J Vasc Res 2021 Jul 12:1-9. Epub 2021 Jul 12.
Laboratory of Functional Reserves of an Organism, Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russian Federation.
Background: In addition to neuronal and endothelial regulators of vascular tone, the passive mechanical properties of arteries, determined by the molecular structure of extracellular matrices, are the principle modulators of vascular distensibility. Specifically, the association between collagen type IV (Col IV), a constituent of basement membrane, and arterial compliance remains unclear.
Methods: In 31 healthy adult men, radial applanation tonometry and pulse wave analysis were used to assess aortic augmentation index (AIx), aortic-to-radial pulse pressure amplification (PPAmpl), and time to reflection wave. Read More