39,672 results match your criteria assisted reproductive


Nomogram to predict an endometrial thickness above 7.5 mm in the frozen embryo transfer cycle of women with a thin endometrium.

Reprod Biomed Online 2021 Nov 10. Epub 2021 Nov 10.

Reproductive Hospital Affiliated to Shandong University, Jinan Shandong 250001, China; Centre for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan Shandong 250012, China; National Research Centre for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan Shandong 250012, China.

Research Question: Which characteristics of patients with a thin endometrium (endometrial thickness [EMT] ≤7.5 mm on human chorionic gonadotrophin [HCG] trigger day) suggest the possibility of an EMT >7.5 mm in the subsequent frozen cycle?

Design: Data were collected from the university-affiliated Centre for Reproductive Medicine between January 2013 and September 2019. Read More

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November 2021

Maternal advanced age, single parenthood, and ART increase the risk of child morbidity up to five years of age.

BMC Pediatr 2022 Jan 14;22(1):39. Epub 2022 Jan 14.

Department of Obstetrics and Gynecology, and Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.

Background: Advanced maternal age, single status and use of assisted reproductive technology (ART) are increasing in mothers in high-income countries, and all are known risk factors for negative obstetric outcomes. Less is known about their long-term consequences for childhood morbidity. Thus, the aim of this study was to investigate morbidity up to five years of age, in the children of older, single, and/or ART-treated mothers. Read More

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January 2022

LEGAL BASIS FOR THE USE OF ASSISTED REPRODUCTIVE TECHNOLOGIES: A COMPARATIVE ANALYSIS OF THE LEGISLATION OF UKRAINE AND EUROPEAN STATES.

Wiad Lek 2021 ;74(11 cz 2):3021-3024

UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE.

Objective: The aim: Conduct a comparative legal analysis of the legislation of Ukraine and other countries on the use of assisted reproductive technologies (hereinafter - ART).

Patients And Methods: Materials and methods: The study used an interdisciplinary approach to the analysis of the problem of assisted reproductive technologies. This approach includes dialectical, comparative law, statistical and systemic methods. Read More

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January 2021

PROTECTION OF THE RIGHTS OF CHILDREN BORN BY SURROGATE MOTHERS DURING THE COVID-19 PANDEMIC.

Wiad Lek 2021 ;74(11 cz 2):2999-3003

YAROSLAV MUDRYI NATIONAL LAW UNIVERSITY, KHARKIV, UKRAINE.

Objective: The aim: Analyze the practice of resolving the problems of protecting the rights of children born to surrogate mothers in the context of the COVID-19 pandemic.

Patients And Methods: Materials and methods: In carrying out the study, an interdisciplinary approach was applied to the analysis of the problem of protecting the rights of children born to surrogate mothers in the context of the COVID-19 pandemic. This approach includes dialectical, comparative-legal, statistical, and systemic methods. Read More

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January 2021

Artificial intelligence in the embryology laboratory: a review.

Reprod Biomed Online 2021 Nov 12. Epub 2021 Nov 12.

Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston MA, USA. Electronic address:

The goal of an IVF cycle is a healthy live-born baby. Despite the many advances in the field of assisted reproductive technologies, accurately predicting the outcome of an IVF cycle has yet to be achieved. One reason for this is the method of selecting an embryo for transfer. Read More

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November 2021

Contract Remedies Need Not Undercompensate Aspiring Parents When Cryopreserved Reproductive Material Is Lost or Destroyed: Recovery of Consequential Damages for Emotional Disturbance When Breach of Contract Results in the Lost Opportunity to Become Pregnant with One's Own Biological Child.

Authors:
Joseph M Hnylka

J Law Health 2021 ;35(1):99-145

The Center for Disease Control and Prevention (CDC) has reported that the use of assisted reproductive technology (ART) has doubled over the past decade. In vitro fertilization (IVF) is the most prevalent form of ART. During IVF, a woman's eggs are extracted, fertilized in a laboratory setting, and then implanted in the uterus. Read More

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January 2021

Optimal individualization of patient-oriented ovarian stimulation in Japanese assisted reproductive technology clinics, a review for unique setting with advanced-age patients.

