Pharmaceutics 2021 Apr 29;13(5). Epub 2021 Apr 29.
Department of Chemistry, Federal University of Santa Maria, Santa Maria 97105-900, Brazil.
Imidazolium-based dicationic ILs (DILs) presenting antimicrobial activity and relatively low toxicity are highly desirable and are envisioned for use in live tissue to prevent bacterial or fungal infections. In this context, we present here DILs with dicarboxylate anions [C(MIM)[C(MIM)][CO-(CH)CO], in which = 4, 6, 8, and 10, and m = 0, 1, 2, 3, 4, and 5. The results showed that DILs with an alkyl chain spacer of ten carbons were active against yeasts and the bacterial strains tested. Read More