11,092 results match your criteria associated augmentation

Q/Is ketamine effective and safe for treatment-resistant depression?

J Fam Pract 2021 Apr;70(3):E1-E3

Valley Family Medicine Residency, University of Washington at Valley, Renton.

MAYBE, but it's too soon to tell. There is limited evidence that ketamine by itself is effective in the very short term. Single-dose intravenous (IV) ketamine is more likely than placebo (odds ratio = 11-13) to produce improvement (> 50%) in standardized depression scores in 1 to 3 days, lasting up to a week. Read More

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Effects of enhanced versus reduced vasodilating treatment on brachial and central blood pressure in patients with chronic kidney disease: a randomized controlled trial.

J Hypertens 2021 Jul 23. Epub 2021 Jul 23.

Department of Renal Medicine, Aarhus University Hospital Comparative Medicine Lab, Department of Clinical Medicine, Aarhus University Department of Cardiology, Aarhus University Hospital Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Background: Blood pressure (BP) control is important in chronic kidney disease (CKD), but a reduction in brachial BP may not mirror changes in central aortic BP (cBP) during antihypertensive medication. We hypothesize that a fall in cBP is better reflected during enhanced vasodilation treatment (EVT) compared with reduced vasodilation treatment (RVT) because of different hemodynamic actions of these interventions.

Methods: Eighty-one hypertensive CKD stage 3-4 patients (mean measured glomerular filtration rate 36 ml/min per 1. Read More

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Peripheral microcirculatory abnormalities are associated with cardiovascular risk in systemic sclerosis: a nailfold video capillaroscopy study.

Clin Rheumatol 2021 Jul 27. Epub 2021 Jul 27.

Fourth Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Konstantinoupoleos Str. 49, Thessaloniki, Greece.

Introduction: Microvascular dysfunction is the key element in the pathogenesis of systemic sclerosis (SSc), whereas the contribution of large and medium size vessel abnormalities is yet to be established. The aim of the present study is to assess the association between micro- and macrovascular function by utilizing a broad spectrum of assessments of vascular performance.

Methods: We included consecutive, consenting SSc patients who underwent nailfold video capillaroscopy (NVC) for microcirculation evaluation. Read More

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Breakage of sliding hip screw after fixation of pertrochanteric hip fracture: A rare complication.

Int J Surg Case Rep 2021 Jul 22;85:106226. Epub 2021 Jul 22.

Division of Orthopedic Surgery, Lebanese University, Faculty of Medical Sciences, Beirut, Lebanon.

Introduction: The authors report a rare case of lag screw breakage in a patient treated using locking DHS with home-made trochanteric stabilizing plate (TSP) for pertrochanteric hip fracture.

Case Presentation: A 67 year-old female was operated for pertrochanteric hip fracture with incompetent lateral wall using locking DHS with home-made TSP. At seven months postoperative, there was radiographic nonunion with breakage of the sliding lag screw. Read More

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Tympanoplasty with an Intact Stapes Superstructure in Chronic Otitis Media.

J Int Adv Otol 2021 Jul;17(4):282-287

Department of Otorhinolaryngology, Head and Neck Surgery, Spitalstrasse, Luzern, Switzerland.

Background: The objective of our study was to ascertain the functional results in terms of air bone gap (ABG) closure over 4 frequencies (0.5, 1, 2, 3 kHz) in patients with chronic otitis media (COM) that underwent tympanoplasty in the presence of a mobile stapes superstructure, and in particular excluding those cases in which the malleus was used in the reconstruction.

Methods: A retrospective review of our database between January 1, 2006 and June 1, 2018 identified all cases that underwent one of 3 reconstructive options: the classic Type III tympanoplasty in an open-cavity setting; the "stapes augmentation" (SA) type reconstruction where the stapes superstructure is augmented to the drum by an interposing partial ossiculoplasty of either autologous bone, cartilage, or prosthetic material; and the use of a total articular replacement prosthesis (TORP) from the stapes footplate to the drum in the presence of an intact superstructure. Read More

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Context-dependent social benefits drive cooperative predator defense in a bird.

