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Fast-Strain Encoded Cardiac Magnetic Resonance During Vasodilator Perfusion Stress Testing.

Front Cardiovasc Med 2021 17;8:765961. Epub 2021 Nov 17.

Department of Cardiology, Vascular Medicine and Pneumology, Gesundheitszentren Rhein-Neckar (GRN) Hospital Weinheim, Weinheim, Germany.

Cardiac magnetic resonance perfusion imaging during vasodilator stress is an established modality in patients with suspected and known coronary artery disease (CAD). This study aimed to evaluate the performance of fast-Strain-Encoded-MRI (fast-SENC) for the diagnostic classification and risk stratification of patients with ischemic heart disease. Perfusion and fast-SENC cardiac magnetic resonance (CMR) images were retrospectively analyzed in 111 patients who underwent stress CMR. Read More

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November 2021

Associations of Insomnia With Hypertension and Coronary Artery Disease Among Patients With Type 2 Diabetes Mellitus.

Front Cardiovasc Med 2021 19;8:730654. Epub 2021 Nov 19.

National Health Commission (NHC), Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China.

This study aimed to determine whether insomnia is associated with hypertension (HBP) and coronary artery disease (CAD) in a hospital-based sample of patients with type 2 diabetes mellitus (T2DM). Our present study included 354 patients with T2DM. According to the diagnostic criteria of insomnia, the participants were assigned to three groups based on the duration of T2DM and insomnia diagnosis. Read More

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November 2021

Three-dimensional liquid chromatography with parallel second dimensions and quadruple parallel mass spectrometry for adult/infant formula analysis.

J Chromatogr A 2021 Nov 22;1661:462682. Epub 2021 Nov 22.

Charles University, Faculty of Pharmacy, Dept. of Analytical Chemistry, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

Three dimensions of chromatographic separation, using split-flow two-dimensional liquid chromatography (SF-2D-LC) with two parallel second dimensions, LC × 2LC, combined with quadruple parallel mass spectrometry (LC3MS4) is demonstrated for analysis of NIST SRM 1849a adult/infant formula. The first dimension, D, was a conventional non-aqueous reversed-phase (NARP) HPLC separation using two C18 columns in series, followed by detection using an ultraviolet (UV) detector, a fluorescence detector (FLD), with flow then split to a corona charged aerosol detector (CAD), and then dual parallel mass spectrometry (MS), conducted in atmospheric pressure photoionization (APPI) and electrospray ionization (ESI) modes. The first second dimension, D(1), UHPLC was conducted on a 50. Read More

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November 2021

Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Eluting Stents.

J Diabetes Res 2021 23;2021:8636050. Epub 2021 Nov 23.

Department of Internal Medicine, Hypertension and Clinical Oncology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

Background: Cardiovascular disease (CVD) with significant involvement of coronary artery disease (CAD) remains a major cause of death and disability among the diabetic population. Although percutaneous coronary intervention (PCI) continues to evolve, type 2 diabetes mellitus (T2DM) is a well-established marker of poor clinical prognosis after PCI, which is mainly attributed to the rapid progression of atherosclerosis requiring recurrent revascularizations. Hence, the use of bioresorbable materials could provide some solution to this problem. Read More

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November 2021

The feasibility and safety of "one-stop" left atrial appendage closure and percutaneous coronary intervention in atrial fibrillation patients with significant coronary artery disease (PCI-LAAC study).

Am J Cardiovasc Dis 2021 25;11(5):679-687. Epub 2021 Oct 25.

Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College Beijing, China.

Background: The anti-thrombotic strategy for patients with atrial fibrillation (AF) who have undergone percutaneous coronary intervention (PCI) for coronary artery disease (CAD) is a common and difficult challenge. This pilot study aimed to assess the feasibility and safety of "one-stop" left atrial appendage closure (LAAC) combined with PCI as an alternative stroke prophylaxis strategy.

