15,986 results match your criteria bears


J Parasitol 2021 May;107(3):519-528

Department of Microbiology, University of Tennessee, Knoxville, Tennessee 37996-0845.

Toxoplasma gondii infections are common in humans and animals worldwide. The present review summarizes worldwide information on the prevalence of clinical and subclinical infections, epidemiology, and genetic diversity of T. gondii infections in bears. Read More

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Mobility of the forearm skeleton in the Asiatic black (Ursus thibetanus), brown (U. arctos) and polar (U. maritimus) bears.

J Vet Med Sci 2021 Jun 24. Epub 2021 Jun 24.

Hokkaido University School of Veterinary Medicine and Obihiro University of Agriculture and Veterinary Medicine, Cooperative Veterinary Education Program, Hokkaido University.

In several primates and carnivores, pronation/supination angles of the forearm skeleton were examined, and it is thought that a larger angle is useful to acquire dexterous behaviors in feeding and/or life style, including climbing. In this study, the pronation/supination angles in Asiatic black, brown and polar bears were nondestructively examined. These specimens were classified as adult or non-adult. Read More

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Impact of a Remote Monitoring Programme Including Lifestyle Education Software in Type 2 Diabetes: Results of the [email protected] Randomised Multicentre Study.

Diabetes Ther 2021 Jun 23. Epub 2021 Jun 23.

Department of Diabetology, Metabolic Diseases and Nutrition, University Hospital of Toulouse, 1 Avenue Jean Poulhès, TSA 50032, Toulouse cedex 9, 31059, Toulouse, France.

Introduction: Telemonitoring in type 2 diabetes (T2D) is mainly based on glucose monitoring. A new type of connected device which routinely gathers data on weight, physical activity and food intake could improve patients' diabetes control. The main aim of this study was to assess the efficacy of an at-home interventional programme incorporating such devices and lifestyle education software on diabetes control, i. Read More

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Nitroxides as Building Blocks for Nanoantioxidants.

ACS Appl Mater Interfaces 2021 Jun 22. Epub 2021 Jun 22.

Department of Chemistry "Giacomo Ciamician", University of Bologna, via Selmi 2, 40126 Bologna, Italy.

Nitroxides are an important class of radical trapping antioxidants whose promising biological activities are connected to their ability to scavenge peroxyl (ROO) radicals. We have measured the rate constants of the reaction with ROO () for a series of 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) derivatives as 5.1 × 10, 1. Read More

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Intraspecific variation in the Cambrian: new observations on the morphology of the Chengjiang euarthropod Sinoburius lunaris.

BMC Ecol Evol 2021 06 21;21(1):127. Epub 2021 Jun 21.

Faculty of Biology, Ludwig-Maximilians-Universität München, 82152, Planegg-Martinsried, Germany.

Background: The Chengjiang biota from southwest China (518-million-years old, early Cambrian) has yielded nearly 300 species, of which more than 80 species represent early chelicerates, crustaceans and relatives. The application of µCT-techniques combined with 3D software (e.g. Read More

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Measuring breathing induced oesophageal motion and its dosimetric impact.

Phys Med 2021 Jun 18;88:9-19. Epub 2021 Jun 18.

Division of Medical Physics, Department of Radiation Oncology, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; German Cancer Consortium (DKTK). Partner Site Freiburg, Germany.

Purpose: Stereotactic body radiation therapy allows for a precise dose delivery. Organ motion bears the risk of undetected high dose healthy tissue exposure. An organ very susceptible to high dose is the oesophagus. Read More

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Dynamics of MHC-I molecules in the antigen processing and presentation pathway.

Curr Opin Immunol 2021 Jun 18;70:122-128. Epub 2021 Jun 18.

Center for Computational and Genomic Medicine, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA. Electronic address:

The endogenous antigen processing and presentation (APP) is a fundamental pathway found in jawed vertebrates, which allows for a set of epitope peptides sampled from the intracellular proteome to be assembled and displayed on class I proteins of the major histocompatibility complex (MHC-I). Peptide/MHC-I antigens enable different aspects of adaptive immunity to emerge, by providing a basis for recognition of self vs. non-self by T cells and Natural Killer (NK) cells. Read More

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SARS-CoV-2-Host Chimeric RNA-Sequencing Reads Do Not Necessarily Arise From Virus Integration Into the Host DNA.