J Obstet Gynaecol Res 2022 Jan 13. Epub 2022 Jan 13.

Department of Obstetrics and Gynecology, Saitama Medical University, Saitama, Japan.

Ovarian stimulation is a key issue in assisted reproductive technology (ART) treatment. ART practice in Japan is unique with various types of ovarian stimulation protocols, which may contribute to lower pregnancy rates compared to other countries. This review aims to clarify optimal individualized ovarian stimulation for improving the pregnancy rate per one oocyte retrieval cycle in Japan. Read More

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January 2022

Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1.

Autophagy 2022 Jan 13:1-15. Epub 2022 Jan 13.

Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Ovarian granulosa cells (GCs) proliferate and differentiate along with follicular growth, and this is indispensable for oocyte development and female fertility. Although the role of macroautophagy/autophagy in ovarian function has been reported, its contribution to the regulation of GC characteristics remains elusive. The siRNA-mediated knockdown of two key autophagy-related genes and and the autophagy inhibitor chloroquine were used to interfere with autophagy in GCs. Read More

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January 2022

Conceptualizing aged reproduction: genetic connectedness, son preference and assisted reproduction in North India.

Reprod Biomed Soc Online 2022 Mar 14;14:182-191. Epub 2021 Dec 14.

Department of Liberal Arts, Indian Institute of Technology Hyderabad, Sangareddy, Telangana, India.

In this paper, I explore the narratives on the administration of assisted reproductive technology (ART) treatments amongst ageing men and women who are past their 'reproductive prime'. I use the phrase 'past their reproductive prime' with caution as ART has the capability to resurrect the desire, quest and conception of children amongst these ageing women and men. In rural agrarian Haryana in North India, ART panders to, and provides, potent narratives for perpetuation of the patrilineage for genetic continuity through the male line. Read More

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The making of 'old eggs': the science of reproductive ageing between fertility and anti-ageing technologies.

Authors:
Nolwenn Bühler

Reprod Biomed Soc Online 2022 Mar 23;14:169-181. Epub 2021 Aug 23.

University of Neuchâtel, Switzerland.

This article proposes going back in the history of reproductive medicine to shed light on the role of assisted reproductive technology (ART) in the making of 'old eggs'. Focusing on two key technologies - egg donation and cytoplasmic transfer - both of which contributed significantly to the production of scientific knowledge about reproductive ageing, the article suggests that ART can be analysed as 'in-vivo models' playing a pivotal role in the shift from age as a demographic variable to ageing understood in biological terms. It will shed light on the role of ART in locating age in the eggs and producing a cellular understanding of fertility decline. Read More

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Enthusiasm, concern and ambivalence in the Belgian public's attitude towards in-vitro gametogenesis.

Reprod Biomed Soc Online 2022 Mar 25;14:156-168. Epub 2021 Nov 25.

Department of Philosophy and Moral Sciences, Ghent University, Ghent, Belgium.

Given the controversial nature of research into in-vitro gametogenesis (IVG), this study set out to investigate the current attitudes towards IVG in the general Belgian population in order to anticipate potential future barriers and misunderstandings. A questionnaire was developed and incorporated into a web-based online survey and sent out to Belgians aged ≥ 18 years in September 2018 until a representative sample (by age, gender and region) of 1000 participants was reached. Respondents expressed an overall positive attitude towards IVG and its possible future applications, with the exception of the use of IVG in postmenopausal women. Read More

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The ART clock: Temporal limits to assisted reproduction.

Authors:
Heather Jacobson

Reprod Biomed Soc Online 2022 Mar 25;14:144-155. Epub 2021 Nov 25.

Department of Sociology and Anthropology, The University of Texas at Arlington, Arlington, TX, USA.

