26,854 results match your criteria bilateral optic

Surgical success of lateral rectus resection for residual and recurrent esotropia.

Int Ophthalmol 2021 Jun 15. Epub 2021 Jun 15.

Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Purpose: To assess the surgical outcomes of reoperations for residual and recurrent esotropia.

Methods: A retrospective chart review of all patients who underwent surgery during 2000-2017 at a tertiary referral medical center for recurrent or residual esotropia was conducted. Patients who underwent bilateral medial rectus recession as primary surgery and lateral rectus resection as second surgery were included. Read More

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Use of Soft Contact Lens for Esthetic and Functional Rehabilitation.

Eye Contact Lens 2021 07;47(7):383-387

Eye Department of Contat lenses (P.P.Y. and V.F.S.), Hospital Sadalla Amin Ghanem, Joinville, SC, Brazil; Department of Ophthalmology (S.A.S.), Medical School, State University of Sao Paulo-UNESP, Botucatu, SP, Brazil; and Department of Biostatistic (C.R.P.), Biosciences Institute, State University of Sao Paulo-UNESP, Botucatu, SP, Brazil.

Objective: To report the outcomes and complications of colored soft contact lenses (SCLs) to improve esthetic or eye function in visually impaired (VI) or blind patients.

Methods: This retrospective study enrolled consecutive patients with unilateral or bilateral VI or blindness who had received colored SCLs to improve appearance or ocular function. Data were collected on demographics, complaints, complete ophthalmological examinations, types of SCL, follow-ups, and complications. Read More

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COVID-19 Associated Bilateral Acute Iris Transillumination.

Ocul Immunol Inflamm 2021 Jun 14:1-3. Epub 2021 Jun 14.

Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.

: To report a case of bilateral acute iris transillumination (BAIT) in association with coronavirus disease 2019 (COVID-19).: A 44-year-old woman patient presented with decreased visual acuity, pain, photophobia, and redness in both eyes. The patient reported that she had recent close contact with severe acute respiratory syndrome - coronavirus-2 (SARS-CoV-2) case; also, she mentioned that she was hospitalized for bilateral pneumonia for 14 days. Read More

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Leber Hereditary Optic Neuropathy: Review of Treatment and Management.

Front Neurol 2021 26;12:651639. Epub 2021 May 26.

Neuro-ophthalmology Department, Hôpital Fondation Rothschild, Paris, France.

Leber hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disease that specifically targets the retinal ganglion cells by reducing their ability to produce enough energy to sustain. The mutations of the mitochondrial DNA that cause LHON are silent until an unknown trigger causes bilateral central visual scotoma. After the onset of loss of vision, most patients experience progressive worsening within the following months. Read More

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The Novel KIF1A Missense Variant (R169T) Strongly Reduces Microtubule Stimulated ATPase Activity and Is Associated With NESCAV Syndrome.

Front Neurosci 2021 26;15:618098. Epub 2021 May 26.

Genetics Laboratory, UDIAT-Centre Diagnòstic, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Spain.

KIF1A is a microtubule-dependent motor protein responsible for fast anterograde transport of synaptic vesicle precursors in neurons. Pathogenic variants in have been associated with a wide spectrum of neurological disorders. Here, we report a patient presenting a severe neurodevelopmental disorder carrying a novel missense variant p. Read More

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Macula hole as a sequelae of presumed ocular toxoplasmosis, an incidental finding in a female Nigerian: Case report and review of literature.

Y O Babalola

Niger J Clin Pract 2021 Jun;24(6):959-963

Department of Ophthalmology, University College Hospital/University of Ibadan, Ibadan, Nigeria.

A 39-year-old Nigerian woman presented to the eye clinic for a new pair of spectacles on account of a two-week history of headaches and bilateral eye ache. She was a known spectacle wearer for the past nine years. The presenting visual acuity was 6/6 and 6/36, respectively, in the right and left eye. Read More

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Myelin Oligodendrocyte Glycoprotein-antibody-associated Disorder Presenting with Corticomeningeal Encephalitis prior to the Onset of Optic Neuritis.

Intern Med 2021 Jun 12. Epub 2021 Jun 12.

Department of Neurology, Oita University, Japan.

We herein report a case of myelin oligodendrocyte glycoprotein-antibody-associated disorder (MOG-AD) presenting with corticomeningeal encephalitis. The patient exhibited oral ulceration, a mild impairment of consciousness, fever, nausea, nuchal rigidity, positivity for human leukocyte antigen type B51, and neutrophil-dominant pleocytosis and interleukin-6 level in cerebrospinal fluid (CSF). Magnetic resonance imaging (MRI) revealed a right temporal lesion with leptomeningeal gadolinium enhancement. Read More

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[Blepharyplasty as treatment of chronic headache].

