11,379 results match your criteria bpd

Very preterm infants admitted to a tertiary neonatal unit in central Vietnam showed poor postnatal growth.

Acta Paediatr 2021 Sep 18. Epub 2021 Sep 18.

Department of Paediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.

Aim: We aimed to evaluate the postnatal growth of very preterm infants.

Methods: This was a cross-sectional observational study of neonates born before 32 weeks of gestation and admitted to the neonatal unit at Da Nang Hospital for Women and Children, Vietnam, between 1 February 2020 and 30 September 2020. Morbidities, therapies, nutrition modalities and growth status were recorded from admission to discharge. Read More

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September 2021

A meta-analysis of theory of mind and 'mentalization' in borderline personality disorder: a true neuro-social-cognitive or meta-social-cognitive impairment?

Emre Bora

Psychol Med 2021 Sep 17:1-11. Epub 2021 Sep 17.

Department of Psychiatry, Dokuz Eylul University Medical School, Izmir35340, Turkey.

Background: It is widely accepted that borderline personality disorder (BPD) is associated with significant impairments in mentalization and theory of mind (ToM) which are considered as closely related concepts by many authors particularly in psychoanalytical circles. However, for understanding interpersonal difficulties in personality disorders, it is important to distinguish neuro-social cognitive impairment from the abnormal meta-social-cognitive style of patients.

Methods: The current systematic review aimed to conduct separate meta-analyses of 'mentalization' [reflective functioning (RF] and different aspects of ToM in BPD. Read More

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September 2021

Can high-flow nasal cannula reduce the risk of bronchopulmonary dysplasia compared with CPAP in preterm infants? A systematic review and meta-analysis.

BMC Pediatr 2021 Sep 16;21(1):407. Epub 2021 Sep 16.

Physiotherapy Department, Postgraduate Program in Rehabilitation and functional performance, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Campus JK - Diamantina/MG, Rodovia MGT 367 - Km 583, n° 5.000 Alto da Jacuba, Diamantina, Minas Gerais, 39100-000, Brazil.

Background: Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects the premature lung, and to reduce its incidence has been used non-invasive ventilatory support, such as continuous positive airway (CPAP) and high-flow nasal cannula (HFNC). Thus, the objective of this review was to assess whether the use of high flow nasal cannula (HFNC) compared to continuous positive airway pressure (CPAP) decreases the risk of bronchopulmonary dysplasia (BPD) in premature newborns.

Methods: The protocol was registered (Prospero: CRD42019136631) and the search was conducted in the MEDLINE, PEDro, Cochrane Library, CINAHL, Embase, and LILACS databases, and in the clinical trials registries, until July 2020. Read More

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September 2021

MicroRNA-214 promotes alveolarization in neonatal rat models of bronchopulmonary dysplasia via the PlGF-dependent STAT3 pathway.

Mol Med 2021 Sep 16;27(1):109. Epub 2021 Sep 16.

Department of Neonatology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310000, Zhejiang Province, People's Republic of China.

Background: Recently, the role of several microRNAs (miRNAs or miRs) in pulmonary diseases has been described. The molecular mechanisms by which miR-214 is possibly implicated in bronchopulmonary dysplasia (BPD) have not yet been addressed. Hence, this study aimed to investigate a putative role of miR-214 in alveolarization among preterm neonates with BPD. Read More

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September 2021

Riociguat can ameliorate bronchopulmonary dysplasia in the SU5416 induced rat experimental model.

Exp Lung Res 2021 Sep 16:1-8. Epub 2021 Sep 16.

Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.

Background: Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature neonates. Classical BPD is caused by hyperoxia and high-pressure mechanical ventilation, whereas BPD in recent era is caused by impaired pulmonary angiogenesis and alveolarization in extreme prematurity. Although sildenafil was reported to be effective in a hyperoxia-induced rat BPD model, several clinical trials could not demonstrate any significant improvement in the respiratory statuses of BPD infants. Read More

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September 2021

Four Novel d Metal-Organic Frameworks Incorporating Amino-Functionalized Carboxylate Ligands: Synthesis, Structures, and Fluorescence Properties.

