104,549 results match your criteria bladder symptoms


Prediagnostic Serum 25-Hydroxyvitamin D and Mortality Among Bladder Cancer Patients in the Janus Serum Bank Cohort.

Clin Epidemiol 2021 14;13:801-811. Epub 2021 Sep 14.

Department of Research, Cancer Registry of Norway, Oslo, Norway.

Purpose: Circulating 25-hydroxyvitamin D (25(OH)D) is inversely associated with overall cancer mortality and selected cancers, while for urothelial bladder cancer (BC) this relationship is unclear. We aimed to examine the association between 25(OH)D and BC mortality.

Materials And Methods: We used prediagnostic serum from 378 BC cases within the population-based Janus Cohort. Read More

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September 2021

The Anatomical Relationships in the Space of Retzius for Penile Implants: An MRI Analysis.

J Sex Med 2021 Sep 18. Epub 2021 Sep 18.

Male Sexual and Reproductive Medicine Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. Electronic address:

Background: The 3-piece inflatable penile prosthesis includes an easy-to-use pump and fluid filled reservoir which is placed in either the space of Retzius (SOR) or in an alternative ectopic location. Reservoir placement in the SOR is a blind procedure despite the SOR being surrounded by many critical structures. To date only a handful of cadaveric studies have described the relevant anatomy. Read More

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September 2021

Long-term functional and psychosocial outcome in adolescents and young adults treated for lower urinary tract dysfunction in childhood.

J Pediatr Urol 2021 Sep 3. Epub 2021 Sep 3.

Department of Medical Psychology, Radboud University Medical Center, Amalia Children's Hospital, Nijmegen, the Netherlands. Electronic address:

Background: Lower urinary tract dysfunction (LUTD) in childhood might affect lower urinary tract function and psychological wellbeing later in life. This study presents long-term functional outcome, psychological outcome and quality of life (QOL) of adolescents and young adults treated for childhood LUTD compared to healthy age-matched controls. In addition, association with past treatment outcomes is evaluated. Read More

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September 2021

Time-Related Changes in Patient Reported Bladder Symptoms and Satisfaction after Spinal Cord Injury.

J Urol 2021 Sep 22:101097JU0000000000002228. Epub 2021 Sep 22.

University of Utah, Salt Lake City, Utah, USA.

Purpose: Increased time after spinal cord injury (SCI) is associated with a migration to bladder managements with higher morbidity such as indwelling catheter (IDC). Still it is unclear how this affects bladder-related quality of life (QoL). We hypothesized that time from injury (TFI) would be associated with changes in bladder management, symptoms, and satisfaction. Read More

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September 2021

Mirabegron improves the irritative symptoms caused by BCG immunotherapy after transurethral resection of bladder tumors.

Cancer Med 2021 Sep 21. Epub 2021 Sep 21.

Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.

Background: This study aims to explore the efficacy and safety of mirabegron in treating irritative symptoms induced by intravesical immunotherapy with Bacillus Calmette-Guerin (BCG) after transurethral resection of bladder tumors (TURBT).

Methods: A total of 160 patients subjected to TURBT was randomly divided into the mirabegron group and placebo group with 80 patients in each group. Then, the patients were administered 25 mg mirabegron or placebo daily, starting the first day after BCG infusion. Read More

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September 2021

Live surgery of colorectal endometriosis broadcasted from a surgeon's routine operating theater is not associated with higher complications rate.

Acta Obstet Gynecol Scand 2021 Sep 21. Epub 2021 Sep 21.

Department of Surgery, Rouen University Hospital, Rouen, France.

Introduction: Although live surgeries are routinely included in surgical congress programs, they are the subject of an ongoing debate in terms of patient safety and teaching value. The goal of our study was to assess the risk of postoperative complications related to live surgery broadcast from the surgeon's routine theater, in patients managed for deep endometriosis infiltrating the digestive tract.

Material And Methods: We report a retrospective comparative study, enrolling women managed for colorectal endometriosis by a gynecologic surgeon, from September 2013 to March 2020 in two referral centers. Read More

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September 2021

Relationships between overactive bladder and cerebral white matter hyperintensity in outpatients at a memory clinic.

