540 results match your criteria bmi 266

Exploring early combination strategy in Latin American patients with newly diagnosed type 2 diabetes: a sub-analysis of the VERIFY study.

Diabetol Metab Syndr 2021 Jun 15;13(1):68. Epub 2021 Jun 15.

Children's Hospital, Helsinki University and Helsinki University Hospital, Helsinki, Finland.

Background: Patients with type 2 diabetes mellitus (T2DM) from Latin American countries face challenges in access to healthcare, leading to under-diagnosis, under-achievement of glycemic target, and long-term complications. Early diagnosis and treatment initiation are of paramount importance in this population due to the high prevalence of risk factors such as obesity and metabolic syndrome. The VERIFY study in patients with newly diagnosed T2DM (across 34 countries), assessed the normoglycemic durability (5 years), with early combination (EC) therapy approach versus the traditional stepwise approach of initiating treatment with metformin monotherapy (MET). Read More

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Efficacy of propiverine hydrochloride for urinary incontinence after robot-assisted or laparoscopic radical prostatectomy.

Can J Urol 2021 Jun;28(3):10706-10712

Department of Urology and Renal Transplantation, Nagasaki University Hospital, Nagasaki, Japan.

Introduction: To clarify the efficacy and safety of propiverine hydrochloride for incontinence after robot-assisted laparoscopic prostatectomy (RALP)/laparoscopic radical prostatectomy (LRP), along with changes in the urethral pressure profile (UPP) and quality of life in patients treated with propiverine hydrochloride.

Materials And Methods: In this randomized, comparative study, 104 patients who were aware of urinary incontinence after RALP or LRP were assigned to receive propiverine hydrochloride (treatment group) or not (controls). Pad test results, International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) scores, and UPP results [including maximum urethral closure pressure (MUCP) and functional urethral length (FUL)], were recorded immediately and at 6 months postoperatively. Read More

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Enhanced Susceptibility to Breast Cancer in Korean Women With Elevated Serum Gamma-Glutamyltransferase Levels: A Nationwide Population-Based Cohort Study.

Front Oncol 2021 27;11:668624. Epub 2021 May 27.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea.

Background: The incidence of breast cancer has been gradually increasing in Korea. Recently, the elevated level of serum gamma-glutamyltransferase (GGT) has emerged to be associated with the development and progression of some malignancies. This study aimed to determine the effect of serum GGT levels on the risk of developing breast cancer in Korean women. Read More

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Prevalence and factors associated with overweight and obesity in Kenya.

Prev Med Rep 2021 Jun 1;22:101340. Epub 2021 Mar 1.

Texas A&M University, 266 GGB, 2929 Research Pw, College Station, TX 77843, United States.

Overweight and obesity rates continue to rise globally and are associated with increased chronic disease morbidity and mortality. There is evidence of high overweight and obesity prevalence in Kenya, however; a gap exists in the knowledge of national prevalence and predictors of overweight and obesity. This cross-sectional study examined data from the 2015 World Health Organization (WHO) Kenya STEPwise Survey-the first nationally representative survey to objectively measure body mass index (BMI) among Kenyan men and women. Read More

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Preinjury Functional Independence is not Associated with Discharge Location in Older Trauma Patients.

J Surg Res 2021 Jun 4;266:413-420. Epub 2021 Jun 4.

Department of Surgery, University of Wisconsin School of Medicine, Madison, WI.

Background: The purpose of this study was to evaluate the association between pre-injury Katz Index of Independence in Activities of Daily Living (Katz ADL) functional status and discharge to a facility in non-neurologically injured older trauma patients.

Methods: Data were obtained from 207 patients in the Trauma Medical Home study cohort. Multivariable logistic regression was performed to identify factors associated with non-home discharge. Read More

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Preoperative and Intraoperative Blood Pressure Variability Independently Correlate With Outcomes.

J Surg Res 2021 Jun 1;266:387-397. Epub 2021 Jun 1.

University of North Dakota School and Medicine and Health Sciences, Grand Forks, North Dakota; University of North Dakota, Grand Forks, North Dakota; University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota. Electronic address:

Background: Blood pressure variability (BPV) describes visit-to-visit blood pressure (BP) changes independent of hypertension. Preoperative BPV and intraoperative BPV are associated with increased postoperative outcomes. We investigated the impact of both preoperative BPV and intraoperative BPV on elective surgical outcomes, specifically whether preoperative BPV and intraoperative BPV were independent risk factors for surgical complications. Read More

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Mortality After Elective Surgery: The Potential Role for Preoperative Palliative Care.

J Surg Res 2021 May 10;266:44-53. Epub 2021 May 10.

Department of Surgery, University of Minnesota Medical School, Minneapolis, MN.