Ugeskr Laeger 2021 Jun;183(24)

Hemicrania continua (HC) is a primary chronic headache disorder characterised with a broad range of autonomic symptoms. In this case report a 29-year-old patient was bothered by appearance of a unilateral sharp pain located behind the right eye at the same spot where the headache usually was located. He was diagnosed with HC and treated with indomethacin with good effect. Read More

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Monocular central retinal artery occlusion caused by bilateral internal carotid artery hypoplasia complicated with patent foramen ovale: a case report and review of literature.

Eur J Med Res 2021 Jun 13;26(1):55. Epub 2021 Jun 13.

Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, China.

Background: Central retinal artery occlusion (CRAO) is an emergent ophthalmic disease which is commonly caused by atherosclerosis, thromboembolism, and arteriospasm. Here, we report a case of CRAO which is caused by extreme rare bilateral internal carotid artery (ICA) hypoplasia complicated with patent foramen ovale (PFO). The cardiogenic emboli blocked central retinal artery through unclosed foramen ovale and specific blood flow pathway. Read More

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Higher functional connectivity between prefrontal regions and the dorsal attention network predicts absence of renewal.

Behav Brain Res 2021 Jun 10;412:113413. Epub 2021 Jun 10.

Department of Neurology, BG University Hospital Bergmannsheil, Ruhr-University Bochum, Germany.

Renewal describes the recovery of an extinguished response when extinction and recall contexts differ, demonstrating the context-dependency of extinction. The unexpected outcome change during extinction presumably directs attention to the context and promotes renewal. Accordingly, studies show that context processing for renewal is modulated by salience of and attention to context. Read More

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Long-tevrm outcomes of the MICOF keratoprosthesis surgery.

Ocul Surf 2021 Jun 9;21:178-185. Epub 2021 Jun 9.

Department of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China. Electronic address:

Purpose: To evaluate long-term anatomical and functional outcomes of the MICOF keratoprosthesis to treat end-stage corneal blindness.

Design: Retrospective review of consecutive clinical case series.

Participants: Between October 2000 and October 2015, at the Department of Ophthalmology of Chinese PLA General Hospital (PLAGH), a total of 132 eyes of 131 patients had undergone a MICOF keratoprosthesis implantation. Read More

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Five year results of a prospective, randomised, contralateral eye trial of corneal crosslinking for keratoconus.

Clin Exp Ophthalmol 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, University of Auckland, Auckland, New Zealand.

Background: Few studies have evaluated corneal crosslinking in a prospective, randomised fashion. This study aimed to determine the efficacy and safety of corneal crosslinking to reduce the progression of keratoconus.

Methods: Prospective, unmasked, randomised, contralateral eye controlled trial at a tertiary eye centre. Read More

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Demography, clinical profile and surgical outcomes of paediatric giant retinal tear related retinal detachments.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Objective: To determine the demographic profile, clinical features and surgical outcomes of giant retinal tear (GRT) related retinal detachments (RD) in children.

Methods: In this retrospective study, medical records of children aged 14 years and below, who underwent surgery for RD at our centre in the last 5 years were reviewed. Among these, we selected medical records of children with RDs with GRT, and examined the coloured retinal drawings, ultrawidefield photographs and/or surgical videos. Read More

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Transconjunctival versus transcutaneous local anaesthetic administration for lower eyelid surgery: a randomised controlled trial.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, Mater Misericordiae University Hospital, Dublin 7, Ireland.

Aim: To compare the associated discomfort and safety between transcutaneous (Tskin) and transconjunctival (Tconj) approaches of local anaesthetic (LA) administration in lower eyelid surgery.

Methods: A prospective randomised controlled trial comparing Tskin and Tconj LA in patients undergoing bilateral lower eyelid surgeries for horizontal laxity. Patients were randomised to receive LA via Tskin to one side and Tconj to the fellow side. Read More

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Clinical outcomes with a low add multifocal and an extended depth of focus intraocular lenses both implanted with mini-monovision.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey.

Objectives: To compare the visual acuity, contrast sensitivity (CS), spectacle needs, photic phenomena, and quality of life parameters of patients bilaterally implanted with a low add multifocal (MIOL) or an extended depth of focus (EDOF) intraocular lens (IOL), both with intended mini-monovision.