Geriatr Gerontol Int 2021 Sep 20. Epub 2021 Sep 20.

Department of Community Healthcare & Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Aim: Cerebral small vessel disease and lower urinary tract symptoms are common in older people. However, the association between white matter hyperintensity (WMH) and overactive bladder (OAB) is not fully understood. We aimed to identify the relationship between WMH and OAB. Read More

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September 2021

Prospective Randomized Controlled Trial Comparing Adjuvant Chemotherapy vs. No Chemotherapy for Patients with Carcinoma of Gallbladder Undergoing Curative Resection.

J Gastrointest Surg 2021 Sep 20. Epub 2021 Sep 20.

Department of Radiotherapy, Maulana Azad Medical College, New Delhi, India.

Background: Gallbladder carcinoma (GBC) has a dismal prognosis even after curative resection. The objective of the study was to evaluate the effect of adjuvant chemotherapy in patients with GBC undergoing curative resection in a randomized control trial (RCT).

Methods: A single-center open-labeled prospective RCT was done from January 2012 to June 2018. Read More

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September 2021

Poor clinical guideline adherence and inappropriate testing for incident lower urinary tract symptoms associated with benign prostatic hyperplasia.

Prostate Cancer Prostatic Dis 2021 Sep 20. Epub 2021 Sep 20.

Center for Male Health, Loyola University Medical Center, Maywood, IL, USA.

Background: The American Urological Association makes recommendations for evaluation and testing for lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH) to help primary care providers and specialists identify LUTS/BPH and harmful related conditions including urinary retention and prostate or bladder cancer. Our understanding of provider adherence to these Guidelines is limited to single-site or nonrepresentative settings.

Methods: We analyzed two insurance claims databases: the Optum de-identified Clinformatics Data Mart database for privately insured males aged 40-64 years (N ≈ 1,650,900 annually) and the Medicare 5% Sample for males aged ≥65 years (N ≈ 546,000 annually). Read More

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September 2021

Pubic symphysis osteomyelitis with associated vesico-symphyseal fistula: a difficult diagnosis.

BMJ Case Rep 2021 Sep 20;14(9). Epub 2021 Sep 20.

Interventional Radiology, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA.

Pubic symphysis osteomyelitis is an infectious complication that rarely arises in men who have undergone treatment for prostate cancer. This process may more rarely arise from a fistulous tract between the pubic symphysis and the urinary tract. In this case report, we discuss the most common clinical presentations and laboratory findings that lead to the diagnosis of this disease process, as well as the role of MRI and other imaging modalities in confirmation of the diagnosis. Read More

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September 2021

Peripheral nervous system electrodiagnostic abnormalities in predominantly Hispanic Multiple Sclerosis patients.

Mult Scler Relat Disord 2021 Sep 4;56:103254. Epub 2021 Sep 4.

Department of Neurology, University of Miami, Miami, FL, USA, 1120 NW 14(th) Street, 13th Floor, Miami FL 33136, USA.

Background: Peripheral nervous system (PNS) abnormalities in Multiple Sclerosis (MS) have been reported in case reports and small case series over the past several decades. Little is known, however, about the prevalence of electrodiagnostic abnormalities in patients with MS, including not only demyelinating neuropathies such as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) but also axonal peripheral neuropathy and sympathetic dysfunction.

Methods: This is an observational, cross-sectional study with the objective of identifying the prevalence of the electrodiagnostic abnormalities in predominantly Hispanic MS patients in Miami, Florida. Read More

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September 2021

The Evaluation of Cases with Ocular Complications due to Bacillus Calmette-Guerin (BCG) Treatment using the Pool Analysis Method.

Semin Ophthalmol 2021 Sep 20:1-6. Epub 2021 Sep 20.

Department of Ophthalmology, University of Health Science, Haseki Training and Research Hospital, Istanbul, Turkey.

Objective: The aim of this study was to investigate cases with ocular complications associated with intravesical BCG therapy in terms of clinical features, demographic features and type of ocular involvement.

