1,218,431 results match your criteria associated factors


Perinatal mortality audits and reporting of perinatal deaths: systematic review of outcomes and barriers.

J Perinat Med 2022 Jan 26. Epub 2022 Jan 26.

Department of Obstetrics and Gynaecology, School of Medicine and Health, University College Cork, Cork, Ireland.

Background: Perinatal deaths are a devastating experience for all families and healthcare professionals involved. Audit of perinatal mortality (PNM) is essential to better understand the factors associated with perinatal death, to identify key deficiencies in healthcare provision and should be utilised to improve the quality of perinatal care. However, barriers exist to successful audit implementation and few countries have implemented national perinatal audit programs. Read More

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January 2022

Mitral Annulus Calcification and Cardiac Conduction Disturbances: A DANCAVAS Sub-study.

J Cardiovasc Imaging 2022 Jan;30(1):62-75

Department of Cardiology, Odense University Hospital, Odense, Denmark.

Background: Due to its location very close to the bundle of His, mitral annulus calcification (MAC) might be associated with the development of atrioventricular (AV) conduction disturbances. This study assessed the association between MAC and AV conduction disturbances identified by cardiac implantable electronic device (CIED) use and electrocardiographic parameters. The association between MAC and traditional cardiovascular risk factors was also assessed. Read More

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January 2022

Risk Factors and Consequences of Acute Kidney Injury After Noncardiac Surgery in Children.

Anesth Analg 2022 Jan 27. Epub 2022 Jan 27.

From the Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio; and the Ohio State University, Columbus, Ohio.

Background: Postoperative acute kidney injury (AKI) is a serious complication that is associated with prolonged hospital stay, high risk of short-term postsurgical mortality, need for dialysis, and possible progression to chronic kidney disease. To date, very little data exist on the risk of postoperative AKI among children undergoing noncardiac surgical procedures. We used data from a large multicenter cohort to determine the factors associated with AKI among children who underwent inpatient noncardiac surgical procedures and its impact on the postoperative course. Read More

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January 2022

Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients.

J Innate Immun 2022 Jan 27:1-16. Epub 2022 Jan 27.

Department of Biochemistry, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.

Neutrophil extracellular traps (NETs) have been described as a potential trigger of severe COVID-19. NETs are known as extracellular DNA fibers released by neutrophils in response to infection. If the host is unable to balance efficient clearance of NETs by dornases (DNases), detrimental consequences occur. Read More

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January 2022

Risk Factors for Surgery in Pediatric Patients with Crohn's Disease.

Med Princ Pract 2022 Jan 27. Epub 2022 Jan 27.

I Objective: Pediatric Crohn's disease has a more aggressive phenotype and course than in adults. Many patients develop complications that require surgery. The aim of this study was to identify the factors associated with increased risk for surgical intervention in pediatric patients with Crohn's disease. Read More

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January 2022

DIET AND LIFESTYLE HABITS IN EARLY-ONSET COLORECTAL CANCER. A PILOT CASE-CONTROL STUDY.

Dig Dis 2022 Jan 27. Epub 2022 Jan 27.

Background: Early-onset Colorectal Cancer (eoCRC), defined as a CRC in patients younger than 50 years old, shows an increasing incidence worldwide in the latest years. The role of exogenous factors associated with CRC has been largely overlooked in eoCRC. Here, we conducted a case-control study to evaluate the diet and the lifestyle habits in an Italian population of patients with eoCRC, compared to age-matched healthy controls (HCs). Read More

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January 2022

Podocyte protection by Angptl3 knockout via inhibiting ROS/GRP78 pathway in LPS-induced acute kidney injury.

Int Immunopharmacol 2022 Jan 24;105:108549. Epub 2022 Jan 24.

Department of Nephrology, Children's Hospital of Fudan University, Shanghai, 201102, China; Kidney Development and Pediatric Kidney Disease Research Center, Shanghai, 201102, China. Electronic address:

Acute kidney injury (AKI) caused by sepsis has a high incidence and poor prognosis. Thus, novel strategies that minimize AKI are urgently needed. In our previous research, we found that angiopoietin-like protein 3 (Angptl3) knockout exerts protective effects on kidney injury in adriamycin nephropathy. Read More

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January 2022

Associated factors, assessment, management, and outcomes of patients who present to the emergency department for acute exacerbation of chronic obstructive pulmonary disease: A scoping review.

