2,363 results match your criteria atherogenesis complete


Mechanics of the cell: Interaction mechanisms and mechanobiological models.

Curr Top Membr 2020 2;86:143-184. Epub 2020 Oct 2.

Department of Bioengineering, University of Texas at Arlington, Arlington, TX, United States. Electronic address:

The importance of cell mechanics has long been recognized for the cell development and function. Biomechanics plays an important role in cell metabolism, regulation of mechanotransduction pathways and also modulation of nuclear response. The mechanical properties of the cell are likely determined by, among many others, the cytoskeleton elasticity, membrane tension and cell-substrate adhesion. Read More

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October 2020

[Comparative analysis of safety of carotid endarterectomy performed in acutest and acute periods of ischaemic stroke].

Angiol Sosud Khir 2021 ;27(1):97-106

Chair of Cardiovascular and Endovascular Surgery, Kazan State Medical University of the RF Ministry of Public Health, Kazan, Russia.

Surgical revascularization of the carotid basin in the acutest period of ischaemic stroke, i.e., within 72 hours, will make it possible to prevent the development of recurrent stroke by removing an embologenically dangerous atherosclerotic plaque of the symptomatic carotid artery and to improve cerebral blood supply, having eliminated haemodynamic stenosis of the carotid artery. Read More

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Coronary endarterectomy in coronary artery disease: Factors affecting graft patency and survival.

Asian Cardiovasc Thorac Ann 2021 Apr 6:2184923211006851. Epub 2021 Apr 6.

Division of Cardiothoracic Surgery, Department of Surgery, 13621Prince of Wales Hospital, The Chinese University of Hong Kong, New Territories, Hong Kong.

Background: Coronary endarterectomy aims to improve completeness of revascularization in patients with occluded coronary vessels. The benefits of coronary endarterectomy remain uncertain. The aim of this study was to evaluate short-term surgical outcomes and factors affecting graft patency post-coronary endarterectomy. Read More

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Changes in the profile of circulating HDL subfractions in severe obese adolescents following a weight reduction program.

Nutr Metab Cardiovasc Dis 2021 Feb 10. Epub 2021 Feb 10.

Institute of Bioengineering and Department of Applied Biology-Nutrition, University Miguel Hernandez, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain. Electronic address:

Background And Aims: Epidemiological studies show that obese adolescents are candidates to suffer cardiovascular pathologies in adulthood. In order to detect subfractions with a diagnostic value for future cardiovascular disorders, we analyzed the complete lipoprotein profile of severely obese adolescents.

Methods And Results: Twenty-eight obese adolescents free from comorbidities were admitted into a weight reduction program. Read More

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February 2021

Genetic Deletion of Trace-Amine Associated Receptor 9 (TAAR9) in Rats Leads to Decreased Blood Cholesterol Levels.

Int J Mol Sci 2021 Mar 14;22(6). Epub 2021 Mar 14.

Institute of Translational Biomedicine, Saint Petersburg State University, Universitetskaya nab., 7-9, 199034 Saint Petersburg, Russia.

In the last two decades, interest has grown significantly in the investigation of the role of trace amines and their receptors in mammalian physiology and pathology. Trace amine-associated receptor 9 (TAAR9) is one of the least studied members of this receptor family with unidentified endogenous ligands and an unknown role in the central nervous system and periphery. In this study, we generated two new TAAR9 knockout (TAAR9-KO) rat strains by CRISPR-Cas9 technology as in vivo models to evaluate the role of TAAR9 in mammalian physiology. Read More

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Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO-1 and NF-kB Pathways.

Curr Med Chem 2021 Mar 29. Epub 2021 Mar 29.

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres, n 31, Messina 98166. Italy.

Background: Vascular remodeling processes induced by acute and chronic injuries are characterized by inflammation and oxidative stress. In arteriosclerosis, atherosclerosis and restenosis, the progression of neointimal hyperplasia is a key event of vascular damage.