Front Microbiol 2021 2;12:676693. Epub 2021 Jun 2.

Retroviral Immunology, The Francis Crick Institute, London, United Kingdom.

The human genome bears evidence of extensive invasion by retroviruses and other retroelements, as well as by diverse RNA and DNA viruses. High frequency of somatic integration of the RNA virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the DNA of infected cells was recently suggested, based on a number of observations. One key observation was the presence of chimeric RNA-sequencing (RNA-seq) reads between SARS-CoV-2 RNA and RNA transcribed from human host DNA. Read More

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A light-oxygen-voltage receptor integrates light and temperature.

J Mol Biol 2021 Jun 16:167107. Epub 2021 Jun 16.

Department of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany; Biophysical Chemistry, Humboldt-University Berlin, 10115 Berlin, Germany; Bayreuth Center for Biochemistry & Molecular Biology, Universität Bayreuth, 95447 Bayreuth, Germany; North-Bavarian NMR Center, Universität Bayreuth, 95447 Bayreuth, Germany. Electronic address:

Sensory photoreceptors enable organisms to adjust their physiology, behavior, and development in response to light, generally with spatiotemporal acuity and reversibility. These traits underlie the use of photoreceptors as genetically encoded actuators to alter by light the state and properties of heterologous organisms. Subsumed as optogenetics, pertinent approaches enable regulating diverse cellular processes, not least gene expression. Read More

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[Towards freedom to claim the right to die].

Soins Psychiatr 2021 May-Jun;42(334):28-31. Epub 2021 Apr 21.

Université Claude-Bernard Lyon 1, 43 boulevard du 11-Novembre-1918, 69100 Villeurbanne, France; Unité de recherche clinique intersectorielle, service de psychiatrie adulte, CHRU de Brest, hôpital de Bohars, route de Ploudalmézeau, 29280 Bohars, France; Soins primaires, Santé publique, registre des cancers de Bretagne occidentale, EA 7479, université de Bretagne occidentale, 22 rue Camille-Desmoulins, CS 93837, 29238 Brest cedex 3, France.

current evolution of society makes it possible to debate the issue of the end of life for people suffering from pathologies in which the vital prognosis is not involved; this concerns psychiatric situations in particular. This debate, which bears the seeds of a real desire to die as a personal choice, is likely to profoundly modify the doctor-patient relationship in the particular field of psychiatry. Read More

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Carbon neutral manufacturing via on-site CO recycling.

iScience 2021 Jun 4;24(6):102514. Epub 2021 May 4.

Cambridge Centre for Advanced Research and Education in Singapore, CARES Ltd. 1 CREATE Way, CREATE Tower #05-05, 138602 Singapore, Singapore.

The chemical industry needs to significantly decrease carbon dioxide (CO) emissions in order to meet the 2050 carbon neutrality goal. Utilization of CO as a chemical feedstock for bulk products is a promising way to mitigate industrial emissions; however, CO-based manufacturing is currently not competitive with the established petrochemical methods and its deployment requires creation of a new value chain. Here, we show that an alternative approach, using CO conversion as an add-on to existing manufactures, can disrupt the global carbon cycle while minimally perturbing the operation of chemical plants. Read More

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Multisource noninvasive genetics of brown bears () in Greece reveals a highly structured population and a new matrilineal contact zone in southern Europe.

Ecol Evol 2021 Jun 2;11(11):6427-6443. Epub 2021 May 2.

NERC Biomolecular Analysis Facility Department of Animal and Plant Sciences University of Sheffield UK.

In human-dominated landscapes, connectivity is crucial for maintaining demographically stable mammalian populations. Here, we provide a comprehensive noninvasive genetic study for the brown bear population in the Hellenic Peninsula. We analyze its population structuring and connectivity, estimate its population size throughout its distribution, and describe its phylogeography in detail for the first time. Read More

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Can offsetting the energetic cost of hibernation restore an active season phenotype in grizzly bears (Ursus arctos horribilis)?

