150 results match your criteria autogenous osteochondral


Arthroscopic evaluation after osteochondral autogenous transfer with osteotomy of medial malleolus for osteochondral lesion of the talar dome.

Foot Ankle Surg 2021 Feb 4. Epub 2021 Feb 4.

Department of Orthopedic Surgery, Kyoto Katsura Hospital, Japan.

Background: The purpose of this study was to investigate the second-look arthroscopic evaluation after osteochondral autogenous transfer (OAT) for osteochondral lesion of the talar dome (OLT) with the criteria of the International Cartilage Repair Society (ICRS).

Methods: Ten patients (twelve ankles) with OLT underwent OAT with osteotomy of the medial malleolus. Clinical outcomes were evaluated using the American Orthopedic Foot & Ankle Society (AOFAS) ankle-hindfoot scale. Read More

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February 2021

A Novel Technique to Treat Hallux Rigidus in Athletic Patients With Central Osteochondral Defects: Preliminary Report on 12 Cases.

J Foot Ankle Surg 2020 Dec 31. Epub 2020 Dec 31.

Podiatric Physician and Surgeon, Reconstructive Orthopedics, Sewell, NJ.

Osteochondral defects, often caused by traumatic injuries, are focal areas of articular damage resulting in joint pain and stiffness ultimately leading to degenerative joint disease. This has not been well studied in the first metatarsal head, but is an often encountered problem in the active population in other joints. In this study, we prospectively evaluated the results of 12 patients who received autogenous bone grafting for repair of osteochondral defects of the first metatarsal head. Read More

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December 2020

Contamination and Decontamination of Autologous Bone in the Operating Room: A Systematic Review.

J Orthop Trauma 2021 02;35(2):65-70

Department of Orthopedic Surgery, Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Objective: To perform a systematic review of the literature to determine the rate of contamination of autologous bone fragments inadvertently dropped on the operating room floor, the microbial profile (contaminating organism), and the outcome of intraoperative decontamination techniques in terms of effectiveness and cellular toxicity.

Data Sources: PubMed, Medline, and Embase were searched for English literature published from 1990 through 2020 using terms such as "bone graft contamination," "dropped osteoarticular fragments," "autogenous bone decontamination," and similar interchangeable words.

Study Selection: Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. Read More

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February 2021

[Lateral ligament reconstruction with autogenous partial peroneus longus tendon for chronic lateral ankle instability].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Sep;34(9):1114-1119

Department of Hand and Foot Surgery, Affiliated Hospital of Qingdao University, Qingdao Shandong, 266000, P.R.China.

Objective: To assess the effectiveness of lateral ligament reconstruction with autogenous partial peroneus longus tendon for chronic lateral ankle instability.

Methods: Between September 2014 and November 2018, 32 patients (32 sides) with chronic lateral ankle instability were treated with lateral ankle ligament reconstruction by using autogenous anterior half of the peroneus longus tendon. There were 25 males and 7 females, with an average age of 28. Read More

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September 2020

Autogenous Osteochondral Grafting for Treatment of Knee Osteochondritis Dissecans: A Case Series Study.

Arch Bone Jt Surg 2020 May;8(3):426-431

Akhtar Orthopedic Training and Research Hospital, Shahid Beheshti University of medical Sciences, Tehran, Iran.

Background: Although some surgical techniques have been described for the operative treatment of unstable Osteochondritis dissecans (OCD) of the knee, outcomes are variable and are not satisfying totally. The aim of the present study is to evaluate the outcomes of autogenous osteochondral grafting for OCD of the knee.

Methods: In a case series study, from June 2014 to July 2015, 16 patients with stage II-IV OCD (International Cartilage Repair Society (ICRS)) of the femoral condyle were investigated. Read More

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Comparison of meniscal allograft transplantation techniques using a preclinical canine model.

J Orthop Res 2021 01 31;39(1):154-164. Epub 2020 Mar 31.