Objective: Our study was aimed to investigate the inflammation and oxidative stress development during vascular impairment and the potential efficacy of treatment of new micro composite N-palmitoylethanolamine /Rutin at a ratio of 1:1 (PEA/RUT). Read More

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Spinal infarcts.

Authors:
D Leys J-P Pruvo

Rev Neurol (Paris) 2021 Mar 25. Epub 2021 Mar 25.

Inserm U 1172, CHU de Lille, University of Lille, Lille, France; Department of Neuroradiology, CHU de Lille, Lille, France.

Compared to cerebral ischaemia, the frequency of spinal cord ischaemia is rare. Spinal infarcts lead to various types of neurological deficits, usually consisting of an abrupt and complete tetra- or paraplegia. Magnetic resonance imaging is the most valuable tool to show the infarct and to rule out other causes of acute spinal cord syndromes. Read More

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Association Between Soluble Receptor for Advanced Glycation End Product and Endogenous Secretory Soluble Receptor for Advanced Glycation End Product Levels and Carotid Atherosclerosis in Diabetes: A Systematic Review and Meta-analysis.

Can J Diabetes 2021 Jan 20. Epub 2021 Jan 20.

Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.

Background: The soluble receptor for advanced glycation end product (sRAGE) and endogenous secretory RAGE (esRAGE) are novel biomarkers that are associated with vascular disease. We carried out a systematic review to provide a more complete picture of sRAGE, esRAGE, carotid atherosclerosis and cardiovascular disease (CVD) in patients with diabetes.

Methods: We searched the Cochrane Library, PubMed and Embase databases. Read More

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January 2021

Total body irradiation causes a chronic decrease in antioxidant levels.

Sci Rep 2021 Mar 24;11(1):6716. Epub 2021 Mar 24.

Department of Radiobiology and Hygiene Management, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.

Ionizing radiation exposure may not only cause acute radiation syndrome, but also an increased risk of late effects. It has been hypothesized that induction of chronic oxidative stress mediates the late effects of ionizing radiation. However, only a few reports have analyzed changes in long-term antioxidant capacity after irradiation in vivo. Read More

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Aorto-carotid bypass for orthostatic mediated hypoperfusion transient ischaemic attacks: A case report.

Int J Surg Case Rep 2021 Mar 16;81:105780. Epub 2021 Mar 16.

Department of Cardiothoracic Surgery, The Prince Charles Hospital, Brisbane, Australia.

Introduction And Importance: Aorto-carotid bypass is a rare procedure. It is reported to be performed for management of cerebral malperfusion in the setting of supra-aortic branch vessel disease. Malperfusion requiring a bypass is largely secondary to dissection or vasculitis. Read More

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Association of Left Ventricular Systolic Function With Incident Heart Failure in Late Life.

JAMA Cardiol 2021 Mar 17. Epub 2021 Mar 17.

Department of Medicine, Cardiovascular Medicine Division, Brigham and Women's Hospital, Boston, Massachusetts.

Importance: Limited data exist regarding the association of subtle subclinical systolic dysfunction and incident heart failure (HF) in late life.

Objective: To assess the independent associations of subclinical impairments in systolic performance with incident HF in late life.

Design, Setting, And Participants: This study was a time-to-event analysis of participants without heart failure in the Atherosclerosis Risk in Communities (ARIC) study, a prospective, community-based cohort study, who underwent protocol echocardiography at the fifth study visit (January 1, 2011, to December 31, 2013). Read More

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Exertional chest pain is sometimes more than just coronary atherosclerosis.

Rev Port Cardiol 2021 Mar 11;40(3):245.e1-245.e5. Epub 2021 Mar 11.

Hospital Garcia de Orta, Almada, Portugal.

