11,751 results match your criteria basilar artery

[Collateral circulation pathway in patients with basilar artery occlusion/severe stenosis: a single-center case series].

Zhonghua Nei Ke Za Zhi 2021 Aug;60(8):734-738

Department of Neurology, the Sixth Medical Center of PLA General Hospital, Beijing 100048, China.

To investigate the collateral circulation compensation model in patients with favorable prognosis of basilar artery occlusion/severe stenosis treated with drugs or endovascular therapy. Clinical data of patients with basilar artery occlusion/severe stenosis and good clinical outcome were retrospectively collected in the Department of Neurology, Sixth Medical Center of PLA General Hospital from January 2019 to January 2020. They were divided into intensive drug therapy group and combined endovascular therapy group. Read More

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Commentary on "Endovascular Therapy for Stroke Due to Basilar-Artery Occlusion".

Kornelia Kreiser

Cardiovasc Intervent Radiol 2021 Jul 20. Epub 2021 Jul 20.

Departement of Radiology/Neuroradiology, RKU - Universitäts- und Rehabilitationskliniken Ulm gGmbH, Oberer Eselsberg 45, 89081, Ulm, Germany.

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The Analysis of Morphoradiological Parameters in Predicting Risk of Basilar Artery Tip Aneurysm Rupture: A Retrospective Cohort Study.

Int J Gen Med 2021 12;14:3335-3342. Epub 2021 Jul 12.

College of Medicine, Imam Abdulrahman Bin Faisal University, King Fahd Hospital of the University, Al-Khobar City, Eastern Province, Saudi Arabia.

Purpose: Basilar artery tip aneurysms can have fatal consequences and poor prognostic outcomes in case of rupture. We investigated the standard parameters used to evaluate aneurysmal morphology to predict aneurysm rupture.

Patients And Methods: We measured the differences between ruptured and unruptured basilar bifurcation aneurysms in terms of morphological features, including aneurysm size, size ratio, aneurysm height, perpendicular height, aneurysm width, bottleneck ratio, aspect ratio, and present daughter domes, using 3D angiography. Read More

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Cerebral Arterial Bifurcations Harboring D Type Aneurysm are more Asymmetrical than those with C Type Aneurysm.

J Stroke Cerebrovasc Dis 2021 Jul 15;30(9):105972. Epub 2021 Jul 15.

Center of Medical Research, Shijiazhuang People's Hospital, Fangbei Road, Shijiazhuang, Hebei Province 050011, China. Electronic address:

Objectives: This study was designed to determine aneurysm deviation and to compare anatomical differences of bifurcations harboring C and D-type aneurysms.

Materials And Methods: A total of 198 arterial bifurcations harboring aneurysms were enrolled in this study, including 58 anterior cerebral arteries (ACAs), 64 middle cerebral arteries (MCAs), 19 basilar arteries (BAs), and 57 internal carotid artery-posterior communicating arteries (ICA-PComAs). Aneurysms were defined as C type if the neck was located on the extension of the parent artery midline and D type if it was not, then, aneurysm deviation was examined. Read More

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Vertebral artery V3 portion-radial artery-distal common carotid artery (V3-RA-dCCA) bypass for large basilar trunk aneurysm with bilateral proximal common carotid artery occlusion-technical note.

Acta Neurochir (Wien) 2021 Jul 17. Epub 2021 Jul 17.

Department of Neurological Surgery, Nippon Medical School, Bunkyo City, Japan.

Background: Large basilar trunk aneurysm caused by bilateral occlusion of the proximal common carotid artery is rare. We treated one case with vertebral V3 portion-radial artery-distal common carotid artery (V3-RA-dCCA) bypass.

Case Description: Basilar trunk aneurysm and bilateral occlusion of the proximal CCA were found incidentally in a 70-year-old woman. Read More

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Huge Fenestration of the Vertebral Artery and Fenestrated Basilar Artery.

J Craniofac Surg 2021 Jul 15. Epub 2021 Jul 15.

Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy National Institute of Neurology and Neurovascular Diseases Division of Anatomy, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

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Monocyte to High-Density Lipoprotein Ratio Is Associated With Early Neurological Deterioration in Acute Isolated Pontine Infarction.

Front Neurol 2021 28;12:678884. Epub 2021 Jun 28.

Department of Neurology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.

The monocyte to high-density lipoprotein ratio (MHR) has been considered to be a novel inflammatory marker of atherosclerotic cardiovascular disease. However, its role in the acute phase of acute isolated pontine infarctions remains elusive. We explored whether an association existed between elevated MHR levels and early neurological deterioration (END) in patients with isolated pontine infarction. Read More

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Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells.

Biomed Pharmacother 2021 Jul 7;139:111615. Epub 2021 May 7.

Department of Pharmacology, Shanxi Medical University, Xinjiannanlu 56, Taiyuan 030001, Shanxi Province, China. Electronic address:

Background: Severe acidosis deteriorates cardiac injury. Rat coronary arteries (RCAs) are unusually hypercontractive to extracellular (o) acidosis (EA). TMEM16A-encoded anoctamin 1 (ANO1), a Ca-activated chloride channel (CaCC), plays an important role in regulating coronary arterial tension. Read More

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Plasma Homocysteine and Prognosis of Patients with Recanalization after Acute Basilar Artery Occlusion: An Analysis from the Acute Basilar Artery Occlusion Study (BASILAR) Nationwide Prospective Registry.

Curr Neurovasc Res 2021 Jul 7. Epub 2021 Jul 7.

Department of Neurology, Affiliated Hospital of North Sichuan Medical College, 63 Wenhua Road, Nanchong 637000, China.

Background: Few studies have investigated the association between plasma homocysteine (Hcy) levels in patients with recanalization after acute basilar artery occlusion (BAO).

Objective: This study investigated the predictive value of Hcy on the clinical prognosis of patients with recanalization after acute BAO.

Methods: Altogether, 829 participants were recruited from the standard medical treatment plus endovascular treatment group of the Acute Basilar Artery Occlusion Study (BASILAR). Read More

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[Basilar skull fractures].

Josef Mohamad

Radiologe 2021 Jul 8. Epub 2021 Jul 8.

Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße 1, 66424, Homburg/Saar, Deutschland.

Clinical Issue: Basilar skull fractures are fractures of the lower part of the skull. They make up about 20% of all skull fractures and are mainly caused by high-velocity blunt trauma and falls from high heights. Depending on their precise location, they can be divided into frontobasal, laterobasal and frontolateral fractures. Read More

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Acute basilar artery occlusion (BAO): a pictorial review of multimodal imaging findings.

Emerg Radiol 2021 Jul 7. Epub 2021 Jul 7.

Department of Radiology and Diagnostic Imaging, Fundación Clínica Shaio, Bogotá, D.C., Colombia.

Acute basilar artery occlusion (BAO) is an uncommon cause of stroke; however, it constitutes a serious medical emergency and is associated with elevated mortality rates as well as unfavorable functional outcomes. This is especially true when it is not rapidly diagnosed, and the initiation of reperfusion therapies is delayed. Its etiology is mainly embolic or atherosclerotic, and it often presents with non-specific signs and symptoms (e. Read More

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Locked-In Syndrome after Traumatic Basilar Artery Entrapment within a Clivus Fracture: A Case Report and Review of the Literature.

Neurotrauma Rep 2020 14;1(1):73-77. Epub 2020 Sep 14.

Department of Neurology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

We report the case of a 58-year-old male with a rare vascular complication after traumatic head injury: entrapment of the basilar artery into a fracture of the clivus, ultimately leading to a locked-in syndrome due to brainstem infarction. Review of the literature revealed 19 earlier published cases of basilar artery entrapment within traumatic longitudinal clival fractures. In the majority of these patients there is an unfavorable neurological outcome. Read More

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September 2020

Therapeutic effect of and mechanisms underlying the effect of miR-195-5p on subarachnoid hemorrhage-induced vasospasm and brain injury in rats.

PeerJ 2021 22;9:e11395. Epub 2021 Jun 22.

Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

Objectives: There is much evidence suggesting that inflammation contributes majorly to subarachnoid hemorrhage (SAH)-induced cerebral vasospasm and brain injury. miRNAs have been found to modulate inflammation in several neurological disorders. This study investigated the effect of miR-195-5p on SAH-induced vasospasm and early brain injury in experimental rats. Read More

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Flow diverter-coil technique for endovascular treatment of complex wide neck brain aneurysms, Technical point.

Caspian J Intern Med 2021 Apr;12(3):350-355

Department of Surgery, Babol University of Medical Sciences, Babol, Iran.

Background: Treatment of complex wide neck brain aneurysms is a challenging era in neurosurgery. Both surgical and endovascular therapies are considered for treatment of them. In endovascular, there are different ways such as trapping, coiling, stent and balloon assisted coiling. Read More

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Morphologic characterization of the posterior inferior cerebellar artery. A direct anatomic study.

Folia Morphol (Warsz) 2021 Jul 5. Epub 2021 Jul 5.

Department of Basic Sciences, Medicine School, Universidad Industrial de Santander, Bucaramanga, Colombia.

Background: The study of the cerebellar arteries has increased. The purpose of this study was to determine the morphological expression of posterior inferior cerebellar artery in a sample of Colombian population.

Materials And Methods: 186 posterior inferior cerebellar arteries of fresh cadavers were studied. Read More

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Persistent trigeminal artery as a rare cause of vertebrobasilar insufficiency.

Folia Morphol (Warsz) 2021 Jul 5. Epub 2021 Jul 5.

Department of General and Interventional Radiology and Neuroradiology, Borowska 213, 50-556 Wrocław.

The persistent trigeminal artery (PTA) is the most common fetal carotid- basilar anastomosis which may persist into adult life. In the literature there are numerous papers referring to the anatomical characteristics of this anomalous vessel. In the majority of cases PTA is an incidental finding and its clinical significance has been debated. Read More

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Local Hemodynamic Changes Immediately after Correction of an Aberrant Right Subclavian Artery in a Dog: A Contrast Computed Tomographic Study.

Vet Sci 2021 Jun 8;8(6). Epub 2021 Jun 8.

Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoinooka, Imabari, Ehime 794-8555, Japan.

A 1-year-old female Akita dog was referred for intermittent regurgitation. Computed tomographic angiography (CTA) showed an aberrant right subclavian artery (ARSA), resulting in constriction of the esophagus. After surgical ligation of the ARSA, CTA showed that the ARSA was not enhanced by contrast medium, and that sufficient collateral circulation of the right forelimb was supplied through the vertebral artery. Read More

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Oxidative Stress Mediates Vascular Tortuosity.

Antioxidants (Basel) 2021 Jun 7;10(6). Epub 2021 Jun 7.

Department of Neurosurgery, Graduate School of Medicine, Hirosaki University, 5-Zaifuchou, Hirosaki, Aomori 036-8562, Japan.

Vascular tortuosity is associated with various disorders and is being increasingly detected through advances in imaging techniques. The underlying mechanisms for vascular tortuosity, however, remain unclear. Here, we tested the hypothesis that oxidative stress mediates the generation of tortuous vessels. Read More

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Changes in Cerebral Blood Flow after Erenumab Treatment in Good and Non-Responders-A Pilot Study of Migraine Patients.

J Clin Med 2021 Jun 7;10(11). Epub 2021 Jun 7.

Department of Sensory Organs Examination, Faculty of Health Sciences, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, M. Skłodowskiej-Curie 9, 85-090 Bydgoszcz, Poland.

Erenumab showed efficacy in migraine prevention, however we cannot identify which patients to treat by predicting efficacy response. The aim of this study was to compare changes in cerebral blood flow (CBF) reflected by transcranial Doppler (TCD) in erenumab good responders (GR) and non-responders, in order to identify a parameter that could predict the treatment response. In this study, migraineurs treated with erenumab underwent clinical and TCD evaluations before and 6 weeks after the treatment, including data on migraine type, monthly migraine days (MMD), medication overuse headache (MOH) presence, mean blood flow velocity (Vm) and pulsatility index (PI) in cerebral arteries (CA). Read More

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Does stroke etiology influence outcome in the posterior circulation? An analysis of 107 consecutive acute basilar occlusion thrombectomies.

