114,585 results match your criteria birth weight

Cue-Based Feeding as Intervention to Achieve Full Oral Feeding in Preterm Infants Primarily Managed with Bubble CPAP.

Am J Perinatol 2021 Jun 15. Epub 2021 Jun 15.

Department of Rehabilitation, the George Washington University Hospital, Washington, District of Columbia.

Objective:  Cue-based feeding aims at matching introduction of per oral (PO) feeding with physiological readiness of preterm infants to facilitate PO intake and avoid oral aversion. It was claimed that cue-based feeding may lead to delay in the initiation or achieving full PO feeding in clinical setting primarily using bubble nasal continuous positive airway pressure (CPAP). The study aimed to examine the association of cue-based feeding with time of introduction and completing oral feeding in infants primarily managed with bubble CPAP. Read More

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Bi-level Nasal Positive Airway Pressure (BiPAP) versus Nasal Continuous Positive Airway Pressure (CPAP) for Preterm Infants with Birth Weight Less Than 1500 g and Respiratory Distress Syndrome Following INSURE Treatment: A Two-center Randomized Controlled Trial.

Curr Med Sci 2021 Jun 15. Epub 2021 Jun 15.

Department of Neonatology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, China.

The present study aimed to examine the effectiveness of bi-level positive airway pressure (BiPAP) versus continuous positive airway pressure (CPAP) in preterm infants with birth weight less than 1500 g and respiratory distress syndrome (RDS) following intubation-surfactant-extubation (INSURE) treatment. A two-center randomized control trial was performed. The primary outcome was the reintubation rate of infants within 72 h of age after INSURE. Read More

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Development of an evaluation indicator system for the rational use of proton pump inhibitors in pediatric intensive care units: An application of Delphi method.

Medicine (Baltimore) 2021 Jun;100(24):e26327

Department of Pharmacy.

Abstract: Proton pump inhibitors are frequently used to prevent gastrointestinal bleeding in critically ill patients. But there is little information in the instructions about the usages for children. It is important to monitor the appropriate use of proton pump inhibitors, especially in pediatrics. Read More

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Mothers' personal growth in the first year: the role of perceived childbirth experience and support.

J Reprod Infant Psychol 2021 Jun 15:1-11. Epub 2021 Jun 15.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

: The study examined mothers' personal growth in the first year after childbirth, investigating the contribution of several aspects of the childbirth experience (assisted delivery, length of labour, pain during labour, infant's weight, gestation week, and two dimensions of the Hebrew BSS-R: perception of positive childbirth and of the quality of professional care), as well as the role of social support.: Israeli mothers (n = 408) completed a set of self-report questionnaires up to one year following the birth of their first child/ren.: Positive correlations were found between mother's growth and higher perception of the birth as positive, higher perceived care provided by the health team during labour, and higher perceived support from people close to her. Read More

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Nomogram of fetal right portal vein diameter at gestational age 30 to 35 weeks and prediction of small for gestational age at birth.

J Obstet Gynaecol Res 2021 Jun 14. Epub 2021 Jun 14.

Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.

Aim: To construct the nomogram of fetal right portal vein (RPV) diameter at 30 to 35 weeks' gestation in Thai pregnant population and the use of RPV measurement to predicting small for gestational age (SGA) fetus.

Methods: A prospective, cross-sectional study of singleton pregnancies at antenatal visit between 30 and 35 weeks of gestation in single center, Bhumibol Adulyadej Hospital (BAH) was conducted from January to August 2020. Ultrasonography of fetal biometry and RPV diameter measurement were performed as well as immediate newborn birth weight measurement. Read More

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Liver Proteome Profile of Growth Restricted and Appropriately Grown Newborn Wistar Rats Associated With Maternal Undernutrition.

Front Endocrinol (Lausanne) 2021 28;12:684220. Epub 2021 May 28.

Second Department of Obstetrics and Gynaecology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Background: Fetal growth restriction (FGR) has been associated with adverse perinatal outcomes and epigenetic modifications that impact gene expression leading to permanent changes of fetal metabolic pathways and thereby influence development of disease in childhood and adult life. In this study, we investigated the result of maternal food restriction on liver protein expression in Wistar male newborn pups.

