25,738 results match your criteria birth odds


Time interval from late preterm antenatal corticosteroid administration to delivery and the impact on neonatal outcomes.

Am J Obstet Gynecol MFM 2021 Jun 18:100426. Epub 2021 Jun 18.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Lenox Hill Hospital -Zucker School of Medicine at Hofstra/Northwell, New York, NY.

Background: While administration of antenatal corticosteroids (ACS) has been shown to decrease neonatal respiratory morbidity when given to women at risk for late preterm birth, the time interval from ACS to delivery associated with the greatest neonatal benefit remains unknown.

Objective: To evaluate whether time interval from administration of late preterm ACS to delivery is associated with a change in the likelihood of transient tachypnea of the newborn (TTN), respiratory distress syndrome (RDS), and hypoglycemia.

Study Design: Retrospective cohort of all singleton neonates who were exposed to one or two doses of ACS in the late preterm period (34 0/7-36 6/7 weeks) within a large health system between November 2017 and March 2020. Read More

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Impact of YTHDF1 gene polymorphisms on Wilms tumor susceptibility: A five-center case-control study.

J Clin Lab Anal 2021 Jun 21:e23875. Epub 2021 Jun 21.

Department of General Surgery, Xi'an Children's Hospital, Xi'an Jiaotong University Affiliated Children's Hospital, Xi'an, China.

Background: Wilms tumor is the most frequent renal malignancy in children. YTHDF1 is associated with the development of several kinds of cancers, yet whether common variants of the YTHDF1 gene influence Wilms tumor risk is unknown. We present, here, a hospital-based case-control study specifically designed to investigate the role of YTHDF1 genetic variants on Wilms tumor. Read More

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Risk Factors of Stillbirth Among Women Who Gave Birth in Amhara Region Referral Hospitals, Ethiopia, in 2019: A Case-Control Study.

Int J Womens Health 2021 11;13:557-567. Epub 2021 Jun 11.

Department of Women's and Family Health, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Worldwide, 2.6 million stillbirths occur annually and more than three-quarters of them are recorded in South Asia and Sub-Saharan Africa. Thus, the aim of this study was to identify risk factors of stillbirth among women who gave birth in Amhara region referral hospitals found in northwest and northcentral, Ethiopia in 2019. Read More

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Obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran: a retrospective, case-control study.

Middle East Fertil Soc J 2021 14;26(1):17. Epub 2021 Jun 14.

Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

Background: The purpose of the present study was to evaluate obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran.

Results: A case-control study was conducted on 55 COVID-19 as the case and 55 matched control pregnant women in Hormozgan, Iran. Patients were considered to be cases if they had a positive COVID-19 test plus a positive chest X-ray result. Read More

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The evolving landscape of donor egg treatment: success, women's choice, and anonymity.

J Assist Reprod Genet 2021 Jun 20. Epub 2021 Jun 20.

Zucker School of Medicine at Hofstra/Northwell, Northwell Fertility, New York, NY, 10065, USA.

Purpose: To analyze donor oocyte (DE) data across 6 years for oocyte usage efficiency, trends, and whether changes impacted outcomes.

Methods: From 2014 to 2019, 323 DE embryo transfers were completed in 200 recipients using oocytes derived of 163 donors. We assessed data for oocytes being freshly retrieved (FRESH-EGG) vs. Read More

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Juvenile-Onset Recurrent Respiratory Papillomatosis in the United States, Epidemiology and HPV Types-2015-2020.

J Pediatric Infect Dis Soc 2021 Jun 19. Epub 2021 Jun 19.

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Background: Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a rare disease characterized by the growth of papillomas in the respiratory tract. In the United States, JORRP is not a nationally notifiable condition and current data are limited.

Methods: Children with JORRP aged <18 years were enrolled from 26 pediatric otolaryngology centers in 23 US states from January 2015 through August 2020. Read More

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Associations between maternal and environmental exposures on atopic disease in the offspring of mothers with asthma.

Immun Inflamm Dis 2021 Jun 19. Epub 2021 Jun 19.

Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Background And Objective: Available data on the impact of perinatal and environmental factors on atopic diseases in the offspring are sparse and conflicting. We, therefore, investigated the impact of these factors on the risk of atopic diseases in the offspring of women with asthma.

Methods: Pregnant women referred to give birth at Copenhagen University Hospital-Hvidovre, Denmark, have since 2007 been invited to participate in the Management of Asthma during Pregnancy program. Read More

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Risk of Feeding Problems Among Infants With Neonatal Abstinence Syndrome: A Retrospective Cohort Study.

Adv Neonatal Care 2021 Jun 18. Epub 2021 Jun 18.

Department of Family and Preventive Medicine, University of Utah, Salt Lake City (Ms Mensah and Dr Qeadan); and Department of Family Medicine and Public Health Sciences, Wayne State University, Detroit, Michigan (Dr Madden).

Background: The rate of infants born with neonatal abstinence syndrome (NAS) increased by more than 500% between 2004 and 2016. Although feeding problems among infants diagnosed with NAS have been documented, the risk of feeding problems among infants diagnosed with NAS has not been estimated.

Purpose: This study evaluates the extent to which feeding problems among infants diagnosed with NAS differ from thise in infants without an NAS diagnosis. Read More

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Cerebral Palsy in Very Preterm Infants: A Nine-Year Prospective Study in a French Population-Based Tertiary Center.

J Pediatr 2021 Jun 15. Epub 2021 Jun 15.

INSERM U1245, Genetics and Pathophysiology of Neurodevelopmental Disorders Team, Institute of Research and Innovation in Biomedicine, Faculty of Medicine, Normandy, University, France; Department of Neonatal Pediatrics and Intensive Care - Neuropediatrics, CHU Rouen, Rouen, France. Electronic address:

Objectives: To describe the prevalence of cerebral palsy (CP) at age 2 years in infants born before 33 weeks of gestation and to analyze the fetal neuroprotective effect of the antenatal administration of magnesium sulfate treatment on CP.

Study Design: Preterm infants born before 33 weeks of gestation and discharged from the Rouen University Hospital Neonatal Intensive Care Unit (NICU) between 2007 and 2015 were included. At age 2 years, pediatricians of the perinatal network of the Eure and the Seine-Maritime counties administered standardized questionnaires analyzing motor, cognitive, and behavioral items, derived from the Denver and Amiel-Tison scales. Read More

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The Influence of a Sister's Breastfeeding Experience on a Mother's Breastfeeding Behavior: Is There an Intragenerational Effect?

Breastfeed Med 2021 Jun 18. Epub 2021 Jun 18.

Department of Pediatrics, Brody School of Medicine at East Carolina University, Greenville, North Carolina, USA.

Intergenerational transmission of breastfeeding attitudes and behaviors from mother to daughter are well known, but there is limited research on intragenerational transmission of breastfeeding attitudes or behaviors within families. This study aimed to understand how initiation and duration of breastfeeding are influenced by past breastfeeding experiences of sisters among women in a longitudinal population-based cohort. Data were obtained on women enrolled in the 1979 National Longitudinal Survey of Youth (NLSY) who had at least one child enrolled in a substudy of cohort members' children. Read More

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Effects of Maternal Exercise During Pregnancy on Perinatal Growth and Childhood Obesity Outcomes: A Meta-analysis and Meta-regression.

Sports Med 2021 Jun 18. Epub 2021 Jun 18.

Center for Reproductive Biology, School of Molecular Biosciences, Washington State University, Pullman, WA, 99164, USA.

Background: Perinatal growth abnormalities program susceptibility to childhood obesity, which is further exaggerated by maternal overweight and obesity (MO) during pregnancy. Exercise is highly accessible, but reports about the benefits of maternal exercise on fetal growth and childhood obesity outcomes are inconsistent, reducing the incentives for pregnant women to participate in exercise to improve children's perinatal growth.

Objective: This systematic review and meta-analysis aims to establish evidence-based efficacy of exercise in mothers with normal weight (MNW) and MO during pregnancy in reducing the risks of perinatal growth abnormalities and childhood obesity. Read More

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Low CLOCK and CRY2 in 2nd trimester human maternal blood and risk of preterm birth: A nested case-control study.

