5,003 results match your criteria bone-implant interface


Ligament Balancing and Constraint in Revision Total Knee Arthroplasty.

J Knee Surg 2021 Sep 10. Epub 2021 Sep 10.

Joint Implant Surgeons, Inc, New Albany, Ohio.

Ligament balancing in revision knee arthroplasty is crucial to the success of the procedure. The medial collateral ligament and lateral ligament complex are the primary ligamentous structures that provide stability. Revisions can be performed with nonconstrained cruciate-retaining, posterior cruciate substituting, or anterior-stabilized/ultracongruent inserts when there are symmetrical flexion/extension gaps and intact collateral ligaments. Read More

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September 2021

The effect of humeral implant thickness and canal fill on interface contact and bone stresses in the proximal humerus.

JSES Int 2021 Sep 8;5(5):881-888. Epub 2021 Jul 8.

Roth|McFarlane Hand and Upper Limb Center Biomechanics Laboratory, London, ON, Canada.

Background: Stem size is an important element for successful time zero primary fixation of a press-fit humeral stem in shoulder arthroplasty. Little basic science research, however, has been conducted on the effects of implant thickness and canal fill on load transfer, contact, and stress shielding. The purpose of this finite element study was to determine the effects of varying stem thickness on bone contact, bone stresses, and bone resorption owing to stress shielding. Read More

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September 2021

The role of cortical zone level and prosthetic platform angle in dental implant mechanical response: A 3D finite element analysis.

Dent Mater 2021 Sep 6. Epub 2021 Sep 6.

School of Medical Sciences and Photon Science Institute, University of Manchester, UK.

Objective: The aim of this study was to evaluate the influence of three different dental implant neck geometries, under a combined compressive/shear load using finite element analysis (FEA). The implant neck was positioned in D2 quality bone at the crestal level or 2 mm below.

Methods: One dental implant (4. Read More

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September 2021

Hydroxyapatite-Coated Titanium by Micro-Arc Oxidation and Steam-Hydrothermal Treatment Promotes Osseointegration.

Front Bioeng Biotechnol 2021 19;9:625877. Epub 2021 Aug 19.

Department of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.

Titanium (Ti)-based alloys are widely used in tissue regeneration with advantages of improved biocompatibility, high mechanical strength, corrosion resistance, and cell attachment. To obtain bioactive bone-implant interfaces with enhanced osteogenic capacity, various methods have been developed to modify the surface physicochemical properties of bio-inert Ti and Ti alloys. Nano-structured hydroxyapatite (HA) formed by micro-arc oxidation (MAO) is a synthetic material, which could facilitate osteoconductivity, osteoinductivity, and angiogenesis on the Ti surface. Read More

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Fracture morphology and biomechanical characteristics of Pauwels III femoral neck fractures in young adults.

Injury 2021 Aug 27. Epub 2021 Aug 27.

Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, NO. 600, Yishan Rd., Shanghai, 200233, P.R.China. Electronic address:

Background: Pauwels classification, which categorizes types of femoral neck fractures, cannot fully reflect the three-dimensional characteristics of this injury. The purpose of our study was to determine the morphological characteristics of Pauwels III fractures through computed tomography image analysis and summarize the relevant biomechanical characteristics of different morphological fractures.

Methods: We retrospectively reviewed a total of 209 patients diagnosed with Pauwels type III femoral neck fractures. Read More

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Qualitative predictions of bone growth over optimally designed macro-textured implant surfaces obtained using NN-GA based machine learning framework.

Med Eng Phys 2021 Sep 12;95:64-75. Epub 2021 Aug 12.

Department of Mechanical Engineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781 039, India.

The surface features on implant surface can improve biologic fixation of the implant with the host bone leading to improved secondary (biological) implant stability. Application of finite element (FE) based mechanoregulatory schemes to estimate the amount of bone growth for a wide range of implant surface features is either manually intensive or computationally expensive. This study adopts an integrated approach combining FE, back-propagation neural network (BPNN) and genetic algorithm (GA) based search to evaluate optimum surface macro-textures from three representative implant models so as to enhance bone growth. Read More

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September 2021

Tibial tray debonding from the cement mantle is associated with deformation of the backside of polyethylene tibial inserts.