Neurosurg Focus 2021 Jul;51(1):E7

Objective: Acute basilar artery occlusion (BAO) harbors a more guarded prognosis after thrombectomy compared with anterior circulation large-vessel occlusion. Whether this is a function of a greater proportion of atherosclerotic/intrinsic lesions is not well studied. The authors aimed to elucidate the prevalence and predictors of intracranial intrinsic atherosclerotic disease in patients with acute BAO and to compare angiographic and clinical outcomes between patients with BAO secondary to embolic versus intrinsic disease. Read More

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Comparison of effectiveness and outcomes among different thrombectomy techniques in acute basilar artery occlusion: a dual-center experience.

Neurosurg Focus 2021 Jul;51(1):E8

Departments of1Neurosurgery.

Objective: Acute basilar artery occlusion (BAO) is a rare large-vessel occlusion associated with high morbidity and mortality. Modern thrombectomy with stent retrievers and large-bore aspiration catheters is highly effective in achieving recanalization, but a direct comparison of different techniques for acute BAO has not been performed. Therefore, the authors sought to compare the technical effectiveness and clinical outcomes of stent retriever-assisted aspiration (SRA), aspiration alone (AA), and a stent retriever with or without manual aspiration (SR) for treatment of patients presenting with acute BAO and to evaluate predictors of clinical outcome in their cohort. Read More

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Xiaoxuming Decoction Regulates Vascular Function by Modulating G Protein-Coupled Receptors: A Molecular Docking Study.

Biomed Res Int 2021 5;2021:5575443. Epub 2021 Jun 5.

Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Xiaoxuming decoction (XXMD) is a traditional Chinese herbal medicine (CHM) that is used for the treatment of stroke in China. Stroke injury damages the cerebral vasculature and disrupts the autoregulation of vasoconstriction and vasodilatation, which is crucial for maintaining constant cerebral blood flow (CBF). It has been reported that XXMD exerts a positive effect on cerebral circulation in animal models of stroke. Read More

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Hemodynamic Effects of Size and Location of Basilar Artery Fenestrations Associated to Pathological Implications.

Int J Numer Method Biomed Eng 2021 Jun 28:e3507. Epub 2021 Jun 28.

School of Life Science, Beijing Institute of Technology, Beijing, China.

Fenestration is a rare congenital abnormality that refers to a segmental duplication of arteries. It is still not clear about the role of fenestrations in the etiology and pathological evolution of vascular diseases. This study aims to investigate the hemodynamic influence brought by various sizes and locations of fenestration in basilar artery models. Read More

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Vertebrobasilar Contribution to Cerebral Arterial System of Dromedary Camels ().

Front Vet Sci 2021 11;8:696707. Epub 2021 Jun 11.

College of Veterinary Medicine, School of Veterinary and Life Sciences, Murdoch University, Perth, WA, Australia.

It is hypothesized that in the "more highly evolved" mammals, including the domesticated mammals, that the brainstem and the cerebellum receive arterial blood through the vertebrobasilar system whilst the internal carotid arteries primarily supply the forebrain. In camels, the arterial blood supply to the brain differs from that of ruminants since the internal carotid artery and the rostral epidural rete mirabile (RERM) are both present and the basilar artery contributes a significant proportion of cerebral afferent blood. In this study, we described the anatomical distribution of the vertebrobasilar system arterial supply in the dromedary. Read More

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Evaluation of Endovascular Treatment for Acute Basilar Occlusion in a State-Wide Prospective Stroke Registry.

Front Neurol 2021 11;12:678505. Epub 2021 Jun 11.

Department of Neurology, University Hospital/ Goethe University Frankfurt, Frankfurt, Germany.

