54,512 results match your criteria cad


Evaluation of the damping capacity of common CAD/CAM restorative materials.

J Mech Behav Biomed Mater 2021 Nov 25;126:104987. Epub 2021 Nov 25.

Department of Prosthodontics, Justus-Liebig University, Schlangenzahl 14, 35392, Giessen, Germany. Electronic address:

Objectives: To evaluate and quantify the damping capacities of common CAD/CAM restorative materials (CRMs) and to assess their energy dissipation abilities by comparing loss tangent and Leeb hardness data.

Methods: Leeb hardness (HLD), together with its deduced energy dissipation data (HLD), and loss tangent values recorded via dynamic mechanical analysis (DMA) were determined for 4 ceramic, 13 composite, and 2 polymer-based CRMs as well as 1 metal. For Leeb hardness, ten indentations per material were performed on two separate specimens (12. Read More

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November 2021

Effect of post-curing time on the color stability and related properties of a tooth-colored 3D-printed resin material.

J Mech Behav Biomed Mater 2021 Nov 24;126:104993. Epub 2021 Nov 24.

Dental Research Institute and Department of Prosthodontics, School of Dentistry, Seoul National University, Seoul, 03080, Republic of Korea. Electronic address:

This study investigated the effect of post-curing time on the color stability and related properties, such as degree of conversion (DC), surface roughness, water contact angle, water sorption (W), and water solubility (W) of 3D-printed resin for dental restorations. The 3D-printed specimens were divided into four groups according to the post-curing time (0, 5, 10, and 20 min). Color changes (ΔE) of the specimens immersed in aging media were measured using a spectrophotometer at different aging times. Read More

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November 2021

Performance of a deep learning-based lung nodule detection system as an alternative reader in a Chinese lung cancer screening program.

Eur J Radiol 2021 Nov 24;146:110068. Epub 2021 Nov 24.

Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Centre of Cancer, Key Laboratory of Cancer Prevention and Therapy, Department of Radiology, Tianjin, People's Republic of China. Electronic address:

Objective: To evaluate the performance of a deep learning-based computer-aided detection (DL-CAD) system in a Chinese low-dose CT (LDCT) lung cancer screening program.

Materials And Methods: One-hundred-and-eighty individuals with a lung nodule on their baseline LDCT lung cancer screening scan were randomly mixed with screenees without nodules in a 1:1 ratio (total: 360 individuals). All scans were assessed by double reading and subsequently processed by an academic DL-CAD system. Read More

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November 2021

Improving Familial Hypercholesterolemia Diagnosis Using an EMR-based Hybrid Diagnostic Model.

J Clin Endocrinol Metab 2021 Dec 6. Epub 2021 Dec 6.

Northern Kentucky University Department of Mathematics and Statistics, Highland Heights, KY.

Background: Familial hypercholesterolemia (FH) confers a greatly increased risk for premature cardiovascular disease (CVD), but remains very under-diagnosed and under-treated in primary care populations. We assessed whether using a hybrid model consisting of two existing FH diagnostic criteria coupled with electronic medical record (EMR) data, would accurately identify patients with FH in a midwest US metropolitan healthcare system.

Methods And Results: We conducted a retrospective, records-based, cross-sectional study using datasets from unique EMRs of living patients. Read More

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December 2021

Functional Coronary Artery Assessment: a Systematic Literature Review.

Wien Klin Wochenschr 2021 Dec 6. Epub 2021 Dec 6.

Software Innovation Laboratory, Graduate Program in Applied Computing, Universidade do Vale do Rio dos Sinos, São Leopoldo, Brazil.

Cardiovascular diseases represent the number one cause of death in the world, including the most common disorders in the heart's health, namely coronary artery disease (CAD). CAD is mainly caused by fat accumulated in the arteries' internal walls, creating an atherosclerotic plaque that impacts the blood flow functional behavior. Anatomical plaque characteristics are essential but not sufficient for a complete functional assessment of CAD. Read More

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December 2021

Cancer Risk Estimation Combining Lung Screening CT with Clinical Data Elements.

Radiol Artif Intell 2021 Nov 13;3(6):e210032. Epub 2021 Oct 13.

Departments of Computer Science (R.G., K.X., Y.H., B.A.L.) and Electrical and Computer Engineering (Y.T., Y.H., B.A.L.), Vanderbilt University, 400 24th Ave S, Featheringill Hall, Room 371, Nashville, TN 37235; and Departments of Radiology and Radiological Sciences (A.B.P., K.L.S.), Thoracic Surgery (S.S., S.D.), General Internal Medicine and Public Health (M.S.K.), Biomedical Informatics (M.S.K.), and Medicine, Division of Allergy, Pulmonary and Critical Care Medicine (P.P.M.), Vanderbilt University Medical Center, Nashville, Tenn.

