J Rheumatol 2020 Dec 15. Epub 2020 Dec 15.
Division of Rheumatology and Intensive Care Unit, Department of Medicine; Department of Laboratory Medicine; Department of Sports Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Corgenix Inc., Broomfield, CO, USA; Okayama University Graduate School of Medicine, Okayama, Japan; Third Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary; Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel. Address correspondence to: Prof Dr Zoltán Szekanecz, MD, PhD, University of Debrecen Faculty of Medicine, Department of Rheumatology, Nagyerdei str 98, Debrecen, 4032, Hungary. Email:
Objective: Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) have been associated with cardiovascular (CV) disease. The treatment of arthritis by tumour necrosis factor α (TNF- α) inhibitors may decrease the serum concentrations of vascular biomarkers. We determined circulating levels of oxidized LDL (oxLDL)/β2 glycoprotein I (β2GPI) complexes, antibodies to 60 kDa heat shock protein (anti-Hsp60), soluble urokinase plasminogen activator receptor (suPAR) and Brain type natriuretic peptide (BNP) fragment in sera of RA and AS patients undergoing anti-TNF treatment. Read More