Methods: PubMed database was scanned for relevant publications using the keywords. Thirty-seven publications and 147 reported cases were identified related to the development of ocular complications due to intravesical BCG treatment. Read More

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September 2021

Identification of hub genes in bladder cancer based on weighted gene co-expression network analysis from TCGA database.

Cancer Rep (Hoboken) 2021 Sep 20:e1557. Epub 2021 Sep 20.

College of Life Sciences, Xinyang Normal University, Xinyang, China.

Background: Muscular invasive bladder cancer (MIBC) is a common malignant tumor in the world. Because of their heterogeneity in prognosis and response to treatment, biomarkers that can predict survival or help make treatment decisions in patients with MIBC are essential for individualized treatment.

Aim: We aimed to integrate bioinformatics research methods to identify a set of effective biomarkers capable of predicting, diagnosing, and treating MIBC. Read More

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September 2021

Cystic dilatation of umbilical cord associated with patent urachus.

Ginekol Pol 2021 ;92(8):595-596

2nd Department of Gynecology and Obstetrics, Wroclaw Medical University, Wroclaw, Poland.

An urachus is a remnant of allantois in embryo development constituting a connection between the dome of the bladder and umbilicus. It develops on day 16 after conception and closes during the pregnancy to form the median umbilical ligament. Patent urachus results from a failure in closing its lumen in 10-12 gestational weeks. Read More

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January 2021

Paraganglioma of Urinary Bladder: An Uncommon Entity in Uropathology.

Cureus 2021 Aug 17;13(8):e17265. Epub 2021 Aug 17.

Urology, Royal Hospital, Muscat, OMN.

Paraganglioma of the urinary bladder is a rare neoplasm. It may be functional, secreting catecholamines, or nonfunctional. Clinically and histopathologically, it has the potential to be misdiagnosed as a more common urothelial carcinoma, especially in nonfunctional cases. Read More

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Mycoplasma pneumoniae Associated Acute Transverse Myelitis: An Atypical Clinical Presentation in an Adolescent Child.

Cureus 2021 Aug 17;13(8):e17259. Epub 2021 Aug 17.

Pediatric Critical Care Medicine, Nemours Children's Hospital, Orlando, USA.

We report an atypical case of a 15-year-old pediatric patient diagnosed with Mycoplasma pneumoniaeassociated acute transverse myelitis (ATM). The patient had no prodromal or pulmonary symptoms that are commonly associated with mycoplasma infection. Yet, the patient exhibited acute bilateral lower extremity paralysis, paresthesia, decreased sensation at the level of T11 and below, bowel and bladder dysfunction, and thrombocytopenia. Read More

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COVID-19, Necrotizing Pancreatitis, and Abdominal Compartment Syndrome: A Perfect Cytokine Storm?

Cureus 2021 Aug 16;13(8):e17230. Epub 2021 Aug 16.

Internal Medicine, St. Vincent Charity Medical Center, Cleveland, USA.

Coronavirus disease 2019 (COVID-19) induces a dysregulated immune response, leading to a drastic elevation of proinflammatory cytokines. This cytokine storm has the potential to aggravate any prior ongoing inflammation. Moreover, acute pancreatitis can cause local necrosis, thereby causing extensive abdominal inflammation. Read More

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Diagnostic Tests for Female Bladder Outlet Obstruction: A Systematic Review from the European Association of Urology Non-neurogenic Female LUTS Guidelines Panel.

Eur Urol Focus 2021 Sep 16. Epub 2021 Sep 16.

Department of Urology, Freeman Hospital, Newcastle-upon-Tyne, UK.

Context: Female bladder outlet obstruction (fBOO) is a relatively uncommon condition compared with its male counterpart. Several criteria have been proposed to define fBOO, but the comparative diagnostic accuracy of these remains uncertain.

Objective: To identify and compare different tests to diagnose fBOO through a systematic review process. Read More

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September 2021

A Case of Psoas Muscle Abscess With Hematuria, Detected Initially by Point-of-Care Ultrasound in the Emergency Department.

J Emerg Med 2021 Sep 14. Epub 2021 Sep 14.

Department of Emergency Medicine, Cathay General Hospital, Taipei, Taiwan.