Methods: From March 2017 to October 2019, AF patients with elevated bleeding risk and significant stable CAD requiring PCI were recruited to undergo LAAC as alternative stroke prophylaxis in Fuwai Hospital, Beijing, China. Read More

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October 2021

Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency.

Circulation 2021 Nov 30. Epub 2021 Nov 30.

Molecular Medicine, Columbia University Medical Center, New York, NY.

Background: LNK/SH2B3 inhibits JAK/STAT signaling by hematopoietic cytokine receptors. GWAS have shown association of a common SNP in (R262W, T allele) with neutrophilia, thrombocytosis and coronary artery disease (CAD). We have shown that reduces LNK function and that LNK deficient mice display prominent platelet-neutrophil aggregates, accelerated atherosclerosis and thrombosis. Read More

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November 2021

Fabrication and mechanical properties of biomimetic nacre-like ceramic/polymer composites for chairside CAD/CAM dental restorations.

Dent Mater 2021 Nov 23. Epub 2021 Nov 23.

Biomaterials Engineering Group (bioMEG), Bristol Dental School, University of Bristol, UK. Electronic address:

Objective: To fabricate and characterise a novel chairside CAD/CAM composite dental materials. These composites have a nacre-like anisotropic microstructure, consisting of highly aligned ceramic scaffolds infiltrated with polymer.

Method: Bi-directional freeze casting of alumina ceramic suspension was used to fabricate highly aligned ceramic scaffolds that were subsequently uniaxially pressed to control the ceramic volume fraction and then infiltrated with UDMA/TEGDMA polymer. Read More

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November 2021

Preoperative Predictors of Adverse Clinical Outcome in Emergent Repair of Acute Type A Aortic Dissection in 15 Year Follow Up.

J Clin Med 2021 Nov 18;10(22). Epub 2021 Nov 18.

Department of Cardiovascular Surgery, University Medical Center Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3, 24105 Kiel, Germany.

Background: Acute type A aortic dissection (AAAD) has high mortality. Improvements in surgical technique have lowered mortality but postoperative functional status and decreased quality of life due to debilitating deficits remain of concern. Our study aims to identify preoperative conditions predictive of undesirable outcome to help guide perioperative management. Read More

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November 2021

Feasibility and Clinical Outcomes of 48 mm Drug-Eluting Stents in the Management of Patients With Coronary Artery Disease.

J Invasive Cardiol 2021 Dec 24;33(12):E960-E967. Epub 2021 Nov 24.

Faculty of Medicine, Cardiology Department, Champlion Street, El Azarita, Alexandria, Egypt.

Background: Long coronary lesions represent a formidable challenge during percutaneous coronary intervention (PCI). Implantation of multiple contiguous stents may result in sections of overlapping stents or gaps of unstented segments and is an independent predictor of restenosis and major adverse cardiovascular events (MACEs).

Objectives: The study goal was to assess the feasibility and short-term clinical outcomes of implanting 48 mm drug-eluting stents (DESs) for the treatment of long lesions in patients with coronary artery disease (CAD). Read More

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December 2021

Genetic association analysis between IL9 and coronary artery disease in a Chinese Han population.

Cytokine 2021 Nov 20;150:155761. Epub 2021 Nov 20.

Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:

Interleukin-9 (IL-9) plays important role in coronary artery disease (CAD). However, the exact relationship between them is not explored yet. Here, four tag SNPs covering IL9 (rs31563, rs2069868, rs2069870 and rs31564) were selected to conduct case-control association analyses in a total of 3704 individuals from Chinese Han population (1863 CAD vs 1841 control). Read More

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November 2021

Diagnostic Improvements of Deep Learning-Based Image Reconstruction for Assessing Calcification-Related Obstructive Coronary Artery Disease.

Front Cardiovasc Med 2021 3;8:758793. Epub 2021 Nov 3.

