59,992 results match your criteria bmi group


Methodology for altering omega-3 EPA+DHA and omega-6 linoleic acid as controlled variables in a dietary trial.

Clin Nutr 2021 May 12;40(6):3859-3867. Epub 2021 May 12.

Department of Neurology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Background & Aims: Increasing dietary intake of n-3 EPA+DHA and lowering dietary n-6 LA is under investigation as a therapeutic diet for improving chronic pain syndromes as well as other health outcomes. Herein we describe the diet methodology used to modulate intake of n-3 and n-6 PUFA in a free living migraine headache population and report on nutrient intake, BMI and diet acceptability achieved at week 16 of the intensive diet intervention and week 22 follow-up time-point.

Methods: A total of 178 participants were randomized and began one of three diet interventions: 1) a high n-3 PUFA, average n-6 PUFA (H3) diet targeting 1500 mg EPA+DHA/day and 7% of energy (en%) from n-6 linoleic acid (LA), 2) a high-n-3 PUFA, low-n-6 PUFA (H3L6) targeting 1500 mg EPA+DHA/day and <1. Read More

View Article and Full-Text PDF

The effect of the a regional cardioprotective nutritional program on inflammatory biomarkers and metabolic risk factors in secondary prevention for cardiovascular disease, a randomised trial.

Clin Nutr 2021 Apr 28;40(6):3828-3835. Epub 2021 Apr 28.

Department of Nutrition, School of Public Health, University of São Paulo, São Paulo, Brazil. Electronic address:

Background & Aims: To evaluate the effect of the Brazilian Cardioprotective Diet Program (BALANCE Program) on inflammatory biomarkers, involved in the pathophysiology of the atherosclerosis, on inflammatory biomarkers, cardiovascular risk factors, and on plasma fatty acids in cardiovascular disease secondary prevention patients.

Methods: In this substudy of the BALANCE Program randomized clinical trial, a total of 369 patients aged 45 years or older, who have experienced cardiovascular disease in the previous 10 years, were included. These patients were randomized into two groups and followed up for six months: BALANCE Program group and control group (conventional nutrition advice). Read More

View Article and Full-Text PDF

Postprandial dynamics and response of fibroblast growth factor 21 in older adults.

Clin Nutr 2021 Apr 27;40(6):3765-3771. Epub 2021 Apr 27.

German Institute of Human Nutrition, Potsdam-Rehbrücke, Department of Nutrition and Gerontology, Nuthetal, Germany; University of Potsdam, Institute of Nutritional Science, Potsdam, Germany; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Department of Geriatrics, Berlin, Germany. Electronic address:

Background & Aims: Fibroblast growth factor 21 (FGF21) plays a pivotal role in glucose and lipid metabolism and has been proposed as a longevity hormone. However, elevated plasma FGF21 concentrations are paradoxically associated with mortality in higher age and little is known about the postprandial regulation of FGF21 in older adults. In this parallel group study, we investigated postprandial FGF21 dynamics and response in older (65-85 years) compared to younger (18-35 years) adults following test meals with varying macronutrient composition. Read More

View Article and Full-Text PDF

Implant failure following pedicle based dynamic stabilization of the lumbar spine.

Acta Orthop Belg 2021 Mar;87(1):191-196

Pedicle-based dynamic stabilization (PBDS) devices such as Dynesys are promoted as an alternative and less invasive option for rigid stabilization of one and even more levels of the lumbar spine. Promising features of the Dynesys system, as well as shortcomings, became obvious in several clinical studies. Since 2012, we started using a new PBDS device as an alternative for the Dynesys, to avoid the screw loosening and the kyphosing effect. Read More

View Article and Full-Text PDF

Immune status changing helps diagnose osteoarticular tuberculosis.

PLoS One 2021 15;16(6):e0252875. Epub 2021 Jun 15.

Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.

Objective: This study is aimed to develop a new nomogram for the clinical diagnosis of osteoarticular tuberculosis (TB).

Methods: xCell score estimation to obtained the immune cell type abundance scores. We downloaded the expression profile of GSE83456 from GEO and proceed xCell score estimation. Read More

View Article and Full-Text PDF

Efficacy of propiverine hydrochloride for urinary incontinence after robot-assisted or laparoscopic radical prostatectomy.

Can J Urol 2021 Jun;28(3):10706-10712

Department of Urology and Renal Transplantation, Nagasaki University Hospital, Nagasaki, Japan.