Bone Joint J 2021 Sep 3:1-11. Epub 2021 Sep 3.

ExplantLab, Newcastle Upon Tyne, UK.

Aims: The aim of this study was to investigate whether wear and backside deformation of polyethylene (PE) tibial inserts may influence the cement cover of tibial trays of explanted total knee arthroplasties (TKAs).

Methods: At our retrieval centre, we measured changes in the wear and deformation of PE inserts using coordinate measuring machines and light microscopy. The amount of cement cover on the backside of tibial trays was quantified as a percentage of the total surface. Read More

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September 2021

Load applied on osseointegrated implant by transfemoral bone-anchored prostheses fitted with state-of-the-art prosthetic components.

Clin Biomech (Bristol, Avon) 2021 Aug 24;89:105457. Epub 2021 Aug 24.

ÖSSUR, R&D, Medical Office, Grjothals 1-5, Reykjavik, Iceland.

Background: This study presented the load profile applied on transfemoral osseointegrated implants by bone-anchored prostheses fitted with state-of-the-art ÖSSUR microprocessor-controlled Rheo Knee XC and energy-storing-and-returning Pro-Flex XC or LP feet during five standardized daily activities.

Methods: This cross-sectional cohort study included 13 participants fitted with a press-fit transfemoral osseointegrated implant. Loading data were directly measured with the tri-axial transducer of an iPecsLab (RTC Electronics, USA) fitted between the implant and knee unit. Read More

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Protein adsorption/desorption dynamics on Ca-enriched titanium surfaces: biological implications.

J Biol Inorg Chem 2021 Sep 27;26(6):715-726. Epub 2021 Aug 27.

Department of Industrial Systems Engineering and Design, Universitat Jaume I, Campus del Ríu Sec, Av. Vicent Sos Baynat s/n, 12071, Castellón de la Plana, Spain.

Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant surfaces modifies the physicochemical characteristics at the implant-tissue interface and thus, the biological responses. The aim of this study is to examine how the dynamics of protein adsorption on these surfaces change over time. Read More

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September 2021

Analysis of Surface Morphology and Elemental Composition on Zirconia Implants Before and After Photofunctionalization by Scanning Electron Microscopy and Energy Dispersive X ray Spectroscopy - An Study.

J Pharm Bioallied Sci 2021 Jun 5;13(Suppl 1):S761-S765. Epub 2021 Jun 5.

Oral Medicine and Radiology, Best Dental Science College, Madurai, Tamil Nadu, India.

Background: The purpose of this study is to analyze the surface morphology and elemental composition of zirconia implants before and after photofunctionalization.

Materials And Methods: Ten zirconia implants (white sky implant system- Bredent Company) five each in the study group and control group was taken. Study group samples were treated with ultraviolet light for 48 h. Read More

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Stress Distribution in Cortical Bone around the Basal Implant - A Finite Element Analysis.

J Pharm Bioallied Sci 2021 Jun 5;13(Suppl 1):S633-S636. Epub 2021 Jun 5.

Consultant Prosthodontist, Katihar, Bihar, India.

Aim: The aim of the study was to develop a model that represents a basal implant with stress distribution in the cortical bone on application of loads emulating masticatory forces.

Materials And Methods: In this study, the stress distribution in the bone and the implant is evaluated by applying various loads that emulate the masticatory forces. The geometric models of cortical bone representing the premolar area and a basal implant model of the following specifications, longitudinal oval threaded pin (1. Read More

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Mechanical Properties of Porous Structures for Dental Implants: Experimental Study and Computational Homogenization.

Materials (Basel) 2021 Aug 16;14(16). Epub 2021 Aug 16.

High Technical School of Architecture, University of Seville, 41012 Sevilla, Spain.

