J Pediatr 2021 Jun 15. Epub 2021 Jun 15.
INSERM U1245, Genetics and Pathophysiology of Neurodevelopmental Disorders Team, Institute of Research and Innovation in Biomedicine, Faculty of Medicine, Normandy, University, France; Department of Neonatal Pediatrics and Intensive Care - Neuropediatrics, CHU Rouen, Rouen, France. Electronic address:
Objectives: To describe the prevalence of cerebral palsy (CP) at age 2 years in infants born before 33 weeks of gestation and to analyze the fetal neuroprotective effect of the antenatal administration of magnesium sulfate treatment on CP.
Study Design: Preterm infants born before 33 weeks of gestation and discharged from the Rouen University Hospital Neonatal Intensive Care Unit (NICU) between 2007 and 2015 were included. At age 2 years, pediatricians of the perinatal network of the Eure and the Seine-Maritime counties administered standardized questionnaires analyzing motor, cognitive, and behavioral items, derived from the Denver and Amiel-Tison scales. Read More