Introduction: To clarify the efficacy and safety of propiverine hydrochloride for incontinence after robot-assisted laparoscopic prostatectomy (RALP)/laparoscopic radical prostatectomy (LRP), along with changes in the urethral pressure profile (UPP) and quality of life in patients treated with propiverine hydrochloride.

Materials And Methods: In this randomized, comparative study, 104 patients who were aware of urinary incontinence after RALP or LRP were assigned to receive propiverine hydrochloride (treatment group) or not (controls). Pad test results, International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) scores, and UPP results [including maximum urethral closure pressure (MUCP) and functional urethral length (FUL)], were recorded immediately and at 6 months postoperatively. Read More

View Article and Full-Text PDF

Childhood adiposity associated with expanded effector memory CD8 + and Vδ2 +Vγ9 + T cells.

J Clin Endocrinol Metab 2021 Jun 15. Epub 2021 Jun 15.

Department of Pediatrics, Sophia Children's Hospital, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

Context: Adult obesity is associated with chronic low-grade inflammation and may give rise to future chronic disease. However, it is unclear whether adiposity-related inflammation is already apparent at young age.

Objective: To study associations between child's adiposity measures with circulating monocytes and naive and memory subsets in CD4, CD8, and γδ T-cell lineages. Read More

View Article and Full-Text PDF

Effects of atorvastatin on the insulin resistance in women of polycystic ovary syndrome: A systematic review and meta-analysis.

Medicine (Baltimore) 2021 Jun;100(24):e26289

Department of Gynecology, Tongde Hospital of Zhejiang Province, Hangzhou, China.

Background: Atorvastatin treatment has been suggested as a therapeutic method for women with polycystic ovary syndrome (PCOS) in many clinical studies. Nonetheless, the effects of atorvastatin on insulin resistance in PCOS patients still remain controversial.

Objective: The aim of this report was to evaluate the effects of atorvastatin therapy on the insulin resistance in the treatment of PCOS compared to that of placebo, in order to confer a reference for clinical practice. Read More

View Article and Full-Text PDF

Can robotic technology mitigate the learning curve of total hip arthroplasty?

Bone Jt Open 2021 Jun;2(6):365-370

Department of Orthopaedic Surgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

Aims: Traditionally, acetabular component insertion during total hip arthroplasty (THA) is visually assisted in the posterior approach and fluoroscopically assisted in the anterior approach. The present study examined the accuracy of a new surgeon during anterior (NSA) and posterior (NSP) THA using robotic arm-assisted technology compared to two experienced surgeons using traditional methods.

Methods: Prospectively collected data was reviewed for 120 patients at two institutions. Read More

View Article and Full-Text PDF

Status of Intestinal Helminth Infection in Schools Implementing the Home-Grown School Feeding Program and the Impact of the Program on Pupils in Anambra State, Nigeria.

Acta Parasitol 2021 Jun 14. Epub 2021 Jun 14.

Virology Department, College of Health Sciences, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.

Purpose: Intestinal helminthiasis among pupils is a major impediment to their well-being and development. This 2-year study determined how home-grown school feeding programme (HGSFP) impacted on pupils' school attendance and created opportunity for more children to assess interventions geared towards the prevention and possible elimination of intestinal helminthiasis.

Methods: Faecal samples were collected from 1677 consented pupils and examined for helminths using Kato-Katz technique. Read More

View Article and Full-Text PDF

Inter-individual body mass variations relate to fractionated functional brain hierarchies.

Commun Biol 2021 Jun 14;4(1):735. Epub 2021 Jun 14.

McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada.

Variations in body mass index (BMI) have been suggested to relate to atypical brain organization, yet connectome-level substrates of BMI and their neurobiological underpinnings remain unclear. Studying 325 healthy young adults, we examined associations between functional connectivity and inter-individual BMI variations. We utilized non-linear connectome manifold learning techniques to represent macroscale functional organization along continuous hierarchical axes that dissociate low level and higher order brain systems. Read More

View Article and Full-Text PDF

Effect of the type of specialized nutrition support on the course of the patient with amyotrophic lateral sclerosis (ALS). Interhospital registry SCLEDyN.

Endocrinol Diabetes Nutr 2021 Jun 11. Epub 2021 Jun 11.