A combined experimental and numerical study on titanium porous microstructures intended to interface the bone tissue and the solid homogeneous part of a modern dental implant is presented. A specific class of trabecular geometries is compared to a gyroid structure. Limitations associated with the application of the adopted selective laser melting technology to small microstructures with a pore size of 500 μm are first examined experimentally. Read More

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Sustainable Surface Modification of Polyetheretherketone (PEEK) Implants by Hydroxyapatite/Silica Coating-An In Vivo Animal Study.

Materials (Basel) 2021 Aug 16;14(16). Epub 2021 Aug 16.

Department of Oral, Maxillofacial and Plastic Surgery, Rostock University Medical Center, 18057 Rostock, Germany.

Polyetheretherketone (PEEK) has the potential to overcome some of the disadvantages of titanium interbody implants in anterior cervical and discectomy and fusion (ACDF). However, PEEK shows an inferior biological behavior regarding osseointegration and bioactivity. Therefore, the aim of the study was to create a bioactive surface coating on PEEK implants with a unique nanopore structure enabling the generation of a long-lasting interfacial composite layer between coating material and implant. Read More

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Bone Response to Conventional Titanium Implants and New Zirconia Implants Produced by Additive Manufacturing.

Materials (Basel) 2021 Aug 6;14(16). Epub 2021 Aug 6.

Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea.

The aim of the present study was to evaluate the in vivo bone response to an additively manufactured zirconia surface compared to osseointegration into titanium (Ti) surfaces. Scanning electron microscopy, confocal laser scanning microscopy, and electron spectroscopy for chemical analysis were performed to assess the surface characteristics of implant specimens. For the in vivo evaluation, eight Ti implants and eight 3D-printed zirconia implants were used. Read More

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Long-Term Outcomes of Radial Head Arthroplasty in Complex Elbow Fracture Dislocation.

J Clin Med 2021 Aug 7;10(16). Epub 2021 Aug 7.

Bone and Joint Research Center, Department of Orthopaedic Surgery, Chang Gung Memorial Hospital-Linkou, Taoyuan 333, Taiwan.

The purpose of the current study was to investigate the long-term outcomes of radial head arthroplasty in complex elbow injuries through radiographic analysis and functional correlation. We evaluated 24 radial head arthroplasties in 24 consecutive patients with complex elbow fracture dislocation. All patients were treated with a single type of modular monopolar prosthesis containing smooth stem in press-fit implantation. Read More

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Influences of screw design features on initial stability in immediate implant placement and restoration.

Clin Biomech (Bristol, Avon) 2021 Aug 20;89:105453. Epub 2021 Aug 20.

School of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address:

Background: Self-tapping screws have been extensively used for dental implants. Their biomechanical behavior is highly associated with their clinical success, particularly for screws used for immediate implant placement and restoration, because occlusal forces can directly affect the loading transfer at the bone-implant interface after implantation. The effect of implant design on the initial stability of self-tapping screws remains unclear. Read More

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Validation of a 3D CT imaging method for quantifying implant migration following anatomic total shoulder arthroplasty.

J Orthop Res 2021 Aug 26. Epub 2021 Aug 26.

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA.

Glenoid component loosening remains a common complication following anatomic total shoulder arthroplasty (TSA); however, plain radiographs are unable to accurately detect early implant migration. The purpose of this study was to validate the accuracy of a method of postoperative, three-dimensional (3D) computed tomography (CT) imaging with metal artifact reduction (MAR) to detect glenoid component migration following anatomic TSA. Tantalum bead markers were inserted into polyethylene glenoid components for implant detection on 3D CT. Read More

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Effect of systemic administration of omeprazole on osseointegration around titanium dental implants: A histomorphometric study in dogs.

Dent Res J (Isfahan) 2021 22;18:43. Epub 2021 Jun 22.

Department of Periodontology, Dental Implant Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Dental implants are widely accepted substitutes for replacing missing teeth. Many factors, including the use of specific drugs such as proton-pump inhibitors (PPIs) (omeprazole), can affect the success of dental implantations. The aim of this study was to investigate the relationship between the use of omeprazole and osseointegration of dental implants. Read More

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Influence of the geometry of the screwdriver-screw connection on the reverse torque of UCLA screws.

