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Dietary intake and associations with myopia in Singapore children.

Ophthalmic Physiol Opt 2021 Dec 3. Epub 2021 Dec 3.

Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

Purpose: To evaluate associations of dietary factors with myopia, spherical equivalent refractive error (SE) and axial length (AL) in children at age 9 from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort.

Methods: We included 467 multi-ethnic children (933 eyes) who participated in the GUSTO prospective birth cohort and were delivered in two major hospitals in Singapore (2009-2010). At the 9-year visit, we assessed the 6-year incidence of myopia (between ages 3 to 9), cycloplegic SE and AL in children without myopia (SE ≤ -0. Read More

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December 2021

REinforcement learning to improve non-adherence for diabetes treatments by Optimising Response and Customising Engagement (REINFORCE): study protocol of a pragmatic randomised trial.

BMJ Open 2021 Dec 3;11(12):e052091. Epub 2021 Dec 3.

Center for Healthcare Delivery Sciences, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Introduction: Achieving optimal diabetes control requires several daily self-management behaviours, especially adherence to medication. Evidence supports the use of text messages to support adherence, but there remains much opportunity to improve their effectiveness. One key limitation is that message content has been generic. Read More

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December 2021

Using nasal povidone-iodine to prevent bloodstream infections and transmission of among haemodialysis patients: a stepped-wedge cluster randomised control trial protocol.

BMJ Open 2021 Dec 3;11(12):e048830. Epub 2021 Dec 3.

Internal Medicine, The University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.

Introduction: Approximately 38% of haemodialysis patients carry in their noses, and carriers have a nearly four-fold increased risk of access-related bloodstream infections (BSIs) compared with non-carriers. Our objective is to determine the clinical efficacy and effectiveness of a novel intervention using nasal povidone-iodine (PVI) to prevent BSIs among patients in haemodialysis units. We will survey patients and conduct qualitative interviews with healthcare workers to identify barriers and facilitators to implementing the intervention. Read More

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December 2021

Intervention targeted at physicians' treatment of musculoskeletal disorders and sickness certification: an interrupted time series analysis.

BMJ Open 2021 Dec 3;11(12):e047018. Epub 2021 Dec 3.

Department of Public Health, University of Helsinki, Helsinki, Finland.

Objective: An intervention was carried out at the occupational healthcare services (OHS) of the City of Helsinki beginning in 2016. We investigated the association between the intervention and employee sick leaves using interrupted time series analysis.

Design: Register-based cohort study with a quasi-experimental study design. Read More

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December 2021

A social skills development training programme to improve adolescents' psychological resilience and emotional intelligence level.

Arch Psychiatr Nurs 2021 Dec 10;35(6):610-616. Epub 2021 Aug 10.

Erciyes University, Faculty of Health Science, Turkey.

Study Objectives: This experimental study was designed using pretest, posttest, follow-up, and control group models to explore the effect of a structured education program on adolescents' psychological resilience and emotional intelligence level.

Method: This study was conducted on 70 students at a high school in Turkey. A total of 36 students were assigned to the intervention group and 34 students to the control group. Read More

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December 2021

Effect of a price display intervention on laboratory test ordering behavior of general practitioners.

BMC Fam Pract 2021 Dec 3;22(1):242. Epub 2021 Dec 3.

Department of Family Medicine, CAPHRI Care and Public Health Research Institute, Maastricht University, PO BOX 616, 6200, MD, Maastricht, The Netherlands.

Background: Redundant use of diagnostic tests in primary care has shown to be a contributor to rising Dutch healthcare costs. A price display in the test ordering system of the electronic health records (EHRs) could potentially be a low-cost and easy to implement intervention to a decrease in test ordering rate in the primary care setting by creating more cost-awareness among general practitioners (GPs). The aim of this study was to assess the effect of a price display for diagnostic laboratory tests in the EHR on laboratory test ordering behavior of GPs in the Westelijke Mijnstreek region in the Netherlands. Read More

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December 2021

A Longitudinal Comparison of Telemedicine Versus In-Person Otolaryngology Clinic Efficiency and Patient Satisfaction During COVID-19.

Ann Otol Rhinol Laryngol 2021 Dec 3:34894211055349. Epub 2021 Dec 3.

Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA.