Hospital Clínico Universitario de Valladolid, Valladolid, España; Instituto de Investigación en Endocrinología y Nutrición (IENVA), Universidad de Valladolid, Valladolid, España.

Introduction: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease in which specialized nutritional support is essential. The objectives of our study were to describe nutritional support at the beginning of follow-up and its impact on anthropometry and survival.

Methods: An interhospital registry was created for the hospitals of Castilla-León through a web platform designed for this purpose. Read More

View Article and Full-Text PDF

Clinical Assessment of Autonomic Function in Fibromyalgia by the Refined and Abbreviated Composite Autonomic Symptom Score (COMPASS 31): A Case-Controlled Study.

Rev Recent Clin Trials 2021 Jun 11. Epub 2021 Jun 11.

University of Southampton. United Kingdom.

Background: It has been shown that autonomic dysfunction in fibromyalgia can be assessed by the Composite Autonomic Symptom Score (COMPASS) questionnaire. More recently, a refined and much abbreviated 31-item version of the questionnaire has been developed, the COMPASS 31.

Objectives: The study has the following objectives: First, to determine whether the COMPASS 31 can assess changes in autonomic function in fibromyalgia. Read More

View Article and Full-Text PDF

[Clinical value of left ventricular strain analysis by cardiovascular magnetic resonance in patients with coronary chronic total occlusion].

Zhonghua Xin Xue Guan Bing Za Zhi 2021 Jun;49(6):601-609

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029,China.

To explore the clinical value of quantitatively assessment of left ventricular strain in patients with coronary chronic total occlusion (CTO) by cardiac magnetic resonance imaging (CMR)-feature tracking (CMR-FT) technique. In this retrospective and observation study, patients with single CTO, who underwent CMR examination in Beijing Anzhen Hospital from November 2014 to January 2019, were selected as case group (CTO group), and those without cardiovascular diseases defined by echocardiography, electrocardiogram (ECG) and clinical history and with normal CMR results were selected as healthy control group (control group). General clinical data including age, gender, discharge diagnosis, and the examination results of echocardiography and ECG were obtained from the electronic medical record system. Read More

View Article and Full-Text PDF

Urinary triclosan in south China adults and implications for human exposure.

Environ Pollut 2021 Jun 9;286:117561. Epub 2021 Jun 9.

School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou, China. Electronic address:

Triclosan (TCS) is widely applied in personal care products (PCPs) as an antimicrobial preservative. Due to its toxicity and potential risk to human health, TCS has attracted mounting concerns in recent years. However, biomonitoring of TCS in large human populations remains limited in China. Read More

View Article and Full-Text PDF

Endoscopic versus surgical gastrojejunal revision for weight regain in Roux-en-Y gastric bypass patients: 5-year safety and efficacy comparison.

Gastrointest Endosc 2021 Jun 11. Epub 2021 Jun 11.

Division of Gastroenterology, Hepatology and Endoscopy. Brigham and Women's Hospital. Harvard Medical School. Boston, MA. Electronic address:

Background And Aims: An enlarged gastrojejunal anastomosis (GJA) is associated with weight regain after Roux-en-Y (RYGB) and can be corrected with endoscopic (ENDO) or surgical (SURG) revision; however, there has been no direct comparison between techniques. This study aims to compare serious adverse event (SAE) rates and weight loss profiles between ENDO and SURG revisional techniques over a 5-year period.

Methods: Retrospective matched cohort study of RYGB patients who underwent ENDO or SURG revision for weight regain with an enlarged GJA (>12 mm). Read More

View Article and Full-Text PDF

Effects of Vitamin D Supplefmentation on Outcome of Low-Calorie Diet in Workers Presenting Obesity or Overweight: A Retrospective Observational Study.

J Am Coll Nutr 2021 Jun 14:1-9. Epub 2021 Jun 14.

Department of Preventive Medicine, Occupational Health Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Aim: Growing evidence underscores the inverse association between serum vitamin D (vit D) and chronic conditions such as metabolic syndrome, diabetes and obesity. The aim of this retrospective study was to compare weight loss and metabolic serum biomarkers in subjects on low-calorie diet receiving vit D supplementation versus those not receiving it.

Methods: The study considered 405 indoor sedentary workers with overweight/obesity and vit D insufficiency, who participated to a health fitness program between 2011-2013. Read More

View Article and Full-Text PDF

Keyto App and Device versus WW App on Weight Loss and Metabolic Risk in Adults with Overweight or Obesity: A Randomized Trial.

