2,910 results match your criteria body functionality


The multifaceted roles of macrophages in bone regeneration: A story of polarization, activation and time.

Acta Biomater 2021 May 8. Epub 2021 May 8.

Julius Wolff Institut, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

To present knowledge, macrophages are found in all tissues of the human body. They are a cell population with high plasticity which come with a multitude of functions which appear to be adapted to the respective tissue niche and micro-environment in which they reside. Bone harbors multiple macrophage subpopulations, with the osteoclasts as classical representative of a bone resorbing cells and osteomacs as a bone tissue resident macrophage first described by the expression of F4/80. Read More

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Investigation of the , and Mutations and Polymorphisms in Iranian Infertile Women with Polycystic Ovary Syndrome (PCOS).

Rep Biochem Mol Biol 2021 Jan;9(4):470-477

Vali-e-Asr Reproductive Health Research center, Tehran University of Medical Sciences, Tehran, Iran.

Background: Polycystic ovary syndrome (PCOS) is the most common cause of ovarian dysfunction associated with infertility, Oligomenorrhea or amenorrhea, hirsutism, acne, and obesity. A large body of evidence unraveled, three major groups of genes play critical roles in underlying PCOS molecular mechanism. The aim of this study is to investigate critical exonic variant of , and and determine the functionality of these mutations in Iranian patients with PCOS. Read More

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January 2021

Green and clean modification of cassava starch - effects on composition, structure, properties and digestibility.

Crit Rev Food Sci Nutr 2021 May 8:1-27. Epub 2021 May 8.

Biosciences and Food Technology, School of Science, RMIT University, Melbourne, VIC, Australia.

There is a growing need for clean and green labeling of food products among consumers globally. Therefore, development of green modified starches, to boost functionality, palatability and health benefits while reducing the negative processing impacts on the environment and reinforcing consumer safety is in high demand. Starch modification started in mid-1500s due to the inherent limitations of native starch restricting its commercial applications, with chemical modification being most common. Read More

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Application of a sub-0.1-mm implantable mote for in vivo real-time wireless temperature sensing.

Sci Adv 2021 May 7;7(19). Epub 2021 May 7.

Department of Electrical Engineering, Columbia University, New York, NY 10027, USA.

There has been increasing interest in wireless, miniaturized implantable medical devices for in vivo and in situ physiological monitoring. Here, we present such an implant that uses a conventional ultrasound imager for wireless powering and data communication and acts as a probe for real-time temperature sensing, including the monitoring of body temperature and temperature changes resulting from therapeutic application of ultrasound. The sub-0. Read More

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Behavioural and Emotional Symptoms of Adolescents Consulting a Specialised Eating Disorders Programme.

Rev Colomb Psiquiatr 2021 May 4. Epub 2021 May 4.

Especialista en psiquiatría infantil y del adolescente, Docente de psiquiatría de la Universidad El Bosque, Bogotá, Colombia.

Introduction: Eating disorders (EDs) are complex conditions of multifactorial origin. Their main characteristic is excessive concern about body weight and shape, which causes great discomfort and physical problems and leads to a decrease in quality of life and alterations in the patient's functionality social environment. The objective of this study is to describe the emotional and behavioural symptoms of adolescents who consult a specialised ED programme in the city of Bogota. Read More

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Psychometric properties of an Italian translation of the Functionality Appreciation Scale (FAS).

Body Image 2021 May 4;38:210-218. Epub 2021 May 4.

School of Psychology and Sport Science, Anglia Ruskin University, Cambridge, United Kingdom; Centre for Psychological Medicine, Perdana University, Kuala Lumpur, Malaysia.

The Functionality Appreciation Scale (FAS; Alleva et al., 2017) is a widely used instrument for the measurement of individual's appreciation of their body for what it can do and is capable of doing (i.e. Read More

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Amine-functionalized carbon-fiber microelectrodes for enhanced ATP detection with fast-scan cyclic voltammetry.

Anal Methods 2021 May 7. Epub 2021 May 7.

Department of Chemistry, University of Cincinnati, 312 College Dr., 404 Crosley Tower, Cincinnati, OH 45221-0172, USA.

Here, we provide evidence that functionalizing the carbon-fiber surface with amines significantly improves direct electrochemical adenosine triphosphate (ATP) detection with fast-scan cyclic voltammetry (FSCV). ATP is an important extracellular signaling molecule throughout the body and can function as a neurotransmitter in the brain. Several methods have been developed over the years to monitor and quantitate ATP signaling in cells and tissues; however, many of them are limited in temporal resolution or are not capable of measuring ATP directly. Read More

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Compositional and functional properties of milk and dairy products derived from cows fed pasture or concentrate-based diets.

