemination (hpi), and the current consensus requires modification in order to minimise the chance of fertilisation being missed. Read More

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September 2021

Predicting mortality in intensive care unit patients infected with Klebsiella pneumoniae: A retrospective cohort study.

J Infect Chemother 2021 Sep 14. Epub 2021 Sep 14.

Department of Family Medicine & Population Health (FAMPOP), University of Antwerp, Antwerp, Belgium; Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

Introduction: Although several models to predict intensive care unit (ICU) mortality are available, their performance decreases in certain subpopulations because specific factors are not included. Moreover, these models often involve complex techniques and are not applicable in low-resource settings. We developed a prediction model and simplified risk score to predict 14-day mortality in ICU patients infected with Klebsiella pneumoniae. Read More

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September 2021

A novel robust PLS regression method inspired from boosting principles: RoBoost-PLSR.

Anal Chim Acta 2021 Sep 7;1179:338823. Epub 2021 Jul 7.

Chem House Research Group, Montpellier, France; CIRAD, UMR SELMET, Montpellier, France; SELMET, Univ Montpellier, CIRAD, INRA, Institut Agro, Montpellier, France.

The calibration of Partial Least Square regression (PLSR) models can be disturbed by outlying samples in the data. In these cases the models can be unstable and their predictive potential can be depreciated. To address this problem, some robust versions of the PLSR Algorithm were proposed. Read More

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September 2021

An interactive eye-tracking system for measuring radiologists' visual fixations in volumetric CT images: Implementation and initial eye-tracking accuracy validation.

Med Phys 2021 Sep 17. Epub 2021 Sep 17.

Department of Radiology.

Purpose: Eye tracking approaches have been used to understand the visual search process in radiology. However, previous eye tracking work in computer tomography (CT) has been limited largely to single cross-sectional images or video playback of the reconstructed volume, which do not accurately reflect radiologists' visual search activities and their interactivity with 3-dimensional image data at a computer workstation (e.g. Read More

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September 2021

A Machine Learning Algorithm to Identify Patients at Risk of Unplanned Subsequent Surgery After Intramedullary Nailing for Tibial Shaft Fractures.


J Orthop Trauma 2021 Oct;35(10):e381-e388

Objectives: In the SPRINT trial, 18% of patients with a tibial shaft fracture (TSF) treated with intramedullary nailing (IMN) had one or more unplanned subsequent surgical procedures. It is clinically relevant for surgeon and patient to anticipate unplanned secondary procedures, other than operations that can be readily expected such as reconstructive procedures for soft tissue defects. Therefore, the objective of this study was to develop a machine learning (ML) prediction model using the SPRINT data that can give individual patients and their care team an estimate of their particular probability of an unplanned second surgery. Read More

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October 2021

Independent External Validation of FRAX and Garvan Fracture Risk Calculators: A Sub-Study of the FRISBEE Cohort.

JBMR Plus 2021 Sep 6;5(9):e10532. Epub 2021 Aug 6.

Department of Endocrinology, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.

Probabilistic models including clinical risk factors with or without bone mineral density (BMD) have been developed to estimate the 5- or 10-year absolute fracture risk. We investigated the performance of the FRAX and Garvan tools in a well-characterized population-based cohort of 3560 postmenopausal, volunteer women, aged 60 to 85 years at baseline, included in the Fracture Risk Brussels Epidemiological Enquiry (FRISBEE) cohort, during 5 years of follow-up. Baseline data were used to calculate the estimated 10-year risk of hip and major osteoporotic fractures (MOFs) for each participant using FRAX (Belgium). Read More

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September 2021

Bioinformatics analysis based on immune-autophagy-related lncRNAs combined with immune infiltration in bladder cancer.

Transl Androl Urol 2021 Aug;10(8):3440-3455

Department of Urology, Maoming People's Hospital, Maoming, China.

Background: To construct a prognostic model based on immune-autophagy-related long noncoding RNA (IArlncRNAs), mainly to predict the overall survival rate (OS) of bladder cancer patients and investigate its possible mechanisms.