J Exp Biol 2021 Jun 17;224(12). Epub 2021 Jun 17.

School of Biological Sciences, College of Arts and Sciences, Washington State University, Pullman, WA 99164, USA.

Hibernation is characterized by depression of many physiological processes. To determine if this state is reversible in a non-food caching species, we fed hibernating grizzly bears (Ursus arctos horribilis) dextrose for 10 days to replace 53% or 100% of the estimated minimum daily energetic cost of hibernation. Feeding caused serum concentrations of glycerol and ketones (β-hydroxybutyrate) to return to active season levels irrespective of the amount of glucose fed. Read More

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Functional conservation and divergence of SEPALLATA-like genes in the development of two-type florets in marigold.

Plant Sci 2021 Aug 15;309:110938. Epub 2021 May 15.

Key Laboratory of Horticultural Plant Biology, Ministry of Education, College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Shizishan Street No. 1, Wuhan, 430070, China; Key Laboratory of Urban Agriculture in Central China (Pilot Run), Ministry of Agriculture, Wuhan, 430070, China. Electronic address:

Marigold (Tagetes erecta), as one member of Asteraceae family, bears a typical capitulum with two morphologically distinct florets. The SEPALLATA genes are involved in regulating the floral meristem determinacy, organ identity, fruit maturation, seed formation, and plant architecture. Here, five SEP-like genes were cloned and identified from marigold. Read More

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Self-consistent model of the plasma staircase and nonlinear Schrödinger equation with subquadratic power nonlinearity.

Phys Rev E 2021 May;103(5-1):052218

CEA-Cadarache, IRFM, F-13108 Saint-Paul-lez-Durance cedex, France.

A new basis has been found for the theory of self-organization of transport avalanches and jet zonal flows in L-mode tokamak plasma, the so-called "plasma staircase" [Dif-Pradalier et al., Phys. Rev. Read More

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Folliculocystic and Collagen Hamartoma: A Subset of Fibrous Cephalic Plaque.

Cureus 2021 May 12;13(5):e14987. Epub 2021 May 12.

Dermatopathology, Skin Cancer and Dermatology Institute, Reno, USA.

Tuberous sclerosis complex is known to cause a variety of cutaneous hamartomas, most commonly hypomelanotic macules, angiofibromas, shagreen patches, and fibrous cephalic plaques. In recent years, a new cutaneous hamartoma that bears physical and histological resemblance to fibrous cephalic plaque has been proposed called folliculocystic and collagen hamartoma. The primary difference between the two diagnoses is the histologic presence of infundibular cysts in the latter. Read More

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Spin pinning effect to reconstructed oxyhydroxide layer on ferromagnetic oxides for enhanced water oxidation.

Nat Commun 2021 Jun 15;12(1):3634. Epub 2021 Jun 15.

School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore.

Producing hydrogen by water electrolysis suffers from the kinetic barriers in the oxygen evolution reaction (OER) that limits the overall efficiency. With spin-dependent kinetics in OER, to manipulate the spin ordering of ferromagnetic OER catalysts (e.g. Read More

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A programmable chemical switch based on triggerable Michael acceptors.

Chem Sci 2020 Jan 10;11(8):2103-2111. Epub 2020 Jan 10.

Department of Chemistry, University of Massachusetts Amherst Massachusetts 01003 USA

Developing an engineerable chemical reaction that is triggerable for simultaneous chemical bond formation and cleavage by external cues offers tunability and orthogonality which is highly desired in many biological and materials applications. Here, we present a chemical switch that concurrently captures these features in response to chemically and biologically abundant and important cues, , thiols and amines. This thiol/amine-triggerable chemical switch is based on a Triggerable Michael Acceptor (TMAc) which bears good leaving groups at its β-position. Read More

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January 2020

Synthesis, conformational analysis and assays of an anti-cancer vaccine that features an unnatural antigen based on an sp-iminosugar fragment.

