7 results match your criteria btk calibration

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Comparison of angiographic and intravascular ultrasound vessel measurements in infra-popliteal endovascular interventions: The below-the-knee calibration study.

Cardiovasc Revasc Med 2021 Sep 16. Epub 2021 Sep 16.

Cardiology, NC Heart and Vascular Research, LLC, UNC School of Medicine, Raleigh, NC, USA. Electronic address:

Background: Endovascular revascularization (ER) via percutaneous transluminal angioplasty (PTA) and stenting are viable options for revascularization in below-the-knee (BTK) peripheral arterial disease. Two-dimensional angiography has been the standard of practice for estimating vessel size and selecting treatment devices during ER. However, in other vascular territories, intravascular ultrasound (IVUS) offers better visualization of the lumen dimensions. Read More

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September 2021

Comprehensive analyses of the heterogeneity and prognostic significance of tumor-infiltrating immune cells in non-small-cell lung cancer: Development and validation of an individualized prognostic model.

Int Immunopharmacol 2020 Sep 2;86:106744. Epub 2020 Jul 2.

Institute of Oncology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250021, China; Department of Thoracic Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250021, China; Institute of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China. Electronic address:

Understanding the role of tumor-infiltrating immune cells (TIICs) in non-small cell lung cancer (NSCLC) is critical to finding new prognostic biomarkers and improving prognostic evaluation. Herein, we aimed to comprehensively analyze tumor-infiltrating pattern of TIICs in NSCLC and build a TIICs-associated, risk-stratification prognostic model for clinical practice. We applied CIBERSORT and ESTIMATE computational methods to analyze RNA-seq samples of 852 NSCLC patients from The Cancer Genome Atlas (TCGA). Read More

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September 2020

Liquid chromatography-tandem mass spectrometric assay for the simultaneous determination of the irreversible BTK inhibitor ibrutinib and its dihydrodiol-metabolite in plasma and its application in mouse pharmacokinetic studies.

J Pharm Biomed Anal 2016 Jan 27;118:123-131. Epub 2015 Oct 27.

Utrecht University, Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology & Clinical Pharmacology, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.

A validated simple, fast and sensitive bio-analytical assay for ibrutinib and its dihydrodiol metabolite in human and mouse plasma was set up. Sample preparation was performed by protein precipitation, and addition of the respective deuterated internal standards, followed by LC-MS/MS analysis. Separation was performed on a 3. Read More

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January 2016

NIR techniques create added values for the pellet and biofuel industry.

Bioresour Technol 2009 Feb 25;100(4):1589-94. Epub 2008 Oct 25.

Unit of Biomass Technology and Chemistry, Swedish University of Agricultural Sciences, P.O. Box 4097, SE-903 04 Umeå, Sweden.

A 2(3)-factorial experiment was carried out in an industrial plant producing biofuel pellets with sawdust as feedstock. The aim was to use on-line near infrared (NIR) spectra from sawdust for real time predictions of moisture content, blends of sawdust and energy consumption of the pellet press. The factors varied were: drying temperature and wood powder dryness in binary blends of sawdust from Norway spruce and Scots pine. Read More

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February 2009

Hyperspectral NIR imaging for calibration and prediction: a comparison between image and spectrometer data for studying organic and biological samples.

Analyst 2006 Oct 21;131(10):1152-60. Epub 2006 Jul 21.

Unit of Biomass Technology and Chemistry, Swedish University of Agricultural Sciences, SLU Röbäcksdalen, PO Box 4097, SE 90403 Umeå, Sweden.

A hyperspectral image in the near infrared contains thousands of position-referenced spectra. After imaging reference materials of known composition it is possible to build Partial Least Squares (PLS) regression models for predicting unknown compositions from new images or spectra. In this paper a comparison is made between spectra from a hyperspectral image and spectra from two spectrometers: a scanning grating instrument with rotating sample holders and an FT-NIR instrument utilizing a fiber-optic probe. Read More

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October 2006

Multivariate NIR spectroscopy models for moisture, ash and calorific content in biofuels using bi-orthogonal partial least squares regression.

Analyst 2005 Aug 29;130(8):1182-9. Epub 2005 Jun 29.

Unit of Biomass Technology and Chemistry, Swedish University of Agricultural Sciences, P.O. Box 4097, SE 904 03 Umeå, Sweden.

The multitude of biofuels in use and their widely different characteristics stress the need for improved characterisation of their chemical and physical properties. Industrial use of biofuels further demands rapid characterisation methods suitable for on-line measurements. The single most important property in biofuels is the calorific value. Read More

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Escherichia coli K-1 interaction with human brain micro-vascular endothelial cells triggers phospholipase C-gamma1 activation downstream of phosphatidylinositol 3-kinase.

J Biol Chem 2003 Nov 2;278(46):45753-62. Epub 2003 Sep 2.

Division of Infectious Diseases and Congressman Dixon Image Core, Childrens Hospital Los Angeles, California, USA.

Escherichia coli, the most common Gram-negative bacterium that causes meningitis in neonates, invades human brain microvascular endothelial cells (HBMEC) by rearranging host cell actin via the activation of phosphatidylinositol 3-kinase (PI3K) and PKC-alpha. Here, further, we show that phospholipase (PLC)-gamma1 is phosphorylated on tyrosine 783 and condenses at the HBMEC membrane beneath the E. coli entry site. Read More

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November 2003
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