State Key Laboratory of Complex Severe and Rare Diseases, Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

The objective of this study was to explore the diagnostic value of deep learning-based image reconstruction (DLR) and hybrid iterative reconstruction (HIR) for calcification-related obstructive coronary artery disease (CAD) evaluation by using coronary CT angiography (CCTA) images and subtraction CCTA images. Forty-two consecutive patients with known or suspected coronary artery disease who underwent coronary CTA on a 320-row CT scanner and subsequent invasive coronary angiography (ICA), which was used as the reference standard, were enrolled. The DLR and HIR images were reconstructed as CTA and CTA, and, based on which, the corresponding subtraction CCTA images were established as CTA and CTA, respectively. Read More

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November 2021

An in-vitro comparison of fracture resistance of three CAD/CAM Ceramic materials for fabricating Veneer.

Saudi Dent J 2021 Nov 31;33(7):745-752. Epub 2020 Mar 31.

Department of Restorative Dentistry, Ajman University, Ajman, United Arab Emirates.

Aims: This research aims to measure and compare the fracture resistance and modes of failure of the following three chemically varied computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic veneering materials: IPS e.max CAD, Vita Enamic, and Shofu HC.

Materials And Methods: Twenty-seven sound human upper premolars were collected and stored in saline at room temperature until the experiment started and were assigned to three groups at random (n = 9). Read More

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November 2021

Combined Coronary CT-Angiography and TAVR Planning for Ruling Out Significant Coronary Artery Disease: Added Value of Machine-Learning-Based CT-FFR.

JACC Cardiovasc Imaging 2021 Nov 6. Epub 2021 Nov 6.

Department of Diagnostic and Interventional Radiology, Heart Center Leipzig, Leipzig, Germany; Medical Faculty, University of Leipzig, Leipzig, Germany; Leipzig Heart Institute, Leipzig, Germany.

Objectives: To analyze the ability of machine-learning (ML)-based computed tomography (CT)-derived fractional flow reserve (CT-FFR) to further improve the diagnostic performance of coronary CT angiography (cCTA) for ruling out significant coronary artery disease (CAD) during pre-transcatheter aortic valve replacement (TAVR) evaluation in patients with a high pre-test probability for CAD.

Background: CAD is a frequent comorbidity in patients undergoing TAVR. Current guidelines recommend its assessment before TAVR. Read More

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November 2021

Combined impact of residual inflammatory risk and chronic kidney disease on long-term clinical outcomes in patients undergoing percutaneous coronary intervention.

J Cardiol 2021 Nov 16. Epub 2021 Nov 16.

Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan; Japan Agency for Medical Research and Development-Core Research for Evolutionary Medical Science and Technology (AMED-CREST), Japan Agency for Medical Research and Development, Tokyo, Japan.

Background: Inflammatory status is associated with cardiovascular events in patients with coronary artery disease (CAD) and renal function impairment. Chronic kidney disease (CKD) increases the incidence of cardiovascular events. However, whether the presence of residual inflammatory risk (RIR) and CKD together has a synergistic effect on the long-term clinical outcomes of patients with stable CAD undergoing percutaneous coronary intervention (PCI) remains unclear. Read More

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November 2021

A digital technique for a prefabricated custom post-and-core restoration.

J Prosthet Dent 2021 Nov 16. Epub 2021 Nov 16.

Associate Professor, Department of Prosthodontics, Stomatological Hospital of Xiamen Medical College, Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment, Engineering Research Center of Fujian University of Stomatological Biomaterials, Xiamen, Fujian, PR China. Electronic address:

This technique provides a prefabricated and custom post-and-core to restore endodontically treated teeth to be delivered at the preparation appointment. Cone beam computed tomography (CBCT) is used to extract the post shape from a root canal, and a computer-aided design and computer-aided manufacturing (CAD-CAM) software program is used to design the core. The post and the core are combined and milled before post space preparation. Read More

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November 2021

Screening for Asymptomatic Coronary Artery Disease Exercise Stress Testing in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Front Cardiovasc Med 2021 1;8:770648. Epub 2021 Nov 1.