Biol Reprod 2021 Jun 18. Epub 2021 Jun 18.

Department of Animal Science, The Reproductive and Developmental Sciences Program, College of Agriculture and Natural Resources, Michigan State University, USA.

Previous studies have observed an association between maternal circadian rhythm disruption and preterm birth (PTB). However, the underlying molecular mechanisms and the potential of circadian clock genes to serve as predictors of PTB remain unexplored. We examined the association of 10 core circadian transcripts in maternal blood with spontaneous PTB (sPTB) vs term births using a nested case-control study design. Read More

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Maternal exposure to smoking and infant's wheeze and asthma: Japan Environment and Children's Study.

Allergol Int 2021 Jun 14. Epub 2021 Jun 14.

Department of Public Health, Faculty of Medicine, University of Toyama, Toyama, Japan; Toyama Regional Center for Japan Environment and Children's Study (JECS), University of Toyama, Toyama, Japan.

Background: Evidence regarding independent effects of maternal smoking in different time frames of pregnancy and maternal exposure to secondhand smoke on the development of wheeze/asthma in her offspring is limited. We aimed to investigate the effect of maternal exposure to tobacco smoke on wheeze/asthma development at 1 year of age in her offspring using data from the nationwide birth cohort study in Japan.

Methods: Pregnant women who lived in the 15 designated regional centers throughout Japan were recruited. Read More

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Residential exposure to carbamate, organophosphate, and pyrethroid insecticides in house dust and risk of childhood acute lymphoblastic leukemia.

Environ Res 2021 Jun 14:111501. Epub 2021 Jun 14.

Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Department of Health and Human Services, 9609 Medical Center Dr., Rockville, MD, 20850, USA.

Background: Self-reported residential use of pesticides has consistently been associated with increased risk of childhood leukemia. However, these studies were limited in their ability to identify specific insecticide active ingredients that were associated with risk.

Objective: We used household carpet dust measurements of 20 insecticides (two carbamate, 10 organophosphate, two organochlorine, and six pyrethroid) as indicators of exposure and evaluated associations with the risk of childhood acute lymphoblastic leukemia (ALL). Read More

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Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study.

BJOG 2021 Jun 17. Epub 2021 Jun 17.

Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.

Objective: To assess the association between vaginal microbiome (VMB) composition and recurrent early spontaneous preterm birth (sPTB)/preterm prelabour rupture of membranes (PPROM).

Design: Nested case-control study.

Setting: UK tertiary referral hospital. Read More

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Factors associated with births protected against neonatal tetanus in Africa: Evidences from Demographic and health surveys of five African countries.

PLoS One 2021 17;16(6):e0253126. Epub 2021 Jun 17.

Department of Physiology, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Introduction: Maternal and neonatal tetanus remains a global public health problem affecting mainly the poorest and most marginalized subpopulations. In spite of the problem, studies conducted on the associated factors of births protected against neonatal tetanus are scarce in Africa. Therefore, this study aimed to identify both individual and community-level factors associated with births protected against neonatal tetanus in the region. Read More

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Association between early-term birth and delayed neurodevelopment at the age of 2 years: results from a cohort study in China.

Eur J Pediatr 2021 Jun 17. Epub 2021 Jun 17.

Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, 100 Hong Kong Road, Wuhan, 430015, Hubei, China.

A growing body of evidence indicates that early-term births (37-38 weeks of gestational age) have an increased risk of short-term and long-term complications. Here, we sought to explore the association between early-term births and the risk of delayed neurodevelopment at age 2 years. Pregnant women and their live singleton birth were recruited from a single tertiary hospital between October 2013 and February 2017. Read More

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Pregnancy outcomes among evacuees of the Sinabung volcano, 2010-2018 (North Sumatra, Indonesia): A matched cohort study.

Am J Hum Biol 2021 Jun 17:e23628. Epub 2021 Jun 17.

Department of Anthropology, University of North Sumatra, Medan, Indonesia.