Compr Rev Food Sci Food Saf 2021 May 5. Epub 2021 May 5.

Food Chemistry and Technology, Teagasc Food Research Centre, Cork, Ireland.

Worldwide milk production is predominantly founded on indoor, high-concentrate feeding systems, whereas pasture-based feeding systems are most common in New Zealand and Ireland but have received greater attention recently in countries utilizing conventional systems. Consumer interest in 'pasture-fed' dairy products has also increased, arising from environmental, ethical, and nutritional concerns. A substantial body of research exists describing the effect of different feeding strategies on the composition of milk, with several recent studies focusing on the comparison of pasture- and concentrate-based feeding regimes. Read More

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Maternal exercise during pregnancy modulates mitochondrial function and redox status in a sex-dependent way in adult offspring's skeletal muscle.

J Dev Orig Health Dis 2021 May 5:1-8. Epub 2021 May 5.

Programa de Pós-Graduação em Ciências Biológicas - Bioquímica, Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Maternal exercise has shown beneficial effects on mother and child. Literature confirm progeny's cognition improvement, and upregulation in neurotrophins, antioxidant network, and DNA repair system. Considering that there is a lack of information demonstrating the impact of maternal exercise on offspring's skeletal muscle, we aimed to investigate the mitochondrial and redox effects elicited by maternal swimming. Read More

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Associations of sarcopenic obesity versus sarcopenia alone with functionality.

Clin Nutr 2021 Apr 12;40(5):2851-2859. Epub 2021 Apr 12.

Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Capa, 34390, Istanbul, Turkey.

Background & Aims: There have been several attempts to come up with a global operational definition of sarcopenia (S), and consequently, a definition of S has been established, to some extent. That said, the definition of sarcopenic obesity (SO), which is defined as the presence of obesity + sarcopenia, remains obscure, hindering evaluations of the prevalence and relevance of SO. It has yet to be elucidated whether SO is associated with worse functionality when compared to S alone (S without obesity). Read More

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Electronic Drugs: Spatial and Temporal Medical Treatment of Human Diseases.

Adv Mater 2021 May 2:e2005930. Epub 2021 May 2.

Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Recent advances in diagnostics and medicines emphasize the spatial and temporal aspects of monitoring and treating diseases. However, conventional therapeutics, including oral administration and injection, have difficulties meeting these aspects due to physiological and technological limitations, such as long-term implantation and a narrow therapeutic window. As an innovative approach to overcome these limitations, electronic devices known as electronic drugs (e-drugs) have been developed to monitor real-time body signals and deliver specific treatments to targeted tissues or organs. Read More

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Breastfeeding, body image, and weight control behavior among postpartum women.

Body Image 2021 Apr 29;38:201-209. Epub 2021 Apr 29.

Rutgers University, USA. Electronic address:

The goal of this study was to examine breastfeeding behavior and attitudes as predictors of women's body image and weight control behavior. This study extends past research by focusing on positive body image variables including body appreciation and perceived body functionality. Women (N = 597) from the United States who had recently birthed biological babies ages 0-12 months participated in an online study. Read More

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Variants That Differentiate Wolf and Dog Populations Are Enriched in Regulatory Elements.

Genome Biol Evol 2021 Apr;13(4)

KTH Royal Institute of Technology, School of Chemistry, Biotechnology and Health, Science for Life Laboratory, Stockholm, Sweden.

Research on the genetics of domestication most often focuses on the protein-coding exons. However, exons cover only a minor part (1-2%) of the canine genome, whereas functional mutations may be located also in regions beyond the exome, in regulatory regions. Therefore, a large proportion of phenotypical differences between dogs and wolves may remain genetically unexplained. Read More

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Pharmacokinetics of Selinexor: The First-in-Class Selective Inhibitor of Nuclear Export.

Clin Pharmacokinet 2021 Apr 29. Epub 2021 Apr 29.

Karyopharm Therapeutics, 85 Wells Ave, Newton, MA, 02459, USA.