Obesity (Silver Spring) 2021 Jun 14. Epub 2021 Jun 14.

University of British Columbia, Kelowna, BC, Canada.

Objective: To determine whether a Mediterranean-style ketogenic diet mobile health application (app) with breath acetone biofeedback is superior to a calorie-restricted low-fat diet app in promoting weight loss.

Methods: Participants (N = 155) with overweight/obesity (mean±SD: 41±11 y, BMI = 34±5 kg/m , 71% female) were randomized to one of the interventions that were delivered entirely via app. Participants received a wireless scale and were instructed to take daily weight measurements. Read More

View Article and Full-Text PDF

Dietary Selenium Intake and Type-2 Diabetes: A Cross-Sectional Population-Based Study on CUME Project.

Front Nutr 2021 28;8:678648. Epub 2021 May 28.

Faculty of Biological and Health Sciences, Department of Nutrition, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil.

Previous studies have suggested that the specific association between selenium (Se) and diabetes remains unclear. This study aimed to investigate the association between dietary Se and type-2 diabetes (T2D) in the Brazilian cohort [Cohort of Universities of Minas Gerais (CUME)]. This cross-sectional study was conducted with a large sample comprising 4,106 participants of the CUME project, a concurrent open cohort restricted to a highly educated population group, composed of graduates of federal institutions of higher education located in the State of Minas Gerais, Brazil. Read More

View Article and Full-Text PDF

Comparison of Peak Oxygen Consumption During Exercise Testing Between Sexes Among Children and Adolescents in Taiwan.

Front Pediatr 2021 28;9:657551. Epub 2021 May 28.

Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Studies among Western children have observed that the peak oxygen consumption (peak O) of boys is higher than that of girls, and this difference increases as children progress through adolescence. However, the maturation process and social expectation toward Eastern boys and girls are much different from their Western counterparts. This study aimed to provide baseline information on cardiopulmonary fitness (CRF) of Taiwanese children and adolescents in relation to age and sex. Read More

View Article and Full-Text PDF

National School-Based Health Lifestyles Intervention in Chinese Children and Adolescents on Obesity and Hypertension.

Front Pediatr 2021 28;9:615283. Epub 2021 May 28.

School of Public Health, Institute of Child and Adolescent Health, Peking University, Beijing, China.

This study aimed to examine the effectiveness of the national school-based intervention on both obesity and high blood pressure in Chinese children and adolescents aged 6-18 years. The national school-based cluster non-randomized controlled trial was done in seven provinces from September 2013 to February 2014. A total of 23,175 children and adolescents in the control group and 25,702 in the intervention group were included in this trial with a mean follow-up of 6. Read More

View Article and Full-Text PDF

Enhanced Susceptibility to Breast Cancer in Korean Women With Elevated Serum Gamma-Glutamyltransferase Levels: A Nationwide Population-Based Cohort Study.

Front Oncol 2021 27;11:668624. Epub 2021 May 27.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea.

Background: The incidence of breast cancer has been gradually increasing in Korea. Recently, the elevated level of serum gamma-glutamyltransferase (GGT) has emerged to be associated with the development and progression of some malignancies. This study aimed to determine the effect of serum GGT levels on the risk of developing breast cancer in Korean women. Read More

View Article and Full-Text PDF

The Immediate Effects of Foam Rolling and Stretching on Iliotibial Band Stiffness: A Randomized Controlled Trial.

Int J Sports Phys Ther 2021 Jun 1;16(3):651-661. Epub 2021 Jun 1.

Texas Tech University Health Sciences Center, Lubbock, TX.

Background: Iliotibial Band Syndrome (ITBS) is a common clinical condition likely caused by abnormal compressive forces to the iliotibial band (ITB). Stretching interventions are common in ITBS treatment and may predominantly affect tensor fascia latae (TFL). Another ITBS treatment is foam rolling, which may more directly affect the ITB. Read More

View Article and Full-Text PDF

Association between TSH Values and GFR Levels in Euthyroid Cases with Metabolic Syndrome.

Int J Endocrinol 2021 26;2021:8891972. Epub 2021 May 26.

