42,009 results match your criteria blood oxygenation


Sports compression garments improve resting markers of venous return and muscle blood flow in male basketball players.

J Sport Health Sci 2021 Jul 24. Epub 2021 Jul 24.

Institute for Health and Sport (iHeS), Victoria University, Footscray, VIC 3011, Australia; Department of Physiology, Australian Institute of Sport, Bruce, ACT 2617, Australia.

Background: The benefits associated with sports compression garments are thought to be closely related to enhanced blood flow. However, findings are equivocal, possibly due to heterogeneity in techniques used for measuring blood flow, garment types used, and pressures applied. This study combined Doppler ultrasound and near-infrared spectroscopy technologies to provide the first comprehensive assessment of the effects of three sports compression garment types on markers of venous return and muscle blood flow at rest. Read More

View Article and Full-Text PDF

Impact of Head-of-Bed Posture on Brain Oxygenation in Patients with Acute Brain Injury: A Prospective Cohort Study.

Neurocrit Care 2021 Jul 26. Epub 2021 Jul 26.

Department of Anesthesiology and Critical Care, Ramsay Santé Private Hospital De La Loire, Saint-Etienne, France.

Background: Therapeutic head positioning plays a role in the management of patients with acute brain injury. Although intracranial pressure (ICP) is typically lower in an upright posture than in a flat position, limited data exist concerning the effect of upright positioning on brain oxygenation and circulation. We sought to determine the impact of supine (0°) and semirecumbent (15° and 30°) postures on ICP, brain oxygenation, and brain circulation. Read More

View Article and Full-Text PDF

Clinical and radiological findings of silent hypoxia among COVID-19 patients.

J Infect Chemother 2021 Jul 8. Epub 2021 Jul 8.

Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.

The aim of this study was to describe the clinical and radiological findings of COVID-19 patients with "silent hypoxia," who had no dyspnea on admission even though their oximetry saturation was less than 94%. This retrospective cohort study included all COVID-19 patients (n = 270) at a large tertiary care hospital between January 31 and August 31, 2020. Clinical and radiological characteristics of patients who met our criteria of "silent hypoxia", which included those who reported no dyspnea even though oximetry saturation was <94%, were extracted. Read More

View Article and Full-Text PDF

Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study.

Acute Crit Care 2021 Jul 26. Epub 2021 Jul 26.

Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: High-flow nasal cannula (HFNC) became a popular tool for oxygen delivery, and its use in hypercapnia patients is gaining interest. However, evidence for using HFNC in hypercapnia is still limited. Most of the clinical studies had been conducted retrospectively, and there had been conflicting reports for the effects of HFNC on hypercapnia correction in prospective studies. Read More

View Article and Full-Text PDF

Multi-Band Brain Network Analysis for Functional Neuroimaging Biomarker Identification.

IEEE Trans Med Imaging 2021 Jul 26;PP. Epub 2021 Jul 26.

The functional connectomic profile is one of the non-invasive imaging biomarkers in the computer-assisted diagnostic system for many neuro-diseases. However, the diagnostic power of functional connectivity is challenged by mixed frequency-specific neuronal oscillations in the brain, which makes the single Functional Connectivity Network (FCN) often underpowered to capture the disease-related functional patterns. To address this challenge, we propose a novel functional connectivity analysis framework to conduct joint feature learning and personalized disease diagnosis, in a semi-supervised manner, aiming at focusing on putative multi-band functional connectivity biomarkers from functional neuroimaging data. Read More

View Article and Full-Text PDF

A compact integrated microfluidic oxygenator with high gas exchange efficiency and compatibility for long-lasting endothelialization.

Lab Chip 2021 Jul 26. Epub 2021 Jul 26.

Université Paris-Saclay, CNRS, Centre de Nanosciences et Nanotechnologies C2N, UMR9001, Palaiseau 91120, France.