Objectives: Exposure to natural disasters during pregnancy is associated with adverse birth outcomes and increased probability of female births. Nonetheless, relatively little work has been done on evacuations of women living in close vicinity to volcanic eruptions. We conducted a retrospective cohort study among women from villages near the Sinabung volcano in North Sumatra, Indonesia, which has been active since 2010. Read More

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Maternal risk factors and pregnancy complications associated with low birth weight neonates in preterm birth.

J Obstet Gynaecol Res 2021 Jun 16. Epub 2021 Jun 16.

Medical Information Office, Maternal and Children Health Care Hospital (Huzhong Hospital) of Huadu, Guangzhou, China.

Aim: To explore the association between common pregnancy complications and low birth weight (LBW) neonates in preterm birth.

Methods: The study included 1764 pregnant women who experienced a single birth prematurely at a city hospital in Guangzhou, China between January 1, 2017 and December 31, 2019. A total of 874 normal birth weight neonates and 890 LBW neonates were included. Read More

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Investigating the efficacy and safety of metronidazole during pregnancy; A systematic review and meta-analysis.

Eur J Obstet Gynecol Reprod Biol X 2021 Jul 14;11:100128. Epub 2021 May 14.

Agence Nationale de Sécurité du Médicament et des Produits de santé (ANSM), France.

Objective: We aimed to review and analyze studies focusing on the efficacy of metronidazole in reducing the risk of preterm birth and the safety of metronidazole taking into account the different doses, duration of treatment and routes of administration.

Study Designs: Embase, Cochrane Library and PubMed were searched up to 29 July 2019 to identify studies assessing metronidazole exposure during pregnancy. Additional studies were identified from reference lists of retrieved papers. Read More

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Normal Gestational Weight Gain Protects From Large-for-Gestational-Age Birth Among Women With Obesity and Gestational Diabetes.

Front Public Health 2021 31;9:550860. Epub 2021 May 31.

PEDEGO Research Unit, Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland.

Pre-pregnancy obesity, excess gestational weight gain (GWG), and gestational diabetes (GDM) increase fetal growth. Our aim was to assess whether normal GWG is associated with lower risk for a large-for-gestational-age (LGA; over the 90th percentile of birth weight for sex and gestational age) infant and lower birth weight standard deviation (SD) score in the presence of GDM and maternal obesity. This multicenter case-control study is part of the Finnish Gestational Diabetes (FinnGeDi) Study and includes singleton pregnancies of 1,055 women with GDM and 1,032 non-diabetic controls. Read More

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Methamphetamine use and psychotic symptoms: findings from a New Zealand longitudinal birth cohort.

Psychol Med 2021 Jun 17:1-8. Epub 2021 Jun 17.

National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.

Background: This study examined the association between methamphetamine use and psychotic symptoms in a New Zealand general population birth cohort (n = 1265 at birth).

Methods: At age 18, 21, 25, 30, and 35, participants reported on their methamphetamine use and psychotic symptoms in the period since the previous interview. Generalized estimating equations modelled the association between methamphetamine use and psychotic symptoms (percentage reporting any symptom, and number of symptoms per participant). Read More

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Prenatal household air pollutant exposure is associated with reduced size and gestational age at birth among a cohort of Ghanaian infants.

Environ Int 2021 Jun 13;155:106659. Epub 2021 Jun 13.

Kintampo Health Research Centre, Kintampo, Ghana.

Background: Low birth weight and prematurity are important risk factors for death and disability, and may be affected by prenatal exposure to household air pollution (HAP).

Methods: We investigate associations between maternal exposure to carbon monoxide (CO) during pregnancy and birth outcomes (birth weight, birth length, head circumference, gestational age, low birth weight, small for gestational age, and preterm birth) among 1288 live-born infants in the Ghana Randomized Air Pollution and Health Study (GRAPHS). We evaluate whether evidence of malaria during pregnancy, as determined by placental histopathology, modifies these associations. Read More

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Influence of social determinants of health on skin to skin contact between mother and newborn.

Rev Bras Enferm 2021 11;74(suppl 4):e20200138. Epub 2021 Jun 11.