Methods: Transcriptome and clinical data were obtained from The Cancer Genome Atlas (TCGA) database. We identified the IArlncRNA by co-expression analysis, differential expression analysis, and Venn analysis. Read More

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A Novel Scoring System for Predicting the Metastases of Posterior Right Recurrent Laryngeal Nerve Lymph Node Involvement in Patients With Papillary Thyroid Carcinoma by Preoperative Ultrasound.

Front Endocrinol (Lausanne) 2021 31;12:738138. Epub 2021 Aug 31.

Department of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objective: Our goal was to investigate the correlation between papillary thyroid carcinoma (PTC) characteristics on ultrasonography and metastases of lymph nodes posterior to the right recurrent laryngeal nerve (LN-prRLN). There is still no good method for clinicians to judge whether a patient needs LN-prRLN resection before surgery, and we also wanted to establish a new scoring system to determine whether patients with papillary thyroid carcinoma require LN-prRLN resection before surgery.

Patients And Methods: There were 482 patients with right or bilateral PTC who underwent thyroid gland resection from December 2015 to December 2017 recruited as study subjects. Read More

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COVID outcome prediction in the emergency department (COPE): using retrospective Dutch hospital data to develop simple and valid models for predicting mortality and need for intensive care unit admission in patients who present at the emergency department with suspected COVID-19.

BMJ Open 2021 09 16;11(9):e051468. Epub 2021 Sep 16.

Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.

Objectives: Develop simple and valid models for predicting mortality and need for intensive care unit (ICU) admission in patients who present at the emergency department (ED) with suspected COVID-19.

Design: Retrospective.

Setting: Secondary care in four large Dutch hospitals. Read More

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September 2021

External Validation of the SYNTAX Score II 2020.

J Am Coll Cardiol 2021 Sep;78(12):1227-1238

Department of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland; NHLI, Imperial College London, London, United Kingdom. Electronic address:

Background: The SYNTAX score II 2020 (SSII-2020) was derived from cross correlation and externally validated in randomized trials to predict death and major adverse cardiac and cerebrovascular events (MACE) following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with 3-vessel disease (3VD) and/or left main coronary artery disease (LMCAD).

Objectives: The authors aimed to investigate the SSII-2020's value in identifying the safest modality of revascularization in a non-randomized setting.

Methods: Five-year mortality and MACE were assessed in 7,362 patients with 3VD and/or LMCAD enrolled in a Japanese PCI/CABG registry. Read More

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September 2021

A nomogram to predict stricture-free survival in patients with ureteral stricture after balloon dilation.

BMC Urol 2021 Sep 16;21(1):129. Epub 2021 Sep 16.

Department of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 West Yanjiang Road, Guangzhou, 510210, China.

Background: Balloon dilation is a commonly used minimally invasive endourological treatment of ureteral stricture, but the postoperative recurrence rate is relatively high. And factors contributing to recurrence after treatment are poorly understood. Herein, we sought to develop a novel clinical nomogram to predict ureteral stricture-free survival in patients suffering from ureter stricture and performed balloon dilation. Read More

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September 2021

Formulation and probabilistic assessment of reversible biodegradation pathway of Diclofenac in groundwater.

Water Res 2021 Jul 31;204:117466. Epub 2021 Jul 31.

Department of Civil and Environmental Engineering (DICA), Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano 20133, Italy.

We present a conceptual and mathematical framework leading to the development of a biodegradation model capable to interpret the observed reversibility of the Pharmaceutical Sodium Diclofenac along its biological degradation pathway in groundwater. Diclofenac occurrence in water bodies poses major concerns due to its persistent (and bioactive) nature and its detection in surface waters and aquifer systems. Despite some evidences of its biodegradability at given reducing conditions, Diclofenac attenuation is often interpreted with models which are too streamlined, thus potentially hampering appropriate quantification of its fate. Read More

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