Division of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital of Central South University, Changsha, China.

This meta-analysis aims to investigate the diagnostic value of exercise stress testing (EST) for asymptomatic coronary artery disease (CAD) among patients with type 2 diabetes mellitus (T2DM) and to ascertain the influence of different variables on the sensitivity and specificity of EST. Asymptomatic CAD occurs in >1 in five diabetes mellitus patients, and it is associated with an increased risk of complications. Methods for screening asymptomatic CAD in T2DM patients are still not unified. Read More

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November 2021

Effectiveness of artificial intelligent cardiac remote monitoring system for evaluating asymptomatic myocardial ischemia in patients with coronary heart disease.

Am J Transl Res 2021 15;13(10):11653-11661. Epub 2021 Oct 15.

Department of Research & Development, Lepu Medical Technology (Beijing) Co., Ltd. Beijing 102200, China.

Objective: To explore the effectiveness of cardiac remote monitoring system (CRMS) based on artificial intelligence-enabled ECG algorithm mode for evaluating asymptomatic myocardial ischemia (AMI) in patients with coronary artery disease (CAD).

Methods: Two hundred CAD patients confirmed by coronary angiography (CA) in our hospital were included as the study subjects, 120 of whom developed myocardial ischemia (MI). All patients received 12-lead telephone remote ECG monitoring and evaluation. Read More

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October 2021

Alar Base Reduction: Nuances and Techniques.

Authors:
Nazim Cerkes

Clin Plast Surg 2022 Jan 20;49(1):161-178. Epub 2021 Oct 20.

Private Practice, Hakki Yeten Cad. No:17/6, Fulya, Besiktas, Istanbul 34365, Turkey. Electronic address:

Treatment of nasal base deformities is critical for a successful rhinoplasty. Several anatomic variations are seen on nasal base. Alar base deformities can be horizontal excess or deficiency, vertical excess or deficiency, cephalic malposition or caudal malposition of alar base, wide or narrow nostril sills, and columellar base deformities. Read More

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January 2022

Adiponectin in relation to exercise and physical performance in patients with type 2 diabetes and coronary artery disease.

Adipocyte 2021 Dec;10(1):612-620

Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.

Introduction: Adipokines, expressed by adipose tissue (AT), have been associated with metabolic disturbances and coronary artery disease (CAD). The impact of exercise training on the AT in patients suffering from both diabetes and CAD is unknown. To gain knowledge on changes in ATs' inflammatory profile in such a population, we investigated the effects of long-term exercise on selected adipokines and their associations with physical performance and glucometabolic variables. Read More

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December 2021

Individual and interactive effects of chronic anthropogenic disturbance and rainfall on taxonomic, functional and phylogenetic composition and diversity of extrafloral nectary-bearing plants in Brazilian Caatinga.

Oecologia 2021 Nov 12. Epub 2021 Nov 12.

Departamento de Botânica, Universidade Federal de Pernambuco, Av. Professor Moraes Rego s/n, Cidade Universitária, Recife, PE, 50670-901, Brazil.

Chronic anthropogenic disturbance (CAD) and climate change represent two of the major threats to biodiversity globally, but their combined effects are not well understood. Here we investigate the individual and interactive effects of increasing CAD and decreasing rainfall on the composition and taxonomic (TD), functional (FD) and phylogenetic diversity (PD) of plants possessing extrafloral nectaries (EFNs) in semi-arid Brazilian Caatinga. EFNs attract ants that protect plants against insect herbivore attack and are extremely prevalent in the Caatinga flora. Read More

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November 2021

Diagnostic Performance of Dynamic Myocardial Perfusion Imaging Using Dual-Source Computed Tomography.

J Am Coll Cardiol 2021 Nov;78(20):1937-1949

Department of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.

