Search Our Scientific Publications & Authors

Biomaterials 2021 Mar 26;272:120772. Epub 2021 Mar 26.

Institute of Analytical Chemistry, Department of Chemistry, Zhejiang University, Hangzhou, 310058, China. Electronic address:

Insufficient angiogenesis happened in body defects such as ulceration, coronary heart disease, and chronic wounds constitutes a major challenge in tissue regeneration engineering. Owing to the poor bioactivity and maintenance of pro-angiogenic cells and factors during transplantation, new bioactive materials to tackle the barrier are highly desirable. Herein, we demonstrate a co-delivery platform for synergistic promotion of angiogenesis based on biodegradable, therapeutic, and self-reporting luminescent porous silicon (PSi) microparticles. Read More

Exp Gerontol 2021 Apr 7:111346. Epub 2021 Apr 7.

Interdisciplinary Program in Neuroscience, Aysel Sabuncu Brain Research Center, Bilkent University, Ankara, Turkey; National Nanotechnology Research Center (UNAM), Bilkent University, Ankara, Turkey; Department of Molecular Biology and Genetics, Zebrafish Facility, Bilkent University, Ankara, Turkey; Department of Psychology, Bilkent University, Ankara, Turkey. Electronic address:

Progression of cognitive decline with or without neurodegeneration varies among elderly subjects. The main aim of the current study was to illuminate the molecular mechanisms that promote and retain successful aging in the context of factors such as environment and gender, both of which alter the resilience of the aging brain. Environmental enrichment (EE) is one intervention that may lead to the maintenance of cognitive processing at older ages in both humans and animal subjects. Read More

J Am Geriatr Soc 2021 Apr 10. Epub 2021 Apr 10.

Section of Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States.

Background: Older patients with acute decompensated heart failure (ADHF) have severely impaired physical function (PF) and quality of life (QOL). However, relationships between impairments in PF and QOL are unknown but are relevant to clinical practice and trial design.

Methods: We assessed 202 consecutive patients hospitalized with ADHF in the multicenter Rehabilitation Therapy in Older Acute HF Patients (REHAB-HF) Trial. Read More

Curr Genet 2021 Apr 10. Epub 2021 Apr 10.

Department of Sciences, Faculty of Science and Technology, Suan Sunandha Rajabhat University, Bangkok, 10300, Thailand.

A growing body of evidence suggests that Nod Factors molecules are the critical structural components in nitrogen fixation. These molecules have been implicated in plant-microbe signaling. Many enzymes involved in Nod factors biosynthesis; however, the enzymes that decorate (modify) nod factor main structure play a vital role. Read More

Enzymes 2020 8;48:149-173. Epub 2020 Sep 8.

Medicinal Bioconvergence Research Center, College of Pharmacy & School of Medicine, Yonsei University, Incheon, South Korea. Electronic address:

Human body is a finely-tuned machine that requires homeostatic balance based on systemically controlled biological processes involving DNA replication, transcription, translation, and energy metabolism. Ubiquitously expressed aminoacyl-tRNA synthetases have been investigated for many decades, and they act as cross-over mediators of important biological processes. In particular, a cytoplasmic multi-tRNA synthetase complex (MSC) appears to be a central machinery controlling the complexity of biological systems. Read More

J Anim Ecol 2021 Apr 10. Epub 2021 Apr 10.

Department of Integrative Biology, University of Guelph, Guelph, ON, Canada, N1G 2W1.

1. Neonicotinoid insecticides are the most widely used class of insecticides in the world and can have both lethal and sub-lethal effects on non-target organisms in agricultural areas. Monarch butterflies (Danaus plexippus) have experienced dramatic declines in recent decades and, given that a large proportion of milkweed on the landscape grows in agricultural areas, there is concern about the negative effects of neonicotinoids on this non-target insect. Read More

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Department of Surgery, Division of Vascular & Endovascular Surgery, Stanford University School of Medicine, Stanford, CA.

Objectives: Iliac branch devices (IBDs) are modular, bifurcated endografts designed to preserve hypogastric flow during endovascular aortoiliac aneurysm repair. We report our single center outcomes, and describe the unique complications of these devices: inability to cannulate the hypogastric artery (technical failure), occlusion of the internal branch, and type III endoleak from separation of components between the main body and IBD.

