196,217 results match your criteria bladder


Demographic Differences and Disparities in the Misdiagnosis of Interstitial Cystitis/Bladder Pain Syndrome in a National Cohort of VA Patients.

Urology 2021 Aug 1. Epub 2021 Aug 1.

Department of Surgery, Division of Urology, Cedars-Sinai Medical Center, Los Angeles, California.

Objectives: To explore association between misdiagnosis of IC/BPS and demographics. Interstitial cystitis/bladder pain syndrome (IC/BPS) is associated with significant diagnostic uncertainty, resulting in frequent misdiagnosis as there is little known about the potential impact of key demographic factors.

Methods: All patients in the VA system between 1999-2016 were identified by ICD-9/10 codes for IC/BPS (595. Read More

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Standard Versus Hypofractionated Radiation Therapy for Bladder Cancer: New Insights, but Questions Remain.

Int J Radiat Oncol Biol Phys 2021 Sep;111(1):113-116

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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September 2021

Evidence for Roux-en-Y Pancreatic Duct Drainage Versus Standard Anastomosis in Pancreatic Transplantation.

Pancreas 2021 Aug 3. Epub 2021 Aug 3.

From the Nuffield Department of Surgical Sciences Somerville College, University of Oxford, Oxford, United Kingdom Renal, Transplant and Urology, Oxford Transplant Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom Transplant Department, Guy's and St Thomas' NHS Foundation Trust, London Department of Surgery, University of Cambridge Cambridge Biomedical Research Centre, National Institute of Health Research Cambridge Biomedical Research Centre NIHR Blood and Transplant Research Unit, NIHR Blood and Transplant Research Unit, University of Cambridge, Cambridge, United Kingdom.

Objectives: Pancreatic transplantation is usually performed simultaneously with renal transplantation in the setting of end-stage nephropathy and type 1 diabetes. Surgical methods for dealing with exocrine secretions include bladder drainage, direct duodenojejunostomy and Roux-en-Y (ReY) enteric drainage. Roux-en-Y may confer an advantage over duodenojejunostomy because it distances enteric content from the transplant duodenal anastomosis. Read More

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Correlations between bladder wall thickness and clinical manifestations in female patients with detrusor underactivity and detrusor overactivity-with-detrusor underactivity.

J Chin Med Assoc 2021 Jul 30. Epub 2021 Jul 30.

Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC Department of Urology, College of Medicine Shu-Tien Urological Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.

Background: Among female patients with lower urinary tract symptoms, detrusor underactivity (DU) and detrusor overactivity-with-detrusor underactivity (DO-DU) are two common diagnoses. Here, we investigated the correlations between bladder wall thickness (BWT) and clinical manifestations of the two diagnoses.

Methods: From 2011 to 2016, female patients with DU or DO-DU, diagnosed at our institute, were recruited. Read More

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Clinical features, laboratory and radiological findings of patients with acute inflammatory myelopathy following COVID-19 infection: a narrative review.

Am J Phys Med Rehabil 2021 Aug 3. Epub 2021 Aug 3.

Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, Bhubaneswar, India.

Abstract: The objective of this review is to analyze the existing data on acute inflammatory myelopathies (AIM) associated with COVID-19 infection, which were reported globally in 2020. PubMed, CENTRAL, MEDLINE, and online publication databases were searched. Thirty-three AIM cases (among them, seven cases had associated brain lesions) associated with COVID-19 infection were reported. Read More

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Enhancing the Sensitivity of the Virus BioResistor by Overoxidation: Detecting IgG Antibodies.

Anal Chem 2021 Aug 4. Epub 2021 Aug 4.

Department of Chemistry, University of California, Irvine, Irvine, California 92697, United States.

The Virus BioResistor (VBR) is a biosensor capable of rapid and sensitive detection of small protein disease markers using a simple dip-and-read modality. For example, the bladder cancer-associated protein DJ-1 (22 kDa) can be detected in human urine within 1.0 min with a limit of detection (LOD) of 10 pM. Read More

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Outcomes of nine cats with urinary retention after sacrocaudal luxation managed with long-term urinary diversion.

Vet Surg 2021 Aug 4. Epub 2021 Aug 4.

Surgical Unit, Centre Hospitalier Vétérinaire St Martin, Fillières, France.

Objective: To document the outcomes of cats with urinary retention (UR) after sacrocaudal luxation (SCL) and managed with a long-term cystostomy (LTC).

Study Design: Short case series.

Animals: Nine client-owned cats with SCL and subsequent UR. Read More

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Prevalence and predictors of bowel dysfunction in a large multiple sclerosis outpatient population: an Italian multicenter study.

J Neurol 2021 Aug 4. Epub 2021 Aug 4.