Universidade Federal do Piauí. Teresina, Piauí, Brazil.

Objective: to analyze the association of skin-to-skin contact and social determinants of health.

Methods: this is a cross-sectional study with 187 medical records of newborns from a reference rooming in in northeastern Brazil. An instrument with maternal and neonatal data was used. Read More

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Health care in the first year of life of a prospective cohort of late-preterm and full-term infants, in Botucatu, state of São Paulo, Brazil, 2015-2017.

Epidemiol Serv Saude 2021 ;30(2):e2020619

Universidade Estadual Paulista 'Júlio de Mesquita Filho', Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.

Objective: To assess association between late-preterm birth and use of referral health services in the first year of life.

Methods: This was a prospective cohort study, with data collected from infants at 1, 3, 6, 9 and 12 months old. Maternal and birth characteristics were compared between full-term and late preterm infants. Read More

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January 2021

Systematic review and meta-analysis of vitamin D deficiency in different pregnancy on preterm birth: Deficiency in middle pregnancy might be at risk.

Medicine (Baltimore) 2021 Jun;100(24):e26303

Gansu Provincial Maternity and Child-Care Hospital.

Background: Current studies suggest that vitamin D deficiency during pregnancy can produce a certain effect for preterm birth (PTB), but there is no research showing whether vitamin D deficiency has a consistent effect in different pregnancies; thus, we conducted a systematic review and meta-analysis of 24 observational studies, grouping them according to the gestational age at the time of serum sampling, to investigate whether vitamin D deficiency in different periods of gestation has different effects on PTB and to provide an evidence-based basis for pregnant women to measure and supplement vitamin D.

Methods: The databases PubMed-Medline, EMBASE, the Cochrane Library, Web of Science, EBSCO, CBM, and CNKI were searched until February 2020. Two researchers independently assessed the eligibility and quality of studies, and STATA 12. Read More

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Length of estradiol exposure >100 pg/ml in the follicular phase affects pregnancy outcomes in natural frozen embryo transfer cycles.

Hum Reprod 2021 Jun;36(7):1932-1940

The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, NY, USA.

Study Question: Do the length of follicular phase estradiol exposure and the total length of the follicular phase affect pregnancy and live birth outcomes in natural frozen embryo transfer (FET) cycles?

Summary Answer: An estradiol level >100 pg/ml for ≤4 days including the LH surge day is associated with worse pregnancy and live birth outcomes; however, the total length of the follicular phase is not associated with pregnancy and live birth outcomes.

What Is Known Already: An estradiol level that increases above 100 pg/ml and continues to increase is indicative of the selection and development of a dominant follicle. In programmed FET cycles, a limited duration of follicular phase estradiol of <9 days results in worse pregnancy rates, but a prolonged exposure to follicular phase estradiol for up to 4 weeks does not affect pregnancy outcomes. Read More

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Systematic analysis of safety profile for darunavir and its boosted agents using data mining in the FDA Adverse Event Reporting System database.

Sci Rep 2021 Jun 14;11(1):12438. Epub 2021 Jun 14.

Department of Pharmacy, Chongqing Health Center for Women and Children, Chongqing, 400021, China.

This current investigation was aimed to generate signals for adverse events (AEs) of darunavir-containing agents by data mining using the US Food and Drug Administration Adverse Event Reporting System (FAERS). All AE reports for darunavir, darunavir/ritonavir, or darunavir/cobicistat between July 2006 and December 2019 were identified. The reporting Odds Ratio (ROR), proportional reporting ratio (PRR), and Bayesian confidence propagation neural network (BCPNN) were used to detect the risk signals. Read More

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Post-vaccination HPV seroprevalence among female sexual health clinic attenders in England.

Vaccine 2021 Jun 11. Epub 2021 Jun 11.

Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Service, Public Health England, London, UK.

Background: The National HPV Immunisation Programme was introduced in England in September 2008 using the HPV16/18 bivalent vaccine. We conducted serological surveillance to explore vaccination coverage levels. We also conducted a case-control study to investigate a hypothesised cross-protective effect of the HPV16/18 vaccine against genital warts. Read More

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