Department of Orthopaedic Surgery, Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

Meniscal allograft transplantation (MAT) can be a safe, effective treatment for meniscal deficiency resulting in knee dysfunction, leading to osteoarthritis (OA) without proper treatment with 5-year functional success rates (75%-90%). While different grafts and techniques have generally proven safe and effective, complications include shrinkage, extrusion, progression of joint pathology, and failure. The objective of this study was to assess the functional outcomes after MAT using three different clinically-relevant methods in a preclinical canine model. Read More

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January 2021

[The clinical effect of autologous osteochondral transplantation via biplanar osteotomy for osteochondral lesions of the talus combined with subchondral cysts].

Zhonghua Wai Ke Za Zhi 2020 Mar;58(3):220-224

Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

To examine the clinical effect of autologous osteochondral transplantation via biplanar osteotomy for osteochondral lesions of the talus combined with subchondral cysts. A retrospective analysis of 25 patients who underwent autogenous osteochondral transplantation via biplanar osteotomy for treatment of talus osteochondral injury combined with subchondral cysts at Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University from December 2015 to December 2018 were conducted.There were 21 males and 4 females, aged 35. Read More

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Prospective Assessment of Outcomes After Primary Unipolar, Multisurface, and Bipolar Osteochondral Allograft Transplantations in the Knee: A Comparison of 2 Preservation Methods.

Am J Sports Med 2020 05 5;48(6):1356-1364. Epub 2020 Mar 5.

Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA.

Background: Articular cartilage lesions in the knee remain a challenging clinical problem.

Hypothesis: A novel graft preservation method combined with surgical technique and patient management improvements would lead to consistently successful outcomes after osteochondral allograft (OCA) transplantation.

Study Design: Cohort study; Level of evidence, 3. Read More

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Editorial Commentary: Bone Marrow Aspirate Biologics for Osteochondral Allografts-Because We Can or Because We Should?

Authors:
James L Cook

Arthroscopy 2019 08;35(8):2445-2447

University of Missouri.

Orthobiologics are all the rage these days, and one of the hottest areas of study involves the use of autogenous bone marrow-derived biologics for preimplantation treatment of osteochondral allografts. Three recent Level III cohort studies based on shifts in practice have reported early imaging-based assessments of osteochondral allograft bone integration in the knee. Each study had unique, major limitations, and each reported disparate results. Read More

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Effect of Autogenous Bone Marrow Aspirate Treatment on Magnetic Resonance Imaging Integration of Osteochondral Allografts in the Knee: A Matched Comparative Imaging Analysis.

Arthroscopy 2019 08;35(8):2436-2444

Hospital for Special Surgery, New York, New York, U.S.A.. Electronic address:

Purpose: To accurately evaluate the effects of bone marrow aspirate (BMA) augmentation on osteochondral allograft (OCA) integration on early postoperative magnetic resonance imaging (MRI) using the comprehensive Osteochondral Allograft MRI Scoring System (OCAMRISS).

Methods: This imaging study compared patients who underwent OCA transplantation with and without BMA augmentation for the treatment of focal osteochondral defects in the knee performed by a single surgeon between July 2013 and July 2017. Patients were excluded if they underwent implantation of premade plugs, had an overlapping OCA configuration ("snowman" technique), or did not undergo MRI at 6 months postoperatively. Read More

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[Comparison of curative effect between osteochondral mosaic transplantation and micro-fracture in the treatment of knee joint articular cartilage injury].

Zhongguo Gu Shang 2019 Jun;32(6):539-543

Department of Joint Surgery and Sports Medicine, the 113th Hospital of People Liberation Army, Ningbo 315040, Zhejiang, China.

Objective: To compare the clinical outcomes of microfracture and autogenous osteochondral mosaic transplantation in the treatment of knee joint cartilage injury.

Methods: A retrospective analysis of 71 patients with articular cartilage defects on the femoral condyles who were by autogenous osteochondral mosaic transplantation or microfracture from February 2011 to February 2016, and these patients were followed up for at least 2 years. According to the sugical procedures, the patients were divided into two groups. Read More

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[Follow-up study on autogenous osteochondral transplantation for cartilage defect of knee joint].