Conceptualizations of the 'biological clock' in popular imaginary in the USA centre on the temporal limits of fertility, with assisted reproductive technology (ART) an increasingly proposed answer to these constraints (at least in the public imaginary). In this study, I analyse how surrogates in the USA understand their own bioavailability for others' reproductive needs in the commercial ART market vis-à-vis their own reproductive trajectories. Based on interview data with gestational surrogates, I propose a new concept of the 'ART clock' to capture how time shapes the experiences of reproductive workers in the US fertility clinic. Read More

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Novel exon mutation in SYCE1 gene is associated with non-obstructive azoospermia.

J Cell Mol Med 2022 Jan 12. Epub 2022 Jan 12.

Reproductive Medicine Center, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital of Henan University, Zhengzhou, China.

Non-obstructive azoospermia (NOA) is a common cause of male infertility, and genetic problems, such as chromosomal abnormalities and gene mutations, are important causes of NOA. Our centre received a case of NOA, in which no mature sperm was found during microdissection testicular sperm extraction. A postoperative pathological examination revealed that testicular spermatogenesis was blocked. Read More

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January 2022

Introduction of an efficient method for placenta decellularization with high potential to preserve ultrastructure and support cell attachment.

Artif Organs 2022 Jan 12. Epub 2022 Jan 12.

Department of Molecular Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.

The placenta, as a large discarded tissue and rich in extracellular matrix (ECM), is an excellent candidate for biological scaffolds in reconstructive medicine. Considering the importance of ECM structure in cell fate, the aim of this study was to achieve human placenta decellularization protocol that preserve the structure of scaffolds. Thus, human placenta was decellularized by four protocols and decellularization efficacy was compared by hematoxylin and eosin (H&E), 4',6-diamidino-2-phenylindole (DAPI) staining, and DNA measurement. Read More

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January 2022

The function of Nucleoporin 37 on mouse oocyte maturation and preimplantation embryo development.

J Assist Reprod Genet 2022 Jan 13. Epub 2022 Jan 13.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.

Purpose: Nucleoporin 37 (NUP37) has been reported to activate the YAP-TEAD signaling, which is crucial for early embryo development. However, whether NUP37 is involved in oocyte meiosis and embryo development remains largely unknown. The study aimed to clarify the function of Nup37 in oocyte maturation and early embryo development, and to explore the mechanism. Read More

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January 2022

Transcriptome analysis of eutopic endometrium in adenomyosis after GnRH agonist treatment.

Reprod Biol Endocrinol 2022 Jan 12;20(1):13. Epub 2022 Jan 12.

Reproductive Medicine Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, People's Republic of China.

Background: Adenomyosis is a chronic gynecological disease characterized by invasion of the uterine endometrium into the muscle layer. In assisted reproductive technology (ART), gonadotropin-releasing hormone agonist (GnRHa) is often used to improve pregnancy rates in patients with adenomyosis, but the underlying mechanisms are poorly understood.

Methods: Eutopic endometrial specimens were collected from patients with adenomyosis before and after GnRHa treatment in the midsecretory phase. Read More

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January 2022

Electrophysiology of Human Gametes: A Systematic Review.

World J Mens Health 2022 Jan 2. Epub 2022 Jan 2.

Department of Physiology, Faculty of Medicine, Biosciences and Nursing, MAHSA University, Jenjarom, Selangor, Malaysia.

Purpose: Oocytes and spermatozoa are electrogenic cells with the ability to respond to electrical stimuli and modulate their electrical properties accordingly. Determination of the ionic events during the gamete maturation helps to design suitable culture media for gametes in assisted reproductive technology (ART). The present systematic review focuses on the electrophysiology of human gametes during different stages of maturation and also during fertilization. Read More

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January 2022

Sleep quality is associated with the weight of newborns after in vitro fertilization (IVF)/intra-cytoplasmic sperm injection (ICSI).

Sleep Breath 2022 Jan 12. Epub 2022 Jan 12.

Reproductive Genetic Center, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, 26th Daoqian Road, Suzhou, 215000, China.