Purpose: To develop a model to estimate lung cancer risk using lung cancer screening CT and clinical data elements (CDEs) without manual reading efforts.

Materials And Methods: Two screening cohorts were retrospectively studied: the National Lung Screening Trial (NLST; participants enrolled between August 2002 and April 2004) and the Vanderbilt Lung Screening Program (VLSP; participants enrolled between 2015 and 2018). Fivefold cross-validation using the NLST dataset was used for initial development and assessment of the co-learning model using whole CT scans and CDEs. Read More

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November 2021

Fast-Strain Encoded Cardiac Magnetic Resonance During Vasodilator Perfusion Stress Testing.

Front Cardiovasc Med 2021 17;8:765961. Epub 2021 Nov 17.

Department of Cardiology, Vascular Medicine and Pneumology, Gesundheitszentren Rhein-Neckar (GRN) Hospital Weinheim, Weinheim, Germany.

Cardiac magnetic resonance perfusion imaging during vasodilator stress is an established modality in patients with suspected and known coronary artery disease (CAD). This study aimed to evaluate the performance of fast-Strain-Encoded-MRI (fast-SENC) for the diagnostic classification and risk stratification of patients with ischemic heart disease. Perfusion and fast-SENC cardiac magnetic resonance (CMR) images were retrospectively analyzed in 111 patients who underwent stress CMR. Read More

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November 2021

Phenotypic Clustering of Patients With Newly Diagnosed Coronary Artery Disease Using Cardiovascular Magnetic Resonance and Coronary Computed Tomography Angiography.

Front Cardiovasc Med 2021 18;8:760120. Epub 2021 Nov 18.

Institut Cardiovasculaire Paris Sud, Cardiovascular Magnetic Resonance Laboratory, Hôpital Privé Jacques CARTIER, Ramsay Santé, Massy, France.

Epidemiological characteristics and prognostic profiles of patients with newly diagnosed coronary artery disease (CAD) are heterogeneous. Therefore, providing individualized cardiovascular (CV) risk stratification and tailored prevention is crucial. Phenotypic unsupervised clustering integrating clinical, coronary computed tomography angiography (CCTA), and cardiac magnetic resonance (CMR) data were used to unveil pathophysiological differences between subgroups of patients with newly diagnosed CAD. Read More

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November 2021

The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation.

Front Cardiovasc Med 2021 19;8:756552. Epub 2021 Nov 19.

Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

The connection between revascularization for coronary artery disease (CAD) and the incidence of recurrent events of atrial fibrillation (AF) after ablation is unclear. This study aimed to explore the relationship between coronary revascularization and AF recurrence in patients who underwent radiofrequency catheter ablation (RFCA). Four hundred and nineteen patients who underwent performed coronary angiography at the same time as RFCA were enrolled in this study. Read More

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November 2021

Gender-Related Differences in Chest Pain Syndromes in the Frontiers in CV Medicine Special Issue: Sex & Gender in CV Medicine.

Front Cardiovasc Med 2021 17;8:744788. Epub 2021 Nov 17.

Barbra Streisand Women's Heart Center, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, United States.

Coronary artery disease (CAD) is the leading cause of morbidity and mortality among both women and men, yet women continue to have delays in diagnosis and treatment. The lack of recognition of sex-specific biological and socio-cultural gender-related differences in chest pain presentation of CAD may, in part, explain these disparities. Sex and gender differences in pain mechanisms including psychological susceptibility, the autonomic nervous system (ANS) reactivity, and visceral innervation likely contribute to chest pain differences. Read More

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November 2021

Associations of Insomnia With Hypertension and Coronary Artery Disease Among Patients With Type 2 Diabetes Mellitus.

Front Cardiovasc Med 2021 19;8:730654. Epub 2021 Nov 19.

National Health Commission (NHC), Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China.

This study aimed to determine whether insomnia is associated with hypertension (HBP) and coronary artery disease (CAD) in a hospital-based sample of patients with type 2 diabetes mellitus (T2DM). Our present study included 354 patients with T2DM. According to the diagnostic criteria of insomnia, the participants were assigned to three groups based on the duration of T2DM and insomnia diagnosis. Read More

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November 2021

Acute Hemodynamic Responses to Enhanced External Counterpulsation in Patients With Coronary Artery Disease.

Front Cardiovasc Med 2021 12;8:721140. Epub 2021 Nov 12.

Department of Cardiology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.