Front Chem 2021 30;9:708314. Epub 2021 Aug 30.

Key Laboratory of Flexible Electronics & Institute of Advanced Materials, Jiangsu National Synergistic Innovation Center for Advanced Materials, School of Energy Science and Engineering, Nanjing Tech University, Nanjing, China.

By employment of amino-functionalized dicarboxylate ligands to react with d metal ions, four novel metal-organic frameworks (MOFs) were obtained with the formula of {[Cd(BCPAB)( -HO)]} (1), {[Cd(BDAB)]∙2HO∙DMF} (2), {[Zn(BDAB)(BPD)(HO)]∙2HO} (3) and {[Zn(BDAB)(DBPB)(HO)]∙2HO} (4) (HBCPAB = 2,5-bis(p-carbonylphenyl)-1-aminobenzene; HBDAB = 1,2-diamino-3,6-bis(4-carboxyphenyl)benzene); BPD = (4,4'-bipyridine); DBPB = (2,5-dimethoxy-1,4-bis-[2-pyridin-vinyl]-benzene; DMF = ,-dimethylformamide). Complex 1 is a three-dimensional (3D) framework bearing -3,5- nets with point symbol of {4.6}{4. Read More

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An Experimental Model of Bronchopulmonary Dysplasia Features Long-Term Retinal and Pulmonary Defects but Not Sustained Lung Inflammation.

Front Pediatr 2021 30;9:689699. Epub 2021 Aug 30.

Leukocyte Signalling Laboratory, Department of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, VIC, Australia.

Bronchopulmonary dysplasia (BPD) is a severe lung disease that affects preterm infants receiving oxygen therapy. No standardized, clinically-relevant BPD model exists, hampering efforts to understand and treat this disease. This study aimed to evaluate and confirm a candidate model of acute and chronic BPD, based on exposure of neonatal mice to a high oxygen environment during key lung developmental stages affected in preterm infants with BPD. Read More

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Emotional dysfunction in avoidant personality disorder and borderline personality disorder: A cross-sectional comparative study.

Scand J Psychol 2021 Sep 15. Epub 2021 Sep 15.

Psychiatry, Aalborg University Hospital, Aalborg, Denmark.

According to the literature, avoidant personality disorder (APD) is often overlooked in research on personality disorders. In the present study, patients with APD were compared to patients with borderline personality disorder (BPD) with respect to emotional dysfunction. Emotional dysfunction was operationalized through the Affect Integration Inventory. Read More

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September 2021

[Parental support, parental self-efficacy and borderline personality features in adolescents].

Tijdschr Psychiatr 2021 ;63(7):543-549

Background: Parenting an adolescent with borderline personality disorder (BPD) features can be challenging due to, for example, emotional dysregulation, impulsivity and/or self-destructive behavior. Parents confronted with challenging behavior of their child, may experience less parental-self-efficacy (PSE). Subsequently this lower PSE might strengthen the relationship between low parental support and BPD features. Read More

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September 2021

The Impact of Infant and Maternal Factors on Oral Feeding Performance in Premature Infants.

Phys Occup Ther Pediatr 2021 Sep 14:1-7. Epub 2021 Sep 14.

School of Rehabilitation Therapy, Queens University, Kingston, Ontario, Canada.

To identify infant and maternal factors associated with attainment of full oral feeding (FOF) in premature infants. A retrospective study was performed on 89 premature infants (<34 weeks gestational age) from a tertiary care neonatal intensive care unit (NICU). Infant and maternal factors were concurrently assessed. Read More

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September 2021

A gastric outlet thickened mucosal fold associated with cytomegalovirus infection in an extremely preterm infant managed by surgical resection.

Paediatr Int Child Health 2021 Sep 14:1-4. Epub 2021 Sep 14.

Department of Neonatology, Sri Ramachandra Institute of Higher Education & Research, Chennai, India.