Respir Med 2022 Jan 21;193:106747. Epub 2022 Jan 21.

Darling Downs Hospital and Health Service, Toowoomba, Australia.

Objective: The purpose of the scoping review was to examine the extant literature for factors contributing to presentations of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) to Emergency Departments (ED).

Methods: The review followed Arksey and O'Malley, and Levac's frameworks supplemented with the PRISMA-ScR checklist. We searched Cochrane Library, CINAHL, JBI, and PubMed from January 1, 2008 to March 23, 2020 for inclusions. Read More

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January 2022

Disparities in Demographics and Outcomes Based on Trauma Center Ownership.

J Surg Res 2022 Jan 24;273:132-137. Epub 2022 Jan 24.

Department of Surgery, University of Florida, Jacksonville, Florida. Electronic address:

Introduction: Ownership may influence trauma center (TC) location. For-profit (FP) TCs require a favorable payor mix to thrive, whereas not-for-profit (NFP) centers may rely on government funding, grants, and patient volume. We hypothesized that the demographics of trauma patients would be different for NFP and FP TCs due to ownership type. Read More

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January 2022

Prevalence and risk factors of lower limb amputations in patients with diabetic foot ulcers: A systematic review and meta-analysis.

Diabetes Metab Syndr 2022 Jan 14;16(2):102397. Epub 2022 Jan 14.

Translational Research in Endocrinology and Diabetes, College of Medicine and Dentistry, James Cook University, Australia; Department of Diabetes and Endocrinology, Townsville University Hospital, Australia. Electronic address:

Background And Aims: The study aimed at determining prevalence and risk factors (RFs) of diabetic lower limb amputations (LLAs).

Methods: Electronic databases including PubMed, Medline, Web of Science, and Cochrane Library were searched from January 2003 to April 2021.

Results: Sixteen full-text published studies were reviewed. Read More

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January 2022

Decreased risk of COVID-19 pneumonia in children and adolescents during the Delta variant emergence.

Public Health 2021 Dec 28;204:9-11. Epub 2021 Dec 28.

Facultad de Ingeniería Civil, Universidad de Colima, Km. 9 Carretera Colima-Coquimatlán, Coquimatlán, C.P. 28400, Colima, México. Electronic address:

Objectives: This study aimed to evaluate factors associated with the risk of COVID-19 pneumonia in children (aged <10 years) and adolescents (aged 10-19 years) before (March 2020-April 2021) and during (May-July 2021) the Delta (B.1.617. Read More

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December 2021

Relationships between Thai fathers' self-efficacy to support breastfeeding and exclusive breastfeeding duration.

Midwifery 2022 Jan 19;106:103261. Epub 2022 Jan 19.

Department of Human Development Nursing Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, USA.

Objective: To determine associations between Thai fathers' self-efficacy to support exclusive breastfeeding and exclusive breastfeeding duration.

Design: A descriptive quantitative design was used.

Participants And Settings: The study sample consisted of 205 father-mother couples (410 participants) with an infant who was 6 months old. Read More

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January 2022

Tissue-specific accumulation, transformation, and depuration of fipronil in adult crucian carp (Carassius auratus).

Ecotoxicol Environ Saf 2022 Jan 24;232:113234. Epub 2022 Jan 24.

Key Laboratory of Agro-ecological Processes in Subtropical Regions, Changsha Research Station for Agricultural & Environmental Monitoring, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China. Electronic address:

Accumulation and biotransformation of pesticides in fish tissues are essential to assess their toxicity and associated human exposure risk. The mechanisms on time-dependent and tissue-specific accumulation and transformation of fipronil in adult fish are limited. An experiment consisting of 25-d uptake of fipronil at two levels (10 and 50 μg/L) and 25-d depuration in adult crucian carp (Carassius auratus) was conducted. Read More

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January 2022

Age and indication for pediatric septoplasty in the NSQIP-P database.