Clinical Case: A 64-year-old male, with cardiovascular risk factors and previous history of bilateral carpal tunnel syndrome, presented with exertional retrosternal pain. The resting echocardiogram was unremarkable. A stress echocardiogram with dobutamine revealed hypokinesis of the inferior wall, associated with angina, followed by ventricular tachycardia. Read More

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Wall shear stress estimated by 3D-QCA can predict cardiovascular events in lesions with borderline negative fractional flow reserve.

Atherosclerosis 2021 04 24;322:24-30. Epub 2021 Feb 24.

Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, UK; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK; Institute of Cardiovascular Sciences, University College London, London, UK. Electronic address:

Background And Aims: There is some evidence of the implications of wall shear stress (WSS) derived from three-dimensional quantitative coronary angiography (3D-QCA) models in predicting adverse cardiovascular events. This study investigates the efficacy of 3D-QCA-derived WSS in detecting lesions with a borderline negative fractional flow reserve (FFR: 0.81-0. Read More

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Multi-modality intravascular imaging for guiding coronary intervention and assessing coronary atheroma: the Novasight Hybrid IVUS-OCT system.

Minerva Cardiol Angiol 2021 Mar 11. Epub 2021 Mar 11.

Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, UK -

Intravascular imaging has evolved alongside interventional cardiology as an adjunctive tool for assessing plaque pathology and for guiding and optimising percutaneous coronary intervention (PCI) in challenging lesions. The two modalities which have dominated the field are intravascular ultrasound (IVUS), which relies on sound waves and optical coherence tomography (OCT), relying on light waves. These approaches however have limited efficacy in assessing plaque morphology and vulnerability that are essential for guiding PCI in complex lesions and identifying patient at risk that will benefit from emerging therapies targeting plaque evolution. Read More

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Calciprotein Particles: Balancing Mineral Homeostasis and Vascular Pathology.

Arterioscler Thromb Vasc Biol 2021 Mar 11:ATVBAHA120315697. Epub 2021 Mar 11.

Laboratory for Cardiovascular Regenerative Medicine, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, the Netherlands. (L.F., G.K.).

Hypercalcemia and hyperphosphatemia associate with an elevated risk of cardiovascular events, yet the pathophysiological basis of this association is unclear. Disturbed mineral homeostasis and the associated hypercalcemia and hyperphosphatemia may result in the formation of circulating calciprotein particles (CPPs) that aggregate the excessive calcium and phosphate ions. If not counteracted, the initially formed harmless amorphous spherical complexes (primary CPPs) may mature into damaging crystalline complexes (secondary CPPs). Read More

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Body Lateropulsion in Stroke: Case Report and Systematic Review of Stroke Topography and Outcome.

J Stroke Cerebrovasc Dis 2021 May 27;30(5):105680. Epub 2021 Feb 27.

Departments of Neurology and Emergency Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY 11203, USA; Jaffe Stroke Center, Maimonides Medical Center, Brooklyn, NY 11219, USA; Department of Neurology, King's County Hospital Center, Brooklyn, NY 11203, USA. Electronic address:

Introduction: Body lateropulsion (BLP) is seen in neurological lesions involving the pathways responsible for body position and verticality. We report a case of isolated body lateropulsion (iBLP) as the presentation of lateral medullary infarction and conducted a systematic literature review.

Methods: MEDLINE and EMBASE databases were searched up to December 3, 2020. Read More

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Dietary habits of patients with coronary artery disease in a tertiary-care hospital of Bangladesh: a case-controlled study.

J Health Popul Nutr 2021 Mar 1;40(1). Epub 2021 Mar 1.

Nutrition Officer, LabAid Cardiac Hospital, Dhaka, 1205, Bangladesh.

Background And Objectives: Globally, coronary artery disease (CAD) remains one of the leading causes of death, both in developed and less economically developed countries (LEDC) including Bangladesh. Diet plays a key role in the pathogenesis processes of atherosclerosis and coronary artery disease (CAD). The purpose of this study was to assess the dietary habit of heart disease cases that had CAD against matched controls. Read More

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Strong enhancement on three-dimensional black-blood enhanced magnetic resonance imaging: Comparison intracranial stenosis and complete occlusion.