Methods: A prospectively maintained institutional database of patients undergoing IBD implantation between 2014 and 2019 was reviewed. Read More

J Gerontol A Biol Sci Med Sci 2021 Apr 9. Epub 2021 Apr 9.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.

Background: Body composition assessment by computed tomography (CT) predicts health outcomes in diverse populations. However, its performance in predicting mortality has not been directly compared to dual-energy-X-ray-absorptiometry (DXA). Additionally, the association between different body compartments and mortality, acknowledging the compositional nature of human body, is not well-studied. Read More

Phys Rev Lett 2021 Mar;126(12):127405

Department of Physics and Astronomy, Aarhus University, Ny Munkegade, DK-8000 Aarhus C, Denmark.

Realizing strong photon-photon interactions in a solid-state setting is a major goal with far reaching potential for optoelectronic applications. Using Landau's quasiparticle framework combined with a microscopic many-body theory, we explore the interactions between exciton-polaritons and trions in a two-dimensional semiconductor injected with an electron gas inside a microcavity. We show that particle-hole excitations in the electron gas mediate an attractive interaction between the polaritons, whereas the interaction between trions and polaritons mediated by the exchange of an electron can be either repulsive or attractive. Read More

CellR4 Repair Replace Regen Reprogram 2017 20;5(3). Epub 2017 Jun 20.

Diabetes Research Institute and Cell Transplant Center, University of Miami, Miami, FL, USA.

The greater omentum is a highly vascularized anatomical structure in the peritoneal cavity. Its main components are connective, adipose and vascular cells, along with specialized immune cells. The omentum functions as a site for fat accumulation, it has adhesive properties to control traumatized and inflamed tissues, and a function in local hemostasis, immune responses, and revascularization. Read More

Front Psychiatry 2021 23;12:566740. Epub 2021 Mar 23.

Regional Center for Psychotraumatism Great East, Strasbourg University Hospital, Strasbourg, France.

The Coronavirus Disease 2019 (COVID-19) pandemic exposed health professionals to high stress levels inducing significant psychological impact. Our region, , was the most impacted French region during the first COVID-19 wave. In this context, we created CoviPsyHUS, local mental health prevention and care system dedicated explicitly to healthcare workers affected by the COVID-19 pandemic in one of this region's tertiary hospitals. Read More

Sci Rep 2021 Apr 8;11(1):7685. Epub 2021 Apr 8.

Aura Devices Inc., 1013 Centre Road, Suite 403-B, Wilmington, DE, 19805, USA.

Situational or persistent body fluid deficit (i.e., de- or hypo-hydration) is considered a significant health risk factor. Read More

BMC Med Inform Decis Mak 2021 Apr 8;21(1):121. Epub 2021 Apr 8.

School of Mechanical and Power Engineering, Henan Polytechnic University, Jiaozuo, 454000, China.

Background: The motion capture has been used as the usual method for measuring movement parameters of human, and most of the measuring data are obtained by partial manual process based on commercial software. An automatic kinematics data process was developed by programming on MATLAB software in this paper.

Methods: The motion capture measurement of healthy volunteers was carried out and the MATLAB program was used for data process. Read More

Eur J Sport Sci 2021 Apr 9:1-18. Epub 2021 Apr 9.

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University.

Decades of laboratory research have shown impairments to several body systems after only 4-5 days of strictly controlled consistent low energy availability (LEA); where energy availability (EA) = Energy Intake (EI) - Exercise Energy Expenditure (EEE) / Fat-Free Mass. Meanwhile, cross-sectional reports exist on the interrelatedness of LEA, menstrual dysfunction and impaired bone health in females (the Female Athlete Triad). These findings have demonstrated that LEA is the key underpinning factor behind a broader set of health and performance outcomes, recently termed as Relative Energy Deficiency in Sport (RED-S). Read More

Phytomedicine 2021 Mar 19;85:153548. Epub 2021 Mar 19.

