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Int J Gynaecol Obstet 2022 May 22. Epub 2022 May 22.

Institute of Integral Medicine Prof. Fernando Figueira (IMIP), Integrated Study Group on Nutrition and Health, Recife, PE, Brazil.

Objective: To determine the prevalence of anemia among pregnant women and the associated factors and perinatal outcomes according to two different diagnostic criteria: the World Health Organization (WHO) and the Center for Disease Control and Prevention (CDC) criteria.

Methods: Cohort study, operationalized through a database. The sample was comprised of 781 pregnant women who had laboratory data regarding hemoglobin levels during the second trimester of pregnancy. Read More

J Assoc Physicians India 2022 May;70(5):11-12

Professor, Bangur Institute of Neurosciences IPGMER & SSKM Hospital Annex-1, , Kolkata, West Bengal; * Corresponding Author.

Introduction: Neurological disorders in pregnancy may be observed in patients with a pre-existing neurological disorder; patients developing a primary neurological disorder during the course of pregnancy or puerperium; and in patients with primary medical disorders presenting with neurological manifestations.

Objectives: The objectives of the study were to find out the magnitude of neurological disorders in pregnancy in a tertiary care hospital along with assessment of proportion of women with particular disorders among total number of neurological disorders during the course of pregnancy or puerperium (6 weeks after child birth) and also to elicit the effect of neurological disorders on pregnancy outcome, if any.

Methods: A prospective observational longitudinal study was carried out in a tertiary care centre of Eastern India from July 2018 to June 2020 including all pregnant women attending the department of Obstetrics and Gynaecology. Read More

BMC Public Health 2022 May 21;22(1):1024. Epub 2022 May 21.

Nurse-Family Partnership, National Service Office, 1900 Grant Street, Suite 400, Denver, CO, 80203, USA.

Background: The US is scaling up evidence-based home visiting to promote health equity in expectant families and families with young children. Persistently small average effects for full models argue for a new research paradigm to understand what interventions within models work best, for which families, in which contexts, why, and how. Historically, the complexity and proprietary nature of most evidence-based models have been barriers to such research. Read More

Int Breastfeed J 2022 May 21;17(1):40. Epub 2022 May 21.

Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong SAR, China.

Background: In the past decade, various breastfeeding policies were implemented in Hong Kong, including changes in perinatal guidelines in public hospitals, adoption of the Baby-Friendly Hospital Initiative (BFHI), provision of guidelines for the marketing of formula milk, penalisation of discrimination towards breastfeeding, and extension of the statutory maternity leave. Meanwhile, the COVID-19 pandemic brought new challenges and opportunities to breastfeeding practices. Infection control measures in public hospitals included the cancellation of antenatal classes, hospital tours, and postnatal classes; suspension of perinatal visiting periods; and compulsory separation of COVID-19 positive mothers from newborns. Read More

BMC Pregnancy Childbirth 2022 May 21;22(1):428. Epub 2022 May 21.

School of Nursing and Midwifery, Western Sydney University, Locked Bag 1797, Penrith, NSW, 2751, Australia.

Background: There is a tiered healthcare system in Australia to support maternal and child health, including, non-psychiatric day stay and residential parenting services (RPS) such as Tresillian and Karitane (in New South Wales [NSW]). RPS are unique to Australia, and currently there is limited information regarding the healthcare trajectory of women accessing RPS and if they are more likely to have admissions to other health facilities within the first-year post-birth. This study aimed to examine differences in hospital co-admissions for women and babies admitted to RPS in NSW in the year following birth compared to non-RPS admitted women. Read More

BMC Cardiovasc Disord 2022 May 21;22(1):235. Epub 2022 May 21.

Department of Radiology, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, China.

Background: To elucidate the value of texture analysis (TA) in detecting and differentiating myocardial tissue alterations on T2-weighted CMR (cardiovascular magnetic resonance imaging) in patients with cardiac amyloidosis (CA) and hypertrophic cardiomyopathy (HCM).

Methods: In this retrospective study, 100 CA (58.5 ± 10. Read More

Pediatr Res 2022 May 21. Epub 2022 May 21.

Division of Neonatology, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

This narrative review focuses on the clinical use and relevance of cerebral oxygenation measured by NIRS during fetal to neonatal transition. Cerebral NIRS(cNIRS) offers the possibility of non-invasive, continuous, and objective brain monitoring in addition to the recommended routine monitoring. During the last decade, with growing interest in early and sensitive brain monitoring, many research groups worldwide have been working with cNIRS and verified the feasibility of cNIRS monitoring immediately after birth. Read More

Sci Rep 2022 May 21;12(1):8596. Epub 2022 May 21.