Curr Biol 2021 Jul 15. Epub 2021 Jul 15.

School of Biological Sciences, Monash University, Clayton, VIC 3800, Australia.

Understanding the major evolutionary transition from solitary individuals to complex societies is hampered by incomplete insight into the drivers of living in cooperative groups. This may be because the benefits of sociality can derive from group living itself (e.g. Read More

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Chromosome 10q26-driven age-related macular degeneration is associated with reduced levels of in human retinal pigment epithelium.

Proc Natl Acad Sci U S A 2021 Jul;118(30)

Steele Center for Translational Medicine, John A. Moran Eye Center, University of Utah, Salt Lake City, UT 84132;

Genome-wide association studies have identified the chromosome 10q26 (Chr10) locus, which contains the age-related maculopathy susceptibility 2 () and high temperature requirement A serine peptidase 1 () genes, as the strongest genetic risk factor for age-related macular degeneration (AMD) [L.G. Fritsche et al. Read More

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Novel Poly(ionic liquid) Augmented Membranes for Unconventional Aqueous Phase Applications in Fractionation of Dyes and Sugar.

Polymers (Basel) 2021 Jul 19;13(14). Epub 2021 Jul 19.

Ralph E Martin College of Chemical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.

Poly(ionic) liquid (PIL) augmented membranes were fabricated through self-polymerization of 2-vinyl pyridine and 4-vinyl pyridine followed by dopamine triggered polymerization and bridging with inert polyamide support. The resulting membranes acquired a positive surface charge with a high degree of hydrophilicity. Fourier transformed Infra-red (FTIR) and Energy dispersive X-ray (EDX) spectroscopic investigation revealed the successful augmentation of PIL surface layer, whereas surface morphology was investigated through scanning electron microscopy (SEM) imaging. Read More

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Sclerosing lipogranuloma of the penis: a narrative review of complications and treatment.

Transl Androl Urol 2021 Jun;10(6):2705-2714

Department of Urology, University of Lisbon, School of Medicine, Santa Maria Teaching Hospital, Lisbon, Portugal.

Objective: Sclerosing lipogranuloma of the penis is a relatively rare disorder associated with injection of illicit foreign materials for penile augmentation. We aim to report the clinical presentation, diagnosis, treatment, and outcomes of patients with this condition, and to review the most relevant literature currently available.

Background: Injection of mineral oil into the subcutaneous tissues of the penis for augmentation has been practiced since ancient times. Read More

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The American Society of Pain and Neuroscience (ASPN) Best Practices and Guidelines for the Interventional Management of Cancer-Associated Pain.

J Pain Res 2021 16;14:2139-2164. Epub 2021 Jul 16.

Department of Anesthesiology, Pain and Perioperative Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Moderate to severe pain occurs in many cancer patients during their clinical course and may stem from the primary pathology, metastasis, or as treatment side effects. Uncontrolled pain using conservative medical therapy can often lead to patient distress, loss of productivity, shorter life expectancy, longer hospital stays, and increase in healthcare utilization. Various publications shed light on strategies for conservative medical management for cancer pain and a few international publications have reviewed limited interventional data. Read More

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Association of Body Composition with Arterial Stiffness in Long-lived People.

Arq Bras Cardiol 2021 Jul 16. Epub 2021 Jul 16.

Universidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.

Background: Arterial stiffness, obesity and sarcopenia correlate with each other and with cardiac outcomes in younger adults. However, there is little evidence of the association between body composition and markers of central arteries stiffness in long-lived people.

Objective: To evaluate the relationship between arterial stiffness and body composition in functionally independent long-lived individuals. Read More

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Adverse reactions associated with perioral rejuvenation using laser, fat and hyaluronic acid: systematic review.

Br J Oral Maxillofac Surg 2021 Apr 21. Epub 2021 Apr 21.

Poole Hospital NHS Foundation Trust.