MS Center-I Division of Neurology, Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italia, piazza Miraglia, 2, 80138, Naples, Italy.

Introduction: Bowel dysfunction (BD) is reported as a common and disabling symptom in multiple sclerosis (MS) patients. To date, no studies have explored the prevalence of these symptoms in a large multicenter outpatient setting. The aims of the present study are to assess: (i) the prevalence of BD in a large multicenter Italian MS population, and (ii) the correlation between clinico-demographic variables and the severity of BD. Read More

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GM-CSF-producing lymphocytes in tumor-draining lymph nodes of patients with bladder cancer.

Eur Cytokine Netw 2021 Mar;32(1):1-7

Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Bladder cancer (BC) is the tenth common cancer worldwide. Despite progress in treatment and the use of chemotherapoeutic drugs, the survival rate of BC patients is still low. Manipulation of the immune system was recently introduced as an interesting alternative treatment for this immunogenic cancer with fewer side effects. Read More

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MP44-09 UNDERSTANDING PRUNE BELLY SYNDROME AT SINGLE CELL RESOLUTION.

J Urol 2021 Sep 4;206(Suppl 3):e796. Epub 2021 Aug 4.

Introduction And Objective: Prune Belly Syndrome (PBS) is characterized by bladder dysmyogenesis, yielding a dysfunctional compliant thick wall with excess collagen deposition. To dissect the cellular heterogeneity and gene expression networks altered in PBS, we report the cell type composition and transcriptional activity of PBS human bladder by using single cell RNA sequencing (scRNA-seq).

Methods: Using IRB-approved methods, bladder dome from 2 PBS and 6 non-PBS control (CO) males underwent fresh single-cell digestion. Read More

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September 2021

[Complications related to pessary use in the treatment of female pelvic organ prolapse].

Ned Tijdschr Geneeskd 2021 07 22;165. Epub 2021 Jul 22.

Rivas Zorggroep, locatie Beatrixziekenhuis, afd. Gynaecologie en Verloskunde, Gorinchem.

Pelvic organ prolapse affects 40% of women over 40 years. Pessaries are often used as a first-line treatment and give high patient satisfaction. Complications of pessaries are rare, but vaginal erosions can lead to adhesions, haemorrhage, impaction and migration. Read More

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Bi-layer silk fibroin skeleton and bladder acellular matrix hydrogel encapsulating adipose-derived stem cells for bladder reconstruction.

Biomater Sci 2021 Aug 4. Epub 2021 Aug 4.

Department of Urology, the Third Medical Centre, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.

A scaffold, constructed from a bi-layer silk fibroin skeleton (BSFS) and a bladder acellular matrix hydrogel (BAMH) encapsulated with adipose-derived stem cells (ASCs), was developed for bladder augmentation in a rat model. The BSFS, prepared from silk fibroin (SF), had good mechanical properties that allowed it to maintain the scaffold shape and be used for stitching. The prepared BAM was digested by pepsin and the pH was adjusted to harvest the BAMH that provided an extracellular environment for the ASCs. Read More

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Combination of AST to ALT and neutrophils to lymphocytes ratios as predictors of locally advanced disease in patients with bladder cancer subjected to radical cystectomy: Results from a single-institutional series.

Urologia 2021 Aug 4:3915603211035191. Epub 2021 Aug 4.

IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.

Background: Bladder cancer (BC) staging is challenging. There is an important need for available and affordable predictors to assess, in combination with imaging, the presence of locally-advanced disease.

Objective: To determine the role of the De Ritis ratio (DRR) and neutrophils to lymphocytes ratio (NLR) in the prediction of locally-advanced disease defined as the presence of extravescical extension (pT ⩾ 3) and/or lymph node metastases (LNM) in patients with BC treated with radical cystectomy (RC). Read More

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Evaluation of the Clinical Efficacy and Complications of Duloxetine in Comparison to Solifenacin in the Treatment of Overactive Bladder Disease in Women: A Randomized Clinical Trial.

Urol J 2021 Aug 3. Epub 2021 Aug 3.

Department of Urology, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Purpose: SNRIs (serotonin and norepinephrine reuptake inhibitors) like duloxetine are known to have role in the treatment of anxiety disorder and stress urinary incontinence. According to the correlation of anxiety disorder and overactive bladder, this study aimed to evaluate the clinical efficacy and complications of duloxetine (SNRI) as a medication in the treatment of overactive bladder in the female patients. We were interested to know the probable therapeutic effect and side effects of duloxetine in overactive bladder. Read More

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Characterization of Sonic Hedgehog/Gli1 Signal Expression in Human Ureter Either Un-Stented or Fitted with Double-Pigtail Stent or a Thread.