Department of Pediatric Gastroenterology, Dana Dwek Children's Hospital, Tel Aviv Medical Center, Tel Aviv, Israel.

Knowledge and understanding of risk mechanisms associated with pediatric feeding disorder (PFD) remain limited. We aimed to investigate factors associated with PFD and their relation to specific PFD types according to the recent consensus WHO-based definition. We retrospectively reviewed the medical records of children with PFD and retrieved their demographic and clinical characteristics. Read More

J Allergy Clin Immunol Pract 2022 Apr 30. Epub 2022 Apr 30.

Population Health, Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia. Electronic address:

Background: The association between mode of delivery and the risk of food allergy remains unclear due to the absence of studies with both challenge-proven food allergy outcomes and detailed information on the type of caesarean delivery.

Objective: We assessed whether emergency or elective caesarean, or caesarean delivery in the presence or absence of labor initiation, is associated with the risk of food allergy.

Methods: The HealthNuts study recruited 5276 12-month-old infants who underwent skin prick testing and oral food challenge to ascertain food allergy status, and linked the child's study data to additional birth data from the Victorian Perinatal Data Collection. Read More

Neuromuscul Disord 2022 Apr 30. Epub 2022 Apr 30.

Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, MS S106-3, 4770 Buford Hwy, Chamblee, GA 30341-3717, United States of America.

Population-based estimates of survival among individuals with Duchenne muscular dystrophy (DMD) living in the United States are lacking. It is also unclear whether the association between glucocorticoid use and all-cause mortality persists in the context of other common treatments (cardiac medication, cough-assist, bilevel positive airway pressure, and scoliosis surgery) observed to delay mortality. Among 526 individuals identified by the Muscular Dystrophy Surveillance, Tracking, and Research Network, the estimated median survival time from birth was 23. Read More

J Fr Ophtalmol 2022 May 18. Epub 2022 May 18.

Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Hôpital gynéco-obstétrique et pédiatrique de Yaoundé, Yaoundé, Cameroun.

Purpose: To identify ocular abnormalities in premature children in order to treat reversible visual disorders and help prevent low vision and blindness in this population at risk.

Methodology: This was a cross-sectional, analytical study carried out from November 1, 2018 to July 31, 2019 at the Yaoundé Gyneco-Obstetric And Pediatric Hospital, including premature children, aged 3 to 15 years. The variables studied were age, sex, prenatal, birth and past ophthalmological history, visual acuity, oculomotor examination and fundus examination. Read More

Fertil Steril 2022 May 18. Epub 2022 May 18.

New York University Langone Prelude Fertility Center, New York, New York.

Objective: To review the outcomes of patients who underwent autologous oocyte thaw after planned oocyte cryopreservation.

Design: Retrospective cohort study.

Setting: Large urban university-affiliated fertility center. Read More

Am J Prev Med 2022 Jun 7;62(6):885-894. Epub 2022 Apr 7.

The Ciccarone Center for the Prevention of Cardiovascular Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland. Electronic address:

Introduction: Having a preterm birth is associated with future cardiovascular risk. Non-Hispanic Black women have higher rates of preterm birth than non-Hispanic White and Hispanic women, but nativity-related disparities in preterm birth are not well understood.

Methods: Data from 6,096 women in the Boston Birth Cohort: non-Hispanic Black (2,699), non-Hispanic White (997), or Hispanic (2,400), were analyzed in June 2021. Read More

Environ Pollut 2022 May 18:119481. Epub 2022 May 18.

Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, 200032, China; Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai, 200032, China. Electronic address:

Early pregnancy is crucial for fetal growth. Maternal thyroid hormone is critical for fetal growth and can be disturbed under exogenous exposure. However, it's uncertain whether exposure to PM and inorganic constituents during early pregnancy can affect TH and fetal growth. Read More

J Pediatr 2022 May 18. Epub 2022 May 18.

California Perinatal Quality Care Collaborative, Palo Alto, CA, United States; Stanford University School of Medicine Department of Pediatrics, Division of Neonatal and Developmental Medicine, Palo Alto, CA, United States.

Objective: To determine follow-up rates for the high-risk infant follow-up (HRIF) visit at 18-36 months among infants with very low birthweights (VLBW) and identify factors associated with completion.