Background: Preoperative optimization is increasingly emphasized for high-risk surgical patients. One critical component of this includes preoperative advanced care planning to promote goal-concordant care. We aimed to define a subset of patients that might benefit from preoperative palliative care consult for advanced care planning. Read More

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Rhabdomyolysis in Severe COVID-19: Male Sex, High BMI, and Prone Positioning Confer High Risk.

J Surg Res 2021 Apr 6;266:35-43. Epub 2021 Apr 6.

Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

Background: Bedside experience and studies of critically ill patients with coronavirus disease 2019 (COVID-19) indicate COVID-19 to be a devastating multisystem disease. We aim to describe the incidence, associated variables, and outcomes of rhabdomyolysis in critically ill COVID-19 patients.

Materials And Methods: Data for all critically ill adult patients (≥18 years old) admitted to the ICU at a large academic medical center with confirmed COVID-19 between March 13, 2020 and April 18, 2020 were prospectively collected. Read More

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Natural course of metabolically healthy phenotype and risk of developing Cardiometabolic diseases: a three years follow-up study.

BMC Endocr Disord 2021 Apr 28;21(1):85. Epub 2021 Apr 28.

Unidad de Investigación de Enfermedades Metabólicas, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15. CP 14080; Tlalpan, México City, Mexico.

Background: Whether the metabolically healthy obese (MHO) phenotype is a single, stable or a transitional, fluctuating state is currently unknown. The Mexican-Mestizo population has a genetic predisposition for the development of type 2 diabetes (T2D) and other cardiometabolic complications. Little is known about the natural history of metabolic health in this population. Read More

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Factors associated with birthweight decline in Japan (1980-2004).

BMC Pregnancy Childbirth 2021 Apr 27;21(1):337. Epub 2021 Apr 27.

Department of Nutrition, Aomori University of Health and Welfare, Aomori, Japan.

Background: Birthweight has been declining consistently for more than 30 years in Japan. This rapid rise in low birthweight is one of the worst among the countries of the Organization for Economic Co-operation and Development. We examined potential determinants of birthweight decline in Japan. Read More

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Risk factors and clinical outcomes associated with blood culture contamination.

Infect Control Hosp Epidemiol 2021 Apr 26:1-7. Epub 2021 Apr 26.

Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Objective: To determine patient-specific risk factors and clinical outcomes associated with contaminated blood cultures.

Design: A single-center, retrospective case-control risk factor and clinical outcome analysis performed on inpatients with blood cultures collected in the emergency department, 2014-2018. Patients with contaminated blood cultures (cases) were compared to patients with negative blood cultures (controls). Read More

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Interpregnancy Body Mass Index Change and Offspring Mortality Risk following the Second Pregnancy.

Am J Perinatol 2021 Apr 20. Epub 2021 Apr 20.

Department of Medicine, University Diabetes and Endocrinology Center, University of Utah, Salt Lake City, Utah.

Objective:  The aim of the study is to examine the impact of maternal interpregnancy body mass index (BMI) change on subsequent offspring mortality risk.

Study Design:  This is a retrospective cohort study of women who had two consecutive live singleton deliveries of at least 20 weeks' gestation from the Utah Population Database. Our exposure was defined as interpregnancy BMI change from the date of first delivery to the conception date of subsequent pregnancy. Read More

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The relationship between famine exposure during early life and ascending aorta dilatation in adults.

Br J Nutr 2021 Apr 5:1-8. Epub 2021 Apr 5.

Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, People's Republic of China.

The relationship between exposure to famine in early life and the risk of ascending aorta dilatation (AAD) in adulthood is still unclear; therefore, we aimed to examine the association in the Chinese population. We investigated the data of 2598 adults who were born between 1952 and 1964 in Guangdong, China. All enrolled subjects were categorised into five groups: not exposed to famine, exposed during fetal period, and exposed during early, mid or late childhood. Read More

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Pre-Pregnancy Diet Quality Is Associated with Lowering the Risk of Offspring Obesity and Underweight: Finding from a Prospective Cohort Study.

Nutrients 2021 Mar 24;13(4). Epub 2021 Mar 24.

Centre for Longitudinal and Life Course Research, School of Public Health, Faculty of Medicine, University of Queensland, 266 Herston Road, Brisbane, QLD 4006, Australia.

Maternal diet plays a critical role in epigenetic changes and the establishment of the gut microbiome in the fetus, which has been associated with weight outcomes in offspring. This study examined the association between maternal diet quality before pregnancy and childhood body mass index (BMI) in offspring. There were 1936 mothers with 3391 children included from the Australian Longitudinal Study on Women's Health (ALSWH) and the Mothers and their Children's Health (MatCH) study. Read More

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Insulin resistance and high molecular weight adiponectin in obese and non-obese patients with Polycystic Ovarian Syndrome (PCOS).