We have developed and tested a novel microfluidic device for blood oxygenation, which exhibits a large surface area of gas exchange and can support long-term sustainable endothelialization of blood microcapillaries, enhancing its hemocompatibility for clinical applications. The architecture of the parallel stacking of the trilayers is based on a central injection for blood and a lateral injection/output for gas which allows significant reduction in shear stress, promoting sustainable endothelialization since cells can be maintained viable for up to 2 weeks after initial seeding in the blood microchannel network. The circular design of curved blood capillaries allows covering a maximal surface area at 4 inch wafer scale, producing high oxygen uptake and carbon dioxide release in each single unit. Read More

View Article and Full-Text PDF

Functional Magnetic Resonance Imaging Signal Variability Is Associated With Neuromodulation in Fibromyalgia.

Neuromodulation 2021 Jul 26. Epub 2021 Jul 26.

Headache and Orofacial Pain Effort (H.O.P.E.), Department of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, Ann Arbor, MI, USA.

Objectives: Although primary motor cortex (M1) transcranial direct current stimulation (tDCS) has an analgesic effect in fibromyalgia (FM), its neural mechanism remains elusive. We investigated whether M1-tDCS modulates a regional temporal variability of blood-oxygenation-level-dependent (BOLD) signals, an indicator of the brain's flexibility and efficiency and if this change is associated with pain improvement.

Materials And Methods: In a within-subjects cross-over design, 12 female FM patients underwent sham and active tDCS on five consecutive days, respectively. Read More

View Article and Full-Text PDF

Extracorporeal carbon dioxide Removal (ECCO R) with the Advanced Organ Support (ADVOS) system in critically ill COVID-19 patients.

Artif Organs 2021 Jul 26. Epub 2021 Jul 26.

Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

Introduction: Disturbed oxygenation is foremost the leading clinical presentation in COVID -19 patients. However, a small proportion also develop carbon dioxide removal problems. The Advanced Organ Support (ADVOS) therapy (ADVITOS GmbH, Munich, Germany) uses a less invasive approach by combining extracorporeal CO -removal and multiple organ support for the liver and the kidneys in a single hemodialysis device. Read More

View Article and Full-Text PDF

Delayed retroperitoneal hemorrhage during extracorporeal membrane oxygenation in COVID-19 patients: A case report and literature review.

World J Clin Cases 2021 Jul;9(19):5203-5210

Department of Critical Care Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China.

Background: Retroperitoneal hemorrhage (RPH) is a rare and severe complication in patients undergoing extracorporeal membrane oxygenation (ECMO). Clinical diagnosis is difficult.

Case Summary: Three cases of RPH patients with corona virus disease-19 (COVID-19) were included in this study. Read More

View Article and Full-Text PDF

Extracorporeal Membrane Oxygenation Used in Acute Respiratory Distress Syndrome with COVID-19: A Systematic Review and Meta-Analysis.

J Saudi Heart Assoc 2021 2;33(2):177-185. Epub 2021 Jul 2.

Department of Cardiology and Vascular Medicine, Faculty of Medicine, Airlangga University-Dr. Soetomo General Hospital, Surabaya, Indonesia.

Introduction: Protective pulmonary mechanical ventilation, higher positive end-expiratory pressure, neuromuscular blockade, prone positioning, and pulmonary recruitment procedures are all strategies in severe COVID-19 cases. Extracorporeal Membrane Oxygenation (ECMO) can be seen as an alternative to traditional treatment in certain patients when conventional therapy fails. We present a study that intends to systematically review and meta-analysis ECMO use in COVID-19 patients. Read More

View Article and Full-Text PDF

Neonatal encephalopathy: Focus on epidemiology and underexplored aspects of etiology.

Semin Fetal Neonatal Med 2021 Jul 15:101265. Epub 2021 Jul 15.

Cerebral Palsy Alliance Research Institute, Faculty of Medicine & Health, The University of Sydney, Sydney, Australia; Grace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, The University of Sydney, Sydney, Australia. Electronic address:

Neonatal Encephalopathy (NE) is a neurologic syndrome in term and near-term infants who have depressed consciousness, difficulty initiating and maintaining respiration, and often abnormal tone, reflexes and neonatal seizures in varying combinations. Moderate/severe NE affects 0.5-3/1000 live births in high-income countries, more in low- and middle-income countries, and carries high risk of mortality or disability, including cerebral palsy. Read More

View Article and Full-Text PDF

Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke.