Department of Biostatistics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background: Metabolic syndrome (MetS) is associated with the risk of developing chronic kidney disease. Although the negative effects of high thyroid-stimulating hormone (TSH) values on glomerular filtration rate (GFR) levels have been known for years, the negative effects of increased TSH on GFR in euthyroid cases have been reported in recent years. This study was aimed at investigating the association between the effect of increased TSH values and estimated-GFR (eGFR) levels in euthyroid cases with MetS. Read More

View Article and Full-Text PDF

High Serum Anti-Müllerian Hormone Concentrations Are Associated With Poor Pregnancy Outcome in Fresh IVF/ICSI Cycle but Not Cumulative Live Birth Rate in PCOS Patients.

Front Endocrinol (Lausanne) 2021 26;12:673284. Epub 2021 May 26.

Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: To investigate the association between baseline serum Anti-Müllerian hormone (AMH) levels and IVF/ICSI outcomes in women with polycystic ovary syndrome (PCOS).

Design: Retrospective study.

Setting: Reproductive medicine center in a hospital. Read More

View Article and Full-Text PDF

Adverse Effects of Selected Markers on the Metabolic and Endocrine Profiles of Obese Women With and Without PCOS.

Front Endocrinol (Lausanne) 2021 26;12:665446. Epub 2021 May 26.

Zoology Department, Science College, King Saud University, Riyadh, Saudi Arabia.

The aim of the present study, is to investigate the influence of obesity, with and without polycystic ovarian syndrome (PCOS), on the levels of kisspeptin, vitamin D (Vit D), and vascular endothelial growth factor (VEGF) and to explore the relationship between these parameters and endocrine and metabolic variables. The study group included 126 obese Saudi females. Of these 63 were suffering from PCOS while the rest were normo-ovulatory obese women (non-PCOS obese). Read More

View Article and Full-Text PDF

Objectively Measured Physical Activity Is Associated With Body Composition and Metabolic Profiles of Pacific and New Zealand European Women With Different Metabolic Disease Risks.

Front Physiol 2021 26;12:684782. Epub 2021 May 26.

School of Sport, Exercise and Nutrition, Massey University, Auckland, New Zealand.

To assess associations between physical activity (PA), body composition, and biomarkers of metabolic health in Pacific and New Zealand European (NZE) women who are known to have different metabolic disease risks. Pacific ( = 142) or NZE ( = 162) women aged 18-45 years with a self-reported body mass index (BMI) of either 18.5-25. Read More

View Article and Full-Text PDF

Nontargeted Metabolomic Analysis of Plasma Metabolite Changes in Patients with Adolescent Idiopathic Scoliosis.

Mediators Inflamm 2021 25;2021:5537811. Epub 2021 May 25.

Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.

Objective: Adolescent idiopathic scoliosis (AIS) is a relatively common spinal rotation deformity, and the pathogenesis of AIS is accompanied by metabolic dysfunction and changes in biochemical factors. In this study, plasma metabolite changes in AIS patients were analyzed based on nontargeted metabolomics to provide new insights for clarifying functional metabolic abnormalities in AIS patients.

Methods: Clinical indexes and blood samples were collected from 12 healthy subjects and 16 AIS patients. Read More

View Article and Full-Text PDF

Association of Angiotensin-Converting Enzyme gene polymorphism in Pakistani women with the atypical steroidogenesis in Polycystic ovarian syndrome: A case-control study.

Saudi J Biol Sci 2021 Jun 14;28(6):3483-3489. Epub 2021 Mar 14.

Department of Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan.

Background: Polymorphism in the angiotensin-converting enzyme gene (ACE) is responsible for elevated ACE concentrations in plasma. High ACE levels induce insulin resistance and hyperandrogenism, which are the main attributes of polycystic ovary syndrome (PCOS). Therefore, it was hypothesized that I/D polymorphism plays a role in the pathogenesis of PCOS. Read More

View Article and Full-Text PDF

Prevalence of ApoB100 rs693 gene polymorphism in metabolic syndrome among female students at King Abdulaziz University.

Saudi J Biol Sci 2021 Jun 25;28(6):3249-3253. Epub 2021 Feb 25.

Biochemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Apolipoprotein B100 (ApoB100) is a glycoprotein and a member of the adipokine family. It plays a central role in lipoprotein metabolism. Many research studies have revealed a strong relation between ApoB100 and metabolic syndrome (MetS) and insulin resistance. Read More

View Article and Full-Text PDF