Non-bilious vomiting in preterm neonates discharged from neonatal intensive care units is a common complaint and is often associated with benign conditions such as gastro-oesophageal reflux. A neonate of 27 weeks gestation who presented later with vomiting owing to gastric outlet obstruction is described. He was discharged at 11 weeks of age and required re-admission 1 week later. Read More

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September 2021

Effects of Dialectical Behavior Therapy on reducing self-harming behaviors and negative emotions in patients with Borderline Personality Disorder: A meta-analysis.

J Psychiatr Ment Health Nurs 2021 Sep 14. Epub 2021 Sep 14.

Department of Nursing, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.

Introduction: Dialectical behavior therapy(DBT) has been widely used for borderline personality disorder(BPD). Existing studies are limited to behaviors such as self-harm , and the results for reducing self-harm were controversial. Few have systematically evaluated the effect of DBT on self-harming behaviors and negative emotions. Read More

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September 2021

Effect of Enteral Vitamin A on Fecal Calprotectin in Extremely Preterm Infants: A Nested Prospective Observational Study.

Neonatology 2021 Sep 10:1-7. Epub 2021 Sep 10.

Neonatal Clinical Care Unit, King Edward Memorial and Perth Children's Hospitals, Perth, Washington, Australia.

Background: Vitamin A has anti-inflammatory and immune-modulating properties. We aimed to assess whether enteral water-soluble vitamin A supplementation in extremely preterm infants decreases fecal calprotectin, a marker of intestinal inflammation.

Methods: This was a prospective observational study nested in a randomized, double-blind, placebo-controlled clinical trial investigating enteral vitamin A (5,000 IU/day) for reducing the severity of bronchopulmonary dysplasia (BPD) in extremely preterm infants. Read More

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September 2021

Imaging associations of self-injurious behaviours amongst patients with Borderline Personality Disorder: A mini-review.

J Affect Disord 2021 Aug 31;295:781-787. Epub 2021 Aug 31.

Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy.

Background: Borderline Personality Disorder (BPD) is a severe and disabling psychiatric syndrome, frequently associated with self-injurious behaviours (SIB). In recent years, functional magnetic resonance imaging (fMRI) investigations have tried to identify alterations associated with SIB amongst BPD patients, in order to better delineate possible neurobiological underpinnings of these manifestations. In this mini-review, we aimed at summarizing fMRI studies exploring patterns of neural activation associated with SIB in BPD patients. Read More

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Brief psychiatric treatment for borderline personality disorder as a first step of care: Adapting general psychiatric management to a 10-session intervention.

Personal Disord 2021 Sep 13. Epub 2021 Sep 13.

Gunderson Personality Disorders Institute.

The considerable demand versus supply gap of evidence-based treatments for borderline personality disorder (BPD) indicates the need for modular steps of care to tailor fit between individual patients' needs along the trajectory of their clinical course and effective interventions. These trajectories may or may not include lengthy specialized psychotherapies. Good psychiatric management (GPM) for BPD is being practiced by an increasing number of mental health professionals as a basic starting block of mental health services in the community. Read More

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September 2021

A scoping review on studies about the quality of life of informal caregivers of stroke survivors.

Qual Life Res 2021 Sep 13. Epub 2021 Sep 13.

EPIUnit-Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.

Purpose: To assess the available evidence regarding the quality of life (QoL) of informal caregivers of stroke survivors, by identifying the instruments used to assess QoL, and its associated characteristics.

Methods: A scoping review was performed, following PRISMA-ScR guidelines. The electronic databases PubMed, ISI Web of Science, PsycINFO, and SciELO were searched for empirical, peer-reviewed, original, and full-length studies on the characteristics influencing the QoL of informal caregivers of stroke survivors. Read More

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September 2021

Introduction of a Quality Improvement Bundle Is Associated with Reduced Exposure to Mechanical Ventilation in Very Preterm Infants.

Neonatology 2021 Sep 1:1-8. Epub 2021 Sep 1.

Department of Paediatrics, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia.