College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China. Electronic address:

Background: Pterocephalus hookeri (C. B. Clarke) Höeck, a Tibetan medicine widely used for treatment of rheumatoid arthritis, was recorded in Chinese Pharmacopoeia (2020 version) with slight toxicity. Read More

PLoS One 2021 8;16(4):e0249782. Epub 2021 Apr 8.

Department of Biological and Experimental Psychology, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.

People make judgments of others based on appearance, and these inferences can affect social interactions. Although the importance of facial appearance in these judgments is well established, the impact of the body morphology remains unclear. Specifically, it is unknown whether experimentally varied body morphology has an impact on perception of threat in others. Read More

Am J Clin Nutr 2021 Apr 7. Epub 2021 Apr 7.

School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Australia.

Background: Reliability of body composition measurement techniques is essential to the accurate reporting of intervention outcomes. However, the between-day precision error of commonly used techniques, as well as the reference multi-compartment model, in a population-representative sample are currently unknown.

Objectives: To quantify technical and biological precision error of body composition techniques in comparison to the referent 4-compartment (4C) model. Read More

Front Endocrinol (Lausanne) 2021 22;12:655982. Epub 2021 Mar 22.

Department of Diagnostic Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, Houston, TX, United States.

The immune system and the neuroendocrine system share many common features. Both consist of diverse components consisting of receptors and networks that are widely distributed throughout the body, and both sense and react to external stimuli which, on the one hand control mechanisms of immunity, and on the other hand control and regulate growth, development, and metabolism. It is thus not surprising, therefore, that the immune system and the neuroendocrine system communicate extensively. Read More

Front Psychol 2021 22;12:636933. Epub 2021 Mar 22.

Istituto Auxologico Italiano, Psychology Research Laboratory, Milan, Italy.

Obesity is a global health problem that affects both physical and psychological health and well-being. Psychological flexibility is one of the key components related to psychological health. This cross-sectional study aims to investigate the impact of psychological flexibility on psychological well-being in a sample of 220 individuals with obesity. Read More

Exp Anim 2021 Apr 6. Epub 2021 Apr 6.

Laboratory of Extracellular Matrix Biochemistry, Institute for Protein Research, Osaka University.

Sea urchin embryos have been one of model organisms to investigate cellular behaviors because of their simple cell composition and transparent body. They also give us an opportunity to investigate molecular functions of human proteins of interest that are conserved in sea urchin. Here we report that human disease-associated extracellular matrix orthologues ECM3 and QBRICK are necessary for mesenchymal cell migration during sea urchin embryogenesis. Read More

BMC Public Health 2021 Apr 7;21(1):669. Epub 2021 Apr 7.

Department of Primary Teacher Education, Faculty of Educational Sciences, University of Pula, Pula, Croatia.

Background: Although evidence suggests that functional endurance capacity is the most important component associated with future health, little is known of how it is associated with multiple other physical fitness components. Since various physical fitness aspects do not change the same as functional endurance capacity during childhood, it is necessary to establish possible associations between functional endurance capacity and other physical fitness components in children. Therefore, the main purpose of the study was to test the associations between functional endurance capacity with other physical fitness components in 7-14-year-old children, stratified by gender. Read More

Am J Chin Med 2021 Apr 6:1-24. Epub 2021 Apr 6.

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Based on the study and research on the pathogenesis of colorectal cancer, the types and functions of gut microbiota, and its role in guiding and regulating the occurrence and development of diseases, we have explored the mechanism of traditional Chinese medicine in the treatment of colorectal cancer by regulating the gut microbiota. Genetic variation, abnormal responses of innate and adaptive immunity, mucosal barrier dysfunction, imbalance of intestinal microbial colonization, personal and environmental risk factors are the main pathogenesis of colorectal cancer. The gut microbiota mainly includes (including , , and ) and (including and ), which have biological antagonism, nutrition for the organism, metabolic abilities, immune stimulation, and ability to shape cancer genes functions to body. Read More

Am J Clin Nutr 2021 Apr 7. Epub 2021 Apr 7.

Translational Research Institute, AdventHealth, Orlando, FL, USA.