J Cereb Blood Flow Metab 2021 Jul 26:271678X211033732. Epub 2021 Jul 26.

Wellington Medical Technology Group, Department of Surgery & Anaesthesia, University of Otago, Wellington, New Zealand.

Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is an important determinant of cerebral perfusion, effective BP management could facilitate reperfusion. But how BP should be managed in very early phase of ischemic stroke remains a contentious issue, due to the lack of clear evidence. Read More

View Article and Full-Text PDF

Near-Infrared Light Increases Functional Connectivity with a Non-thermal Mechanism.

Cereb Cortex Commun 2020 19;1(1):tgaa004. Epub 2020 Mar 19.

Department of Biomedical Engineering, City College of New York, New York, NY 10031, USA.

Although techniques for noninvasive brain stimulation are under intense investigation, an approach that has received limited attention is transcranial photobiomodulation (tPBM), the delivery of near-infrared light to the brain with a laser or light-emitting diode directed at the scalp. Here we employed functional magnetic resonance imaging to measure the blood-oxygenation-level-dependent signal in  = 20 healthy human participants while concurrently stimulating their right frontal pole with a near-infrared laser. Functional connectivity with the illuminated region increased by up to 15% during stimulation, with a quarter of all connections experiencing a significant increase. Read More

View Article and Full-Text PDF

Effects of Acute Exposure to Thermal Stress on Cardiorespiratory Function, Skeletal Muscle Oxygenation, and Exercise Performance in Healthy Males.

Int J Environ Res Public Health 2021 Jul 11;18(14). Epub 2021 Jul 11.

Physical Activity and Performance Institute, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.

We investigated the effects of acute thermal stress (30 °C and 40 °C) and ordinary temperature (20 °C) on cardiorespiratory function, skeletal muscle oxygenation, and exercise performance in healthy men. Eleven healthy males (21.5 ± 2. Read More

View Article and Full-Text PDF

[Effect of early mechanical ventilation on the expression of inflammatory factors and prognosis in patients with severe traumatic brain injury].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 Jun;33(6):727-730

Department of Critical Care Medicine, Xinhua Hospital Chongming Branch, Shanghai 202150, China.

Objective: To observe the effect of early mechanical ventilation on the expression of inflammatory factors and prognosis of patients with severe traumatic brain injury (sTBI).

Methods: From January 2017 to December 2020, 138 patients with sTBI admitted to the department of the emergency of Xinhua Hospital Chongming Branch were enrolled. Although some patients were admitted to hospital without acute respiratory failure, their Glasgow coma score (GCS) were less than 8, they bad risk of hypoxia, so early mechanical ventilation was required. Read More

View Article and Full-Text PDF

[Effect of noninvasive positive pressure ventilation and high-flow nasal cannula oxygen therapy on the clinical efficacy of coronavirus disease 2019 patients with acute respiratory distress syndrome].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 Jun;33(6):708-713

Department of Intensive Care Unit, Peking University Third Hospital, Beijing 100191, China.

Objective: To observe the effect of noninvasive positive pressure ventilation (NIPPV) and high-flow nasal cannula oxygen therapy (HFNC) on the prognosis of patients with coronavirus disease 2019 (COVID-19) accompanied with acute respiratory distress syndrome (ARDS).

Methods: A retrospective study was conducted in Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology when authors worked as medical team members for treating COVID-19. COVID-19 patients with pulse oxygen saturation/fraction of inspiration oxygen (SpO/FiO, S/F) ratio < 235, managed by medical teams [using S/F ratio instead of oxygenation index (PaO/FiO) to diagnose ARDS] from February to April 2020 were included. Read More

View Article and Full-Text PDF

[Application value of lung ultrasound in the diagnosis and severity assessment of ventilator-associated pneumonia].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 Jun;33(6):702-707

Department of Critical Care, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China. Corresponding author: Wang Xiaohong, Email:

Objective: To explore the value of bedside lung ultrasound in the early diagnosis and severity assessment of ventilator-associated pneumonia (VAP).