Zhongguo Gu Shang 2019 Apr;32(4):346-349

Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou 730030, Gansu, China;

Objective: To evaluate clinical effect of autologous osteochondral transplantation in treating localized knee cartilage defects.

Methods: Fifteen patients with knee cartilage defects were treated by autologous osteochondral transplantation from January 2007 to January 2008, including 8 females and 7 males, aged from 23 to 45 years old. Preoperative and postoperative KSS score at 10 years were compared. Read More

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Thermosensitive Hydrogels as Scaffolds for Cartilage Tissue Engineering.

Biomacromolecules 2019 04 20;20(4):1478-1492. Epub 2019 Mar 20.

Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences , 5625 Renmin Street , Changchun 130022 , P. R. China.

Articular cartilage defects, caused by trauma, osteoarthritis, or other diseases, always lead to severe joint pain and joint dysfunction. Without access to progenitor cells and the supply of blood and nutrients, the impaired articular cartilage would be short of the capability to self-repair. Although the present clinical treatments, including autogenous and allograft osteochondral transplantation, microfracture technique, and so forth, have shown some efficacies, their drawbacks, such as donor insufficiency and poor-integration with adjacent tissue, limit the satisfactory repair of articular cartilage defects and cause unsatisfied prognosis. Read More

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[Autogenous iliac bone graft for osteochondral lesions of the talus with subchondral cyst].

Authors:
Min Wei Yang Liu

Zhongguo Gu Shang 2019 Jan;32(1):43-47

Department of Orthopaedics, Chinese PLA General Hospital, Beijing 100853, China.

Objective: To evaluate clinical effect of autogenous iliac bone graft in treating osteochondral lesion of the talus with subchondral cyst.

Methods: Twenty-two osteochondral lesion of talus patients with subchondral cyst were collected from January 2011 to December 2014, including 18 males and 4 females aged from 34 to 58 years old with an average of (46.4± 6. Read More

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January 2019

Surgical outcomes of extracorporeal irradiation and re-implantation in extremities for high grade osteosarcoma: A retrospective cohort study and a systematic review of the literature.

J Bone Oncol 2019 Feb 10;14:100210. Epub 2018 Dec 10.

Orthopedic Laboratory and Research Network (OLARN), Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Purpose: To assess the failure rate and mode failure of high-grade osteosarcoma patients who received extracorporeal irradiation and re-implantation (ECIR) in extremities.

Patients And Methods: For the cohort study, patients who had received ECIR at a single institution between January 1996 and December 2014 were retrospectively evaluated. Characteristics of failure and time to failure were recorded and analyzed. Read More

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February 2019

Bone Marrow Aspirate Concentrate Does Not Improve Osseous Integration of Osteochondral Allografts for the Treatment of Chondral Defects in the Knee at 6 and 12 Months: A Comparative Magnetic Resonance Imaging Analysis.

Am J Sports Med 2019 02 13;47(2):339-346. Epub 2018 Dec 13.

Sports Medicine Service, Hospital for Special Surgery, New York, New York, USA.

Background: Poor osseous integration after fresh osteochondral allograft transplantation (OCA) may be associated with graft subsidence and subchondral bone collapse after implantation. The augmentation of OCA with bone marrow aspirate concentrate (BMAC) has been hypothesized to improve osseous incorporation of the implanted allograft.

Purpose: To evaluate the effect of autogenous BMAC treatment on osseous integration at the graft-host bony interface after OCA. Read More

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February 2019

Unstable Osteochondritis Dissecans of the Glenoid Fixed with Autogenous Osteochondral Plugs in a College Baseball Player: A Case Report.

JBJS Case Connect 2018 Oct-Dec;8(4):e99

Miraidaira Orthopaedic Clinic, Tsukubamirai, Japan.

Case: A 19-year-old college baseball outfielder presented with a 3-month history of right shoulder pain. Radiographs, computed tomography, and magnetic resonance imaging showed a large osteochondral defect at the posterosuperior aspect of the glenoid. Arthroscopic evaluation identified an unstable fragment that was partially attached. Read More

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November 2019

Scaffold-free cartilage cell sheet combined with bone-phase BMSCs-scaffold regenerate osteochondral construct in mini-pig model.