Objectives: Telemedicine was increasingly adopted in otolaryngology as a result of the COVID-19 pandemic, but how it compares to in-person visits over the longitudinal course of the pandemic has not been characterized. This study compares telemedicine visits to in-person visits on measures of clinical efficiency and patient satisfaction.

Methods: We examined all in-person and telemedicine encounters that occurred during the 13-month period from April 1, 2020 to April 30, 2021 at a pediatric otolaryngology clinic associated with a large tertiary care children's hospital. Read More

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December 2021

Prospective evaluation of the connected biofeedback EMY Kegel trainer in the management of stress urinary incontinence.

J Gynecol Obstet Hum Reprod 2021 Nov 30:102280. Epub 2021 Nov 30.

Department of Gynecology, Strasbourg University Hospital, Strasbourg, France.

Introduction: The aim of this study was to evaluate changes in the quality of life with the connected biofeedback EMY Kegel trainer in patients suffering from stress urinary incontinence. Materiel and methods: This was a prospective, single-center, non-comparative study, which took place between September 2019 and October 2020, in the University Hospitals of Strasbourg. Eligible patients were instructed to use the EMY probe for a minimum of 10 minutes per day for five days per week. Read More

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November 2021

Is Workload Associated with Latissimus Dorsi and Teres Major Tears in Professional Baseball Pitchers? An Analysis of Days of Rest, Innings Pitched and Batters Faced.

J Shoulder Elbow Surg 2021 Nov 30. Epub 2021 Nov 30.

Rothman Orthopaedic Institute, 176 3(rd) Ave., New York, NY 10003, USA. Electronic address:

Background: Latissimus dorsi (LD) and teres major (TM) tears have become increasingly recognized injuries in professional baseball pitchers. The purpose of this study was to determine if workload, as measured by number of days rest between outings, innings pitched, batters faced, and starting pitcher, is associated with increased risk for sustaining a LD/TM tear in professional baseball pitchers.

Methods: All professional baseball pitchers who sustained a LD/TM tear between 2011-2017 were identified using the Major League Baseball (MLB) Health and Injury Tracking System (HITS). Read More

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November 2021

The Utilization of an Electronic Consultation Service During the Coronavirus Disease 2019 Pandemic.

Telemed J E Health 2021 Dec 3. Epub 2021 Dec 3.

Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada.

The coronavirus disease 2019 (COVID-19) pandemic forced many clinicians to rapidly adopt changes in their practice. In this study, we compared patterns of utilization of Ontario eConsult before and after the onset of the COVID-19 pandemic, to assess COVID 19's impact on how eConsult is used. We conducted a longitudinal analysis of registration and utilization data for Ontario eConsult. Read More

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December 2021

Effects of the World Health Organization Safe Childbirth Checklist on Quality of Care and Birth Outcomes in Aceh, Indonesia: A Cluster-Randomized Clinical Trial.

JAMA Netw Open 2021 Dec 1;4(12):e2137168. Epub 2021 Dec 1.

Department of Economics, University of Göttingen, Göttingen, Germany.

Importance: To address major causes of perinatal and maternal mortality, the World Health Organization developed the Safe Childbirth Checklist (SCC), which to our knowledge has been rigorously evaluated only in combination with high-intensity coaching.

Objective: To evaluate the effect of the SCC with medium-intensity coaching on health care workers' performance of essential birth practices.

Design, Setting, And Participants: This cluster randomized clinical trial without blinding included 32 hospitals and community health centers in the province of Aceh, Indonesia (a medium-resource setting) that met the criterion of providing at least basic emergency obstetric and newborn care. Read More

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December 2021

Abdominal aortic aneurysm neck dilatation and sac remodeling in fenestrated compared to standard endovascular aortic repair.

Vascular 2021 Dec 3:17085381211052802. Epub 2021 Dec 3.

Division of Vascular Surgery, 12297New York University Langone Medical Center, New York, NY, USA.

Objective: Contemporary commercially available endovascular devices for the treatment of abdominal aortic aneurysm (AAA) include standard endovascular aortic repair (sEVAR) or fenestrated EVAR (fEVAR) endografts. However, aortic neck dilatation (AND) can occur in nearly 25% of patients following EVAR, resulting in loss of proximal seal with risk of aortic rupture. AND has not been well characterized in fEVAR, and direct comparisons studying AND between fEVAR and sEVAR have not been performed. Read More

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December 2021

High dose supplementation of selenium in left ventricular assist device implant surgery - a double-blinded, randomized controlled, pilot trial.

