1,239,248 results match your criteria bacterial


A novel computational framework for genome-scale alternative transcription units prediction.

Brief Bioinform 2021 May 6. Epub 2021 May 6.

School of Mathematics, Shandong University, Jinan 250200, China.

Alternative transcription units (ATUs) are dynamically encoded under different conditions and display overlapping patterns (sharing one or more genes) under a specific condition in bacterial genomes. Genome-scale identification of ATUs is essential for studying the emergence of human diseases caused by bacterial organisms. However, it is unrealistic to identify all ATUs using experimental techniques because of the complexity and dynamic nature of ATUs. Read More

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Potential biotransformation pathways and efficiencies of ciprofloxacin and norfloxacin by an activated sludge consortium.

Sci Total Environ 2021 Apr 27;785:147379. Epub 2021 Apr 27.

Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin 300350, PR China; SynBio Research Platform, Collaborative Innovation Centre of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin 300350, PR China. Electronic address:

Fluoroquinolones (FQs), such as ciprofloxacin (CIP) and norfloxacin (NOR), are types of emerging trace pollutants that have attracted great attention. In this study, an activated sludge (AS) consortium with high bio-removal capability to CIP and NOR was obtained by acclimating with CIP and NOR for 10 d. Meanwhile, a CIP- and NOR- transforming bacterial strain (S5), which is highly homologous to the 16S rRNA gene sequence of Enterobacter sp. Read More

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Enhanced diversity and rock-weathering potential of bacterial communities inhabiting potash trachyte surface beneath mosses and lichens - A case study in Nanjing, China.

Sci Total Environ 2021 Apr 26;785:147357. Epub 2021 Apr 26.

Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture, College of Life Science, Nanjing Agricultural University, Nanjing 210095, PR China.

Mosses and lichens have been shown to play an important role in enhancing global chemical weathering of the surface rock. However, there are no studies concerning the effects of mosses and lichens on the microbial communities inhabiting rock surfaces. In this study, culture-dependent and culture-independent analyses were employed to compare the diversity, composition, and rock-weathering activity of bacterial communities inhabiting potash trachyte surfaces covered by mosses (MR) and lichens (LR) with those inhabiting surrounding bare rock surfaces (BR). Read More

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COVID-19 influences lung microbiota dynamics and favors the emergence of rare infectious diseases: A case report of Hafnia Alvei pneumonia.

J Crit Care 2021 Apr 18;64:173-175. Epub 2021 Apr 18.

Dipartimento di Scienze dell' Emergenza, Anestesiologiche e della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Facoltà di medicina e chirurgia "A. Gemelli", Università Cattolica del Sacro Cuore, Rome, Italy.

The coronavirus disease 2019 causes a wide degree of organ dysfunction and is associated with bacterial secondary infections. We reported lung microbiota dynamics in a critically ill patient with coronavirus disease 2019, who developed severe Hafnia alvei ventilator-associated pneumonia and required extracorporeal membrane oxygenation support. Read More

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Lycium barbarum mitigates radiation injury via regulation of the immune function, gut microbiota, and related metabolites.

Biomed Pharmacother 2021 May 3;139:111654. Epub 2021 May 3.

Tianjin University of Traditional Chinese Medicine, Tianjin, China; Beijing Institute of Radiation Medicine, Beijing, China. Electronic address:

Previous studies have suggested that Lycium barbarum (L. barbarum) has a radioprotective function, although more in-depth investigation is still required. We investigated the radioprotective efficacy of extract of the fruits of L. Read More

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A novel bimetallic (Fe/Bi)-povidone-iodine micro-flowers composite for photocatalytic and antibacterial applications.

J Photochem Photobiol B 2021 Apr 28;219:112204. Epub 2021 Apr 28.

Advanced Ceramics and Nanotechnology Laboratory, Department of Materials Engineering, Faculty of Engineering, University of Concepción, Concepción 4070409, Chile.