Am J Transl Res 2018 15;10(10):2997-3010. Epub 2018 Oct 15.

Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at San Antonio TX, USA.

Tissue-engineered condyles provide a promising approach for end-stage osteoarthritis to reconstruct normal physiological structure and function of the temporomandibular joint (TMJ). However, lack of successful biological condyles in large animals restricts clinical translation. Scaffold-free cartilage cell sheets do not contain any polymeric material which potentially risks local nonspecific inflammatory reactions. Read More

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October 2018

Management of the Posttraumatic Coronoid-Deficient Elbow.

J Hand Surg Am 2019 May 2;44(5):400-410. Epub 2018 Oct 2.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN. Electronic address:

Posttraumatic coronoid deficiency is one of the most challenging scenarios even for the most experienced elbow surgeon. Surgical options can be grouped into soft tissue reconstructions, autogenous corticocancellous bone graft reconstructions, osteochondral reconstructions, and prosthetic replacement. However, the literature is inconclusive with limited cases, short follow-up, and no conclusive clinical comparative studies of these techniques. Read More

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Bony Reconstruction of the Anterior Glenoid Rim.

J Am Acad Orthop Surg 2018 May;26(10):e207-e218

From the Mayo Clinic, Rochester, MN (Dr. Willemot and Dr. Elhassan) and AZ Monica and University Hospital of Antwerp, Antwerp, Belgium (Dr. Verborgt).

Recurrent anterior shoulder instability is associated with glenohumeral bone loss. Glenoid deficiency compromises the concavity-compression mechanism. Medial Hill-Sachs lesions can result in an off-track humeral position. Read More

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Comparison of Techniques for Preimplantation Treatment of Osteochondral Allograft Bone.

J Knee Surg 2019 Jan 7;32(1):97-104. Epub 2018 Mar 7.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

Articular defects are a major problem with few effective treatment options. Osteochondral allograft (OCA) transplantation can be an effective treatment; however, lack of OCA bone integration can cause failure. This controlled laboratory study was designed to compare clinically applicable methods for marrow element removal and enhanced delivery of bone marrow aspirate concentrate (BMC) to OCA bone. Read More

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January 2019

Scaffold-Based Temporomandibular Joint Tissue Regeneration in Experimental Animal Models: A Systematic Review.

Tissue Eng Part B Rev 2018 08 8;24(4):300-316. Epub 2018 Mar 8.

1 Department of Clinical Dentistry, Center for Clinical Dental Research, University of Bergen , Bergen, Norway .

Reconstruction of degenerated temporomandibular joint (TMJ) structures remains a clinical challenge. Tissue engineering (TE) is a promising alternative to current treatment options, where the TMJ is either left without functional components, or replaced with autogenous, allogeneic, or synthetic grafts. The objective of this systematic review was to answer the focused question: in experimental animal models, does the implantation of biomaterial scaffolds loaded with cells and/or growth factors (GFs) enhance regeneration of the discal or osteochondral TMJ tissues, compared with scaffolds alone, without cells, or GFs? Following PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analysis) guidelines, electronic databases were searched for relevant controlled preclinical in vivo studies. Read More

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Management of Osteochondral Lesions of the Talar Dome.

Open Orthop J 2017 31;11:743-761. Epub 2017 Jul 31.

Department of Orthopaedics and Rehabilitation, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, IA, 52242.

Osteochondral lesion of the talus (OLT) is a common condition associated with ankle injury that brings challenges in the diagnosis and treatment. Symptoms related to this condition are nonspecific including pain, swelling, stiffness, and mechanical symptoms of locking and catching. While the natural history of the OLTs is not well understood, surgical treatment is often required especially in chronic cases and acute cases with displaced articular fragments. Read More

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Effects of Autogenous Bone Marrow Aspirate Concentrate on Radiographic Integration of Femoral Condylar Osteochondral Allografts.