Chem Sci 2020 Mar 27;11(15):3996-4006. Epub 2020 Mar 27.

Departamento de Química, Universidad de La Rioja, Centro de Investigación en Síntesis Química E-26006 Logroño Spain

The Tn antigen (GalNAc-α-1--Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides that incorporate this structure has become a significant and promising niche of research owing to their potential use as anticancer vaccines. Herein, the conformational preferences of a glycopeptide with an unnatural Tn antigen, characterized by a threonine decorated with an sp-iminosugar-type α-GalNAc mimic, have been studied both in solution, by combining NMR spectroscopy and molecular dynamics simulations, and in the solid state bound to an anti-mucin-1 (MUC1) antibody, by X-ray crystallography. Read More

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Heteroleptic Ligation by an endo-Functionalized Cage.

Angew Chem Int Ed Engl 2021 Jun 14. Epub 2021 Jun 14.

Georg-August-Universität Göttingen, Institut für Anorganische Chemie, Institut für Anorganische Chemie, Tammannstraße 4, 37077, Göttingen, GERMANY.

A conceptual approach for the synthesis of quasiheteroleptic complexes with properly endo-functionalized cages as ligands is presented. The cage ligand reported here is of a covalent organic nature, it has been synthesized via a dynamic combinatorial chemistry approach, making use of a masked amine. Inspired by enzymatic active sites the described system bears one carboxylate and two imidazole moieties as independent ligating units through which it is able to coordinate to transition metals. Read More

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Adaptive optics enhanced sensitivity in Fabry-Pérot based photoacoustic tomography.

Photoacoustics 2021 Sep 21;23:100276. Epub 2021 May 21.

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

All-optical ultrasound detection bears a number of unique advantages for photoacoustic tomography, including the ability for high resolution sampling of the acoustic field and its compatibility with a wide variety of other optical modalities. However, optical schemes based on miniaturized cavities are sensitive to optical aberrations as well as manufacturing-induced cavity imperfections which degrade sensor sensitivity and deteriorate photoacoustic image quality. Here we present an experimental method based on adaptive optics that is capable of enhancing the overall sensitivity of Fabry-Pérot based photoacoustic sensors. Read More

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September 2021

Rubbing behavior of European brown bears: factors affecting rub tree selectivity and density.

J Mammal 2021 Apr 29;102(2):468-480. Epub 2021 Jan 29.

Research Unit of Biodiversity (UMIB, CSIC-UO-PA), Mieres Campus, Mieres, Spain.

Scent-mediated communication is considered the principal communication channel in many mammal species. Compared with visual and vocal communication, odors persist for a longer time, enabling individuals to interact without being in the same place at the same time. The brown bear (), like other mammals, carries out chemical communication, for example, by means of scents deposited on marking (or rub) trees. Read More

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An engineering perspective on the development and evolution of implantable cardiac monitors in free-living animals.

Philos Trans R Soc Lond B Biol Sci 2021 Aug 14;376(1830):20200217. Epub 2021 Jun 14.

Department of Surgery, University of Minnesota, B172 Mayo, MMC 195, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

The latest technologies associated with implantable physiological monitoring devices can record multiple channels of data (including: heart rates and rhythms, activity, temperature, impedance and posture), and coupled with powerful software applications, have provided novel insights into the physiology of animals in the wild. This perspective details past challenges and lessons learned from the uses and developments of implanted biologgers designed for human clinical application in our research on free-ranging American black bears (). In addition, we reference other research by colleagues and collaborators who have leveraged these devices in their work, including: brown bears (), grey wolves (), moose (), maned wolves () and southern elephant seals (). Read More

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The effect of parenting pressure on children's internalizing problem behaviors and its mechanism.

Jing Zou

Work 2021 Jun 6. Epub 2021 Jun 6.

Background: in the process of raising children, parents will inevitably have inappropriate measures and behaviors, which will bring greater pressure on the children's psychology and physiology.