Eur J Radiol 2021 Apr 7;137:109580. Epub 2021 Feb 7.

Department of Radiology and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Republic of Korea.

Purpose: The purpose of this study was to evaluate contrast enhancement patterns on three-dimensional (3D) black blood (BB) contrast-enhanced magnetic resonance (MR) imaging in patients with occlusion or stenosis of the anterior intracranial artery.

Materials And Methods: From January 2018 to January 2020 we retrospectively reviewed stroke 3D BB contrast-enhanced MR imaging and MR angiography findings of patients visiting the emergency room for evaluation of non-traumatic brain lesions. In total, 92 patients with positive findings on 3D BB contrast-enhanced MR imaging were enrolled in this study. Read More

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The Contribution of Cerebral Vascular Neuropathology to Mild Stage of Alzheimer's Dementia Using the NACC Database.

Curr Alzheimer Res 2020 ;17(13):1167-1176

Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, University of New South Wales, Sydney, Australia.

Background: The interaction between cerebral vessel disease (CVD) pathology and Alzheimer's disease (AD) pathology in the development of dementia is controversial. We examined the association of cerebral vascular neuropathology and cerebrovascular risk factors with the mild stage of Alzheimer's dementia and cognitive function.

Methods: This cross-sectional study included men and women aged 60 years or over who had yearly clinical assessments and had agreed to brain autopsy at the time of death, and who contributed to data stored at the National Alzheimer's Coordinating Center (NACC) in the USA. Read More

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January 2020

Characterization of visual manifestations and identification of risk factors for permanent vision loss in patients with giant cell arteritis.

Clin Rheumatol 2021 Feb 12. Epub 2021 Feb 12.

Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Division of Internal Medicine, Department of Medicine, Hôpital du Sacré-Coeur de Montréal, University of Montreal, Montreal, QC, Canada.

Background/purpose: Permanent vision loss (PVL) is a feared complication and a leading cause of morbidity in giant cell arteritis (GCA). The objective of this study is to describe visual manifestations and identify risk factors of ocular involvement in GCA.

Methods: A retrospective database from a single vasculitis referral center was used. Read More

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February 2021

LDL Cholesterol Reduction Variability with Different Types and Doses of Statins in Monotherapy or Combined with Ezetimibe. Results from the Spanish Arteriosclerosis Society Dyslipidaemia Registry.

Cardiovasc Drugs Ther 2021 Feb 8. Epub 2021 Feb 8.

Endocrinology and Nutrition Department, Hospital Universitario del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain.

Purpose: Low-density lipoprotein (LDL) cholesterol reduction by statin therapy is dose-dependent, varies among different statins, and has wide inter-individual variability. The present study aimed to compare mean LDL cholesterol reduction and its variability achieved with different doses of the three statins most frequently used in monotherapy or combined with ezetimibe in a real clinical setting.

Methods: Of 5620 cases with primary hypercholesterolemia on the Spanish Arteriosclerosis Society Registry, 1004 with non-familial hypercholesterolemia and complete information on drug therapy and lipid profile were included. Read More

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February 2021

Horner's syndrome secondary to internal carotid artery occlusion.

BMJ Case Rep 2021 Feb 4;14(2). Epub 2021 Feb 4.

Internal Medicine Services, Ballarat Health Services, Ballarat, Victoria, Australia

Horner's syndrome results from interruption of the sympathetic innervation to the eye. This interruption may occur at three anatomical levels along the sympathetic trunk pathway. There are numerous causes of Horner's syndrome, including injury to the carotid artery, of which arterial dissection is the commonest pathology. Read More

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February 2021

A post-GWAS confirming the genetic effects and functional polymorphisms of AGPAT3 gene on milk fatty acids in dairy cattle.

J Anim Sci Biotechnol 2021 Feb 1;12(1):24. Epub 2021 Feb 1.