Methods: A prospective observational study was conducted in 60 patients with VAP (VAP group) and 62 patients without VAP (control group) who were admitted to department of intensive care unit of General Hospital of Ningxia Medical University from September 2018 to July 2020. The gender, age and underlying diseases of non-VAP group were matched with VAP group. Read More

View Article and Full-Text PDF

Comparison of the effects of 2 ventilatory strategies using tidal volumes of 6 and 8 ml/kg on pulmonary shunt and alveolar dead space volume in upper abdominal cancers surgery.

Med J Islam Repub Iran 2021 19;35:79. Epub 2021 Jun 19.

Lung Disease Research Center, Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran.

High tidal volume leads to inflammation, and low tidal volume leads to atelectasia and hypoxemia. This study was conducted to compare the effect of 6 mL/kg with positive end-expiratory pressure (PEEP) and 8 mL/kg without PEEP on pulmonary shunt and dead space volume. This clinical trial was done on 36 patients aged 20 to 65 years old with ASA I-II. Read More

View Article and Full-Text PDF

Application of an integrated radio-frequency/shim coil technology for signal recovery in fMRI.

Magn Reson Med 2021 Jul 20. Epub 2021 Jul 20.

Brain Imaging and Analysis Center, Duke University, Durham, North Carolina, USA.

Purpose: Gradient-echo echo-planar imaging (EPI), which is typically used for blood oxygenation level-dependent (BOLD) functional MRI (fMRI), suffers from distortions and signal loss caused by localized B inhomogeneities. Such artifacts cannot be effectively corrected for with the low-order spherical harmonic (SH) shim coils available on most scanners. The integrated parallel reception, excitation, and shimming (iPRES) coil technology allows radiofrequency (RF) and direct currents to flow on each coil element, enabling imaging and localized B shimming with one coil array. Read More

View Article and Full-Text PDF

Sustained Inflation During Chest Compression: A New Technique of Pediatric Cardiopulmonary Resuscitation That Improves Recovery and Survival in a Pediatric Porcine Model.

J Am Heart Assoc 2021 Jul 21:e019136. Epub 2021 Jul 21.

Neonatal Research Unit, Centre for the Studies of Asphyxia and Resuscitation Royal Alexandra Hospital Edmonton Alberta Canada.

Background Chest compression (CC) during sustained inflations (CC+SI) compared with CC with asynchronized ventilation (CCaV) during cardiopulmonary resuscitation in asphyxiated pediatric piglets will reduce time to return of spontaneous circulation (ROSC). Methods and Results Piglets (20-23 days of age, weighing 6.2-10. Read More

View Article and Full-Text PDF

Acute Effects of Dietary Nitrate on Exercise Tolerance, Muscle Oxygenation, and Cardiovascular Function in Patients With Peripheral Arterial Disease.

Int J Sport Nutr Exerc Metab 2021 Jul 20:1-12. Epub 2021 Jul 20.

Radboud University Medical Center.

Previous studies have used supplements to increase dietary nitrate intake in clinical populations. Little is known about whether effects can also be induced through vegetable consumption. Therefore, the aim of this study was to assess the impact of dietary nitrate, through nitrate-rich vegetables (NRV) and beetroot juice (BRJ) supplementation, on plasma nitrate and nitrite concentrations, exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease. Read More

View Article and Full-Text PDF

Evaluating the Effects of Subnormothermic Perfusion with AP39 in a Novel Blood-Free Model of Ex Vivo Kidney Preservation and Reperfusion.

Int J Mol Sci 2021 Jul 2;22(13). Epub 2021 Jul 2.

Department of Microbiology and Immunology, Western University, London, ON N6A 5C1, Canada.

The use of blood for normothermic and subnormothermic kidney preservation hinders the translation of these approaches and promising therapeutics. This study evaluates whether adding hydrogen sulfide donor AP39 to Hemopure, a blood substitute, during subnormothermic perfusion improves kidney outcomes. After 30 min of renal pedicle clamping, porcine kidneys were treated to 4 h of static cold storage (SCS-4 °C) or subnormothermic perfusion at 21 °C with Hemopure (H-21 °C), Hemopure + 200 nM AP39 (H200nM-21 °C) or Hemopure + 1 µM AP39 (H1µM-21 °C). Read More

View Article and Full-Text PDF

The Role of Deep Hypothermia in Cardiac Surgery.