Enhanced external counterpulsation is a non-invasive treatment that increases coronary flow in patients with coronary artery disease (CAD). However, the acute responses of vascular and blood flow characteristics in the conduit arteries during and immediately after enhanced external counterpulsation (EECP) need to be verified. Forty-two patients with CAD and 21 healthy controls were recruited into this study to receive 45 min-EECP. Read More

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November 2021

Transcriptome Profiling of the Salt Stress Response in the Leaves and Roots of Halophytic .

Front Genet 2021 18;12:770742. Epub 2021 Nov 18.

Shandong Provincial Key Laboratory of Plant Stress Research, College of Life Science, Shandong Normal University, Jinan, China.

can grow in natural harsh environments; however, the underlying mechanisms for salt tolerance of need to be further understood. Herein, the transcriptome profiling of leaves and roots exposed to 300 mM NaCl is investigated, and the result emphasized the role of genes involved in lignin biosynthesis, autophagy, peroxisome, and sugar metabolism upon salt stress. Furthermore, the expression of the lignin biosynthesis and autophagy-related genes, as well as 16 random selected genes, was validated by qRT-PCR. Read More

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November 2021

Transcriptomic, Proteomic, and Metabolic Profiles of Tension Wood Reveal New Insight Into Lignin Biosynthesis Involving Transcription Factor Regulation.

Front Plant Sci 2021 15;12:704262. Epub 2021 Nov 15.

Xiaolongshan Research Institute of Forest Science and Technology, Tianshui, China.

Lignin is a complex polymer in plant cell walls whose proportion is second only to that of cellulose and plays an important role in the mechanical properties of wood and stress resistance of plants. Here, we induced tension wood (TW) formation in by artificial bending and analyzed the lignin metabolism of the TW. LC-MS analysis showed that a significantly higher content of coniferyl aldehyde was observed in the TW cell wall than in the opposite wood (OW) and normal wood (NW) cell walls. Read More

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November 2021

Metabolomic Characterization of Fatty Acids in Patients With Coronary Artery Ectasias.

Front Physiol 2021 19;12:770223. Epub 2021 Nov 19.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

We used a targeted metabolomics approach to identify fatty acid (FA) metabolites that distinguished patients with coronary artery ectasia (CAE) from healthy Controls and patients with coronary artery disease (CAD). Two hundred fifty-two human subjects were enrolled in our study, such as patients with CAE, patients with CAD, and Controls. All the subjects were diagnosed by coronary angiography. Read More

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November 2021

Diagnosis of multiple sclerosis using multifocal ERG data feature fusion.

Inf Fusion 2021 Dec;76:157-167

Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain.

The purpose of this paper is to implement a computer-aided diagnosis (CAD) system for multiple sclerosis (MS) based on analysing the outer retina as assessed by multifocal electroretinograms (mfERGs). MfERG recordings taken with the RETI-port/scan 21 (Roland Consult) device from 15 eyes of patients diagnosed with incipient relapsing-remitting MS and without prior optic neuritis, and from 6 eyes of control subjects, are selected. The mfERG recordings are grouped (whole macular visual field, five rings, and four quadrants). Read More

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December 2021

Minimal AR: visual asset optimization for the authoring of augmented reality work instructions in manufacturing.

Int J Adv Manuf Technol 2021 Nov 30:1-16. Epub 2021 Nov 30.

Department of Mechanics, Mathematics, and Management, Polytechnic Institute of Bari, via Orabona, 4, 70125 Bari, Italy.

This work investigates the possibility of using a novel "minimal AR" authoring approach to optimize the visual assets used in augmented reality (AR) interfaces to convey work instructions in manufacturing. In the literature, there are no widely supported guidelines for the optimal choice of visual assets (e.g. Read More

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November 2021

Two-dimensional speckle tracking echocardiography derived post systolic shortening in patients with unstable angina and normal left ventricular systolic function.

Anatol J Cardiol 2021 Dec;25(12):880-886

Department of Cardiology, Mahatma Gandhi medical college and research institute, Puducherry, India.

Objectives: Post systolic shortening (PSS) had been shown to be sensitive in detecting ischemia on stress echocardiography. This work aims to study the diagnostic potential of resting PSS and post systolic index (PSI) in patients with suspected unstable angina (UA).

Methods: Total of 159 participants with suspected UA without any wall motion abnormalities were recruited. Read More

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December 2021

Long-term prognostic value of vasodilator stress cardiac magnetic resonance in patients with atrial fibrillation.

ESC Heart Fail 2021 Dec 6. Epub 2021 Dec 6.

Department of Internal Medicine/Cardiology, German Heart Center Berlin, Augustenburgerplatz 1, Berlin, 13533, Germany.