Study Design: We completed a retrospective cohort study using linked California Perinatal Quality of Care Collaborative (CPQCC) neonatal intensive care unit (NICU), CPQCC California Children's Services HRIF, and Vital Statistics Birth Cohort databases. We identified maternal, sociodemographic, neonatal, clinical and HRIF program level factors associated with 18-36 month follow-up using multivariable Poisson regression. Read More

Biochem Biophys Res Commun 2022 May 13;615:1-8. Epub 2022 May 13.

Mental Health Center and Psychiatric Laboratory, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Converging lines of evidence suggest an association between schizophrenia and prenatal neurodevelopmental disorders. Preeclampsia is a multisystem disease based on the coexistence of pregnancy and elevated blood pressure, which increases the risk for offspring abnormal neurodevelopment. Previous studies have showed maternal preeclampsia is associated with an increased risk of offspring schizophrenia, but the molecular mechanism remains unclear. Read More

Eur J Obstet Gynecol Reprod Biol 2022 May 14;274:62-67. Epub 2022 May 14.

Tampere University Hospital, Department of Obstetrics and Gynecology, Tampere, Finland; Tampere University Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere, Finland.

Objectives: We analyzed the incidence of obese and severely obese parturients and the impact of maternal obesity on mode of delivery, perinatal and neonatal mortality, and neonatal health.

Study Design: We included all singleton births from the medical birth register of Finland from 2004 to 2018 (n = 792 437). Maternal body mass index (BMI) was categorized into three classes: non-obese (BMI < 30 kg/m), obese (BMI 30 - 39. Read More

J Glob Health 2022 May 21;12:04042. Epub 2022 May 21.

Burnet Institute, Melbourne, Australia.

Background: Maternal mental morbidity and low perinatal health service utilisation in resource-constrained settings contribute substantially to the global burden of poor maternal, newborn, and child health. The community-based Mbereko+Men program in rural Zimbabwe engaged women and men in complementary activities to improve men's support for women and babies, coparents' equitable, informed health decision-making, and ultimately, maternal mental health and care-seeking for maternal and newborn health services. The study aimed to test the effectiveness of the Mbereko+Men program on maternal mental health at 0-6 months after childbirth. Read More

Liver Int 2022 May 21. Epub 2022 May 21.

Division of Hepatology, Ospedale San Giuseppe MultiMedica IRCCS, Università degli Studi di Milano, Milan, Italy.

Vet Res Commun 2022 May 21. Epub 2022 May 21.

Estación Experimental Agropecuaria Salta, INTA, Cerrillos, 4403, Salta, Argentina.

The aim of this research was to evaluate the physiological and behavioural parameters in Saanen goat kids treated with flunixin meglumine compared with no analgesic treatment after cautery disbudding using a device fueled by propane gas. At 7 days of age, 30 goat kids were randomly allocated to three groups: Sham (Sh) control, (i.e. Read More

Arch Gynecol Obstet 2022 May 21. Epub 2022 May 21.

Division of Obstetrics and Prenatal Medicine, Department of Medicine and Surgery (DIMEC), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy, University of Bologna, Via Massarenti 13, 40138, Bologna, Italy.

Purpose: The aim of the study was to determine the cause-specific hazard (CSH) and the cumulative incidence function (CIF) for umbilical cord metabolic acidemia at birth (MA; pH < 7.0 and/or BE [Formula: see text] - 12 mmol/L) at delivery in patients experiencing the 2nd stage of labor (2STG), stratified for both FIGO-2015 pathologic intrapartum cardiotocography requiring expedited delivery (CTG_RED) and duration of 2nd stage of labor.

Methods: 3459 pregnancies experiencing the 2nd stage of labor and delivering at the Division of Obstetrics and Prenatal Medicine, IRCCS Sant'Orsola-Malpighi Hospital, Bologna (Italy), were identified between 2018 and 2019. Read More

Arch Gynecol Obstet 2022 May 21. Epub 2022 May 21.

Second Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, "Aretaieio" University Hospital, Athens, Greece.

Purpose: This systematic review is designed to summarize the evidence concerning the impact of maternal physical activity on the reproductive outcomes following assisted reproduction techniques (ART), namely in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI).

Methods: We searched for eligible studies on PubMed, EMBASE databases and the Cochrane Library from their inception until September 2021. Our primary outcomes were live birth rate and miscarriage, while secondary ones included clinical pregnancy and implantation rates. Read More

Arch Gynecol Obstet 2022 May 21. Epub 2022 May 21.