Am J Sports Med 2017 Oct 24;45(12):2797-2803. Epub 2017 Jul 24.

Department of Orthopaedic Surgery, University of Missouri School of Medicine, Columbia, Missouri, USA.

Background: Transplantation of fresh osteochondral allografts (OCAs) is an attractive treatment option for symptomatic articular cartilage lesions in young, healthy patients. Because the lack of OCA bone integration can be a cause of treatment failure, methods for speeding and enhancing OCA bone integration to mitigate this potential complication are highly desirable.

Purpose: To determine if autogenous bone marrow aspirate concentrate (BMC) treatment of large femoral condylar OCAs would be associated with superior radiographic OCA bone integration compared with nontreated allografts during the critical first 6 months after surgery. Read More

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October 2017

A Novel Rhinoplasty Sculpture Technique Using Ancient Chinese Architectural Technology.

J Craniofac Surg 2017 Sep;28(6):1437-1441

Department of Plastic and Reconstructive Surgery, The Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.

Rhinoplasty is one of the most delicate procedures in plastic and reconstructive surgery. Precision in every millimeter is vital in ensuring a better quality of surgical outcome. Many methods have been developed to fulfill this requirement. Read More

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September 2017

Bone Marrow Aspirate Concentrate versus Platelet Rich Plasma to Enhance Osseous Integration Potential for Osteochondral Allografts.

J Knee Surg 2018 Apr 24;31(4):314-320. Epub 2017 Jun 24.

Department of Orthopaedic Surgery/Thompson Laboratory for Regenerative Orthopaedics, Missouri Orthopaedic Institute, University of Missouri, Columbia, Missouri.

Fresh osteochondral allograft (OCA) transplantation is an attractive treatment option for symptomatic articular cartilage lesions in young, healthy patients. Since a lack of OCA bone integration can be a cause of treatment failure, methods for speeding and enhancing OCA bone integration to mitigate this potential complication are highly desirable. This study sought to determine and compare the potential of bone marrow aspirate concentrate (BMC) and leukoreduced platelet rich plasma (PRP) to repopulate the osseous portion of an OCA with cells and deliver osteogenic proteins. Read More

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Plate Fixation Technique for Reducing Osteoarticular Allograft Fracture: A Preliminary Report.

J Med Assoc Thai 2016 Oct;99(10):1110-8

Background: Osteoarticular allograft is now commonly used as a reconstructive biomaterial to replace bone defect following removal of aggressive bone tumors and for revision of failed arthroplasty. Good long-term clinical result of allograft replacement has been demonstrated. However, the rate of complications is high, including deep infection, allograft fracture, delayed union or non-union, and joint instability. Read More

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October 2016

Osteochondral Autograft from the Ipsilateral Femoral Head by Surgical Dislocation for Treatment of Femoral Head Fracture Dislocation: A Case Report.

Yonsei Med J 2016 Nov;57(6):1527-30

Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.

As anatomical reduction of the articular surface of femoral head fractures and restoration of damaged cartilage are essential for good long-term results, many treatment options have been suggested, including fixation of the fracture using various surgical exposures and implants, as well as arthroscopic irrigation and debridement, bone marrow stimulating techniques, osteochondral allograft, autograft, and autogenous chondrocyte implantation. We report a case of osteochondral autograft harvested from its own femoral articular surface through surgical hip dislocation. The osteochondral graft was harvested from the inferior non-weight-bearing articular surface and grafted to the osteochondral defect. Read More

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November 2016

Treatment of unstable osteochondritis dissecans in adults with autogenous osteochondral grafts (Mosaicplasty): long-term results.

Joints 2015 Oct-Dec;3(4):173-8. Epub 2016 Jan 31.

Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.

Purpose: the unstable osteochondritis dissecans (OCD-type II and III according to the ICRS classification) of the knee largher than > 2.5 cm(2) in adults are uncommon lesions and there is no consensus on how to treat them. Medium-term studies have reported good results using autogenous osteochondral plugs (mosaicplasty). Read More

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February 2016