Introduction: Exposure to mechanical ventilation (MV) is a risk factor for bronchopulmonary dysplasia (BPD) in very preterm infants (VPTIs). We assessed the impact of a quality improvement (QI) bundle in VPTIs (<32 week gestation) on exposure to MV.

Methods: We introduced a QI bundle consisting of deferred cord clamping (DCC), nasal bubble continuous positive airway pressure (bCPAP) in the delivery room (DR), and minimally invasive surfactant therapy (MIST). Read More

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September 2021

Lung Ultrasound in Bronchopulmonary Dysplasia: Patterns and Predictors in Very Preterm Infants.

Neonatology 2021 Aug 13:1-9. Epub 2021 Aug 13.

Neonatology Department, Hospital Clínic Barcelona, Barcelona Center for Maternal-Fetal and Neonatal Medicine (BCNatal), Barcelona, Spain.

Introduction: Lung ultrasound (LUS) is useful for respiratory management in very preterm infants (VPI), but little is known about the echographic patterns in bronchopulmonary dysplasia (BPD), the relation between the image findings, and the severity of the disease and its long-term outcomes. We aimed to describe LUS patterns in BPD and analyze the accuracy of LUS to predict the need for respiratory support at 36 weeks postmenstrual age (PMA) in VPI.

Methods: Preterm infants ≤30. Read More

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Oxygen Sensing and Signaling in Alzheimer's Disease: A Breathtaking Story!

Cell Mol Neurobiol 2021 Sep 12. Epub 2021 Sep 12.

CNC - Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Rua Larga, Polo I, 1st Floor, 3004-504, Coimbra, Portugal.

Oxygen sensing and homeostasis is indispensable for the maintenance of brain structural and functional integrity. Under low-oxygen tension, the non-diseased brain has the ability to cope with hypoxia by triggering a homeostatic response governed by the highly conserved hypoxia-inducible family (HIF) of transcription factors. With the advent of advanced neuroimaging tools, it is now recognized that cerebral hypoperfusion, and consequently hypoxia, is a consistent feature along the Alzheimer's disease (AD) continuum. Read More

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September 2021

A daily-life study of interpersonal stressors and alcohol use in individuals with borderline personality disorder and community controls.

Drug Alcohol Depend 2021 Sep 4;228:109021. Epub 2021 Sep 4.

Department of Psychological Sciences, University of Missouri, 200 South 7th Street, Columbia, MO, 65211, United States. Electronic address:

Background: Interpersonal stressors (ISs) are major factors in relapse in alcohol use disorder (AUD) and are theorized to play a role in drinking behaviors. Past work has examined this association using ecological momentary assessment (EMA), but the unique effects of rejections and disagreements on alcohol use are unknown. Research suggests the two ISs functionally differ and may display distinct associations with drinking. Read More

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September 2021

Adrenomedullin Deficiency Potentiates Lipopolysaccharide-Induced Experimental Bronchopulmonary Dysplasia in Neonatal Mice.

Am J Pathol 2021 Sep 8. Epub 2021 Sep 8.

Section of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. Electronic address:

Lung inflammation interrupts alveolarization and causes bronchopulmonary dysplasia (BPD). Besides mechanical ventilation and hyperoxia, sepsis contributes to BPD pathogenesis. Adrenomedullin (Adm) is a multifunctional peptide that exerts anti-inflammatory effects in the lungs of adult rodents. Read More

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September 2021

Influence of extreme prematurity and bronchopulmonary dysplasia on cardiac function.

Echocardiography 2021 Sep 9. Epub 2021 Sep 9.

Fetal & Neonatal Cardiology Program, Division of Cardiology, Department of Pediatrics, Stollery Children's Hospital, Edmonton, Alberta, Canada.

Objective: Prematurity and bronchopulmonary dysplasia (BPD) are associated with poorly understood abnormalities of ventricular function. We therefore comprehensively compared biventricular function in infants with and without BPD.

Methods: Prospective observational study in extremely preterm infants with (n = 20) and without (n = 38) BPD using conventional and advanced echocardiography at 28 days (T1) and near-term (T2). Read More

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September 2021

Photodynamic therapy outcome modelling for patients with spinal metastases: a simulation-based study.

