Biol Psychiatry Cogn Neurosci Neuroimaging 2021 Jul 22. Epub 2021 Jul 22.
Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, Georgia, United States; Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States; Department of Psychiatry, Yale University, School of Medicine, New Haven, Connecticut, United States; Department of Psychology, Computer Science, Neuroscience Institute, and Physics, Georgia State University, Atlanta, Georgia, United States.
Background: Depressive episodes (DEP) characterized by abnormalities in cognitive functions and mood is a leading cause of disability. Electroconvulsive therapy (ECT), which involves a brief electrical stimulation of the anesthesia brain, is one of the most effective treatments used in patients with DEP due to its rapid efficacy.
Methods: In this work, we investigated how dynamic brain functional connectivity responds to ECT and whether the dynamic responses are associated with treatment outcomes and side effects in patients. Read More