Perioral rejuvenation is carried out by surgical and non-surgical tools. The common procedures are laser resurfacing and volumanisation using alloplastic fillers or autogenous fat. Nonetheless, any such procedures are associated with complications. Read More

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Metformin prevents p-tau and amyloid plaque deposition and memory impairment in diabetic mice.

Exp Brain Res 2021 Jul 20. Epub 2021 Jul 20.

Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil.

Insulin deficiency or resistance can promote dementia and hallmarks of Alzheimer's disease (AD). The formation of neurofibrillary tangles of p-TAU protein, extracellular Aβ plaques, and neuronal loss is related to the switching off insulin signaling in cognition brain areas. Metformin is a biguanide antihyperglycemic drug used worldwide for the treatment of type 2 diabetes. Read More

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Longitudinal genome-wide methylation study of PTSD treatment using prolonged exposure and hydrocortisone.

Transl Psychiatry 2021 Jul 13;11(1):398. Epub 2021 Jul 13.

Department of Psychiatry, James J. Peters VA Medical Center, Bronx, NY, USA.

Epigenetic changes are currently invoked as explanations for both the chronicity and tenacity of post-traumatic stress disorder (PTSD), a heterogeneous condition showing varying, sometimes idiosyncratic responses to treatment. This study evaluated epigenetic markers in the context of a randomized clinical trial of PTSD patients undergoing prolonged-exposure psychotherapy with and without a hydrocortisone augmentation prior to each session. The purpose of the longitudinal epigenome-wide analyses was to identify predictors of recovery (from pretreatment data) or markers associated with symptom change (based on differences between pre- and post-therapy epigenetic changes). Read More

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Molecular Mechanisms of Palmitic Acid Augmentation in COVID-19 Pathologies.

Int J Mol Sci 2021 Jul 1;22(13). Epub 2021 Jul 1.

Department of Biological Sciences, Seton Hall University, South Orange, NJ 07079, USA.

The coronavirus disease 2019 (COVID-19) pandemic has claimed over 2.7 million lives globally. Obesity has been associated with increased severity and mortality of COVID-19. Read More

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Amorphous-Crystalline Calcium Phosphate Coating Promotes In Vitro Growth of Tumor-Derived Jurkat T Cells Activated by Anti-CD2/CD3/CD28 Antibodies.

Materials (Basel) 2021 Jul 1;14(13). Epub 2021 Jul 1.

Center for Immunology and Cellular Biotechnology, Immanuel Kant Baltic Federal University, 236029 Kaliningrad, Russia.

A modern trend in traumatology, orthopedics, and implantology is the development of materials and coatings with an amorphous-crystalline structure that exhibits excellent biocopatibility. The structure and physico-chemical and biological properties of calcium phosphate (CaP) coatings deposited on Ti plates using the micro-arc oxidation (MAO) method under different voltages (200, 250, and 300 V) were studied. Amorphous, nanocrystalline, and microcrystalline statesof CaHPO and β-CaPO were observed in the coatings using TEM and XRD. Read More

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Therapeutic benefits of recombinant alpha1-antitrypsin IgG1 Fc-fusion protein in experimental emphysema.

Respir Res 2021 Jul 16;22(1):207. Epub 2021 Jul 16.

Division of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, USA.

Background: Alpha-1 antitrypsin (AAT) is a major serine protease inhibitor. AAT deficiency (AATD) is a genetic disorder characterized by early-onset severe emphysema. In well-selected AATD patients, therapy with plasma-derived AAT (pAAT), "augmentation therapy", provides modest clinical improvement but is perceived as cumbersome with weekly intravenous infusions. Read More

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Single-crown restorations supported by short implants (6 mm) compared with standard-length implants (13 mm) in conjunction with maxillary sinus floor augmentation: a randomized, controlled clinical trial.

Int J Implant Dent 2021 Jul 16;7(1):66. Epub 2021 Jul 16.

Department of Oral and Maxillofacial Surgery, Aalborg University Hospital, Aalborg, Denmark.