JPEN J Parenter Enteral Nutr 2021 Dec 3. Epub 2021 Dec 3.

Department of Anesthesiology, Medical Faculty RWTH Aachen, Aachen, Germany.

Background: Systemic inflammation and oxidative stress remain the main cause of complications in heart failure patients receiving a left ventricular assist device (LVAD). Selenoproteins are a cornerstone of antioxidant defense mechanisms for improving inflammatory conditions.

Methods: We conducted a monocentric double-blinded, randomized pilot trial. Read More

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December 2021

Improving Shared Situation Awareness for High-risk Therapies in Hospitalized Children.

Hosp Pediatr 2021 Dec 3. Epub 2021 Dec 3.

Divisions of Hospital Medicine.

Background: High-risk therapies (HRTs), including medications and medical devices, are an important driver of preventable harm in children's hospitals. To facilitate shared situation awareness (SA) and thus targeted harm prevention, we aimed to increase the percentage of electronic health record (EHR) alerts with the correct descriptor of an HRT from 11% to 100% on a high-acuity hospital unit over a 6-month period.

Methods: The interdisciplinary team defined an HRT as a medication or device with a significant risk for harm that required heightened awareness. Read More

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December 2021

Relevance of Frequency-Domain Analyses to Relate Shoe Cushioning, Ground Impact Forces and Running Injury Risk: A Secondary Analysis of a Randomized Trial With 800+ Recreational Runners.

Front Sports Act Living 2021 11;3:744658. Epub 2021 Nov 11.

ALAN-Maladies Rares Luxembourg, Luxembourg, Luxembourg.

Cushioning systems in running shoes are used assuming that ground impact forces relate to injury risk and that cushioning materials reduce these impact forces. In our recent trial, the more cushioned shoe version was associated with lower injury risk. However, vertical impact peak force was higher in participants with the Soft shoe version. Read More

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November 2021

Factors for Visual Acuity Improvement After Anti-VEGF Treatment of Wet Age-Related Macular Degeneration in China: 12 Months Follow up.

Front Med (Lausanne) 2021 11;8:735318. Epub 2021 Nov 11.

Department of Ophthalmology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, China.

To evaluate the treatment solutions and effectiveness of intravitreal ranibizumab (RBZ) or conbercept in patients with wet age-related macular degeneration (wAMD) in a real-life setting in China. The medical records of 368 patients with wAMD who started RBZ or conbercept treatment between 1 May 2014 and 30 April 2018 were evaluated. All patients were defined on fundus angiography at baseline to determine the subtype of AMD (PCV or CNV). Read More

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November 2021

Feasibility and preliminary efficacy of acupuncture for angina in an underserved diverse population.

Acupunct Med 2021 Dec 2:9645284211055754. Epub 2021 Dec 2.

Department of Human Development Nursing Science, College of Nursing, University of Illinois Chicago, Chicago, IL, USA.

Purpose: Stable angina is ischemic chest pain on exertion or with emotional stress. Despite guideline-directed therapy, up to 30% of patients have suboptimal pain relief. The aims of this study were to: (1) determine the feasibility and acceptability of a randomized controlled trial (RCT) of acupuncture; and (2) evaluate preliminary efficacy of acupuncture with respect to reduction of pain and increased functional status and health-related quality of life (HRQoL). Read More

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December 2021

Caregiver perceived financial strain during pediatric cancer treatment: Longitudinal predictors and outcomes.

Health Psychol 2021 Dec 2. Epub 2021 Dec 2.

Department of Psychology.

Objective: Previous work has examined family income and material hardship in pediatric cancer. However, few studies have focused on perceived financial strain (PFS), or the extent to which caregivers perceive financial stress and worry related to their child's cancer. The current study addresses this gap by a) describing the trajectory of perceived financial strain over the first year of pediatric cancer treatment; b) examining sociodemographic predictors of that trajectory; and c) examining associations between PFS and caregiver and child psychological adjustment. Read More

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December 2021

Leaf trait modification in European beech trees in response to climatic and edaphic drought.

Plant Biol (Stuttg) 2021 Dec 1. Epub 2021 Dec 1.

Plant Ecology, Albrecht von Haller Institute for Plant Sciences, University of Göttingen, Göttingen, Germany.