Methods: In this prospective, randomized, comparative study, patients were randomized to receive either Tecnis +2.75 D (ZKB00) (MIOL Group, n = 15) or Tecnis Symfony (ZXR00) (EDOF Group, n = 14) for bilateral implantation with mini-monovision (-0. Read More

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Non-infectious uveitis affecting the posterior segment treated with fluocinolone acetonide intravitreal implant: 3-year fellow eye analysis.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, St. Franziskus Hospital Muenster, Muenster, Germany.

Background: Prevention of non-infectious uveitis of the posterior segment (NIU-PS) recurrence using 0.2 μg/day fluocinolone acetonide implant (FAi) was assessed over 3 years (NCT01694186). Outcomes for FAi-treated and fellow eyes with NIU-PS were compared, to evaluate FAi versus conventional treatment strategies. Read More

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Clinical Outcomes of New Monofocal Intraocular Lenses with Enhanced Intermediate Function Compared with Extended Depth of Focus Intraocular Lenses.

J Cataract Refract Surg 2021 Jun 7. Epub 2021 Jun 7.

Department of Ophthalmology, HanGil Eye Hospital, Incheon, South Korea. Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea Department of Ophthalmology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, South Korea.

Purpose: To compare clinical outcomes of a new monofocal intraocular lens (IOL) with enhanced intermediate function and an extended-depth-of-focus (EDOF) IOL.

Setting: Asan Medical Center, Seoul, Korea.

Design: Nonrandomized prospective comparative case series. Read More

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A Case Report of Subclinical Myasthenia Gravis Associated with Castleman's Disease.

Am J Case Rep 2021 Jun 11;22:e930948. Epub 2021 Jun 11.

Department of Thoracic Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

BACKGROUND Castleman's disease is defined as a benign lymphoproliferative disorder of uncertain origin. It is most commonly found in the area of mediastinum. Castleman's disease is classified based on pathological features into hyaline-vascular, plasma cell, and mixed variants, which the hyaline-vascular variant is the commonest in association with Myasthenia Gravis. Read More

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Pachychoroid Spectrum Disease: Underlying Pathology, Classification, and Phenotypes.

Curr Eye Res 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.

Purpose: Pachychoroid spectrum disease encompasses a set of macular disorders secondary to an abnormally thick choroid. However, the pathological process underlying pachychoroid spectrum disease and its overlap with age-related macular degeneration (AMD) remain unclear. This review aimed to understand the underlying pathology, classification, and phenotypes of pachychoroid spectrum disease. Read More

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Early Surgical Intervention for Neovascular Glaucoma in a Patient with Diabetes.

Cureus 2021 Jun 3;13(6):e15420. Epub 2021 Jun 3.

Ophthalmology Department, Salmaniya Medical Complex, Manama, BHR.

Neovascular glaucoma (NVG) is a cause of blindness in patients with proliferative diabetic retinopathy (PDR) and remains a clinical challenge. It results from vascular endothelial growth factor (VEGF) expression, which occurs in cases of severe retinal ischemia. Early detection and immediate comprehensive management, including early surgical intervention, are essential to maintain good intraocular pressure (IOP) control and achieve the best visual outcome, as presented in this case. Read More

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Neuro-Ophthalmological Findings as First Manifestation of Occipital Tuberculoma.

Neuroophthalmology 2021 17;45(2):120-125. Epub 2020 Jul 17.

Ophthalmology Residents.

We present a 54-year-old male garbage collector, who came to the ophthalmology department due to one-month history of bilateral blurred vision, palinopsia, headache and visual geometrical hallucinations. The examination showed a normal anterior segment, a homonymous left upper central scotoma and tilted segmental hypoplasia of the optic nerve of the left eye. Contrast-enhanced brain magnetic resonance imaging showed a mass lesion in the right occipital cortex. Read More

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The Effect of Congenital and Acquired Bilateral Anophthalmia on Brain Structure.

Neuroophthalmology 2021 1;45(2):75-86. Epub 2021 Mar 1.

Oxford Eye Hospital, John Radcliffe Hospital, Oxford, UK.

The aim of this study was to compare the pattern of changes in brain structure resulting from congenital and acquired bilateral anophthalmia. Brain structure was investigated using 3T magnetic resonance imaging (MRI) in Oxford (congenital) or Manchester (acquired). T1-weighted structural and diffusion-weighted scans were acquired from people with anophthalmia and sighted control participants. Read More

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Surgical membranectomy with modified incision and capsulotomy microscissors for persistent pupillary membrane.

Ann Palliat Med 2021 May;10(5):5619-5626

Shenzhen Eye Hospital, Shenzhen Eye Hospital affiliated to Jinan University, School of Optometry, Shenzhen University, Shenzhen, China.

Background: To evaluate the visual outcome and complications of surgical membranectomy with modified incision and capsulotomy microscissors in patients with persistent pupillary membrane (PPM).