Aims: Although the prevalence of coronary artery disease (CAD) is high among patients with atrial fibrillation (AF), studies on stress perfusion cardiac magnetic resonance (CMR) imaging frequently exclude patients with AF, and its prognostic and diagnostic value in high-risk patients with suspected or known CAD remains unclear.

Methods And Results: In this longitudinal cohort study, we included 164 consecutive patients with AF during vasodilator perfusion CMR. Diagnostic value was evaluated regarding invasive coronary angiography in a subset of patients. Read More

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December 2021

Clinical effects with customized brackets and CAD/CAM technology: a prospective controlled study.

Prog Orthod 2021 Dec 6;22(1):40. Epub 2021 Dec 6.

Department of Orthodontics and Dentofacial Orthopedics, University Hospital, LMU Munich, Goethestrasse 70, 80336, Munich, Germany.

Objective: Nowadays, CAD/CAM technologies enrich orthodontics in several ways. While they are commonly used for diagnoses and treatment planning, they can also be applied to create individualized bracket systems. The purpose of this prospective quasi-randomized study was to evaluate the clinical efficiency of a customized bracket system and its comparison with directly bonded conventional self-ligating bracket treatment. Read More

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December 2021

Cardiovascular risks associated with use of non-steroidal anti-inflammatory drugs in patients with non-obstructive coronary artery disease.

Eur Heart J Cardiovasc Pharmacother 2021 Dec 4. Epub 2021 Dec 4.

Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.

Aim: To examine whether non-aspirin non-steroidal anti-inflammatory drugs (NSAID) use is associated with increased cardiovascular risks in patients with non-obstructive coronary artery disease (CAD).

Methods And Results: Using Danish medical registries, we conducted a population-based cohort study in Western Denmark during 2008-2017. We identified all patients undergoing first-time coronary computed tomography angiography (CCTA) due to suspected CAD (n = 35,399), with results showing no (n = 28,581) or non-obstructive CAD (n = 6,818). Read More

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December 2021

Management of antithrombotics in situations with a gap in evidence: A national French survey focusing on patients with coronary artery disease and atrial fibrillation.

Int J Cardiol 2021 Dec 2. Epub 2021 Dec 2.

Department of Cardiology, Hôpital Européen Georges Pompidou, AP-HP, University of Paris, FACT (French Alliance for Cardiovascular Trials), Paris, France.

Background: If several randomized studies allowed to better apprehend what should be the best antithrombotic strategy in patients with concomitant coronary artery disease (CAD) and atrial fibrillation (AF), there are still several clinical situations with a gap of evidence.

Methods: We conducted a national French survey in September-October 2020 among cardiologists in order to assess what are daily practices regarding the antithrombotic management in several specific clinical settings where no or little scientific evidence is available. The questionnaires were built by a committee of 6 cardiologists routinely involved in the field of CAD and/or AF. Read More

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December 2021

Clinical Characteristics and Short-Term Outcomes of Middle-Eastern Patients Presenting with Acute Myocardial Infarction - Multi-vessel disease reference A Single Tertiary-Care Center Experience.

Indian Heart J 2021 Dec 2. Epub 2021 Dec 2.

King Abdullah Mediacl City- Makkah, Saudi Arabia; Zagazige University- Egypt. Electronic address:

Objective: Patients with multi-vessel coronary artery disease (MVD) compared to single-vessel coronary artery disease (CAD) have more comorbidities and poor in-hospital outcomes. We aim to analyze MVD-AMI patients regarding clinical data and short-term outcomes.

Methods: This is a retrospective analysis of the prospectively collected data registry, a single-center study reviewing the clinical details and hospital outcome measures of AMI patients referred to our center for early revascularization from 2016 to 2019. Read More

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December 2021

Investigation of the effect of anticoagulant usage in the flow diverter stent treatment of the patient-specific cerebral aneurysm using the Lagrangian coherent structures.

J Clin Neurosci 2021 Dec 16;94:86-93. Epub 2021 Oct 16.

Uludag University School of Medicine, Department of Radiology, Gorukle, Bursa 16059, Turkey.

Anticoagulants are prescribed to the flow diverter treated patients to diminish the risk of embolism in the arteries. In the present study, digital subtraction angiography images of a 49-year-old female patient with a left paraophthalmic aneurysm were used to build a numerical model to investigate the effect of an anticoagulant on hemodynamics at the aneurysm site. The Carreau-Yasuda viscosity model was utilized to define blood viscosity, and the coefficients of the viscosity model were updated based on the usage of warfarin. Read More

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December 2021

Three-dimensional liquid chromatography with parallel second dimensions and quadruple parallel mass spectrometry for adult/infant formula analysis.