Background: Psoas muscle abscess (PMA) is a collection of pus in the psoas muscle. It is considered a rare clinical entity and is often misdiagnosed due to highly vague symptoms. We report that point-of-care ultrasound (POCUS) serves as a useful and noninvasive tool for early detection of PMA. Read More

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September 2021

Seizures: A Rare Presentation of Autonomic Dysreflexia in a Young Adult with Complete Spinal Cord Injury.

J Emerg Med 2021 Sep 14. Epub 2021 Sep 14.

University of Missouri-Kansas City School of Medicine, Kansas City, Missouri; University of Kansas-School of Medicine, Kansas City, Kansas; Division of Pediatric Emergency Medicine, Children's Mercy Hospital, Kansas City, Missouri.

Background: Autonomic dysreflexia (AD) is a common complication for individuals with cervical or upper-mid thoracic spinal cord injury (SCI). It is a life-threatening emergency; however, it is rarely encountered by many emergency physicians, thus, ongoing awareness of the topic is necessary.

Case Report: An 18-year-old man with cervical spinal cord injury presented to the Emergency Department with headache, nausea, elevated blood pressure, and seizures. Read More

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September 2021

Spontaneous bladder rupture following non traumatic vaginal delivery in a multiparous woman: A rare case report.

Int J Surg Case Rep 2021 Aug 27;87:106349. Epub 2021 Aug 27.

Obstetrics and Gynecology Department, Univesity Hospital Center Ibn Rochd, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Introduction: Spontaneous bladder rupture SBR is a rare condition and often missed diagnosis, especially after a nontraumatic vaginal delivery.

Case Presentation: A 34-year-old patient who had a nontraumatic vaginal delivery presented to the emergency room 7 days later with acute abdomen and anuria. Computed tomography showed free fluid in the peritoneal cavity. Read More

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Forgotten DJ stent presenting with emphysematous pyelonephritis: A life threatening complication.

Int J Surg Case Rep 2021 Sep 15;87:106405. Epub 2021 Sep 15.

Department of Surgery, Patan Hospital, Patan Academy of Health Sciences, Lalitpur, Nepal.

Introduction: Emphysematous pyelonephritis (EPN) is an uncommon suppurative infection of renal parenchyma and perirenal tissue characterized by production of gas within renal parenchyma, collecting system or perinephric tissue.

Case Presentation: We report a case of young non diabetic female with past history of extracorporeal shock wave lithotripsy (ESWL) who presented with intermittent lower abdominal pain, dysuria and left lower limb swelling. Abdomen examination was notable for tenderness at left iliac fossa and fullness at left renal angle. Read More

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September 2021

Heterotopic Ossifications after Fractures of the Anterior Pelvic Segment: Overview of Morphology and Clinical Correlations.

Acta Chir Orthop Traumatol Cech 2021 ;88(4):253-259

Centre for Integrated Studies of the Pelvis, Third Faculty of Medicine, Charles University, Prague.

PURPOSE OF THE STUDY In certain patients after treated pelvic fractures, heterotopic ossifications can be observed in the area of the pubic bone, which protrude ventrally, and often also laterally and distally into surrounding soft tissues of the groin or even medially into the proximal thigh. These ossifications are shaped like sharp spikes of various lengths, which is why the authors refer to them as "spicules". In some patients, these ossifications are also associated with pain. Read More

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September 2021

Female chronic posterior urethritis is underestimated in patients with lower urinary tract symptoms.

Transl Androl Urol 2021 Aug;10(8):3456-3464

Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, China.

Background: As one of the causes of urethral symptoms, female chronic posterior urethritis is a common and distressing disease; however, it is often neglected and misdiagnosed as overactive bladder (OAB) or interstitial cystitis/bladder pain syndrome (IC/BPS). Currently, little is known about the urothelium and lamina propria of the bladder neck and proximal urethra. Thus, identifying urethral lesions is necessary for the diagnosis and treatment of female chronic posterior urethritis. Read More

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Young age increases the risk of lymph node positivity but improves prognosis in patients with bladder cancer treated via cystectomy: a population-based study.