Gen Dent 2021 Sep-Oct;69(5):62-66

The aim of this study was to evaluate the influence of the geometry of the screwdriver-screw connection on the reverse torque of UCLA screws after repeated cycles of tightening and loosening in an implant-supported prosthesis. Thirty sets of external hex titanium implants, UCLA abutments, and UCLA abutment screws were divided into 3 experimental groups (n = 10). In the square group, the implant and UCLA abutment system were mounted in an upright position using a screw with a square screwdriver-screw connection. Read More

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The effect of a novel pillar surface morphology and material composition demonstrates uniform osseointegration.

J Mech Behav Biomed Mater 2021 Nov 14;123:104775. Epub 2021 Aug 14.

The University of New South Wales, Australia.

Long-term survival of orthopedic implants requires a strong and compliant interface between the implant and surrounding bone. This paper further explores the in-vivo response to a novel, macro-scale osseointegration surface morphology. In this study, we examine the effects of material composition on osseointegration in relation to the controlled surface geometry. Read More

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November 2021

The effect of implant-abutment connections on peri-implant bone levels around single implants in the aesthetic zone: A systematic review and a meta-analysis.

Clin Exp Dent Res 2021 Aug 21. Epub 2021 Aug 21.

Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

Objective: To systematically review literature about the effect of different implant-abutment interface designs on peri-implant bone level changes, implant loss and mid-buccal mucosa changes around single implants in the anterior maxilla. Reviewing three connection configurations: Platform switched conical (PS-conical); Platform switched parallel (PS-parallel); Platform matched parallel (PM-parallel).

Methods: A detailed search was carried out in Pubmed, EMBASE, Cochrane, Scopus, Open Gray and African journals Online (until December 1, 2020) and was restricted to clinical prospective studies of at least 1 year and with at least 10 human participants. Read More

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Biomechanical Analysis of Functionally Graded Root Analog Implants on Alveolar Bone: A 3D Finite Element Study.

Int J Oral Maxillofac Implants 2021 Jul-Aug;36(4):e63-e71

Purpose: This study aimed to investigate whether axial or radial functionally graded root analog implants can optimize the stress and strain distribution near the implant-bone interface in alveolar bone models under static loads using finite element analysis (FEA).

Materials And Methods: The 3D profile of the root analog implant was captured from a natural tooth in CBCT data. The implant was separated into different layers (3, 5, and 10 layers) to vary the Young modulus axially or radially. Read More

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[ study of liposome-modified polyetheretherketone implant on bacteriostasis and osseointegration].

Beijing Da Xue Xue Bao Yi Xue Ban 2021 Aug;53(4):758-763

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing 100081, China.

Objective: To develop dexamethasone plus minocycline-loaded liposomes (Dex/Mino liposomes) and apply them to improve bioinert polyetheretherketone (PEEK) surface, which could prevent post-operative bacterial contamination, enhance ossification for physiologic osseointegration, and finally reduce implant failure rates.

Methods: Dex/Mino liposomes were covalently grafted onto the PEEK surface using polydopamine (pDA) coating as a medium. Confocal laser scanning microscopy was used to confirm the binding of fluorescently labeled liposomes onto the PEEK substrate, and a microplate reader was used to semiquantitatively measure the average fluorescence intensity of fluorescently labeled liposome-decorated PEEK surfaces. Read More

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Temporal response of an injectable calcium phosphate material in a critical size defect.

J Orthop Surg Res 2021 Aug 13;16(1):496. Epub 2021 Aug 13.

Vertex Pharmaceuticals, 50 Northern Ave, Boston, MA, 02210, USA.

Background: Calcium phosphate-based bone graft substitutes are used to facilitate healing in bony defects caused by trauma or created during surgery. Here, we present an injectable calcium phosphate-based bone void filler that has been purposefully formulated with hyaluronic acid to offer a longer working time for ease of injection into bony defects that are difficult to access during minimally invasive surgery.

Methods: The bone substitute material deliverability and physical properties were characterized, and in vivo response was evaluated in a critical size distal femur defect in skeletally mature rabbits to 26 weeks. Read More

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Novel and simplified optimisation pathway using response surface and design of experiments methodologies for dental implants based on the stress of the cortical bone.