The functionality of many tumor suppressor proteins (TSPs) and oncoprotein transcript RNAs largely depend on their location within the cell. The exportin 1 complex (XPO1) transports many of these molecules from the nucleus into the cytoplasm, thereby inactivating TSPs and activating oncoprotein transcript RNAs. Aberrations of these molecules or XPO1 can increase this translocation process, leading to oncogenesis. Read More

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Validation of Antiobesity Effects of Black Soybean Seed Coat Powder Suitable as a Food Material: Comparisons with Conventional Yellow Soybean Seed Coat Powder.

Foods 2021 Apr 13;10(4). Epub 2021 Apr 13.

Department of Applied Biological Chemistry, Graduate School of Agriculture, Kindai University, 3327-204 Naka-machi, Nara 631-8505, Japan.

In this study, we fed obese model mice black soybean seed coat powder (BSCP) and evaluated the antiobesity effects. As a control, normal yellow soybean seed coat powder (YSCP) was used. C57BL/6J, a high-fat diet-induced obesity model mouse, was fed a high-fat diet containing BSCP or YSCP (20% fat) to induce obesity. Read More

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In Vivo Evaluation of Leaf Extract for Anti-Obesity and Cholesterol-Lowering Activity in Mice.

Nutrients 2021 Apr 23;13(5). Epub 2021 Apr 23.

Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

Metabolic syndrome is a worldwide health problem, and obesity is closely related to type 2 diabetes, cardiovascular disease, hypertension, and cancer. According to WHO in 2018, the prevalence of obesity in 2016 tripled compared to 1975. reduces bad cholesterol and triglycerides levels in the blood and provides various antioxidant nutrients and germicidal sub-stances, as well as selenium, which helps to remove active oxygen. Read More

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Phase Angle Is Related to 10 m and 30 m Sprint Time and Repeated-Sprint Ability in Young Male Soccer Players.

Int J Environ Res Public Health 2021 Apr 21;18(9). Epub 2021 Apr 21.

Institute of Physical Education and Sport, Federal University of Alagoas, Maceió 57072-900, AL, Brazil.

Objective: To examine the association between phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) and components of physical performance in male youth soccer players.

Design: Cross-sectional.

Methods: Sixty-two players from two professional soccer academies were recruited. Read More

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Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human.

Cell Discov 2020 Apr 28;6(1):22. Epub 2020 Apr 28.

Institute of Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, 518112, China.

The liver plays a critical role in both immune defense and tolerance in the body. The liver-resident immune cells (LrICs) determine the immune properties, but the unique composition and heterogeneity of these cells are incompletely understood. Here, we dissect the diversity of LrICs by a comprehensive transcriptomic profiling using the unbiased single-cell RNA-sequencing (scRNA-seq). Read More

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Effect of overconditioning on the hepatic global gene expression pattern of dairy cows at the end of pregnancy.

J Dairy Sci 2021 Apr 22. Epub 2021 Apr 22.

Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium.

Overconditioning is a risk factor for upregulated pre- and postpartum fat mobilization. Therefore, we hypothesized that overconditioning at the end of pregnancy leads to the accumulation of lipids in the liver and modifications of the hepatic gene expression pattern. The aim of this study was to evaluate the effect of normal- versus overconditioning on the hepatic transcriptomic profile of dairy cows at the end of pregnancy. Read More

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Experiences of Pregnant Women With Obesity.

Nurs Womens Health 2021 Apr 22. Epub 2021 Apr 22.

Objective: To explore how pregnant women with obesity feel about their bodies before and during pregnancy.

Design: Qualitative descriptive design.

Setting: Obstetric and gynecologic offices in a rural setting in Maryland that employed physicians and midwives as prenatal care providers. Read More

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Burn Specific Health Scale - Brief - Brazil and International Classification of Functioning, Disability and Health in burn patients.

J Burn Care Res 2021 Apr 23. Epub 2021 Apr 23.

Discipline of Plastic Surgery, Surgery Department, (UNIFESP/EPM), Brazil.

With better burn trauma survival rates, quality of life and functionality have become important outcomes in the evaluation of burn patients.The objective of this study was to evaluate the quality of life of burn survivors using the Burn Specific Health Scale-Brief-Br and their function and health using the International Classification of Functioning Disability and Health (ICF) in order to assess whether there is a correlation in the results obtained between the two instruments. A cross-sectional study with 80 burn patients who underwent outpatient follow-up was completed. Read More

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Vividness of Visual Imagery and Personality Impact Motor-Imagery Brain Computer Interfaces.

Front Hum Neurosci 2021 6;15:634748. Epub 2021 Apr 6.

Department of Cognitive Science and Artificial Intelligence, Tilburg University, Tilburg, Netherlands.

