Behav Brain Res 2021 Apr 24;409:113319. Epub 2021 Apr 24.
Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230022, China; School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230022, China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, 230022, China. Electronic address:
Autistic traits are highly heritable and characterized by social deficits. Common genetic variants of the autism-related CNTNAP2 gene have been linked with social impairments, but the neural substrates are poorly understood. In the present study, we investigated the genetic effect of common variants of CNTNAP2 (rs2710102 and rs7794745) on gray matter volume and its association with social performance among 442 healthy participants. Read More