Objective: in the field of children's development, parenting pressure has always been one of the hotspots of worldwide scholars. In order to further understand the causes of children's psychological problems, the effect of parenting pressure on children's internalizing problem behaviors and its mechanism are explored. Read More

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Phylogenetic Identification of Symbiotic Protists of Five Chinese Reticulitermes Species Indicates a Cospeciation of Gut Microfauna with Host Termites.

J Eukaryot Microbiol 2021 Jun 13:e12862. Epub 2021 Jun 13.

Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Institute of Entomology, Central China Normal University, Wuhan, 430079, P. R. China.

Symbiotic protists play important roles in the wood digestion of lower termites. Previous studies showed that termites generally possess host-specific flagellate communities. The genus Reticulitermes is particularly interesting because its unique assemblage of gut flagellates bears evidence for transfaunation. Read More

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Big food and the World Health Organization: a qualitative study of industry attempts to influence global-level non-communicable disease policy.

BMJ Glob Health 2021 06;6(6)

Tobacco Control Research Group, Department for Health, University of Bath, Bath, UK.

Introduction: There is an urgent need for effective action to address the over 10 million annual deaths attributable to unhealthy diets. Food industry interference with policies aimed at reducing non-communicable diseases (NCDs) is widely documented at the national level but remains under-researched at the global level. Thus, this study explores how ultra-processed food industry actors have attempted to influence NCD policy at WHO. Read More

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Genetic and pathogenic characterization of a novel recombinant avian infectious bronchitis virus derived from GI-1, GI-13, GI-28, and GI-19 strains in Southwestern China.

Poult Sci 2021 Apr 29;100(7):101210. Epub 2021 Apr 29.

Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science Sichuan University, Chengdu 610064, China. Electronic address:

Avian infectious bronchitis (IB), caused by avian infectious bronchitis virus (IBV), is an acute and highly contagious disease that is extremely harmful to the poultry industry throughout the world. The cross-using of different attenuated live vaccine strains has led to the occurrence of diverse IBV serotypes. In this study, we isolated an IBV strain from a chicken farm in southwest China and designated it CK/CH/SCMY/160315. Read More

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Gravitational scaling analysis on spatial diffusion of COVID-19 in Hubei Province, China.

PLoS One 2021 11;16(6):e0252889. Epub 2021 Jun 11.

Department of Geography, College of Urban and Environmental Sciences, Peking University, Beijing, P.R. China.

The spatial diffusion of epidemic disease follows distance decay law in geography and social physics, but the mathematical models of distance decay depend on concrete spatio-temporal conditions. This paper is devoted to modeling spatial diffusion patterns of COVID-19 stemming from Wuhan city to Hubei province, China. The modeling approach is to integrate analytical method and experimental method. Read More

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Electronic Structure and Electron Delocalization in Bare and Dressed Boron Pentamer Clusters.

J Phys Chem A 2021 Jun 11;125(24):5246-5255. Epub 2021 Jun 11.

Kimika Fakultatea, Euskal Herriko Unbertsitatea (UPV/EHU), Donostia International Physics Center (DIPC), P.K. 1072, 20080 Donostia, Euskadi, Spain.

The electronic structures of the lowest energy spin-states of the cationic, neutral and anionic bare boron pentamer clusters have been investigated by means of high level multiconfigurational type calculations, in view of the large static and dynamical electron correlation effects for these species. We found that resembles a singlet spin-state perfect pentagon, which bears no intra-annular chemical bonding interactions, as shown by our analysis of the electron delocalization carried out in terms of the normalized Giambiagi ring-current index, and the total and adjacent atom-pair delocalization indices. However, its lowest-energy triplet and quintet spin-state isomers have symmetry, with large intra-annular chemical bonding interactions. Read More

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Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from sv. .

iScience 2021 May 29;24(5):102480. Epub 2021 Apr 29.

Center of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.

Lanthipeptides, ribosomally synthesized and post-translationally modified peptides (RiPPs), can be divided into five classes based on their structures and biosynthetic pathways. Class I and II lanthipeptides have been well characterized, whereas less is known about members of the other three classes. Here, we describe a new family of class III lanthipeptides from . Read More

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