J Chromatogr A 2021 Nov 22;1661:462682. Epub 2021 Nov 22.

Charles University, Faculty of Pharmacy, Dept. of Analytical Chemistry, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

Three dimensions of chromatographic separation, using split-flow two-dimensional liquid chromatography (SF-2D-LC) with two parallel second dimensions, LC × 2LC, combined with quadruple parallel mass spectrometry (LC3MS4) is demonstrated for analysis of NIST SRM 1849a adult/infant formula. The first dimension, D, was a conventional non-aqueous reversed-phase (NARP) HPLC separation using two C18 columns in series, followed by detection using an ultraviolet (UV) detector, a fluorescence detector (FLD), with flow then split to a corona charged aerosol detector (CAD), and then dual parallel mass spectrometry (MS), conducted in atmospheric pressure photoionization (APPI) and electrospray ionization (ESI) modes. The first second dimension, D(1), UHPLC was conducted on a 50. Read More

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November 2021

The D.A.M.A. Project at Terni Hospital, Italy.

Psychiatr Danub 2021 Dec;33(Suppl 11):91-95

Clinical Neurophysiology Division, Neuroscience Department, St. Maria Hospital, Terni, Italy,

Experience shows how difficult it is for a person with disabilities to cope with the reality of a hospital, especially if he or she has an intellectual disability. The difficulty in carrying out even simple diagnostic and therapeutic manoeuvres, the complexity of the pathologies, the difficulty in relating to the patient all make it a real risk that many medical problems of patients with disabilities are overlooked or denied altogether. The person with a disability has the right to all care, not only that related to his or her particular pathology, but also that required for other specialist or general pathologies. Read More

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December 2021

Analysis of Biofilm Adhesion on CAD/CAM Lithium Disilicates Under Different Types of Intraoral Polishing.

Eur J Prosthodont Restor Dent 2021 Nov 16. Epub 2021 Nov 16.

São Paulo State University (UNESP), School of Dentistry, Araçatuba.

Purpose: To evaluate the adhesion of Streptococcus mutans (S. mutans) on lithium disilicate ceramics, submitted to different intraoral polishing protocols, and the degree of surface smoothness obtained.

Materials And Methods: Fifty lithium disilicate specimens were divided into 5 groups (n=10): G1-Glaze Group (positive control); G2-Glaze Group + Wear + Glaze; G3-Wear Group (negative control); G4-Ceramisté Wear Group; G5-Optrafine Wear Group. Read More

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November 2021

Evaluation of Various Polishing Systems for Lithium Disilicate Glass-Ceramics.

Eur J Prosthodont Restor Dent 2021 Nov 30. Epub 2021 Nov 30.

Department of Prosthodontics and Research Institute of Oral Science, College of Dentistry, Gangneung-Wonju National University.

Objective: The aim of this study was to investigate the surface roughness of lithium disilicates (LS2s) polished using various polishing systems.

Materials And Methods: Two types of LS2 (A, Amber Mill and E, IPS e.max CAD) were polished using LS2-specific polishing systems (L-Edenta, L-Jota), a zirconia-specific polishing system (Z-Jota), and a conventional ceramic polishing system (P-Shofu) (n = 8 per group). Read More

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November 2021

Reconstruction of medium-size defects of the oral cavity: radial forearm free flap vs facial artery musculo-mucosal flap.

J Otolaryngol Head Neck Surg 2021 Dec 3;50(1):67. Epub 2021 Dec 3.

Division of Otolaryngology-Head and Neck Surgery, Université de Montréal, Hôpital Maisonneuve-Rosemont, Montreal, Canada.

Background: The radial forearm free flap (RFFF) is the most commonly used flap for defects of the oral cavity. The facial artery musculomucosal (FAMM) is a safe and effective method to reconstruct medium sized defects of the oral cavity. No comparison exists between the FAMM flap and RFFF. Read More

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December 2021

Texture appearance model, a new model-based segmentation paradigm, application on the segmentation of lung nodule in the CT scan of the chest.

Comput Biol Med 2021 Nov 29;140:105086. Epub 2021 Nov 29.

Institute of Electronics and Telecommunications, Peter the Great St.Petersburg Polytechnic University, Saint-Petersburg, Russia.

Lung cancer causes more than one million deaths worldwide each year. Averages of 5-year survival rate of patients with Non-small cell lung cancer (NSCLC), which is the most common type of lung cancer, is 15%. Computer-Aided Detection (CAD) is a very important tool for identifying lung lesions in medical imaging. Read More

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November 2021