Res Rep Urol 2021 26;13:529-533. Epub 2021 Jul 26.

Laboratory of Anatomocytopathology, Laboratoire Léonard de Vinci, Chambray-lès-Tours, 37170, France.

Introduction: The Sonic Hedgehog/Gli1 signal is involved in smooth muscle activity. An experiment showed that the double-pigtail stent caused ureteral inflammation and decreased Gli1 expression in smooth muscle cells. The innovative pigtail-suture stent (JFil or MiniJFil) with a thin 0. Read More

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Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion.

Urol Case Rep 2021 Nov 14;39:101781. Epub 2021 Jul 14.

Department of Urology, Royal Prince Alfred Hospital, Sydney, Australia.

A 36-year-old male patient is referred for urology review for haematuria following cyclophosphamide and mesna administration for allogeneic stem cell transplant for treatment of acute lymphoblastic leukaemia. Severe haematuria continued despite multiple interventions including continuous bladder irrigation and cystoscopic fulguration, with formation of consolidated clot in the bladder. A successful cystotomy for removal of clot and initiation of alum was performed, leading to resolution of haematuria. Read More

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November 2021

Prostate cancer featuring a unique progression pattern: A case of prominent direct perineal invasion without definite metastasis.

Urol Case Rep 2021 Nov 13;39:101779. Epub 2021 Jul 13.

Department of Urology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.

Locally advanced prostate cancer can extend into the pelvis, and can also invade the bladder and rectum. We encountered a patient with prostate cancer that exhibited severe local invasion, protruding into the perineum. Distant metastasis was absent, despite the large tumor size. Read More

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November 2021

Bladder stone secondary to prostatic urethral lift (PUL) for benign prostatic hyperplasia (BPH).

Authors:
JiHun Kang

Urol Case Rep 2021 Nov 14;39:101777. Epub 2021 Jul 14.

Department of Urology, Chinjukorea Hospital, Dongjinro 2, Chinju City, 52726, South Korea.

Unlike other cavitating prostatic surgeries, prostatic urethral lift (PUL) has the advantage of being noninvasive and having fewer complications. In addition, PUL can be performed under local anesthesia and is can be performed on patients with various comorbidities. However, serious complications have been reported in some patients, so caution is required. Read More

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November 2021

Lumbar disc herniation presenting with fecal incontinence without radiculopathy: A case report.

Surg Neurol Int 2021 19;12:353. Epub 2021 Jul 19.

Department of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Larissa, Greece.

Background: Lumbar disc herniation (LDH) usually presents with lower extremity symptoms and signs, but rarely with bladder and bowel complaints. Here, we present a 61-year-old female who suffered solely from fecal incontinence (FI) attributed to a large LDH.

Case Description: The patient presented with FI, but had a normal neurological examination. Read More

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Thoracic dorsal arachnoid web with rapid onset of symptoms: A report of two cases and brief review of the literature.

Surg Neurol Int 2021 6;12:323. Epub 2021 Jul 6.

Department of Neurosurgery, University of Kentucky.

Background: Thoracic arachnoid webs are a rare entity and can be challenging to diagnose with sometimes subtle radiographic findings. Arachnoid webs can cause severe cord compression with associated syrinx and resulting myelopathy, weakness, sensory loss, and bowel/bladder dysfunction. There have been a little over 60 cases total reported in the literature with only one systematic review. Read More

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MicroRNA-490-3p and -490-5p in carcinogenesis: Separate or the same goal?

Oncol Lett 2021 Sep 22;22(3):678. Epub 2021 Jul 22.

Medical Genetics Center, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, P.R. China.

MicroRNA (miR)-490-3p and miR-490-5p, located on chromosome 7q33, are two independent mature products of miR-490 exerting distinct effects on tumor progression. miR-490-3p and miR-490-5p possess antitumor properties. miR-490-3p dysfunction has been associated with malignancies including colorectal cancer, while the abnormal function of miR-490-5p has been more considerably associated with bladder cancer (for example). Read More

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September 2021

Reliability of the Urinary Symptom Questionnaires for people with neurogenic bladder (USQNB) who void or use indwelling catheters.

Spinal Cord 2021 Aug 4. Epub 2021 Aug 4.

Department of Rehabilitation Medicine, Georgetown University Medical Center, Washington, DC, USA.

Study Design: This is a descriptive psychometrics study.

Objectives: Neurogenic lower urinary tract dysfunction (NLUTD), also called Neurogenic Bladder (NB), is a common and disruptive condition in a variety of neurologic diagnoses. Our team developed patient-centered instruments, Urinary Symptom Questionnaires for people with neurogenic bladder (USQNB), specific to people with NLUTD who manage their bladders with intermittent catheterization (IC), indwelling catheters (IDC), or who void (V). Read More

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Factors impacting bowel symptoms in a contemporary spinal cord injury cohort: results from the Neurogenic Bladder Research Group Registry.