The present work describes the synthesis of polyvinylpyrrolidone (PVP) assisted Fe-BiOI based Fe/Bi-povidone‑iodine (Fe/Bi-P-I) micro-flowers based composite and its photocatalytic and antibacterial applications. The Fe/Bi-P-I micro-flowers-based composite material was synthesized using a simple co-precipitation method. The prepared Fe/Bi-P-I micro-flowers-based composite materials were characterized using various characterization techniques and tested against photocatalytic degradation of rhodamine B (RhB) dye and antibacterial analysis. Read More

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Metabolic engineering of Bacillus subtilis for enhancing riboflavin production by alleviating dissolved oxygen limitation.

Bioresour Technol 2021 Apr 29;333:125228. Epub 2021 Apr 29.

Key Laboratory of Industrial Biotechnology of the Ministry of Education, Laboratory of Applied Microorganisms and Metabolic Engineering, School of Biotechnology, Jiangnan University, Wuxi 214122, China. Electronic address:

Riboflavin, an essential vitamin for animals, is used widely in the pharmaceutical industry and as a food and feed additive. The microbial synthesis of riboflavin requires a large amount of oxygen, which limits the industrial-scale production of the vitamin. In this study, a metabolic engineering strategy based on transcriptome analysis was identified as effective in increasing riboflavin production. Read More

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Surface-enhanced Raman spectroscopy for the identification of tigecycline-resistant E. coli strains.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 24;258:119831. Epub 2021 Apr 24.

Department of Chemistry, University of Agriculture Faisalabad, Faisalabad 38040, Pakistan.

Tigecycline (TGC) is recognised as last resort of drugs against several antibiotic-resistant bacteria. Bacterial resistance to tigecycline due to presence of plasmid-mediated mobile TGC resistance genes (tet X3/X4) has broken another defense line. Therefore, rapid and reproducible detection of tigecycline-resistant E. Read More

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δ-MnO changed the structure of humic-like acid during co-composting of chicken manure and rice straw.

Waste Manag 2021 May 3;128:16-24. Epub 2021 May 3.

College of Life Science, Northeast Agricultural University, Harbin 150030, China.

Improving the structure and quantity of humus is important to reduce agriculture organic waste by composting. The present study was aimed to assess the role of δ-MnO on humus fractions formation during co-composting of chicken manure and rice straw. Two tests (control group (CK), the addition of δ-MnO (M)) were carried out. Read More

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Extracellular polymeric substances induced cell-surface interactions facilitate bacteria transport in saturated porous media.

Ecotoxicol Environ Saf 2021 May 3;218:112291. Epub 2021 May 3.

Department of Soil and Water Sciences, China Agricultural University, Beijing 100193, China. Electronic address:

Bacteria often respond to dynamic soil environment through the secretion of extracellular polymeric substances (EPS). The EPS modifies cell surface properties and soil pore-scale hydration status, which in turn, influences bacteria transport in soil. However, the effect of soil particle size and EPS-mediated surface properties on bacterial transport in the soil is not well understood. Read More

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Synergistic inactivation of bacteria based on a combination of low frequency, low-intensity ultrasound and a food grade antioxidant.

Ultrason Sonochem 2021 Apr 16;74:105567. Epub 2021 Apr 16.

Department of Food Science and Technology, University of California, Davis, CA, USA; Department of Biological and Agricultural Engineering, University of California, Davis, CA, USA. Electronic address:

This study evaluated a synergistic antimicrobial treatment using a combination of low frequency and a low-intensity ultrasound (LFU) and a food-grade antioxidant, propyl gallate (PG), against a model gram-positive (Listeria innocua) and the gram-negative bacteria (Escherichia coli O157:H7). Bacterial inactivation kinetic measurements were complemented by characterization of biophysical changes in liposomes, changes in bacterial membrane permeability, morphological changes in bacterial cells, and intracellular oxidative stress upon treatment with PG, LFU, and a combination of PG + LFU. Combination of PG + LFU significantly (>4 log CFU/mL, P < 0. Read More

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Evaluation of different antigenic preparations against necrotic enteritis in broiler birds using a novel Clostridium perfringens type G strain.