Materials & Methods: Ten (n = 10) timed pregnant Wistar rats on their 14th day of gestation were randomly assigned to either control (n = 4) or food restricted group (n = 6). Read More

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Nasal high-frequency jet ventilation (NHFJV) as a novel means of respiratory support in extremely low birth weight infants.

J Perinatol 2021 Jun 14. Epub 2021 Jun 14.

Division of Neonatology, Department of Pediatrics, LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Objective: Describe our experience of successfully using nasal high-frequency jet ventilation (NHFJV) in extremely low birth weight infants with respiratory failure.

Study Design: A retrospective review was conducted on 16 infants with birth weights <1000 g who received NHFJV from 2015 to 2019. Successful use was defined as avoiding intubation for at least 72 hours and demonstrating tolerance after being placed on NHFJV. Read More

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The Test of Infant Motor Performance (TIMP) in very low birth weight infants and outcome at two years of age.

J Perinatol 2021 Jun 14. Epub 2021 Jun 14.

Department of Child Development, KK Women's and Children's Hospital, Singapore, Singapore.

Objective: To evaluate TIMP in preterm very low birth weight (VLBW) infants, analyze risk factors, for atypical TIMP (aTIMP) scores, and explore TIMP's predictive relationship with Bayley-III at 2 years.

Method: A prospective study of 288 VLBW infants, with TIMP assessment between 34 weeks postmenstrual age and 16 weeks age, corrected for prematurity.

Result: aTIMP scores were observed in 58/288(20%) infants, whose mean birth weight (BW) and gestational age were 1122 ± 257 g and 29. Read More

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Systematic analysis of safety profile for darunavir and its boosted agents using data mining in the FDA Adverse Event Reporting System database.

Sci Rep 2021 Jun 14;11(1):12438. Epub 2021 Jun 14.

Department of Pharmacy, Chongqing Health Center for Women and Children, Chongqing, 400021, China.

This current investigation was aimed to generate signals for adverse events (AEs) of darunavir-containing agents by data mining using the US Food and Drug Administration Adverse Event Reporting System (FAERS). All AE reports for darunavir, darunavir/ritonavir, or darunavir/cobicistat between July 2006 and December 2019 were identified. The reporting Odds Ratio (ROR), proportional reporting ratio (PRR), and Bayesian confidence propagation neural network (BCPNN) were used to detect the risk signals. Read More

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Influence of intrauterine growth status on aortic intima-media thickness and aortic diameter in near-term fetuses: a comparative cross-sectional study.

J Dev Orig Health Dis 2021 Jun 15:1-8. Epub 2021 Jun 15.

Maternal Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Aga Khan University, Pakistan.

Intrauterine undernutrition may lead to fetal vascular programming. We compared abdominal aortic intima-media thickness (aIMT) and aortic diameter (aD) between appropriate for gestational age (AGA) and growth-restricted fetuses (GRF). We recruited 136 singleton fetuses at 34-37 weeks of gestation from Fetal Medicine Unit of Aga Khan University Hospital, Karachi (January-November 2017). Read More

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Pregnancy and neonatal outcomes in women with immune mediated inflammatory diseases exposed to anti-tumor necrosis factor-α during pregnancy: A systemic review and meta-analysis.

J Autoimmun 2021 Jun 11;122:102676. Epub 2021 Jun 11.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

Background: Anti-TNFα is increasingly used as treatment for immune mediated inflammatory diseases (IMID), such as inflammatory bowel disease (IBD), rheumatoid arthritis (RA) and psoriasis (PS). However, the impact of anti-TNFα during pregnancy on mother and newborn is under debate. This requires a sound knowledge of the effects of this treatment on pregnancy and neonatal outcomes. Read More

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Effects of single and combined gestational phthalate exposure on blood pressure, blood glucose and gestational weight gain: A longitudinal analysis.

Environ Int 2021 Jun 11;155:106677. Epub 2021 Jun 11.