Background: Single-center studies indicated a high diagnostic accuracy of dynamic computed tomography perfusion (CTP) imaging in the diagnosis of coronary artery disease (CAD).

Objectives: This prospective multicenter study determined the diagnostic performance of combined coronary computed tomography angiography (CTA) and CTP for detecting hemodynamically significant CAD defined by invasive coronary angiography (ICA) with fractional flow reserve (FFR).

Methods: Seven centers enrolled 174 patients with suspected or known CAD who were clinically referred for ICA. Read More

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November 2021

Comparison of diabetes to other prognostic predictors among patients referred for cardiac stress testing: A contemporary analysis from the REFINE SPECT Registry.

J Nucl Cardiol 2021 Nov 10. Epub 2021 Nov 10.

Departments of Medicine (Division of Artificial Intelligence), Imaging, and Biomedical Sciences, Cedars-Sinai, Los Angeles, CA, USA.

Background: Diabetes mellitus (DM) is increasingly prevalent among contemporary populations referred for cardiac stress testing, but its potency as a predictor for major adverse cardiovascular events (MACE) vs other clinical variables is not well delineated.

Methods And Results: From 19,658 patients who underwent SPECT-MPI, we identified 3122 patients with DM without known coronary artery disease (CAD) (DM+/CAD-) and 3564 without DM with known CAD (DM-/CAD+). Propensity score matching was used to control for the differences in characteristics between DM+/CAD- and DM-/CAD+ groups. Read More

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November 2021

Comorbid anxiety and depression, depression, and anxiety in comparison in multi-ethnic community of west China: prevalence, metabolic profile, and related factors.

J Affect Disord 2022 Feb 31;298(Pt A):381-387. Epub 2021 Oct 31.

National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Geriatric Health Care and Medical Research Center, Sichuan University, Chengdu, Sichuan Province, China. Electronic address:

Objectives: To identify the prevalence, lifestyle factors, chronic disease status, and assessing the metabolic profile, comparing key differences in a cohort of subjects aged at least 50 years old among depression combined anxiety, depression and anxiety in a multi-ethnic population in west China.

Methods: A large multi-ethnic sample of 6838 participants aged 50 years old (mean age 62.4 ± 8. Read More

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February 2022

Direct Oral Anticoagulants Combined with Antiplatelet Therapy in the Treatment of Coronary Heart Disease: An Updated Meta-analysis.

Drugs 2021 Nov 3;81(17):2003-2016. Epub 2021 Nov 3.

Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.

Background: Direct oral anticoagulants (DOACs) combined with antiplatelet therapy for acute coronary syndrome (ACS) may reduce ischemic events, but there is no consensus on bleeding risk. Moreover, the effect of DOACs on stable coronary artery disease (CAD) needs to be elucidated. We conducted a meta-analysis to summarize the efficacy and safety of DOACs combined with antiplatelet therapy in the treatment of stable CAD and ACS. Read More

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November 2021

Modulation of E-Cadherin and N-Cadherin by ovarian steroids and embryonic stimuli.

Tissue Cell 2021 Dec 21;73:101670. Epub 2021 Oct 21.

Molecular and Cellular Biology Laboratory, ICMR-National Institute for Research in Reproductive Health, Indian Council of Medical Research (ICMR), JM Street, Parel, Mumbai, 400012, India. Electronic address:

Endometrium is a dynamic tissue that undergoes extensive remodelling to attain a receptive state which is further modulated in presence of an embryo for successful initiation of pregnancy. Cadherins are the proteins of the junctional complex of which E-cadherin (E-Cad) is crucial for maintaining epithelial cell state and integrity of the epithelial barrier; gain of N-cadherin (N-Cad) in epithelial cells leads to epithelial to mesenchymal transition (EMT). In the present study, we investigated the expression of E-Cad and N-Cad in the mouse endometrial luminal epithelium and its modulation by estrogen, progesterone, and embryonic stimuli. Read More

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December 2021

Global Myocardial Work Combined with Treadmill Exercise Stress to Detect Significant Coronary Artery Disease.