Anaerobe 2021 May 3:102377. Epub 2021 May 3.

Department of Microbiology, College of Veterinary Science, AAU., Khanapara, Guwahati, Assam, India. Electronic address:

Objective: Keeping in view, the constraints faced by the Indian broiler industry with lack of a suitable vaccine against Necrotic Enteritis (NE), a study has been proposed to explore the prevalence and detail characterization of C. perfringens type G in NE suspected broiler chicken in the process of suitable vaccine development.

Methods: Intestinal scrapings/faecal contents of NE suspected broiler chickens were screened to establish the prevalence of C. Read More

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The role of genetic manipulation and in situ modifications on production of bacterial nanocellulose: A review.

Int J Biol Macromol 2021 May 3. Epub 2021 May 3.

Department of Chemistry, Middle East Technical University, 06800 Çankaya, Ankara, Turkey.

Natural polysaccharides are well-known biomaterials because of their availability and low-cost, with applications in diverse fields. Cellulose, a renowned polysaccharide, can be obtained from different sources including plants, algae, and bacteria, but recently much attention has been paid to the microorganisms due to their potential of producing renewable compounds. In this regard, bacterial nanocellulose (BNC) is a novel type of nanocellulose material that is commercially synthesized mainly by Komagataeibacter spp. Read More

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Survivability and controlled release of alginate-microencapsulated Pseudomonas fluorescens VUPF506 and their effects on biocontrol of Rhizoctonia solani on potato.

Int J Biol Macromol 2021 May 3. Epub 2021 May 3.

Department of Plant Protection, Faculty of Agricultural Sciences, Vali-e-Asr University of Rafsanjan, Iran.

Preserving the efficacy of plant probiotic bacteria in soil is a major challenge to the biological control of plant diseases. The microencapsulation technique is an important step in preserving the viability and activity of probiotics in adverse environmental conditions. The main objective of this study was to choose an appropriate coating for probiotic encapsulation. Read More

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Rapid in vitro prototyping of O-methyltransferases for pathway applications in Escherichia coli.

Cell Chem Biol 2021 May 4. Epub 2021 May 4.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

O-Methyltransferases are ubiquitous enzymes involved in biosynthetic pathways for secondary metabolites such as bacterial antibiotics, human catecholamine neurotransmitters, and plant phenylpropanoids. While thousands of putative O-methyltransferases are found in sequence databases, few examples are functionally characterized. From a pathway engineering perspective, however, it is crucial to know the substrate and product ranges of the respective enzymes to fully exploit their catalytic power. Read More

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Ultrathin, Strong, and Highly Flexible TiCT MXene/Bacterial Cellulose Composite Films for High-Performance Electromagnetic Interference Shielding.

ACS Nano 2021 May 6. Epub 2021 May 6.

School of Materials Science and Engineering, Key Laboratory of Advanced Ceramics and Machining Technology (Ministry of Education), and Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300072, China.

The fabrication of ultrathin films that are electrically conductive and mechanically strong for electromagnetic interference (EMI) shielding applications is challenging. Herein, ultrathin, strong, and highly flexible TiCT MXene/bacterial cellulose (BC) composite films are fabricated by a scalable biosynthesis method. The TiCT MXene nanosheets are uniformly dispersed in the three-dimensional BC network to form a mechanically entangled structure that endows the MXene/BC composite films with excellent mechanical properties (tensile strength of 297. Read More

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Presence of biogenic amines in food and their public health concerns.

J Food Prot 2021 May 6. Epub 2021 May 6.

University of Van Yȕzȕncȕ Yıl, Veterinary College, Department of Food Hygiene and Technology, Van, Turkey.

