Biomaterials 2021 Aug 31;277:121112. Epub 2021 Aug 31.
3B's Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Zona Industrial da Gandra, AvePark, Barco GMR, 4805-017, Portugal; ICVS/3B's, PT Government Associate Laboratory, Braga, Guimarães, Portugal. Electronic address:
Natural extracellular matrix governs cells providing biomechanical and biofunctional outstanding properties, despite being porous and mostly made of soft materials. Among organs, specific tissues present specialized macro-architectures. For instance, hepatic lobules present radial organization, while vascular sinusoids are branched from vertical veins, providing specific biofunctional features. Read More