Int J Pediatr Otorhinolaryngol 2022 Jan 19;154:111046. Epub 2022 Jan 19.

Department of Otolaryngology - Head and Neck Surgery, Jacobs School of Medicine & Biomedical Sciences at the University at Buffalo, Buffalo, NY, USA. Electronic address:

Introduction: Pediatric septoplasty has been a historically controversial topic in the field of otolaryngology. Past recommendations avoided reconstruction during development because of the potential for growth changes after intervention that may require later revision surgery. Recent studies have considered early operation to avoid further growth complications, pointing at changing trends in the field. Read More

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January 2022

Combination of ultra-purified stem cells with an in situ-forming bioresorbable gel enhances intervertebral disc regeneration.

EBioMedicine 2022 Jan 24;76:103845. Epub 2022 Jan 24.

Department of Orthopedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan; Department of Advanced Medicine for Spine and Spinal Cord Disorders, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N15W7, Sapporo, Hokkaido 060-8638, Japan. Electronic address:

Background: Lumbar intervertebral disc (IVD) herniations are associated with significant disability. Discectomy is the conventional treatment option for IVD herniations but causes a defect in the IVD, which has low self-repair ability, thereby representing a risk of further IVD degeneration. An acellular, bioresorbable, and good manufacturing practice (GMP)-compliant in situ-forming gel, which corrects discectomy-associated IVD defects and prevents further IVD degeneration had been developed. Read More

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January 2022

Reduced chromatin accessibility to CD4 T cell super-enhancers encompassing susceptibility loci of rheumatoid arthritis.

EBioMedicine 2022 Jan 24;76:103825. Epub 2022 Jan 24.

Department of Immunology, Mayo Clinic School of Medicine and Sciences, Rochester, MN, United States; Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Stanford, CA, United States; Department of Medicine, Palo Alto Veterans Administration Healthcare System, Palo Alto, CA; Division of Rheumatology, Department of Medicine, Mayo Clinic School of Medicine and Sciences, Rochester, MN, United States. Electronic address:

Background: Rheumatoid arthritis (RA) is an inflammatory disease that manifests as a preclinical stage of systemic autoimmunity followed by chronic progressive synovitis. Disease-associated genetic SNP variants predominantly map to non-coding, regulatory regions of functional importance in CD4 T cells, implicating these cells as key regulators. A better understanding of the epigenome of CD4 T cells holds the promise of providing information on the interaction between genetic susceptibility and exogenous factors. Read More

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January 2022

Repeat Anatomical Surveys Performed for an Initial Incomplete Study: Sonographer and Physician Factor.

Am J Obstet Gynecol MFM 2022 Jan 24:100567. Epub 2022 Jan 24.

Denver Health and Hospital Authority, Denver, CO; University of Colorado School of Medicine, Aurora, CO.

Background: Repeat obstetrical anatomical surveys are often performed for an initial incomplete study despite conflicting evidence.

Objective: To determine the frequency and yield of a repeat obstetrical anatomical survey performed for an initial incomplete study, and to determine patient and provider factors associated with the recommendation for a second study.

Study Design: Retrospective cohort study over 10 years of women having an initial anatomical survey at 18 - 21 6/7 weeks at a single non-referral county hospital. Read More

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January 2022

Racial and Sociodemographic Disparities in the Detection of Narrow Angles Prior to Primary Angle Closure Glaucoma in the United States.

Ophthalmol Glaucoma 2022 Jan 24. Epub 2022 Jan 24.

Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine at the University of Southern California, Los Angeles, California. Electronic address:

Purpose: To assess the proportion of newly diagnosed cases of PACG with and without prior diagnosis of anatomical narrow angles (ANA) and identify sociodemographic risk factors for late detection (PACG without prior ANA diagnosis).

Design: Retrospective cohort study.

Methods: 102,617 patients with PACG were identified from the Optum Clinformatics® Data Mart Database (2007-2019). Read More

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January 2022

Age-dependent non-linear neuroplastic effects of cathodal tDCS in the elderly population; a titration study.