Essential foods of a daily meal have been reported to comprise of numerous kinds of biogenic amines (BAs) at different levels. BAs have a variety of toxicological impacts on human health, and they have been connected to multiple outbreaks of foodborne disease. They also are known to cause cancer based on their ability to react with nitrite salts resulting in the production of a carcinogenic organic compound (i. Read More

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Analysis of Microbiological and Chemical Hazards in Edible Insects Available to Canadian Consumers.

J Food Prot 2021 May 6. Epub 2021 May 6.

Canadian Food Inspection Agency.

Edible insects are a novel food in most countries; their popularity is growing because of their high protein/low fat content, ease of cultivation, and small environmental impact. To our knowledge, this is the first report that addresses both microbiological and chemical hazards in edible insects. Samples were collected from retail stores or purchase through e-commerce. Read More

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Isolation of Bacillus cereus from Soft Soybean Curd, and Kinetic Behavior of the Isolates under Changing Temperature.

J Food Prot 2021 May 6. Epub 2021 May 6.

Sookmyung Women's University Hyochangwon-gil 52 KOREA, REPUBLIC OF Seoul 4310 n/a.

This study isolated Bacillus cereus from soft soybean curds and developed a dynamic model to describe the kinetic behavior of B. cereus isolates during transfer and storage. B. Read More

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Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate.

PLoS Pathog 2021 May 6;17(5):e1009510. Epub 2021 May 6.

Department of Microbiology & Cell Science, University of Florida, Gainesville, Florida, United States of America.

Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric bacteria influence the pathogenesis of neurodegenerative diseases; however, the complexity of the human microbiome hinders our understanding of how individual microbes influence these diseases. Disruption of host protein homeostasis, or proteostasis, affects the onset and progression of these diseases. Read More

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Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo.

PLoS Pathog 2021 May 6;17(5):e1009465. Epub 2021 May 6.

Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, United States of America.

Salmonella Typhimurium is a causative agent of nontyphoidal salmonellosis, for which there is a lack of a clinically approved vaccine in humans. As an intracellular pathogen, Salmonella impacts many cellular pathways. However, the intercellular communication mechanism facilitated by host-derived small extracellular vesicles (EVs), such as exosomes, is an overlooked aspect of the host responses to this infection. Read More

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Assessment of the gut bacterial microbiome and metabolome of girls and women with Rett Syndrome.

PLoS One 2021 6;16(5):e0251231. Epub 2021 May 6.

Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.

Background: Gastrointestinal problems affect the health and quality of life of individuals with Rett syndrome (RTT) and pose a medical hardship for their caregivers. We hypothesized that the variability in the RTT phenotype contributes to the dysbiosis of the gut microbiome and metabolome in RTT, predisposing these individuals to gastrointestinal dysfunction.

Objectives: We characterized the gut bacterial microbiome and metabolome in girls and young women with RTT (n = 44) and unaffected controls (n = 21), and examined the relation between the composition of the microbiome and variations in the RTT phenotype. Read More

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Prevalence and outcomes of co-infection and superinfection with SARS-CoV-2 and other pathogens: A systematic review and meta-analysis.

PLoS One 2021 6;16(5):e0251170. Epub 2021 May 6.

Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.

Introduction: The recovery of other pathogens in patients with SARS-CoV-2 infection has been reported, either at the time of a SARS-CoV-2 infection diagnosis (co-infection) or subsequently (superinfection). However, data on the prevalence, microbiology, and outcomes of co-infection and superinfection are limited. The purpose of this study was to examine the occurrence of co-infections and superinfections and their outcomes among patients with SARS-CoV-2 infection. Read More

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Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection.

PLoS Pathog 2021 May 6;17(5):e1009557. Epub 2021 May 6.

Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

We report a rapid reduction in blink reflexes during in vivo ocular Pseudomonas aeruginosa infection, which is commonly attributed and indicative of functional neuronal damage. Sensory neurons derived in vitro from trigeminal ganglia (TG) were able to directly respond to P. aeruginosa but reacted significantly less to strains of P. Read More

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Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.

MMWR Recomm Rep 2021 May 7;70(2):1-30. Epub 2021 May 7.

Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC.

Botulism is a rare, neurotoxin-mediated, life-threatening disease characterized by flaccid descending paralysis that begins with cranial nerve palsies and might progress to extremity weakness and respiratory failure. Botulinum neurotoxin, which inhibits acetylcholine release at the neuromuscular junction, is produced by the anaerobic, gram-positive bacterium Clostridium botulinum and, rarely, by related species (C. baratii and C. Read More

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Etiology of Infectious Diseases in Acutely Ill Children at a Pediatric Hospital in Finland.

Pediatr Infect Dis J 2021 Jun;40(6):e245-e247

From the Department of Pediatrics and Adolescent Medicine, Oulu University Hospital, Oulu, Finland.

This is a brief report of the etiology of infectious diseases in a pediatric emergency department. Our cohort study of 4647 children demonstrated rhinovirus as the most common etiology in a pediatric emergency department (23%) and intensive care (48%). The population-based incidence of rhinovirus-related visits was 1796/100,000/yr in children <5 years. Read More

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Antimicrobial resistance and antibiotic consumption in a third level pediatric hospital in Mexico City.

J Infect Dev Ctries 2021 Apr 30;15(4):573-578. Epub 2021 Apr 30.

Coordinación de Vigilancia Epidemiológica, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Introduction: The increasing resistance to antibiotics is a public health problem and an imminent therapeutic challenge in hospitals. In this report we aimed to analyze the relationship between antimicrobial resistance and antibiotic consumption in a third-level pediatric hospital.

Methodology: A cross-sectional analysis was conducted using the information from the microbiology and pharmacy databases of the Pediatric Hospital "Doctor Silvestre Frenk Freund", during the period 2015-2018. Read More

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Risk factors of multidrug-resistant bacterial infections among patients admitted in a tertiary care hospital of north India.

J Infect Dev Ctries 2021 Apr 30;15(4):544-551. Epub 2021 Apr 30.

Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Infections with drug-resistant organisms (DRO) have been associated with poor patient outcomes. To tackle this global problem, it is necessary to understand the risk factors that predispose to infections with DRO.

Methodology: This was a prospective observational study conducted over a three-year period at a tertiary-care hospital. Read More

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Detection of blaNDM-1 gene in ESBL producing Escherichia coli and Klebsiella pneumoniae isolated from urine samples.

J Infect Dev Ctries 2021 Apr 30;15(4):516-522. Epub 2021 Apr 30.

Department of Animal Health, University of Agriculture, Peshawar, Pakistan.

Introduction: Enterobacteriaceae such as Escherichia coli and Klebsiella pneumoniae are the most prominent bacterial species resistant to almost all commonly used antibiotics. Carbapenem is one of the last resort drugs for treating such emerging multidrug-resistant bacteria. This study aimed to detect carbapenem-resistant blaNDM-1 gene in ESBL producing E. Read More

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sp. nov., a new member of family isolated from sand fly rearing substrate.

Int J Syst Evol Microbiol 2021 May;71(5)

Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, North Carolina, USA.

A Gram-stain-negative, rod-shaped, non-motile, non-spore-forming, aerobic bacterium, designated type strain SSI9, was isolated from sand fly ( Scopoli; ) rearing substrate and subjected to polyphasic taxonomic analysis. Strain SSI9 contained phosphatidylethanolamine as a major polar lipid, MK-7 as the predominant quinone, and Cω6/Cω, iso-C, iso-C 3-OH and C as the major cellular fatty acids. Phylogenetic analysis based on 16S rRNA gene sequences revealed that SSI9 represents a member of the genus , of the family Sphingobacteriaceae sharing 96. Read More

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