Background: The purpose of the present study was to test the H0-hypothesis of no difference in the clinical and radiographical treatment outcome of single-crown restorations supported by short implants compared with standard length implants in conjunction with maxillary sinus floor augmentation (MSFA) after 1 year of functional implant loading. Forty patients with partial edentulism in the posterior part of the maxilla were randomly allocated to treatment involving single-crown restorations supported by short implants or standard length implants in conjunction with MSFA. Clinical and radiographical evaluation were used to assess survival of suprastructures and implants, peri-implant marginal bone loss (PIMBL), biological, and mechanical complications. Read More

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Augmentation Index Predicts the Sweat Volume in Young Runners.

J Sports Sci Med 2021 Sep 25;20(3):448-456. Epub 2021 May 25.

Cardiovascular Division, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan.

Sweating during exercise is regulated by objective parameters, body weight, and endothelial function, among other factors. However, the relationship between vascular arterial stiffness and sweat volume in young adults remains unclear. This study aimed to identify hemodynamic parameters before exercise that can predict sweat volume during exercise, and post-exercise parameters that can be predicted by the sweat volume. Read More

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September 2021

The Low Window Technique: Comparison between Manual and CAD/CAM-guided Design.

J Contemp Dent Pract 2021 Apr 1;22(4):400-405. Epub 2021 Apr 1.

Department of Cariology and Comprehensive Care, New York University College of Dentistry, New York, United States.

Aim: The aim of this bench study was to provide quantitative data addressing the difference between the manual low window design and the corresponding computer-aided design and computer-aided manufacturing (CAD/CAM)-guided design.

Materials And Methods: Five cone-beam computed tomography (CBCT) scans of as many patients (two males and three females, age range: 61-78 years) with partially edentulous maxilla to be rehabilitated through sinus augmentation, one- or two-step implant placement, and implant-supported prostheses were used to 3D-print the corresponding five maxillary stereolithographic models. Five independent highly skilled maxillofacial surgeons, who were provided with the patients' orthopantomographs, drew on the models the access windows for sinus augmentation according to the "high" (standard) and the low window design both by free-hand and using a surgical guide prepared by computer-guided design. Read More

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Importance of Preserved Tricuspid Valve Function for Effective Soft Robotic Augmentation of the Right Ventricle in Cases of Elevated Pulmonary Artery Pressure.

Cardiovasc Eng Technol 2021 Jul 14. Epub 2021 Jul 14.

Department of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.

Purpose: In clinical practice, many patients with right heart failure (RHF) have elevated pulmonary artery pressures and increased afterload on the right ventricle (RV). In this study, we evaluated the feasibility of RV augmentation using a soft robotic right ventricular assist device (SRVAD), in cases of increased RV afterload.

Methods: In nine Yorkshire swine of 65-80 kg, a pulmonary artery band was placed to cause RHF and maintained in place to simulate an ongoing elevated afterload on the RV. Read More

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Deep transfer learning and data augmentation improve glucose levels prediction in type 2 diabetes patients.

NPJ Digit Med 2021 Jul 14;4(1):109. Epub 2021 Jul 14.

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.

Accurate prediction of blood glucose variations in type 2 diabetes (T2D) will facilitate better glycemic control and decrease the occurrence of hypoglycemic episodes as well as the morbidity and mortality associated with T2D, hence increasing the quality of life of patients. Owing to the complexity of the blood glucose dynamics, it is difficult to design accurate predictive models in every circumstance, i.e. Read More

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Acute Primary Repair of the Anterior Cruciate Ligament With Anterolateral Ligament Augmentation.

Arthrosc Tech 2021 Jun 24;10(6):e1633-e1639. Epub 2021 May 24.

Department of Orthopaedic Surgery, S. Andrea Hospital, University of Rome "La Sapienza, Rome, Italy.

Acute injuries of the anterior cruciate ligament are often associated with concurrent injuries to the structures of the anterolateral complex, specifically the anterolateral ligament. Some injury patterns of the anterior cruciate ligament involve tearing of the majority of the ligament from the femoral origin, leaving a large, viable ligament remnant. In these patients, a repair of the anterior cruciate ligament back to the femoral origin can be undertaken. Read More

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Hip Labral Reconstruction with Capsular Autograft Augmentation.