MOE Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), No. 81 Meishan Road, Hefei 230032, Anhui, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, No. 81 Meishan Road, Hefei 230032, Anhui, China; Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui, China; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui, China. Electronic address:

Few studies have investigated the association of gestational exposure to phthalate with metabolic risk and have reached inconsistent conclusions. Based on the Ma'anshan Birth Cohort, 3273 women were included in the present study. All participants provided up to three urine samples for 7 phthalate metabolite measurements. Read More

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Aberrant cortico-thalamic structural connectivity in premature-born adults.

Cortex 2021 May 8;141:347-362. Epub 2021 May 8.

Department of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany; TUM Neuroimaging Center, School of Medicine, Technical University of Munich, Munich, Germany; Department of Psychiatry, School of Medicine, Technical University of Munich, Munich, Germany.

Premature birth is associated with alterations in brain structure, particularly in white matter. Among white matter, alterations in cortico-thalamic connections are present in premature-born infants, and they have been suggested both to last until adulthood and to contribute to impaired cognitive functions. To test these hypotheses, 70 very premature-born adults and 67 full-term controls underwent cognitive testing and diffusion-weighted imaging. Read More

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The associations of birth outcome differences in twins with prenatal exposure to bisphenol A and its alternatives.

Environ Res 2021 Jun 11:111459. Epub 2021 Jun 11.

Department of Occupational and Environmental Health, School of Basic Medicine and Public Health, Jinan University, Guangzhou, Guangdong, PR China. Electronic address:

Background: Bisphenol A (BPA) and its alternatives, including BPF and BPS, exhibit endocrine disruption activities. However, the effects of bisphenols on fetal growth in twins remain unclear.

Objective: To explore the associations of prenatal BPA, BPF, and BPS exposure with birth outcome differences in twins. Read More

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Evaluation of vitamin D protocol in the neonatal intensive care unit at Rush University Medical Center.

JPEN J Parenter Enteral Nutr 2021 Jun 14. Epub 2021 Jun 14.

Division of Neonatology, Department of Pediatrics, Rush University Medical Center, Chicago, Illinois, USA.

Background: In 2017, the neonatal intensive care unit (NICU) at Rush University Medical Center (RUMC) implemented a protocol to provide individualized vitamin D supplementation dosing for very low-birth-weight (VLBW) and very preterm infants. This study evaluated the association of demographic and socioeconomic factors, vitamin D dose, and health indicators, including bone mineral status, measured by alkaline phosphatase and phosphorus levels; linear growth velocity; and occurrence of fractures.

Method: This retrospective cross-sectional study included 227 VLBW or very preterm infants (34 VLBW, 12 very preterm, and 181 VLBW and very preterm) born in and discharged from the RUMC NICU between February 1, 2017, and October 31, 2019. Read More

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Longitudinal assessment of cardiac function in extremely low birth weight children at 7 and 11 years of age: implications for adult medicine.

Kardiol Pol 2021 ;79(5):539-545

Department of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.

Background: The long-term impact of extreme prematurity on cardiac structure and function has not been fully evaluated.

Aims: The aim of the study was to assess cardiac condition at 11 years of age in a local cohort of extremely low birth weight (ELBW) children born between 2002 and 2004 and to compare it to a previous study in the same group at 7 years of age.

Methods: Sixty-four children with ELBW (median birth weight of 890 g) and 36 children born at full term underwent echocardiography and physical examination. Read More

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January 2021

Impact of a prenatal education intervention in pregnant women to prevent overweight in infants.

Gac Med Mex 2021 ;157(1):3-9

Faculty of Nursing, Universidad Autónoma de Nuevo León, Nuevo León. Mexico.

Introduction: During the first 1000 days of life is the basis for a child's future health established.

Objective: To evaluate the impact of a prenatal educational intervention in pregnant women on the nutritional status of the child from birth to 4 months of age.

Methods: Quasi-experimental intervention design in women with at least 12 weeks of gestation, who were randomly assigned to an intervention group (IG) to participate in five group and three individual sessions on feeding practices and maternal perception of the child's weight and signals of hunger-satiety; the control group (CG) received routine care that included at least three prenatal consultations. Read More

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January 2021

Identification of maternal continuous glucose monitoring metrics related to newborn birth weight in pregnant women with gestational diabetes.

Endocrine 2021 Jun 14. Epub 2021 Jun 14.