Brain-computer interfaces (BCIs) are communication bridges between a human brain and external world, enabling humans to interact with their environment without muscle intervention. Their functionality, therefore, depends on both the BCI system and the cognitive capacities of the user. Motor-imagery BCIs (MI-BCI) rely on the users' mental imagination of body movements. Read More

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Effect of an education and mindfulness-based physical activity intervention for the promotion of positive body image in Lithuanian female students.

Eat Weight Disord 2021 Apr 20. Epub 2021 Apr 20.

Department of Physical and Social Education, Lithuanian Sports University, Sporto 6, 44221, Kaunas, Lithuania.

Purpose: The aim of this study was to test the effectiveness of an 8-week classroom education and mindfulness-based physical activity intervention for the promotion of positive body image in female students.

Methods: A quasi-experimental study was carried out with 110 Lithuanian female students (mean age 21.5 ± 3. Read More

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Identifying and classifying macroinvertebrate indicator signature traits and ecological preferences along urban pollution gradient in the Niger Delta.

Environ Pollut 2021 Apr 9;281:117076. Epub 2021 Apr 9.

Department of Animal Biology (Applied Hydrobiology and Ecotoxicology Unit), Federal University of Technology, Minna, Nigeria. Electronic address:

Urbanisation of riverine landscape is an increasing threat to the functionality of river ecosystems. In this study, we identify and classify macroinvertebrates indicator signature traits and ecological preferences.We hypothesised that urban pollution would differentially influence the distribution of macroinvertebrate traits and ecological preferences along a gradient of water quality deterioration. Read More

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Assessment of Upper-extremity Joint Angles using Harmony Exoskeleton.

IEEE Trans Neural Syst Rehabil Eng 2021 Apr 19;PP. Epub 2021 Apr 19.

The biomechanical complexity of the human shoulder, while critical for functionality, poses a challenge for objective assessment during sensorimotor rehabilitation. With built-in sensing capabilities, robotic exoskeletons have the potential to serve as tools for both intervention and assessment. The bilateral upper-extremity Harmony exoskeleton is capable of full shoulder articulation, forearm flexion-extension, and wrist pronation-supination motions. Read More

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Evidence Based Position Paper on Physical and Rehabilitation Medicine professional practice for persons with cerebral palsy.

Eur J Phys Rehabil Med 2021 Apr 16. Epub 2021 Apr 16.

Spinal Unit, Montecatone Rehabilitation Institute, Imola Bologna, Italy.

Introduction: Cerebral palsy (CP) is a group of the most common developmental disorders affecting movement and posture of the body, causing activity limitations and participation restrictions. The motor disorders of persons with CP are often accompanied by disturbances of sensation, cognition, communication and perception. The symptoms of CP are very diverse and persons with CP are usually presented with a mixed type of symptoms. Read More

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Diabetic kidney disease alters the transcriptome and function of human adipose-derived mesenchymal stromal cells but maintains immunomodulatory and paracrine activities important for renal repair.

Diabetes 2021 Apr 15. Epub 2021 Apr 15.

Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA.

Mesenchymal stem/stromal cells (MSC) facilitate repair in experimental diabetic kidney disease (DKD). However, the hyperglycemic and uremic milieu may diminish regenerative capacity of patient-derived therapy. We hypothesized that DKD reduces human MSC paracrine function. Read More

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Subterahertz collective dynamics of polar vortices.

Nature 2021 Apr 14;592(7854):376-380. Epub 2021 Apr 14.

Advanced Photon Source, Argonne National Laboratory, Lemont, IL, USA.

The collective dynamics of topological structures are of interest from both fundamental and applied perspectives. For example, studies of dynamical properties of magnetic vortices and skyrmions have not only deepened our understanding of many-body physics but also offered potential applications in data processing and storage. Topological structures constructed from electrical polarization, rather than electron spin, have recently been realized in ferroelectric superlattices, and these are promising for ultrafast electric-field control of topological orders. Read More

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ARTICLE: Evolution of Skin Barrier Science for Healthy and Compromised Skin.

J Drugs Dermatol 2021 Apr;20(4):s3-s9

Skin is a complex organ comprised of multiple cell types and microstructures that work in concert to serve critical functions and support the body’s homeostasis. It is the outermost, cornified layer of our body that is primarily responsible for the permeability barrier, protecting against external aggressors and preventing water loss from within. The understanding of the organization, functionality, and underlying mechanisms of the skin barrier has evolved greatly through the years. Read More

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