Sci Rep 2021 Sep 9;11(1):17871. Epub 2021 Sep 9.

Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada.

Spinal metastases often occur in the advanced stages of breast, lung or prostate cancer, resulting in a significant impact on the patient's quality of life. Current treatment modalities for spinal metastases include both systemic and localized treatments that aim to decrease pain, improve mobility and structural stability, and control tumour growth. With the development of non-toxic photosensitizer drugs, photodynamic therapy (PDT) has shown promise as a minimally invasive non-thermal alternative in oncology, including for spinal metastases. Read More

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September 2021

Plant Flavonoids: Chemical Characteristics and Biological Activity.

Molecules 2021 Sep 4;26(17). Epub 2021 Sep 4.

LAQV/REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.

In recent years, more attention has been paid to natural sources of antioxidants. Flavonoids are natural substances synthesized in several parts of plants that exhibit a high antioxidant capacity. They are a large family, presenting several classes based on their basic structure. Read More

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September 2021

Complicated Intubations are Associated with Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.

Am J Perinatol 2021 Sep 9. Epub 2021 Sep 9.

Department of Pediatrics, Division of Neonatology, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio.

Objective:  This study aimed to evaluate the association between desaturation <60% (severe desaturation) during intubation and a total number of intubation attempts in the first week of life in very low birth weight (VLBW) infants with adverse long-term outcomes including bronchopulmonary dysplasia (BPD) and severe periventricular/intraventricular hemorrhage grade 3 or 4 (PIVH).

Study Design:  A retrospective chart review was performed on VLBW infants intubated in the neonatal intensive care unit during the first week of life between January 2017 and July 2020. Descriptive tables were generated for two outcomes including BPD and PIVH. Read More

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September 2021

Reduced Exercise Capacity in Adults Born Very Low Birth Weight: A Population-Based Cohort Study.

Am J Respir Crit Care Med 2021 Sep 9. Epub 2021 Sep 9.

University of Otago Christchurch, 2494, Department of Pediatrics, Christchurch, New Zealand.

Rationale: Population-based data regarding the consequences of very low birth weight (VLBW) and bronchopulmonary dysplasia (BPD) on adult exercise capacity is limited.

Objectives: To compare exercise capacity in a national VLBW cohort with term-born controls and explore factors contributing to the differences.

Methods: At 26-30 years of age, 228 VLBW survivors and 100 controls underwent lung function tests, cardiopulmonary exercise testing and assessment of resting cardiac structure/function using echocardiography. Read More

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September 2021

Effects of PI3K inhibition in AI-resistant breast cancer cell lines: autophagy, apoptosis, and cell cycle progression.

Breast Cancer Res Treat 2021 Sep 8. Epub 2021 Sep 8.

Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, UCIBIO.REQUIMTE, University of Porto, Rua Jorge Viterbo Ferreira no. 228, 4050-313, Porto, Portugal.

Introduction: Breast cancer is the leading cause of cancer death in women. The aromatase inhibitors (AIs), Anastrozole (Ana), Letrozole (Let), and Exemestane (Exe) are a first-line treatment option for estrogen receptor-positive (ER) breast tumors, in postmenopausal women. Nevertheless, the development of acquired resistance to this therapy is a major drawback. Read More

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September 2021

Development of a Nomogram for Moderate-to-Severe Bronchopulmonary Dysplasia or Death: Role of N-Terminal Pro-brain Natriuretic Peptide as a Biomarker.

Front Pediatr 2021 23;9:727362. Epub 2021 Aug 23.

Neonatal Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

This study aimed to explore the clinical value of N-terminal pro-brain natriuretic peptide (NT-proBNP) in predicting moderate-to-severe bronchopulmonary dysplasia (BPD)/death, and to establish an effective clinical predictive nomogram. We retrospectively analyzed very low birth weight infants (VLBWs) with gestational age ≤ 32 weeks. The NT-proBNP values were determined on the 1st, 3rd, 7th, 14th, 21st, and 28th days after birth. Read More

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