Arthrosc Tech 2021 Jun 17;10(6):e1547-e1551. Epub 2021 May 17.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, U.S.A.

Multiple treatment options are available for patients presenting with a torn or deficient acetabular labrum. Biomechanical studies have demonstrated that the acetabular labrum may play a role in decreasing the risk of osteoarthritis and in maintaining long-term hip kinematics and stability. As such, repair or reconstruction of the labrum is often preferred over resection or debridement. Read More

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Association of Circulating Extracellular Matrix Components with Central Hemodynamics and Arterial Distensibility of Peripheral Arteries.

J Vasc Res 2021 Jul 12:1-9. Epub 2021 Jul 12.

Laboratory of Functional Reserves of an Organism, Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russian Federation.

Background: In addition to neuronal and endothelial regulators of vascular tone, the passive mechanical properties of arteries, determined by the molecular structure of extracellular matrices, are the principle modulators of vascular distensibility. Specifically, the association between collagen type IV (Col IV), a constituent of basement membrane, and arterial compliance remains unclear.

Methods: In 31 healthy adult men, radial applanation tonometry and pulse wave analysis were used to assess aortic augmentation index (AIx), aortic-to-radial pulse pressure amplification (PPAmpl), and time to reflection wave. Read More

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Comparison Of Endoscopic Transaxillary And Peri-areolar Approaches In Breast Augmentation With Smooth Implants.

Aesthetic Plast Surg 2021 Jul 12. Epub 2021 Jul 12.

Department of Maxillofacial - Plastic - Aesthetic Surgery, Viet-Duc University Hospital, 40 Trang thi, Hanoi, Vietnam.

Introduction: The most common surgical approaches for breast augmentation in Asia have traditionally been peri-areolar and transaxillary. In recent years, transaxillary approach has become increasingly popular with the use of endoscopic methods, which result in safer and better outcomes. In the literature, there are no comparison studies of endoscopic transaxillary and peri-areolar approaches. Read More

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Nutrient limitation of plant reproduction in a tropical moist forest.

Ecology 2021 Jul 10:e03469. Epub 2021 Jul 10.

Smithsonian Tropical Research Institute, Apartado 0843-03092, Balboa, Panama.

Nutrient addition experiments indicate that nitrogen and phosphorus limit plant processes in many tropical forests. However, the long-term consequences for forest structure and species composition remain unexplored. We are positioned to evaluate potential long-term consequences of nutrient addition in central Panama where we have maintained a factorial nitrogen-phosphorus-potassium fertilization experiment for 21 years and an independent study quantified the species-specific nutrient requirements of 550 local tree species. Read More

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Comparative Analyses of Inflammatory Response and Tissue Integration of 14 Hyaluronic Acid-Based Fillers in Mini Pigs.

Clin Cosmet Investig Dermatol 2021 2;14:765-778. Epub 2021 Jul 2.

Gwanggyo R&D Center, Medytox Inc, Suwon-si, Gyeonggi-do, Republic of Korea.

Purpose: Hyaluronic acid (HA)-based dermal fillers have been approved for various clinical indications, both cosmetic and medical. Previous studies that have assessed the performance of HA dermal fillers have primarily focused on evaluating filler durability, and only a few have studied their distribution within the tissues. The present study aimed to compare tissue integration of various types of HA dermal fillers having different clinical indications and varying injection depths. Read More

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Intra-day variation in daily outdoor walking speed among community-dwelling older adults.

BMC Geriatr 2021 Jul 8;21(1):417. Epub 2021 Jul 8.

Towa Hospital, Tokyo, Japan.

Background: Walking speed is an important measure associated with health outcomes in older individuals, such as dependency and death. This study aimed to examine whether the walking speed of community-dwelling older adults varies between time periods within a day, as measured outdoors in daily life. We aimed to determine the types of walking speed variations and examine the factors associated with them. Read More

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