, Wiesenbacher Str. 10, 69151, Neckargemünd, Germany.

Purpose: This article presents a novel concept of the evolution and, thus, the pathogenesis of uterine adenomyosis as well as peritoneal and peripheral endometriosis. Presently, no unifying denomination of this nosological entity exists.

Methods: An extensive search of the literature on primate evolution was performed. Read More

BJOG 2022 May 21. Epub 2022 May 21.

Department of Obstetrics and Gynecology, Herlev University Hospital, Herlev, Denmark.

Background: There is increased focus on obstetric anal sphincter injury (OASI) and there are several well-established risk factors such as birth weight, instrumental delivery and median episiotomy. Some studies have found increased risk of OASI in women delivering vaginally after a previous caesarean section (VBAC).

Objective: To evaluate whether there is increased prevalence of OASI in VBAC compared to primiparous women. Read More

BJOG 2022 May 21. Epub 2022 May 21.

Hôpital universitaire Necker-Enfants malades, Obstetrics and fetal medicine, Paris, France.

Objective: To evaluate the effect of gestational age at laser therapy for twin-to-twin transfusion syndrome (TTTS) on perinatal outcome.

Design And Settings: Single retrospective observational cohort.

Population: All consecutive pregnancies affected by TTTS and referred to our department between January 2013 and August 2020. Read More

Birth Defects Res 2022 May 21. Epub 2022 May 21.

Corteva Agriscience™, Indianapolis, Indiana, USA.

Traditional developmental toxicity testing practice examines fetal apical endpoints to identify a point of departure (POD) for risk assessment. A potential new testing paradigm involves deriving a POD from a comprehensive analysis of molecular-level change. Here, the rat ketoconazole endocrine-mediated developmental toxicity model was used to test the hypothesis that maternal epigenomic (miRNA) and transcriptomic (mRNA) PODs are similar to fetal apical endpoint PODs. Read More

Endocrinology 2022 May 21. Epub 2022 May 21.

Department of Biochemistry University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas.

Using cultured human trophoblast stem cells (hTSCs), mid-gestation human trophoblasts in primary culture, and gene-targeted mice, we tested the hypothesis that the multinucleated syncytiotrophoblast (SynT) serves a critical role in pregnancy maintenance through production of key immune modulators/checkpoint proteins (ICPs) under control of the O2-regulated transcription factor, NRF2/NFE2L2. These ICPs potentially act at the maternal-fetal interface to protect the hemi-allogeneic fetus from rejection by the maternal immune system. Using cultured hTSCs, we observed that several ICPs involved in the induction and maintenance of immune tolerance were markedly upregulated during differentiation of cytotrophoblasts (CytT) to SynT. Read More

Indian Pediatr 2022 May 20. Epub 2022 May 20.

Department of Endocrinology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh. Correspondence to: Dr Rama Walia, Associate Professor, Endocrinology Office, Nehru Hospital Extension, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160 012.

Objective: To evaluate the anthropometric and pubertal outcomes, over a spectrum of treatment regimens and compliance.

Methods: We received records of the patients with classical CAH seen at the endocrinology clinic of a tertiary care center between 1995 and 2016.

Results: 25 females were included in the study, the majority (80%) with simple virilizing variant. Read More

J Obstet Gynaecol Res 2022 May 21. Epub 2022 May 21.

International Inpatient Department, Zhongshan Hospital Affiliated to Dalian University, Dalian City, Liaoning Province, China.

Background: To assess the independent risk factors and pregnancy outcomes of hypertensive disorders of pregnancy (HDPs) in Chinese advanced age pregnancy women.

Design: Secondary analysis of international published data.

Materials And Methods: PubMed, Web of Science, Scopus, Embase, Cochrane library, and Chinese databases from inception to February 23, 2022 were searched to identify eligible studies. Read More

BJOG 2022 May 20. Epub 2022 May 20.

Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.

Objective: To investigate whether intervening miscarriages and induced abortions impact the associations between interpregnancy interval after a live birth and adverse pregnancy outcomes.

Design: Population based cohort study.

Setting: Norway PARTICIPANTS: A total of 165,617 births to 143,916 women between 2008 and 2016 MAIN OUTCOME MEASURES: We estimated adjusted relative risks for adverse pregnancy outcomes using log-binomial regression, first ignoring miscarriages and induced abortions in the interpregnancy interval estimation (conventional interpregnancy interval estimates) and subsequently accounting for intervening miscarriages or induced abortions (correct interpregnancy interval estimates). Read More