Transl Androl Urol 2021 Aug;10(8):3375-3385

Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Background: Age and lymph node positivity are significant prognostic indicators in patients with bladder cancer. This study aimed to investigate the impact of age on lymph node positivity and bladder cancer outcomes.

Methods: Patients with bladder cancer who underwent cystectomy with at least one lymph node examined between 2004 and 2015 were identified from the Surveillance, Epidemiology, and End Results database. Read More

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Terminal augmented ureteroplasty with bladder onlay flap technique for recurrent distal ureteral stricture after ureteroneocystostomy: an initial case series.

Transl Androl Urol 2021 Aug;10(8):3332-3339

Department of Urology, Peking University First Hospital, Beijing, China.

Background: Bladder flap has been shown to be a feasible treatment for distal ureteral stenosis; this technique has been improved such that it can be used to address complex urinary tract obstructions. The purpose of the present study was to describe a surgical technique of ureteroplasty with a bladder onlay flap, which consists of a nontransecting and terminal augmented anastomosis, for repairing recurrent distal strictures of the ureter.

Methods: We retrospectively reviewed 6 patients who underwent this procedure between May 2018 and November 2019. Read More

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Proteomic analysis exploring the mechanism of bladder fibrosis induced by ketamine using a rat model.

Transl Androl Urol 2021 Aug;10(8):3300-3311

Department of Urology, Xiangya Hospital, Central South University, Changsha, China.

Background: Long-term abuse of ketamine can cause irreversible bladder fibrosis, but the mechanism of bladder fibrosis is still under investigation. This study aims to explore the mechanism of bladder fibrosis utilizing proteomic analysis in a rat model.

Methods: After building a rat model, hematoxylin and eosin (HE) staining, Masson's trichrome staining, and western blotting (WB) of collagen I were used to assess bladder pathology and fibrosis in a rat model. Read More

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The impact of changing risk thresholds on the number of people in England eligible for urgent investigation for possible cancer: an observational cross-sectional study.

Br J Cancer 2021 Sep 16. Epub 2021 Sep 16.

University of Exeter Medical School, College of Medicine & Health, St Luke's Campus, Magdalen Road, Exeter, UK.

Background: Expediting cancer diagnosis may be achieved by targeted decreases in referral thresholds to increase numbers of patients referred for urgent investigation.

Methods: Clinical Practice Research Datalink data from England for 150,921 adults aged ≥40 were used to identify participants with features of possible cancer equating to risk thresholds ≥1%, ≥2% or ≥3% for breast, lung, colorectal, oesophago-gastric, pancreatic, renal, bladder, prostatic, ovarian, endometrial and laryngeal cancers.

Results: The mean age of participants was 60 (SD 13) years, with 73,643 males (49%). Read More

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September 2021

Quick-Wee versus bladder stimulation to collect midstream urine from precontinent infants under 1 year of age: a study protocol for a randomised controlled trial (ES.Stimquick.U).

BMJ Open 2021 Sep 16;11(9):e046324. Epub 2021 Sep 16.

Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.

Introduction: Urinary tract infections occur in around 1%-4% of boys and 3%-8% of girls under 2 years old. Diagnosis is difficult because of non-specific symptoms and the risk of urine analysis contamination depending on the sampling method used for precontinent infants. The American Academy of Pediatrics recommend transurethral catheterisation and suprapubic aspiration because of a low contamination rate but these techniques are invasive. Read More

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September 2021

Focused Ultrasound Examination of Canine and Feline Emergency Urinary Tract Disorders.

Vet Clin North Am Small Anim Pract 2021 Sep 14. Epub 2021 Sep 14.

Clinical Science and Services, The Royal Veterinary College, The University of London, Hawkshead Lane, Hatfield, AL9 7TA.

This article discusses the usefulness of ultrasound examinations in the management of the patient with an emergency urinary tract disorder. It discusses the use of previously described point-of-care ultrasound protocols such as the abdominal focused assessment with sonography for trauma, triage, and tracking protocol in the unstable azotemic patient. Point-of-care ultrasound examination can help direct investigations and expedite the diagnosis of specific causes of azotemia. Read More

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September 2021