Int J Environ Res Public Health 2021 Jul 1;18(13). Epub 2021 Jul 1.

Department of Anaesthesiology and Intensive Care, Medical University of Silesia, 40-752 Katowice, Poland.

Hypothermia is defined as a decrease in body core temperature to below 35 °C. In cardiac surgery, four stages of hypothermia are distinguished: mild, moderate, deep, and profound. The organ protection offered by deep hypothermia (DH) enables safe circulatory arrest as a prerequisite to carrying out cardiac surgical intervention. Read More

View Article and Full-Text PDF

Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients.

Cochrane Database Syst Rev 2021 Jul 19;7:CD013307. Epub 2021 Jul 19.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Background: Delirium is an acute neuropsychological disorder that is common in hospitalised patients. It can be distressing to patients and carers and it is associated with serious adverse outcomes. Treatment options for established delirium are limited and so prevention of delirium is desirable. Read More

View Article and Full-Text PDF

Transition to Ductal Stenting for Single Ventricle Patients Led to Improved Survival: An Institutional Case Series.

World J Pediatr Congenit Heart Surg 2021 Jul;12(4):518-526

Congenital Heart Surgery Research and Training Program, 22957Duke University Medical Center, Durham, NC, USA.

Background: The use of systemic-to-pulmonary shunts (SPS) in neonates with single ventricle heart defects and ductal-dependent pulmonary blood flow (ddPBF) was historically associated with high morbidity and mortality at our center. As a result, we transitioned to the preferential use of ductus arteriosus stents (DS) when feasible. This report describes our initial results with this strategy. Read More

View Article and Full-Text PDF

Extracorporeal Membrane Oxygenation Complications in Heparin- and Bivalirudin-Treated Patients.

Crit Care Explor 2021 Jul 13;3(7):e0485. Epub 2021 Jul 13.

Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.

Extracorporeal membrane oxygenation is a potentially life-saving intervention in refractory cardiopulmonary failure, but it requires anticoagulation to prevent circuit thromboses, which exposes the patient to hemorrhagic complications. Heparin has traditionally been the anticoagulant of choice, but the direct thrombin inhibitor bivalirudin is routinely used in cases of heparin-induced thrombocytopenia and has been suggested as a superior choice. We sought to examine the timing of hemorrhagic and thrombotic complications after extracorporeal membrane oxygenation cannulation and to compare the rates of such complications between patients anticoagulated with heparin versus bivalirudin. Read More

View Article and Full-Text PDF

Use of rotational thromboelastometry to predict hemostatic complications in pediatric patients undergoing extracorporeal membrane oxygenation: A retrospective cohort study.

Res Pract Thromb Haemost 2021 Jul 14;5(5):e12553. Epub 2021 Jul 14.

Department of Pediatric Hematology Erasmus Medical Center - Sophia Children's Hospital Rotterdam The Netherlands.

Background: The incidence of hemostatic complications in pediatric patients undergoing extracorporeal membrane oxygenation (ECMO) is high. The optimal anticoagulation strategy in children undergoing ECMO is unknown.

Objectives: To study the association between hemostatic complications, coagulation tests, and clinical parameters in pediatric patients undergoing ECMO and their effect on survival. Read More

View Article and Full-Text PDF

Neurological Complications of Veno-Arterial Extracorporeal Membrane Oxygenation: A Retrospective Case-Control Study.

Front Med (Lausanne) 2021 1;8:698242. Epub 2021 Jul 1.

Department of Critical Care Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

To explore the epidemiology, clinical features, risk indicators, and long-term outcomes of neurological complications caused by veno-arterial extracorporeal membrane oxygenation (V-A ECMO). We retrospectively analyzed 60 adult patients who underwent V-A ECMO support in our unit from February 2012 to August 2020. These patients were separated into the neurological complications group (NC group) and the non-neurological complications group (nNC group). Read More

View Article and Full-Text PDF