Int J Pharm 2021 Jul 27:120952. Epub 2021 Jul 27.
Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Tr. T. Bati 5678, 76001, Zlin, Czech Republic; Footwear Research Centre, University Institute, Tomas Bata University in Zlin, Nad Ovcirnou IV, 3685, Zlin, Czech Republic; Faculty of Technology, Tomas Bata University in Zlin, Vavrečkova 275, 76001 Zlin, Czech Republic.
In this study, an antimicrobial mumio-based hydrogel dressing was developed for wound healing application. The mechanism of gel formation was achieved via a double crosslink network formation between gelatin (GT) and polyvinyl alcohol (PVA) using polyethylene glycol diglycidyl ether (PEGDE) and borax as crosslinking agents. To enhance the mechanical integrity of the hydrogel matrix, bacterial cellulose (BC) was integrated into the GT-PVA hydrogel to produce a composite gel dressing. Read More