Brain Stimul 2022 Jan 24. Epub 2022 Jan 24.

Department of Psychology and Neurosciences, Leibniz Research Center for Working Environment and Human Factors, Dortmund, Germany; Department of Neurology, University Medical Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany. Electronic address:

Background: Neuromodulatory effects of transcranial direct current stimulation (tDCS) in older humans have shown heterogeneous results, possibly due to sub-optimal stimulation protocols associated with limited knowledge about optimized stimulation parameters in this age group. We systematically explored the association between the stimulation dosage of cathodal tDCS and induced after-effects on motor cortex excitability in the elderly.

Method: Thirty-nine healthy volunteers in two age groups, namely Pre-Elderly (50-65 years) and Elderly (66-80 years), participated in the study. Read More

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January 2022

A Large Series of True Pancreaticoduodenal Artery Aneurysms.

J Vasc Surg 2022 Jan 24. Epub 2022 Jan 24.

Division of Vascular Surgery and Endovascular Therapy, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Introduction: True pancreaticoduodenal artery aneurysms (PDAA) are rare and prior reports often fail to distinguish true aneurysms from pseudoaneuryms. We sought to characterize all patients who presented to our health-system from 2004-2019 with true PDAA, with a focus on risk factors, interventions, and patient outcomes.

Methods: Patients were identified by querying a single health-system PACS database for radiographic reports noting a PDAA. Read More

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January 2022

The Relationship Between Neighborhood Disadvantage and Kidney Disease Progression in the Chronic Kidney Disease in Children (CKiD) Cohort.

Am J Kidney Dis 2022 Jan 24. Epub 2022 Jan 24.

Associate Professor, Division of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD.

Rationale & Objective: To examine the relationship between neighborhood poverty and deprivation, chronic kidney disease (CKD) comorbidities, and disease progression in children with CKD.

Study Design: Observational cohort study.

Setting & Participants: Children with mild to moderate CKD enrolled in the CKiD study with available United States Census data. Read More

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January 2022

Anxiety, Depression and PTSD in Children and Adolescents following the Beirut Port Explosion.

J Affect Disord 2022 Jan 24. Epub 2022 Jan 24.

Department of Epidemiology and Population Health, Faculty of Health Sciences, American University of Beirut.. Electronic address:

Background: On August 4, 2020, Beirut's port experienced one of the strongest non-nuclear explosions in history, killing approximately 200 people, displacing 300,000 persons, and injuring more than 1000 children.

Methods: An online anonymous survey assessed the prevalence of probable mental health disorders (MHDs) and impact of blast-related and other factors controlling for sociodemographics in 801 children aged 8 to 17 years old.

Results: About two thirds (64%) were screened positive for probable anxiety using the Screen for Childhood Anxiety Related Disorder, 52% for probable PTSD using CRIES-13, and 33% for probable depression using the Mood and Feelings Questionnaire (MFQ). Read More

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January 2022

Transformation in culinary behaviour during the COVID-19 pandemic: In-depth interviews with food gatekeepers in urban India.

Appetite 2022 Jan 24:105948. Epub 2022 Jan 24.

Department of Community Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India. Electronic address:

COVID-19 and its associated regulatory measures including lockdowns, curfews, and physical distancing norms have significantly affected individual's dietary and culinary behaviours. Although there is ample empirical evidence available on dietary changes within the Indian context, very limited evidence exists about the factors influencing these dietary modifications and changes in culinary behaviours during COVID-19 lockdown. Therefore, the aim of this qualitative study was to explore the views of Indian household food gatekeepers towards meal planning, food purchasing, and meal preparation during the pandemic and its associated lockdowns. Read More

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January 2022

Evaluation of disease severity during SARS-COV-2 reinfection, January 2020 to April 2021, England: an observational study.

J Infect 2022 Jan 24. Epub 2022 Jan 24.

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

Objective: We aimed to look at the burden of disease caused by SARS-COV-2 reinfections and identified potential risk factors for disease severity.