J Am Soc Echocardiogr 2021 Oct 25. Epub 2021 Oct 25.

Department of Echocardiography, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

Background: Myocardial work (MW) derived from the left ventricular pressure-strain loop is a novel and noninvasive method for assessing left ventricular function that accounts for loading conditions. We aimed to explore whether global MW combined with treadmill exercise stress could detect significant coronary artery disease (CAD) in patients with angina pectoris.

Methods: Eighty-five patients with angina pectoris and no prior CAD history were included. Read More

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October 2021

Myocardial Infarction and Coronary Artery Disease in Menopausal Women With Type 2 Diabetes Mellitus Negatively Correlate With Total Serum Bile Acids.

Front Endocrinol (Lausanne) 2021 5;12:754006. Epub 2021 Oct 5.

Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Background: As metabolic molecules, bile acids (BAs) not only promote the absorption of fat-soluble nutrients, but they also regulate many metabolic processes, including the homeostasis of glucose and lipids. Although total serum BA (TBA) measurement is a readily available clinical test related to coronary artery disease (CAD), myocardial infarction (MI), and type 2 diabetes mellitus (T2DM), the relationship between TBA and these pathological conditions remain unclear, and research on this topic is inconclusive.

Methods: This study enrolled 20,255 menopausal women aged over 50 years, including 6,421 T2DM patients. Read More

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October 2021

[Two types of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy].

Zhongguo Ying Yong Sheng Li Xue Za Zhi 2021 Jan;37(1):27-33

1. Chinese Academy of Medical Sciences, Peking Union Medical College, National Center for Cardiovascular Diseases, Department of Cardiology,Fuwai Hospital, State Key Laboratory of Cardiovascular Diseases/Chinese Academy of Medical Sciences, Beijing 100037.

Insufcient exercise blood pressure response(blunted ABPR) and lower blood pressure during the recovery period (LBP)after exercise are common abnormalities in patients with hypertrophic cardiomyopathy (HCM). The purpose of this study was to analyze the related factors of these two types of abnormal blood pressure response in HCM patients and their relationship with cardiopulmonary function. A total of 219 consecutive HCM patients who underwent CPET in Fuwai hospital were recruited from April 1, 2018 to Jan 31, 2020 with a complete clinical assessment, including electrocardiography, HOLTER, rest echocardiography and cardiac MRI. Read More

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January 2021

Discovery of novel DprE1 inhibitors via computational bioactivity fingerprints and structure-based virtual screening.

Acta Pharmacol Sin 2021 Oct 19. Epub 2021 Oct 19.

Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

Decaprenylphosphoryl-β-D-ribose oxidase (DprE1) plays important roles in the biosynthesis of mycobacterium cell wall. DprE1 inhibitors have shown great potentials in the development of new regimens for tuberculosis (TB) treatment. In this study, an integrated molecular modeling strategy, which combined computational bioactivity fingerprints and structure-based virtual screening, was employed to identify potential DprE1 inhibitors. Read More

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October 2021

Hair cortisol, perceived stress, and resilience as predictors of coronary arterial disease.

Stress Health 2021 Oct 15. Epub 2021 Oct 15.

Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.

The widespread prevalence of cardiovascular disease underscores the continuing need for identifying modifiable risk factors and novel targets for therapeutic intervention. Hair cortisol concentration (HCC) is a promising biomarker for evaluating the contribution of chronic stress to the pathogenesis and prognosis of coronary arterial disease (CAD). In this cross-sectional study of 24 participants, we assessed the risk of CAD associated with HCC and with perceived chronic stress (Perceived Stress Score), controlling for the established risk factors of age, diabetes, hypertension, dyslipidemia, and obesity. Read More

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October 2021