Leaf morphological and physiological traits control the carbon and water relations of mature trees and are determinants of drought tolerance, but it is not well understood how they are modified in response to water deficits. We analysed five sun-canopy leaf traits (mean leaf size (LS), specific leaf area (SLA), Huber value (HV), water potential at turgor loss point (Ψ ) and foliar carbon isotope signature (δ C)) in European beech (Fagus sylvatica L.) across three precipitation gradients sampled in moist (2010), dry (2019) and very dry (2018) summers, and tested their response to short-term water deficits (climatic water balance (CWB) preceding sample collection) and long-term water availability (mean annual precipitation (MAP), plant-available soil water capacity (AWC) and neighbourhood competition). Read More

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December 2021

Preoperative and Postoperative Opioid Prescription Rates in the Total Hip Replacement Surgical Patient.

Orthop Nurs 2021 Nov-Dec 01;40(6):366-374

Shawna Schmidt, BSN, RN, SRNA, Nurse Anesthesia Student, Duke University School of Nursing, Durham, NC.

The United States is facing an opioid epidemic that has only worsened with the COVID-19 pandemic. There is little evidence regarding patterns of opioid use among patients with total hip replacement (THR). Although the Centers for Disease Control and Prevention has put forward guidelines for prescribing opioids, it does not include guidance specifically for THR patients suffering from presurgical and postsurgical pain. Read More

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December 2021

STEPP IN: A Multicenter Quality Improvement Collaborative Standardizing Postoperative Handoffs.

Pediatrics 2021 Dec;148(6)

Division of Neonatology, Department of Pediatrics, School of Medicine, University of Missouri-Kansas City and Children's Mercy Kansas City, Missouri.

Objective: To reduce care failures by 30% through implementation of standardized communication processes for postoperative handoff in NICU patients undergoing surgery over 12 months and sustained over 6 months.

Methods: Nineteen Children's Hospitals Neonatal Consortium centers collaborated in a quality improvement initiative to reduce postoperative care failures in a surgical neonatal setting by decreasing respiratory care failures and all other communication failures. Evidence-based clinical practice recommendations and a collaborative framework supported local teams' implementation of standardized postoperative handoff communication. Read More

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December 2021

Household-level consumption data can be redistributed for individual-level Optifood diet modeling: analysis from four countries.

Ann N Y Acad Sci 2021 Nov 30. Epub 2021 Nov 30.

Department of Population Health, London School of Hygiene and Tropical Medicine, London, UK.

A barrier to using Optifood linear programming (LP), which identifies nutrient gaps and supports population-specific food-based recommendation (FBR) development, is the requirement for dietary intake data. We investigated whether Household Consumption and Expenditure Surveys (HCESs) could be used instead of individual-level 24-h recalls (24HRs). The 24HR data from 12- to 23-month-old breastfeeding children in rural Kenya, Uganda, Guatemala, and Bangladesh were paired with HCES food consumption data from similar areas (n = 8) and time periods. Read More

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November 2021

Infant feeding, growth monitoring and the double burden of malnutrition among children aged 6 months and their mothers in KwaZulu-Natal, South Africa.

Matern Child Nutr 2021 Nov 29:e13288. Epub 2021 Nov 29.

School of Nursing and Public Health, Centre for Rural Health, University of KwaZulu-Natal, Durban, South Africa.

South Africa has a documented high prevalence of stunting and increasing obesity in children as well as obesity in adults. The double burden of malnutrition, which can be on an individual-, household- or population level, has implications for both health and the economic development of a community and country. This paper describes a large-scale survey (N = 774) of infant feeding, growth monitoring and anthropometry among mother and child pairs aged 6 months of age in KwaZulu-Natal (KZN), South Africa, conducted between January and August 2017. Read More

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November 2021

MicroPulse® transscleral laser therapy in the management of glaucoma patients.

Arch Soc Esp Oftalmol (Engl Ed) 2021 Dec 21;96(12):640-648. Epub 2021 May 21.

Departamento de Oftalmología, Ain Shams University Hospitals, Ain Shams University, El Cairo, Egypt.

Purpose: To evaluate the efficacy and safety of MicroPulse® transscleral laser therapy (TLT) in the management of glaucoma patients.