Spinal Cord 2021 Aug 3. Epub 2021 Aug 3.

Department of Urology, Western University, London, ON, Canada.

Study Design: Cross sectional.

Objectives: To identify variables associated with severe bowel symptoms in spinal cord injured people.

Setting: National cohort. Read More

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Voiding dysfunction in children causes, management, and prognosis: A single-center retrospective study.

Saudi Med J 2021 Aug;42(8):869-877

From the Department of Pediatrics (El Desoky, Zaher, Kari); from the Paediatric Nephrology Center of Excellence (El Desoky, Kari); from the Department of Urology (Banakhar); and from the Department of Radiology (Khashoggi), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Objectives: To review voiding dysfunction caused by 3 different etiologies; dysfunction voiding syndrome (DVS), neurogenic bladder secondary to spinal dysraphisim (NB), and valve bladder syndrome (VBS).

Methods: A single-center retrospective study on children with voiding dysfunction followed up at King Abdulaziz University Hospital, Jeddah, Saudi Arabia from 2005 to 2017.

Results: One hundred and ninety-nine children (67. Read More

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Oncologic Outcomes for Robotic Vs. Open Radical Cystectomy Among Locally Advanced and Node-Positive Patients: Analysis of The National Cancer Database.

Clin Genitourin Cancer 2021 Jul 10. Epub 2021 Jul 10.

Department of Urology, George Washington University School of Medicine and Health Sciences.

Introduction: Despite concerns of atypical recurrence following robotic-assisted radical cystectomy (RARC), utilization of the modality is increasing. The presumed mechanisms of peritoneal immunomodulation and pneumoperitoneum-induced tumor cell intravasation are especially relevant for higher stage, locally advanced disease, where intrinsic metastatic potential of tumor cells may be greater. This study aims to compare the oncologic outcomes and survival after RARC compared to open radical cystectomy (ORC) among patients with stage pT3-4 or node-positive muscle-invasive bladder cancer. Read More

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Primary leiomyoma of the ureter: a case report.

J Med Case Rep 2021 Aug 3;15(1):423. Epub 2021 Aug 3.

Department of Urology, Japan Community Health Care Organization, Kani Tono Hospital, 1221-5 Dota, Kani, Gifu, 509-0206, Japan.

Background: Only 14 cases of leiomyoma with ureteral origin have been reported previously. Such primary leiomyomas often present as hydronephrosis, making the diagnosis difficult. Radical nephroureterectomy is often performed because of the possible diagnosis of a malignant tumor. Read More

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Psychological resilience of patients with bladder cancer after radical cystectomy and urinary diversion: a cross-sectional study.

Psychooncology 2021 Aug 3. Epub 2021 Aug 3.

Department of Urinary Surgery, the First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China, 110000.

Objective: The aims of this study were to investigate the current state of psychological resilience and identify its associated factors in bladder cancer (BC) patients undergoing radical cystectomy (RC).

Methods: A cross-sectional study, using convenience sampling was conducted among 248 patients recruited from urology department of a tertiary hospital in Shenyang, China. According to the resilience in illness model, participants were invited to finish a questionnaire included demographic and disease-related information, Connor-Davidson Resilience Scale, Mishel Uncertainty in Illness Scale, Medical Coping Modes Questionnaire, Social Support Rating Scale, Family APGAR Index and Herth Hope Index. Read More

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Arsenic in the geo-environment: A review of sources, geochemical processes, toxicity and removal technologies.

Environ Res 2021 Jul 31:111782. Epub 2021 Jul 31.

School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, 110067, India. Electronic address:

Impact of arsenic (As) contaminated groundwater on human health, through drinking and irrigation practices, is of grave-concern worldwide. This paper present the review of various sources, processes, health effects and treatment technologies available for the removal of As from arsenic contaminated water. Groundwater with high As concentration is detrimental to human health and incidents of As contamination in groundwater had been reported from different parts of the globe. Read More

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Down-regulation of Polo-like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signalling pathway in bladder cancer.

FEBS Open Bio 2021 Aug 3. Epub 2021 Aug 3.

Shenzhen University Health Science Center, Shenzhen, Guangdong province, China.

Polo-like kinase 4 (PLK4) has been reported to contribute to tumor growth, invasion, and metastasis. However, the role of PLK4 in human bladder cancer (BC) remains unclear. Here, we demonstrate the regulatory function of PLK4 in human BC progression. Read More

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