Am J Physiol Heart Circ Physiol 2021 Apr 16. Epub 2021 Apr 16.
Department of Kinesiology, University of Virginia, Charlottesville, VA; Department of Kinesiology & Health, Rutgers University, New Brunswick, NJ; Division of Endocrinology, Metabolism & Nutrition; Rutgers University, New Brunswick, NJ; New Jersey Institute for Food, Nutrition and Health, Rutgers University, New Brunswick, NJ; Institute of Translational Medicine and Science, Rutgers University, New Brunswick, NJ, United States.
Adults with metabolic syndrome (MetS) have increased fasting arterial stiffness and altered central hemodynamics that contribute, partly, to increased cardiovascular disease (CVD) risk. Although insulin affects aortic wave reflections in healthy adults, the effects in individuals with MetS are unclear. We hypothesized that insulin stimulation would reduce measures of pressure waveforms and hemodynamics in people with MetS. Read More