Background: Low-calorie diet (LCD)-induced weight loss demonstrates response heterogeneity. Physiologically, a decrease in energy expenditure lower than what is predicted based on body composition (metabolic adaptation) and/or an impaired capacity to increase fat oxidation may hinder weight loss. Understanding the metabolic components that characterize weight loss success is important for optimizing weight loss strategies. Read More

Mol Biol Cell 2021 Apr 7:mbcE20110717. Epub 2021 Apr 7.

Dept. of Molecular Biosciences, University of Texas, Austin, TX.

Intraflagellar transport (IFT) is essential for construction and maintenance of cilia. IFT proteins concentrate at the basal body, where they are thought to assemble into trains and bind cargoes for transport. To study the mechanisms of IFT recruitment to this peri-basal body pool, we quantified protein dynamics of eight IFT proteins, as well as five other basal body localizing proteins, using fluorescence recovery after photobleaching in vertebrate multiciliated cells. Read More

J Res Med Sci 2020 26;25:103. Epub 2020 Nov 26.

Department of Internal Medicine, Gastroenterologist, Shiraz Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Metabolic syndrome (MetS) is a cluster of conditions increasing the risk of serious diseases. This study aimed to define the predictors of MetS incident in a community-based cohort in Southern Iran, during a mean follow-up period of 5.1 years. Read More

Diabetes Metab Syndr Obes 2021 29;14:1453-1463. Epub 2021 Mar 29.

Department of OBGYN, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.

Purpose: Metabolic syndrome (MetS) has been reported as a deleterious factor in male fertility potential, associated with hypogonadism, impaired spermatogenesis, decreased sperm concentration and motility, and increased sperm DNA damage. This study aimed to determine the prevalence of MetS in men from infertile couples and evaluate its effect on semen analysis (SA).

Participants And Methods: A cross-sectional descriptive study was performed in men from infertile couples diagnosed based on the World Health Organization 2010 criteria and treated at the Hue Center for Reproductive Endocrinology and Infertility, Vietnam. Read More

Radiat Prot Dosimetry 2021 Apr 6. Epub 2021 Apr 6.

Nuclear Science & Technology Research Institute, Tehran, Iran.

High radiation doses to the body may lead to the stochastic/deterministic effects of ionizing radiation on the critical organs as well as causing the cataract in eye lens of the clinical staff in interventional radiology. In this study, the received doses of the eyes, skin and whole body of 38 clinical staff including physicians, residents, nurses and radiotechnologists in cardiac angiography departments in three selected hospitals were assessed using personal dosemeters during two bimonthly dosimetry periods. Moreover, the correlation coefficients among the measured dose components including eye lens dose, skin dose and whole body dose equivalent in both area of under and over their lead-apron were calculated for all these occupational groups. Read More

Phys Ther 2021 Apr 5. Epub 2021 Apr 5.

School of Nursing, University of Maryland, Baltimore, MD.

Objectives: Physical therapy intervention studies can be deemed ineffective when, in fact, they may not have been delivered as intended. Measurement of treatment fidelity (TF) can address this issue. The purpose was to describe TF of a home-based intervention, identify factors associated with TF, and examine whether components of TF were associated with the outcome of change in 6-minute walk distance (∆6MWD). Read More

PLoS One 2021 6;16(4):e0249626. Epub 2021 Apr 6.

The Faculty of Education, Health and Wellbeing, University of Wolverhampton, Wolverhampton, United Kingdom.

Regular participation in strength and conditioning activities positively correlates with health-related benefits in sports (team and individual). Maturity offset (MO) is a recognized parameter in fitness outcome assessment. The aims of the present study are to analyze cross-sectional allometric development of motor performances in a sample of adolescents and relate scaled motor performance to the estimated amount and type of physical activity and biological maturity status in 771 subjects aged 14-19 years. Read More

Ethn Health 2021 Apr 5:1-24. Epub 2021 Apr 5.

Department of Anthropology, Vidyasagar University, Midnapore, West Bengal, India.

Background: . Indian subcontinent exhibits considerable degree of ethnic heterogeneity in cardiovascular disease (CVD) risks. Given the importance of ethnicity, the present multi-ethnic study was conducted to find out the differences in body composition patterning and its influence on CVD risk variables. Read More