Methods: A prospective, interventional, non-comparative case series was conducted in the department of ophthalmology, Ain Shams University Hospital on 61 eyes of 46 patients with various glaucoma types and of severity, ranging from mild to severe. In addition to best-corrected visual acuity (BCVA), intraocular pressure (IOP) and the number of glaucoma medications were recorded before and after treatment, along with the postoperative need for systemic carbonic anhydrase inhibitors (CAI), success rates, number of treatment sessions and postoperative complications. Read More

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December 2021

Cochlear implant in immune mediated inner ear diseases: Impedance variations and clinical outcomes.

Cochlear Implants Int 2021 Nov 30:1-10. Epub 2021 Nov 30.

Department of Sense Organs, "Sapienza" University of Rome, Rome, Italy.

Objective: Immune-mediated inner ear disease (IMIED) might cause severe/profound hearing loss and these patients are considered ideal candidates to cochlear implant (CI) surgery. The aim of the study was to evaluate impedance changes over time.

Method: The Study Group (SG) was composed of CI IMIED patients (31 ears) and a Control Group (CG) of CI patients with hearing loss not related to their immune system (31 ears). Read More

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November 2021

Favorable Response to "Memantine" in a Child with GRIN2B Epileptic Encephalopathy.

Neuropediatrics 2021 Nov 29. Epub 2021 Nov 29.

Division of Paediatric Neurology, Department of Neurology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu.

is a gene encoding subunit under the family of N-methyl D-aspartate (NMDA) receptors, which is responsible for neurogenesis and cognitive processes. The role of NMDA receptor antagonists like memantine is being explored for therapies in drug-resistant epilepsies. Here, we present a case of a 20-month-old boy who presented with refractory epileptic spasms. Read More

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November 2021

The impact of cochlear implantation on speech and language outcomes in children with asymmetric sensorineural hearing loss.

Int J Pediatr Otorhinolaryngol 2021 Nov 17;152:110979. Epub 2021 Nov 17.

Department of Pediatric Otolaryngology, Nationwide Children's Hospital, Columbus, OH, USA. Electronic address:

Introduction: Cochlear implantation (CI) is considered in children with asymmetric sensorineural hearing loss (ASHL), or severe to profound sensorineural hearing loss in one ear, and better hearing contralaterally. The benefits of a CI in these children are not well established. This study investigated the impact of unilateral CI on speech and language outcomes in pediatric patients with ASHL. Read More

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November 2021

Evaluating spatio-temporal soil erosion dynamics in the Winam Gulf catchment, Kenya for enhanced decision making in the land-lake interface.

Sci Total Environ 2021 Nov 26:151975. Epub 2021 Nov 26.

Inorganic Geochemistry, British Geological Survey, Nottingham NG12 5GG, UK.

Soil erosion accelerated by poor agricultural practices, land degradation, deprived infrastructure development and other anthropogenic activities has important implications for nutrient cycling, land and lake productivity, loss of livelihoods and ecosystem services, as well as socioeconomic disruption. Enhanced knowledge of dynamic factors influencing soil erosion is critical for policymakers engaged in land use decision-making. This study presents the first spatio-temporal assessment of soil erosion risk modelling in the Winam Gulf, Kenya using the Revised Universal Soil Loss Equation (RUSLE) within a geospatial framework at a monthly resolution between January 2017 and June 2020. Read More

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November 2021

The longitudinal buffering effects of resilience on alcohol use outcomes.

Psychol Trauma 2021 Nov 29. Epub 2021 Nov 29.

Virginia Institute for Psychiatric and Behavioral Genetics.

Objective: Traumatic events (TE) are a risk factor for alcohol use disorder (AUD). Resilience may be protective of the effects of TE exposure, but few studies have longitudinally tested the buffering hypothesis. Thus, the present study aimed to fill this gap. Read More

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November 2021

Major trauma with only dynamic criteria: is the routine use of whole-body CT as a first level examination justified?

Radiol Med 2021 Nov 29. Epub 2021 Nov 29.

Radiology Unit, Maggiore Hospital "Carlo Alberto Pizzardi", 40133, Bologna, Italy.

Purpose: Risks and benefits of systematic use of whole-body CT (WBCT) in patients with major trauma when no injury is clinically suspected is still subject of controversy. WBCT allows early identification of potentially evolving lesions, but exposes patients to the risk of high radiation dose and iodine contrast agent. The study aimed to assess if WBCT could be avoided in trauma patients with negative clinical examination. Read More

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November 2021