Background: Sleep disorders are thought to be common in women with in vitro fertilization and embryo transfer (IVF-ET) conception. Although a few studies have investigated the association between maternal sleep quality and infant birth weight, it is unclear to what extent birth weight is associated with sleep quality during pregnancy among these women. Therefore, we conducted a cohort study to assess sleep quality among women receiving IVF-ET during the subsequent pregnancy and investigated the association of self-report sleep quality on infant birth weight. Read More

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January 2022

Fetal neurosonography at 31-35 weeks reveals altered cortical development in pre-eclampsia with and without small-for-gestational-age fetus.

Ultrasound Obstet Gynecol 2022 Jan 11. Epub 2022 Jan 11.

BCNatal | Fetal Medicine Research Center (Hospital Clínic and Hospital Sant Joan de Déu), University of Barcelona, Barcelona, Spain.

Objectives: The aim of this study was to explore the pattern of fetal cortical development in pregnancies complicated by preeclampsia with and without fetal growth restriction compared to uncomplicated pregnancies.

Methods: Prospective observational study including pregnancies complicated by normotensive fetal growth restriction (birthweight <10 centile) (n=77), preeclampsia with a normally grown fetus (n=76), preeclampsia with fetal growth restriction (n=67), and 128 uncomplicated pregnancies matched by gestational age at ultrasound. Detailed neurosonography with transabdominal and transvaginal approach was performed at 31-35 weeks including the measurement of insula, Sylvian fissure and parieto-occipital, cingulate and calcarine sulci. Read More

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January 2022

Cardiovascular function in 8- to 9-year-old singletons born after ART with frozen and fresh embryo transfer.

Hum Reprod 2022 Jan 7. Epub 2022 Jan 7.

Fertility Department, Copenhagen University Hospital, Rigshospitalet, Denmark, Copenhagen.

Study Question: Do 8- to 9-year-old singletons conceived after frozen embryo transfer (FET) or fresh embryo transfer (Fresh-ET) have increased arterial stiffness compared to naturally conceived (NC) children?

Summary Answer: The process of FET or Fresh-ET is not associated with altered cardiovascular function in 8- to 9-year-old singletons, including arterial stiffness, as compared to NC children.

What Is Known Already: ART has been suggested to influence cardiovascular risk factors (i.e. Read More

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January 2022

Combined analysis of human chorionic gonadotrophin concentrations at different time points after frozen-thawed blastocyst transfer can improve our ability to predict the pregnancy outcomes of single gestations.

J Obstet Gynaecol 2022 Jan 11:1-7. Epub 2022 Jan 11.

Centre of Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University, Third Hospital, Beijing, China.

In this study, we conducted a retrospective single-centre study of 1664 singleton pregnancies derived from frozen-thawed blastocyst transfer between January 2017 and December 2018. Analysis showed that there were 596 early pregnancy losses and 1068 ongoing pregnancies. We compared serum HCG (human chorionic gonadotophin) concentrations on days 12, 14, 19, and 21, between the pregnancy loss group and the ongoing pregnancy group. Read More

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January 2022

Prevalence and determinants of self-reported anxiety and stress among women with abortion-related complications admitted to health facilities in Eastern and Southern Africa: A cross-sectional survey.

Int J Gynaecol Obstet 2022 Jan 11. Epub 2022 Jan 11.

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.

Objective: To estimate the prevalence of women who were admitted to health facilities with abortion-related complications who reported feeling anxious/stressed during their stay, and to identify sociodemographic, facility, and abortion-related characteristics associated with self-reported experience of anxiety/stress.

Methods: We used data from four countries in Eastern and Southern Africa (Kenya, Malawi, Mozambique, and Uganda) collected from 2017-2018 as part of the World Health Organization (WHO) Multi-Country Survey on Abortion-related morbidity (MCS-A). Information was extracted from women's medical records and their participation in audio computer-assisted self-interviews (ACASI). Read More

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January 2022

Comparison of day 5 blastocyst with day 6 blastocyst: Evidence from NGS-based PGT-A results.

J Assist Reprod Genet 2022 Jan 10. Epub 2022 Jan 10.

Center for Reproductive Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200135, China.