Department of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, National Engineering Laboratory for Animal Breeding, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, 100193, China.

Background: People are paying more attention to the healthy and balanced diet with the improvement of their living standards. Milk fatty acids (FAs) have been reported that they were related to some atherosclerosis and coronary heart diseases in human. In our previous genome-wide association study (GWAS) on milk FAs in dairy cattle, 83 genome-wide significant single nucleotide polymorphisms (SNPs) were detected. Read More

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February 2021

Plaque Wall Distribution Pattern of the Atherosclerotic Middle Cerebral Artery Associates With the Circle of Willis Completeness.

Front Neurol 2020 11;11:599459. Epub 2021 Jan 11.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong.

Investigating the relevance of the incomplete circle of Willis (COW) to the plaque wall distribution in the atherosclerotic middle cerebral arteries (MCAs) through utilizing high-resolution magnetic resonance imaging (HR-MRI), and its potential clinical impact. This hospital-based study enrolled consecutive adult patients with acute ischemic stroke or transient ischemic attack, who received a 3.0T Achieva MR system scanning. Read More

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January 2021

A Case of Successful Intravenous Thrombolysis Bridged with Repeated Endovascular Treatment in Acute Basilar Artery Occlusion.

Case Rep Neurol 2020 Sep-Dec;12(Suppl 1):34-40. Epub 2020 Dec 14.

115 People's Hospital, Ho Chi Minh City, Vietnam.

Acute basilar artery occlusion (BAO) is a neurological emergency that has a high rate of mortality and poor functional outcome. Endovascular therapy (ET) is the gold standard therapy for large vessel occlusion stroke of the anterior circulation. Whether ET can also be effectively and safely performed in early recurrent large vessel occlusion, especially in BAO, is unclear. Read More

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December 2020

Al-hijamah (the triple S treatment of prophetic medicine) exerts cardioprotective, tissue-protective and immune potentiating effects in thalassemic children: a pilot clinical trial.

Am J Blood Res 2020 15;10(6):447-458. Epub 2020 Dec 15.

Prophetic Medicine Course and Research Group, Taibah College of Medicine Al-Madinah Al-Munawwarah, Saudi Arabia.

Thalassemia is a major health problem in affected children due to iron overload, increased oxidative stress, atherogenic lipid profile and tissue-damage. This study aims at investigating the cardioprotective and tissue-protective benefits of Al-hijamah and their impact on cell-mediated immunity for treating thalassemic children. This study aimed also at investigating the tissue-clearance principle of Taibah mechanism: whenever pathological substances are to be cleared from the human body, Al-hijamah is indicated. Read More

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December 2020

Impact of proximal and distal cuff inflation on brachial artery endothelial function in healthy individuals.

Eur J Appl Physiol 2021 Apr 23;121(4):1135-1144. Epub 2021 Jan 23.

School of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.

Purpose: In this study, we examined whether the decrease in endothelial function associated with short-term exposure to elevated retrograde shear rate (SR), could be prevented when combined with a concurrent drop in transmural pressure in humans.

Methods: Twenty-five healthy individuals reported to our laboratory on three occasions to complete 30-min experimental conditions, preceded and followed by assessment of endothelial function using flow-mediated dilation (FMD). We used cuff inflation for 30-min to manipulate retrograde SR and transmural pressure in the brachial artery. Read More

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Excision and End-to-End Anastomosis of a Giant Partially Thrombosed Cervical Internal Carotid Artery Aneurysm Mimicking a Neck Tumor: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 Jan 16. Epub 2021 Jan 16.

Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, Florida.

Aneurysms of the cervical internal carotid artery (ICA) are a rare entity1,2 accounting for less than 0.2% to 0.5% of all carotid surgeries3 and less than 1% of all arterial aneurysms. Read More

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January 2021

Evolution of coronary artery calcium and absolute myocardial perfusion after percutaneous revascularization: A 3-year serial hybrid [O]HO PET/CT imaging study.

