5 results match your criteria biebersteinia multifida

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Gastro-protective effect of root hydro-methanolic extract in rats with ethanol-induced peptic ulcer.

Avicenna J Phytomed 2019 Sep-Oct;9(5):410-418

Division of Pharmacology and Toxicology, Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

Objective: is one of the native plants of Iran and its root is used in folk medicine. This study aimed to evaluate the gastro-protective effect of the hydro-methanolic extract of this plant's roots against ethanol-induced gastric ulcer in rats.

Materials And Methods: The following five groups of seven rats were included in this study: control (C), gastric ulcer (GU), control omeprazole (CO) and two treatment groups (the latter 3 groups were rats with gastric ulcer that orally received omeprazole, 20 mg/kg, or the root extract at 150 and 300 mg/kg (BM 150 and BM 300, respectively) 1 hour before ulcer induction). Read More

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September 2019

Effects of hydro-ethanol extract on proliferation and apoptosis of human prostate cancer and human embryonic kidney cells.

Avicenna J Phytomed 2016 Nov-Dec;6(6):671-677

Pharmacological Research Centre of Medicinal Plants, School of Medicine, Mashhad, University of Medical Sciences, Mashhad, Iran.

Objective: (Geraniaceae) has a history of use in traditional medicine in some countries including Iran. In the present study, cytotoxic and apoptogenic properties of hydro-ethanol extract of was investigated on human prostate cancer cell lines (PC3 and DU 145) and human embryonic kidney 293 (HEK293) cells.

Materials And Methods: Cells were cultured in RPMI-1640 medium supplemented with 10% FBS at 37ºC in a humidified atmosphere of 95% air and 5% CO. Read More

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January 2017

Coumarin compounds of Biebersteinia multifida roots show potential anxiolytic effects in mice.

Daru 2013 Jun 27;21(1):51. Epub 2013 Jun 27.

Background: Traditional preparations of the root of Biebersteinia multifida DC (Geraniaceae), a native medicinal plant of Irano-Turanian floristic region, have been used for the treatment of phobias as anxiolytic herbal preparation.

Methods: We utilized the phobic behavior of mice in an elevated plus-maze as a model to evaluate the anxiolytic effect of the plant extract and bio-guided fractionation was applied to isolate the active compounds. Total root extract, alkaline and ether fraction were administered to mice at different doses 30 and 90 min prior to the maze test. Read More

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Antihemolytic and antioxidant activities of Biebersteinia multifida.

Eur Rev Med Pharmacol Sci 2010 Oct;14(10):823-30

Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

Objectives: Biebersteinia multifida is a common herb known in Iran. Its roots have been used locally in folk medicine of western region of Iran in the treatment of many diseases. The antioxidant activity and its inhibition of erythrocyte hemolysis were investigated. Read More

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October 2010

Anti-inflammatory and analgesic activity of Biebersteinia multifida DC. root extract.

J Ethnopharmacol 2000 Aug;71(3):443-7

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, 14155-6451, Tehran, Iran.

The root of Biebersteinia multifida DC (Geraniaceae), a native plant of Iran, has been used topically for the treatment of musculoskeletal disorders as a folk medicine. The anti-inflammatory and analgesic effects of the root extract were studied using carrageenan induced edema and formalin tests. A similar activity was seen between Biebersteinia multifida root extract (10 mg/kg; i. Read More

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