BMC Endocr Disord 2021 Mar 9;21(1):45. Epub 2021 Mar 9.

Endocrinology and Metabolism Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, 71345-1414, Iran.

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy among young women. Insulin resistance is a key feature in the pathogenesis of PCOS; also high molecular weight adiponectin is a marker of insulin resistance. The aim of this study was to evaluate the insulin resistance, metabolic and androgenic profiles and high molecular weight adiponectin in obese and non-obese PCOS patients. Read More

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High anti-Müllerian hormone levels might not reflect the likelihood of clinical pregnancy rate in IVF/ICSI treatment.

JBRA Assist Reprod 2021 Apr 27;25(2):266-271. Epub 2021 Apr 27.

Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University International Hospital, Beijing, 102206, China.

Objective: To investigate if high anti-Müllerian hormone (AMH) concentration is a useful tool to predict the outcome of assisted reproductive treatment.

Methods: Retrospective cohort study involving 520 patients who underwent IVF/ICSI procedures in a university hospital. We measured the serum AMH level on day 3 of the menstrual cycle. Read More

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Operatively treated ankle fractures in Switzerland, 2002-2012: epidemiology and associations between baseline characteristics and fracture types.

BMC Musculoskelet Disord 2021 Mar 11;22(1):266. Epub 2021 Mar 11.

Department of Orthopaedic Surgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland.

Background: Ankle fractures are common, and their incidence has been increasing. Previous epidemiological studies have been conducted in the US, Scandinavia, and Scotland. Our objectives were to provide a current epidemiological overview of operatively treated ankle fractures and to evaluate the influence of age, sex, lifestyle factors, and comorbidities on fracture types. Read More

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Musculoskeletal disorders (MSDs) and their associated factors among quarry workers in Nigeria: A cross-sectional study.

Heliyon 2021 Feb 3;7(2):e06130. Epub 2021 Feb 3.

Faculty of Medicine Ebonyi State University, Abakaliki, Nigeria.

Quarry workers are commonly afflicted with musculoskeletal disorders (MSDs). This health problem has been recognized as a significant threat to the quarry workers' safety but is rarely reported, particularly in Nigeria. Therefore, this study aimed to assess the prevalence of MSDs and their associated factors among quarry workers. Read More

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February 2021

Food quality score and anthropometric status among 6-year-old children: A cross-sectional study.

Int J Clin Pract 2021 Jun 11;75(6):e14102. Epub 2021 Mar 11.

Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.

Objective: Weight status and growth during childhood are indicative of healthy development throughout the lifespan. It is well understood that dietary patterns and overall quality of diet can prevent disease, improve health status and optimise growth and development. The current study investigates the relationship between overall diet quality and measures of childhood development including body mass index and height-for-age in 6-year-old children. Read More

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Magnitude and Associated Factors of Metabolic Syndrome Among Adult Urban Dwellers of Northern Ethiopia.

Diabetes Metab Syndr Obes 2021 10;14:589-600. Epub 2021 Feb 10.

Department of Nutrition and Dietetics, Faculty of Public Health, Jimma University, Jimma, Ethiopia.

Background: Metabolic Syndrome (MetS) is becoming a big public health problem in developing countries like Ethiopia. Developing countries have an almost two-fold higher risk of death due to non-communicable diseases (NCDs) compared to high-income countries. This study aimed to assess the magnitude and factors associated with MetS among adult residents of Mekelle city. Read More

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February 2021

Normalized Protein Catabolic Rate Is a Superior Nutritional Marker Associated With Dialysis Adequacy in Continuous Ambulatory Peritoneal Dialysis Patients.

Front Med (Lausanne) 2020 12;7:603725. Epub 2021 Jan 12.

Division of Nephrology, Department of Medicine, West China Hospital, Sichuan University, Chengdu, China.

Current knowledge of the relationship between normalized protein catabolic rate (nPCR) and dialysis adequacy is limited. Our study aimed to explore the potential relationship between nPCR and dialysis adequacy. In this cross-sectional study, we analyzed the association of nPCR with peritoneal dialysis adequacy in 266 continuous ambulatory peritoneal dialysis (CAPD) patients (mean age 48. Read More

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January 2021

The impact of anthropometric parameters on colorectal cancer prognosis: A systematic review and meta-analysis.

Crit Rev Oncol Hematol 2021 Mar 23;159:103232. Epub 2021 Jan 23.

Division of Gastroenterology, Department of Medicine, NYU Langone Health, VA New York Harbor Health Care System, New York, NY, 10010, USA. Electronic address:

Background & Aims: Our study aims to clarify the relationship between weight parameters and colorectal cancer outcomes.