Methods: We enrolled eight eyes with PPM in six patients and performed surgical membranectomy with modified incision located near the limbus and corresponding to the middle of the densest membrane strands. Strands near the collarette of the iris were then cut using capsulotomy microscissors and thick strands were removed with capculorhexis forceps. Read More

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The Impact of Hearing Experience on Children's Use of Phonological and Semantic Information During Lexical Access.

J Speech Lang Hear Res 2021 Jun 9:1-20. Epub 2021 Jun 9.

Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.

Purpose The purpose of this study was to examine the extent to which phonological competition and semantic priming influence lexical access in school-aged children with cochlear implants (CIs) and children with normal acoustic hearing. Method Participants included children who were 5-10 years of age with either normal hearing ( = 41) or bilateral severe to profound sensorineural hearing loss and used CIs ( = 13). All participants completed a two-alternative forced-choice task while eye gaze to visual images was recorded and quantified during a word recognition task. Read More

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Intra-arterial chemotherapy for treatment of very low birthweight infants with retinoblastoma: Two case reports.

Medicine (Baltimore) 2021 May;100(19):e25870

Department of Interventional Radiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Introduction: Intra-arterial chemotherapy (IAC) has been used successfully for unilateral and bilateral eye disease with advanced or less advanced intraocular disease and of children as young as 3 months of age. In this study, we expanded the use of IAC to eyes of two infants with very low birthweight (birth weight of 1000-1500 g) and retinoblastoma.

Patient Concerns: The ophthalmologists refused to give patients intravenous chemotherapy (IVC), considering the risk of IVC because of the low body weight. Read More

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Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis in a COVID-19 patient: A case report.

Medicine (Baltimore) 2021 May;100(19):e25865

Department of Ophthalmology, University of Yamanashi, Chuo, Yamanashi.

Rationale: Coronavirus disease 2019 (COVID-19) has spread worldwide. It involves multiple organs of infected individuals and encompasses diverse clinical manifestations. We report a case of acute optic neuritis (ON) associated with myelin oligodendrocyte glycoprotein (MOG) antibody possibly induced by COVID-19. Read More

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Clinical and Morphologic Characteristics of ERK Inhibitor-Associated Retinopathy.

Ophthalmol Retina 2021 Jun 5. Epub 2021 Jun 5.

Ophthalmic Oncology Service; Department of Medicine.

Purpose: Investigate clinical and morphologic characteristics of serous retinal disturbances in patients taking extracellular signal-regulated kinase (ERK) inhibitors.

Participants: Of 61 patients receiving ERK inhibitors for treatment of metastatic cancer, this study included 40 eyes of 20 patients with evidence of retinopathy confirmed by optical coherence tomography (OCT).

Design: Single center, retrospective study of prospectively collected data METHODS: Clinical exam, fundus photography and OCT were used to evaluate ERK inhibitor retinopathy. Read More

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Cerebellitis in a human T-lymphotropic virus type 1 carrier: a case report.

BMJ Case Rep 2021 Jun 7;14(6). Epub 2021 Jun 7.

Department of Neurology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.

Human T-lymphotropic virus type I (HTLV-I) is a retrovirus associated with adult T-cell lymphoma (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). In addition to HAM/TSP and ATL, HTLV-I-associated encephalopathy and cerebellar involvement have been reported. We report a case of an 87-year-old Japanese woman presenting with progressive dysarthria and gait disturbance. Read More

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"Neuroimaging in ethambutol induced optic neuropathy: MRI in time can save the vision".

Indian J Tuberc 2021 Jul 18;68(3):408-411. Epub 2020 Sep 18.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.

Ethambutol is an integral part of Antitubercular therapy (ATT) and is often associated with optic neuropathy, However, neuroimaging of ethambutol induced optic neuropathy has been sparsely reported in the literature. We describe the case of a 45-year male patient, diagnosed as Tuberculous spondylodiscitis and was on ATT. Four months after ATT initiation, he presented with visual blurring in both the eyes with bitemporal hemianopia and central scotomas. Read More

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[A family of renal coloboma syndrome].

C Y Li J Xiao

Zhonghua Yan Ke Za Zhi 2021 Jun;57(6):454-457

Department of Ophthalmology, Second Affiliated Hospital, Jilin University, Changchun 130012, China.

The proband was a 5-year-old boy with binocular esotropia since childhood. Ocular examination showed the binocular optic cup was wide and deep excavated with radial emergence of the retinal vessels and retinal detachment was seen in the left eye. The father of the proband with worse vision of the right eye from a child and received a kidney transplant 10 years ago. Read More

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