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Purpose: To identify the specific glucose metrics derived from maternal continuous glucose monitoring (CGM) data, which were associated with a higher percentile of offspring birth weight.

Methods: In this cohort study, we recruited singleton pregnant women with GDM who underwent CGM for 5-14 days at a mean of 28.8 gestational weeks between Jan 2017 and Nov 2018. Read More

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Association Between Childhood Consumption of Ultraprocessed Food and Adiposity Trajectories in the Avon Longitudinal Study of Parents and Children Birth Cohort.

JAMA Pediatr 2021 Jun 14:e211573. Epub 2021 Jun 14.

Public Health Policy Evaluation Unit, Imperial College London, London, United Kingdom.

Importance: Reports of associations between higher consumption of ultraprocessed foods (UPF) and elevated risks of obesity, noncommunicable diseases, and mortality in adults are increasing. However, associations of UPF consumption with long-term adiposity trajectories have never been investigated in children.

Objective: To assess longitudinal associations between UPF consumption and adiposity trajectories from childhood to early adulthood. Read More

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Metabolic Hormone Profiles in Breast Milk From Mothers of Moderate-Late Preterm Infants Are Associated With Growth From Birth to 4 Months in a Sex-Specific Manner.

Front Nutr 2021 28;8:641227. Epub 2021 May 28.

The Liggins Institute, University of Auckland, Auckland, New Zealand.

Differing environmental conditions experienced by mother-infant dyads may influence composition of the milk received by the infant. As a consequence, diverse milk compositional profiles may contribute to different postnatal outcomes, especially in infants facing adverse perinatal environments. We investigated whether variability in milk concentrations of key metabolic hormones is associated with different growth outcomes in infants born preterm, a perinatal complication known to impact on infant growth. Read More

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Reference Charts for Neonatal Cranial Volume Based on 3D Laser Scanning to Monitor Head Growth.

Front Pediatr 2021 28;9:654112. Epub 2021 May 28.

Division of Neonatology and Pediatric Intensive Care Medicine, Department of Pediatrics, Medizinische Fakultät der Technischen Universität, Dresden, Germany.

Postnatal brain growth is an important predictor of neurodevelopmental outcome in preterm infants. A new reliable proxy for brain volume is cranial volume, which can be measured routinely by 3-D laser scanning. The aim of this study was to develop reference charts for normal cranial volume in newborn infants at different gestational ages starting from late preterm for both sexes. Read More

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Effect of Early Supplemental Formula Intervention on Body Weight and Hyperbilirubinemia in Neonates During 72 h After Birth.

Front Pediatr 2021 26;9:625536. Epub 2021 May 26.

Department of Pediatric Emergency Medicine, China Medical University Children's Hospital, Taichung, Taiwan.

The full breastfeeding may lead to insufficient milk intake of newborns and increase the rate of body weight loss (BWL). Severe BWL was generally believed as a cause of significant hyperbilirubinemia in newborn babies. The study aimed to investigate the effect if early supplemental feeding in newborns with birth weight loss at the first 3 days after birth could decrease the rate of hyperbilirubinemia 72 h of birth. Read More

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Heat Shock Protein-70 Levels Are Associated With a State of Oxidative Damage in the Development of Bronchopulmonary Dysplasia.

Front Pediatr 2021 26;9:616452. Epub 2021 May 26.

Department of Pediatrics, Changhua Christian Children's Hospital, Changhua, Taiwan.

Heat shock protein-70 (Hsp-70) exhibits cytoprotective effects against oxidative stress-induced airway injury. This study aimed to examine Hsp-70 and 8-hydroxy-2'-deoxyguanosine (8-OHdG) from tracheal aspirates (TA) in very low-birth weight (VLBW) preterm infants to predict the development of bronchopulmonary dysplasia (BPD). This birth cohort study enrolled 109 VLBW preterm infants, including 32 infants who developed BPD. Read More

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Maternal methionine supplementation in mice affects long-term body weight and locomotor activity of adult female offspring.

Br J Nutr 2021 Jun 14:1-27. Epub 2021 Jun 14.

Department of Psychobiology, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, São Paulo, SP, Brazil.