Methods: NCBI, Embase, Cochrane, and Web of Science were searched from inception to December 2019. Studies reporting colorectal cancer (CRC) mortality, recurrence, disease-free survival, overall survival, overall mortality stratified by pre-diagnosis BMI or post-diagnosis weight change, were included in the analysis. Read More

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Benign ethnic neutropenia in a South African population, and its association with HIV acquisition and adverse event reporting in an HIV vaccine clinical trial.

PLoS One 2021 22;16(1):e0241708. Epub 2021 Jan 22.

Faculty of Health Sciences, Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa.

Benign ethnic neutropenia (BEN) is defined as a neutrophil count of <1.5×109 cells/L in healthy individuals and is more common in populations of certain ethnicities, e.g. Read More

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Safety And Efficacy Of Dpp-4 Inhibitors For The Management Of Hospitalized General Medicine And Surgery Patients with Type 2 Diabetes.

Endocr Pract 2020 Jul 24;26(7):722-728. Epub 2020 Nov 24.

Department of Medicine, Emory University School of Medicine. Electronic address:

Objective: DPP-4 inhibitors (DPP-4i) have been shown to be effective for the management of inpatient diabetes. We report pooled data from 3 prospective studies using DPP-4i in general medicine and surgery patients with type 2 diabetes (T2D).

Methods: We combined data from 3 randomized studies comparing DPP-4i alone or in combination with basal insulin or a basal-bolus insulin regimen. Read More

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Ghrelin, resistin and insulin in obese diabetic women in Wad-Madani, Sudan.

Afr Health Sci 2020 Mar;20(1):266-276

Department of Molecular Biology, Institute of Cancer, University of Gezira, Madani, Sudan.

Background: Obesity in the Sudan is increasing at alarming rate with the tendency of reaching an epidemic proportion in women. It is commonly associated with type 2 diabetes (T2D). Some adipokine hormones such as resistin are associated with obesity. Read More

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MiRNA Expression in Patients with Gaucher Disease Treated with Enzyme Replacement Therapy.

Life (Basel) 2020 Dec 22;11(1). Epub 2020 Dec 22.

Clinical Department of Metabolic Diseases and Diabetology, University Hospital in Krakow, 30-688 Kraków, Poland.

Aims: The aim of the work was to establish potential biomarkers or drug targets by analysing changes in miRNA concentration among patients with Gaucher disease (GD) compared to in healthy subjects.

Methods: This study was an observational, cross-sectional analysis of 30 adult participants: 10 controls and 20 adults with GD type 1. Patients with GD type 1 were treated with enzyme replacement therapy (ERT) for at least two years. Read More

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December 2020

Prevalence and predicting factors of metabolic-associated fatty liver disease diagnosed by transient elastography with controlled attenuation parameters in HIV-positive people.

Int J STD AIDS 2021 Mar 18;32(3):266-275. Epub 2020 Dec 18.

Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.

Metabolic disorders are increasing in people living with HIV (PLWH), and metabolic associated fatty liver disease (MAFLD) has become a common complication. A cross-sectional study was conducted in HIV-positive persons receiving anti-retroviral therapy (ART), in order to determine the prevalence and predicting factors of MAFLD in PLWH. All participants underwent bioelectrical impedance analysis, ultrasonography, and transient elastography with controlled attenuation parameter (CAP). Read More

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Sex Differences in the Influence of Sleep on Body Mass Index and Risk of Metabolic Syndrome in Middle-Aged Adults.

Healthcare (Basel) 2020 Dec 14;8(4). Epub 2020 Dec 14.

Youth Independence & Competencies Research Office, National Youth Policy Institute, Social Policy BLDG, Sejong National Research Complex, 370, Sicheong-daero, Sejong-si 30147, Korea.

Poor sleep and obesity are intimately related to cardiovascular diseases. We aimed to examine whether the influence of sleep and body mass index (BMI) on the risk of metabolic syndrome (MetS) differed by sex in middle-aged people. It is a cross-sectional study of 458 Korean participants who completed self-administered surveys; the data were analyzed using the PROCESS macro for SPSS. Read More

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December 2020

Targeting persistent normal left ventricular geometry in the general population: a 25-year follow-up study.

J Hypertens 2021 May;39(5):952-960

Department of Medicine and Surgery, University of Milano-Bicocca.

Aim: Findings regarding the extent of persistence over time of normal left ventricular (LV) geometry, a reference healthy echocardiographic phenotype, in the community are scanty. We sought to assess this issue in members of the general population enrolled in the Pressioni Arteriose Monitorate e Loro Associazioni study.

Methods: The study included 433 participants who attended the second and third survey of the Pressioni Arteriose Monitorate e Loro Associazioni study performed after 10 and 25 years from the initial evaluation. Read More

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