Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2020 Nov;32(11):1340-1345
Department of Internal Medicine, Xushi Hospital of Changshu City, Changshu 215501, Jiangsu, China. Corresponding author: You Nianxing, Email:
Objective: To analyze the risk factors of neurological function recovery and occurrence of cerebral hemorrhage transformation (HT) after recombinant tissue-type plasiminogen activator (re-PA) in patients with acute ischemic stroke (AIS).
Methods: The 173 patients with AIS who received rt-PA thrombolysis in Changshu Hospital of Xuzhou Medical University from March, 2018 to January, 2020 were selected as research objects, and they were divided into HT group (46 cases) and non HT group (127 cases) according to whether HT occurred. The data such as gender, age, body mass index (BMI), past histories including smoking, drinking, hypertension, diabetes mellitus, stroke, atrial fibrillation, coronary heart disease, National Institutes of Health Stroke Scale (NIHSS) score before thrombolysis, systolic blood pressure before thrombolysis, diastolic blood pressure before thrombolysis, hemoglobin, blood glucose, triglyceride, total cholesterol, thrombolytic time, responsible infarction, CT low density foci, estimated glomerular filtration rate (eGFR), serum uric acid (SUA) and fibrinogen (Fib) were collected. Read More