Methionine is a precursor of s-adenosylmethionine (SAM), the main donor of methyl radicals for methylation of DNA and other compounds. Previous studies have shown that reduced availability of methyl radicals during pregnancy/lactation decreased offspring perigonadal white adipose tissue (PWAT) and body weight. Therefore, we aimed to evaluate the effects of methionine supplementation during early development, a time of great ontogenic plasticity, by assessing the biometric, biochemical, and behavioral parameters of the offspring of adult Swiss female mice supplemented with 1% methionine in water one month before pregnancy, and during pregnancy or pregnancy/lactation. Read More

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Perinatal hypoxia leads to primordial follicle activation and premature depletion of ovarian reserve.

J Matern Fetal Neonatal Med 2021 Jun 13:1-5. Epub 2021 Jun 13.

IVF Unit, Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.

Background: The human ovary contains 6-million follicles during the 20th week of embryonic development and 1 million at birth. Girls born at small for gestational age weight demonstrate higher FSH levels during infancy, an earlier onset of puberty, and menarche. In light of these observations, we hypothesized that exposure to hypoxia at the early neonatal period might impact the primordial follicular pool and lead to premature depletion of ovarian reserve. Read More

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Red blood cell transfusion thresholds in extremely low birth weight infants II.

Erin Grace Amy Keir

Acta Paediatr 2021 Jun 13. Epub 2021 Jun 13.

Department of Neonatal Medicine, Women's and Children's Hospital, North Adelaide, SA, Australia.

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Impact of early postnatal exposure of red blood cell transfusions on the severity of retinopathy of prematurity.

J Neonatal Perinatal Med 2021 Jun 5. Epub 2021 Jun 5.

Department of Pediatrics, University of Maryland School Of Medicine, USA.

Background: Postnatal exposure to red blood cell transfusion (RBCT) in premature infants is an important risk factor for Retinopathy of Prematurity (ROP) progression. We hypothesized that higher number and earlier timing of RBCT are associated with worse ROP severity and result in laser treatment at an earlier postmenstrual age (PMA) in very low birth weight (≤1500 g, VLBW) infants.

Methods: A retrospective medical record review of 631 VLBW infants over a 5-year period was performed. Read More

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Care practices and outcomes of extremely preterm neonates born at 22-24 weeks -A single centre experience.

J Neonatal Perinatal Med 2021 Jun 5. Epub 2021 Jun 5.

Newborn Services, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Background: Wide variation in the care practices and survival rates of neonates born at peri-viable gestational ages of 22 +0 -24 +6 weeks exists. This study elucidates the postnatal risk factors for morbidity/mortality, contrasts the care practices and short-term outcomes of this vulnerable group of preterm neonates from a single center with others.

Methods: Retrospective study of neonates born at 22 +0 -24 +6 weeks in a level 3 neonatal intensive care unit in UK, over a period of 4 years (2016-2019). Read More

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Predictors of mortality in premature babies with respiratory distress syndrome treated by early rescue surfactant therapy.

J Neonatal Perinatal Med 2021 Jun 7. Epub 2021 Jun 7.

Department of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Objective: To determine the predictors of mortality following early rescue surfactant therapy in preterm babies with respiratory distress syndrome.

Study Design: Prospective cohort study enrolling babies between 28 weeks to 34 weeks with respiratory distress syndrome requiring early rescue surfactant therapy. For statistical analysis babies were further divided into two subgroups: survivors and non-survivors. Read More

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Intracranial hemorrhage secondary to vitamin K deficiency in X-linked myotubular myopathy.

Neuromuscul Disord 2021 May 11. Epub 2021 May 11.

Division of Critical Care Medicine, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, United States; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States; Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States. Electronic address:

X-linked myotubular myopathy (XLMTM) is a rare congenital myopathy characterized by profound hypotonia and poor respiratory effort at birth. The condition is associated with multiple morbidities including chronic respiratory insufficiency, feeding tube dependence, and rarely, vitamin K deficiency leading to bleeding and coagulopathy. We report a case of a 6-month-old boy with X-linked myotubular myopathy who experienced a fatal intracranial hemorrhage due to vitamin K deficiency without prior clinical evidence of cholestasis or micronutrient deficiency. Read More

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