Proc Inst Mech Eng H 2021 Aug 12:9544119211025375. Epub 2021 Aug 12.

Centre for Simulation in Bioengineering, Biomechanics and Biomaterials (CS3B), Department of Mechanical Engineering, Engineering College of Bauru (FEB), São Paulo State University (UNESP), Bauru, São Paulo State, Brazil.

Dental implants are widely used as a long-term treatment solution for missing teeth. A titanium implant is inserted into the jawbone, acting as a replacement for the lost tooth root and can then support a denture, crown or bridge. This allows discreet and high-quality aesthetic and functional improvement, boosting patient confidence. Read More

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A single application of chlorhexidine gel reduces gingival inflammation and interleukin 1-β following one-stage implant placement: A randomized controlled study.

Clin Implant Dent Relat Res 2021 Aug 11. Epub 2021 Aug 11.

Department of Periodontology, Rambam Health Care Campus, Haifa, Israel.

Background: Chlorhexidine (CHX) is a broad-spectrum antimicrobial agent commonly used in medicine. Application of (CHX) during abutment connection reduced the bacterial load at the implant-abutment interface. We hypothesize this treatment may consequently reduce peri-implant soft tissue inflammation and marginal bone loss. Read More

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Molecular-Level Understanding of the Influence of Ions and Water on HMGB1 Adsorption Induced by Surface Hydroxylation of Titanium Implants.

Langmuir 2021 08 9;37(33):10100-10114. Epub 2021 Aug 9.

Department of Chemistry and Biochemistry, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States.

Due to its excellent chemical and mechanical properties, titanium has become the material of choice for orthopedic and dental implants to promote rehabilitation via bone anchorage and osseointegration. Titanium osseointegration is partially related to its capability to form a TiO surface layer and its ability to interact with key endogenous proteins immediately upon implantation, establishing the first bone-biomaterial interface. Surgical trauma caused by implantation results in the release of high-mobility group box 1 (HMGB1) protein, which is a prototypic DAMP (damage-associated molecular pattern) with multiple roles in inflammation and tissue healing. Read More

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Is three-dimensional-printed custom-made ultra-short stem with a porous structure an acceptable reconstructive alternative in peri-knee metaphysis for the tumorous bone defect?

World J Surg Oncol 2021 Aug 8;19(1):235. Epub 2021 Aug 8.

Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, People's Republic of China.

Background: Long-lasting reconstruction after extensive resection involving peri-knee metaphysis is a challenging problem in orthopedic oncology. Various reconstruction methods have been proposed, but they are characterized by a high complication rate. The purposes of this study were to (1) assess osseointegration at the bone implant interface and correlated incidence of aseptic loosening; (2) identify complications including infection, endoprosthesis fracture, periprosthetic fracture, leg length discrepancy, and wound healing problem in this case series; and (3) evaluate the short-term function of the patient who received this personalized reconstruction system. Read More

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Habitual caffeine intake affects implant osseointegration: An in vivo study.

J Periodontal Res 2021 Aug 7. Epub 2021 Aug 7.

Department of Substitutive Dental Science, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Objectives: This study aimed to evaluate the effect of habitual caffeine (CAF) intake on stability, bone regeneration, and expression of bone markers at the bone-implant interface.

Background: Studies show that habitual CAF alters bone health and remodeling. Yet, there is no information regarding CAF effects on osseointegration of bone-anchored implants. Read More

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Periprosthetic Stress Shielding of the Humerus after Reconstruction with Modular Shoulder Megaprostheses in Patients with Sarcoma.

J Clin Med 2021 Jul 31;10(15). Epub 2021 Jul 31.

Department of Orthopedics and Tumor Orthopedics, University Hospital Muenster, 48149 Münster, Germany.

(1) Background: Modular megaprosthetic reconstruction using a proximal humerus replacement has emerged as a commonly chosen approach after bone tumor resection. However, the long-term risk for revision surgery is relatively high. One factor that might be associated with mechanical failures is periprosthetic osteolysis around the stem, also known as stress shielding. Read More

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