Methods: We used national surveillance data to collect information on all SARS-CoV-2 primary infection and suspected reinfection cases between January 2020 until early May 2021. Reinfection cases were positive COVID-19 PCR or antigen test, 90 days after their first COVID-19 positive test. Read More

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January 2022

Bioaugmented removal of 17β-estradiol, nitrate and Mn(II) by [email protected] cob immobilized bioreactor: Performance optimization, mechanism, and microbial community response.

Environ Pollut 2022 Jan 24:118896. Epub 2022 Jan 24.

School of Environmental and Municipal Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, China; Shaanxi Key Laboratory of Environmental Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, China.

The coexistence of nitrate and endocrine substances (EDCs) in groundwater is of global concern. Herein, an efficient and stable [email protected] cob ([email protected] cob) bioreactor immobilized with Zoogloea sp. was designed for the simultaneous removal of 17β-estradiol (E2), nitrate and Mn(II). Read More

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January 2022

Medication adherence in young adults with youth-onset type 2 diabetes: iCount, an observational study.

Diabetes Res Clin Pract 2022 Jan 24:109216. Epub 2022 Jan 24.

State University of New York (SUNY) Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. Electronic address:

Aims: To assess prevalence of, and factors associated with, medication adherence of young adults with youth-onset type 2 diabetes.

Methods: Oral hypoglycaemia agent (OHA) adherence was measured with unannounced telephone pill counts, insulin adherence was self-reported. Those taking ≥ 80% of pills/insulin were classified "high-adherent," <80% of pills/insulin "low-adherent. Read More

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January 2022

New insights on in vitro biotransformation of anticoagulant rodenticides in fish.

Chemosphere 2022 Jan 24:133727. Epub 2022 Jan 24.

German Environment Agency, Section IV 1.2 Biocides, 06813, Dessau-Rosslau, Germany.

The assessment of the bioaccumulation potential of chemicals is an essential and mandatory part of their regulatory environmental risk and hazard assessment. So far, in vitro data on fish metabolism is rarely available for biocidal active substances such as anticoagulant rodenticides. In this case study we present in vitro biotransformation rates of eight biocidal and one pharmaceutical anticoagulants in rainbow trout (Oncorhynchus mykiss) liver subcellular S9 fraction (RT-S9) determined following the Organisation for Economic Co-operation and Development test guideline 319B method at two different incubation temperatures (i. Read More

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January 2022

Do preoperative factors and implant design features influence humeral stem extraction efforts?

J Shoulder Elbow Surg 2022 Jan 24. Epub 2022 Jan 24.

Background: Variations in humeral component designs in hemiarthroplasty and anatomic total shoulder arthroplasty cases can impact the degree of difficulty during a revision surgery that necessitates the removal of the humeral stem. However, no metric exists to define stem extraction effort nor to identify associated factors that contribute to extraction difficulty. The purpose of this study is to describe a method to quantify stem extraction difficulty and to define features that will impact the effort during stem removal. Read More

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January 2022

Associations of muscle mass and grip strength with severe NAFLD: a prospective study of 333,295 UK Biobank participants.

J Hepatol 2022 Jan 24. Epub 2022 Jan 24.

Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK. Electronic address:

Background & Aim: Cross-sectional studies have shown lower muscle mass and strength as risk factors for non-alcoholic fatty liver disease (NAFLD). However, the evidence from prospective studies is limited. This study examined both the strength and pattern of the associations between these two physical capability markers and severe NAFLD in the UK Biobank study. Read More

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January 2022

Contraception Information on the Websites of Student Health Centers in the United States.

Contraception 2022 Jan 24. Epub 2022 Jan 24.

Health Equity Institute, Department of Economics, San Francisco State University, CA, U.S.A. Electronic address:

Objective: As University Student Health Centers are considered reputable sources of information by many young adults, we evaluate the presence of contraceptive information on their websites.

Study Design: We used a software tool (Quantitative Measures of Online Health Information), designed for public health research to examine online information access on four broad categories of contraception and reproductive health (LARC/injectables, Contraception, Condom, Pap test) on student health center websites from all (591) public four-year universities across the U.S. Read More

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January 2022