Atherosclerosis 2021 02 19;318:22-31. Epub 2020 Dec 19.

Department of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. Electronic address:

Background And Aims: The value of serial coronary artery calcium (CAC) scores to predict changes in absolute myocardial perfusion and epicardial vasomotor function is poorly documented. This study explored the association between progression of CAC score and changes in absolute myocardial perfusion.

Methods: Fifty-three patients (26% female) with de novo single-vessel coronary artery disease underwent [O]HO positron emission tomography/computed tomography at 1 month (baseline), 1 year, and 3 years after complete revascularization with percutaneous coronary intervention (PCI) to assess CAC scores, hyperemic myocardial blood flow (hMBF), coronary flow reserve (CFR) and cold pressor test MBF (CPT-MBF), within the context of the VANISH trial. Read More

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February 2021

Familial hypercholesterolemia in Mexico: Initial insights from the national registry.

Authors:
Roopa Mehta Alexandro J Martagon Gabriela A Galan Ramirez Neftali Eduardo Antonio-Villa Arsenio Vargas-Vázquez Daniel Elias-Lopez Gustavo Gonzalez-Retana Bethsabel Rodríguez-Encinas Jose J Ceballos-Macías Alejandro Romero-Zazueta Rocio Martinez-Alvarado Julieta D Morales-Portano Humberto Alvarez-Lopez Leobardo Sauque-Reyna Laura G Gomez-Herrera Luis E Simental-Mendia Humberto Garcia-Aguilar Elizabeth Ramirez-Cooremans Berenice Peña-Aparicio Victoria Mendoza-Zubieta Perla A Carrillo-Gonzalez Aldo Ferreira-Hermosillo Nacu Caracas-Portilla Guadalupe Jimenez-Dominguez Alinna Y Ruiz-Garcia Hector E Arriaga-Cazares Jesus R Gonzalez-Gonzalez Carla V Mendez-Valencia Francisco G Padilla Ramon Madriz-Prado Manuel O De Los Rios-Ibarra Alejandra Vazquez-Cardenas Ruy D Arjona-Villicaña Karina J Acevedo-Rivera Ricardo Allende-Carrera Jose A Alvarez Jose C Amezcua-Martinez Manuel de Los Reyes Barrera-Bustillo Gonzalo Carazo-Vargas Roberto Contreras-Chacon Mario H Figueroa-Andrade Ashanty Flores-Ortega Hector Garcia-Alcala Laura E Garcia de Leon Berenice Garcia-Guzman Jose J Garduño-Garcia Juan C Garnica-Cuellar Jose R Gomez-Cruz Anell Hernandez-Garcia Jesus R Holguin-Almada Ursulo Juarez-Herrera Fabiola Lugo-Sobrevilla Eduardo Marquez-Rodriguez Cristina Martinez-Sibaja Alma B Medrano-Rodriguez Jose C Morales-Oyervides Daniel I Perez-Vazquez Eduardo A Reyes-Rodriguez Ma Ludivina Robles-Osorio Juan Rosas-Saucedo Margarita Torres-Tamayo Luis A Valdez-Talavera Luis E Vera-Arroyo Eloy A Zepeda-Carrillo Carlos A Aguilar-Salinas

J Clin Lipidol 2021 Jan-Feb;15(1):124-133. Epub 2020 Dec 16.

Unidad de Investigación de Enfermedades Metabolicas, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, México City, Mexico; Departamento de Endocrinologia y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubiran, Mexico City, Mexico; Direccion de Nutricion, Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubiran, Mexico City, Mexico; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo Leon, Mexico. Electronic address:

Background: Familial hypercholesterolemia (FH) remains underdiagnosed and undertreated.

Objective: Report the results of the first years (2017-2019) of the Mexican FH registry.

Methods: There are 60 investigators, representing 28 federal states, participating in the registry. Read More

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December 2020