Despite overwhelming evidence for endovascular therapy in anterior circulation ischemic stroke due to large-vessel occlusion, data regarding the treatment of acute basilar artery occlusion (BAO) are still equivocal. The BASICS trial failed to show an advantage of endovascular therapy (EVT) over best medical treatment (BMT). In contrast, data from the recently published BASILAR registry showed a better outcome in patients receiving EVT. Read More

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Prognostic Structural Neural Markers of MRI in Response to Mechanical Thrombectomy for Basilar Artery Occlusion.

Front Neurol 2021 9;12:593914. Epub 2021 Jun 9.

Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.

Mechanical thrombectomy (MT) has been an effective first-line therapeutic strategy for ischemic stroke. With impairment characteristics separating it from anterior circulation stroke, we aimed to explore prognostic structural neural markers for basilar artery occlusion (BAO) after MT. Fifty-four BAO patients with multi-modal magnetic resonance imaging at admission from the multicenter real-world designed BASILAR research were enrolled in this study. Read More

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Distal Basilar Artery "Umbrella Aneurysm" Treated by Radial Artery Graft Bypass From the External Carotid Artery to Posterior Cerebral Artery and Clip Trapping: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 Jun 25. Epub 2021 Jun 25.

Department of Neurological Surgery, University of Washington, Seattle, Washington, USA.

A 71-yr-old woman was discovered to have an incidental distal basilar artery (BA) fusiform aneurysm 7 × 5 mm in dimension, shaped like an "umbrella handle" with critical stenosis distal to the aneurysm. The right posterior cerebral artery (PCA) P1 segment was small; the left posterior communicating artery (PComA) was miniscule. Because the natural history of fusiform BA aneurysms is poorly defined, this was equated to a saccular aneurysm, with an estimated 10-yr rupture rate of 29%. Read More

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Variations in foramen transversarium of cervical spine: an osteological study in dried cervical vertebra of North Indian origin with its surgical importance.

Turk Neurosurg 2021 Jan 20. Epub 2021 Jan 20.

All India Institute of Medical Sciences, Department of Anatomy, Bathinda, India.

Aim: Foramina transversaria (FT) are located on the transverse process of cervical vertebrae. These foramina are known to exhibit variations with regard to shape, size and may even absent, incomplete or duplicated. The aim of this study was to investigate the variations in number, shape, size of foramina transversaria of the human cervical vertebrae and their clinical importance Material and Methods: 200 dry cervical vertebrae (C3-C7) of 40 spines were studied for the presence of variations in number, size and shape of the FT. Read More

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January 2021

A Volumetric Metric for Monitoring Intracranial Aneurysms: Repeatability and Growth Criteria in a Longitudinal MR Imaging Study.

AJNR Am J Neuroradiol 2021 Jun 24. Epub 2021 Jun 24.

Departments of Radiology and Biomedical Imaging, and Epidemiology and Biostatistics (X.L., H.H., Y.W., E.K., M.B., A.J.M., C.E.M., F.F., D.S), University of California San Francisco, San Francisco, Californa.

Background And Purpose: The reliability of contrast-enhanced MRA in monitoring serial volumetric changes of unruptured intracranial aneurysms has not been established. We aimed to determine the coefficient of variance of contrast-enhanced MRA in measuring aneurysm volumes, thus establishing criteria for aneurysm growth and permitting identification of variables predictive of growth.

Materials And Methods: Aneurysm volumes were measured from serial contrast-enhanced MRA studies of patients with untreated intracranial aneurysms who underwent >2 sequential MR imaging evaluations. Read More

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Cerebral large artery stenosis and occlusion in POEMS syndrome.

BMC Neurol 2021 Jun 24;21(1):239. Epub 2021 Jun 24.

Department of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, 260-8677, Chiba, Japan.

Background: This study aimed to investigate the frequency and risk factors for cerebral artery stenosis and occlusion in patients with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome.

Methods: We reviewed results of magnetic resonance angiography (MRA) or computed tomography angiography (CTA) in 61 patients with POEMS syndrome seen between 2010 and 2017. Stenosis or occlusion was assessed in the initial MRA/CTA. Read More

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