Front Immunol 2021 4;12:727457. Epub 2021 Nov 4.
MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
The burden of infections on an individual and public health is profound. Many observational studies have shown a link between infections and the pathogenesis of disease; however a greater understanding of the role of host genetics is essential. Children from the longitudinal birth cohort, the Avon Longitudinal Study of Parents and Children, had 14 antibodies measured in plasma at age 7: Alpha-casein protein, beta-casein protein, cytomegalovirus, Epstein-Barr virus, feline herpes virus, , herpes simplex virus 1, influenza virus subtype H1N1, influenza virus subtype H3N2, measles virus, , Theiler's virus, , and SAG1 protein domain, a surface antigen of measured for greater precision. Read More