Purpose: Aneuploidy is one genetic factor leading to the failure of embryo implantation. This study aimed to investigate the relationship between the day of embryo blastulation and the ploidy status of embryo, to aid in selecting embryos with the most likelihood of of being euploid in a noninvasive way.

Methods: This retrospective study recruited women undergoing preimplantation genetic testing (PGT) for aneuploidy (PGT-A) with trophectoderm biopsy from January 2019 to December 2020. Read More

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January 2022

Progressing Ultragreen, Energy-Efficient Biobased Depolymerization of Poly(ethylene terephthalate) via Microwave-Assisted Green Deep Eutectic Solvent and Enzymatic Treatment.

Polymers (Basel) 2021 Dec 29;14(1). Epub 2021 Dec 29.

Materials Research Institute, Technological University of the Shannon: Midlands Midwest, N37 HD68 Athlone, Ireland.

Effective interfacing of energy-efficient and biobased technologies presents an all-green route to achieving continuous circular production, utilization, and reproduction of plastics. Here, we show combined ultragreen chemical and biocatalytic depolymerization of polyethylene terephthalate (PET) using deep eutectic solvent (DES)-based low-energy microwave (MW) treatment followed by enzymatic hydrolysis. DESs are emerging as attractive sustainable catalysts due to their low toxicity, biodegradability, and unique biological compatibility. Read More

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December 2021

Boar Semen Contamination: Identification of Gram-Negative Bacteria and Antimicrobial Resistance Profile.

Animals (Basel) 2021 Dec 27;12(1). Epub 2021 Dec 27.

Infectious Diseases Department, Faculty of Veterinary Medicine, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, 119 Aradului Street Timisoara, Timis County, 300645 Timisoara, Romania.

Bacterial contamination of boar semen occurs with some frequency in artificial insemination centers and may have a negative effect on the quality of the semen as well as on the sows' reproductive capacity. Normally, the source of bacterial contamination in pig seminal doses is the own boar. However, distilled water or laboratory equipment used to elaborate the seminal doses can be an important source of bacterial contamination. Read More

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December 2021

Correlations among Ultrasonographic, Physicochemical and Sensory Characteristics of Pectoralis Major Muscles in Turkeys Reared in a Sustainable Farming System.

Animals (Basel) 2021 Dec 21;12(1). Epub 2021 Dec 21.

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Rd., Guelph, ON N1G 2W1, Canada.

This study set out to examine associations among echotextural, physicochemical and sensory attributes of the pectoralis major muscles in 17-week-old organic turkeys (B.U.T. Read More

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December 2021

Advances in Thermal Image Analysis for the Detection of Pregnancy in Horses Using Infrared Thermography.

Sensors (Basel) 2021 Dec 28;22(1). Epub 2021 Dec 28.

Department of Animal Breeding, Institute of Animal Science, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.

Infrared thermography (IRT) was applied as a potentially useful tool in the detection of pregnancy in equids, especially native or wildlife. IRT measures heat emission from the body surface, which increases with the progression of pregnancy as blood flow and metabolic activity in the uterine and fetal tissues increase. Conventional IRT imaging is promising; however, with specific limitations considered, this study aimed to develop novel digital processing methods for thermal images of pregnant mares to detect pregnancy earlier with higher accuracy. Read More

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December 2021

The Endometrial Microbiome and Its Impact on Human Conception.

Int J Mol Sci 2022 Jan 1;23(1). Epub 2022 Jan 1.

Igenomix Foundation/INCLIVA Biomedical Research Institute, Narcis Monturiol Estarriol 11B, 46980 Paterna, Spain.

Changes in the female genital tract microbiome are consistently correlated to gynecological and obstetrical pathologies, and tract dysbiosis can impact reproductive outcomes during fertility treatment. Nonetheless, a consensus regarding the physiological microbiome core inside the uterine cavity has not been reached due to a myriad of study limitations, such as sample size and experimental design variations, and the influence of endometrial bacterial communities on human reproduction remains debated. Understanding the healthy endometrial microbiota and how changes in its composition affect fertility would potentially allow personalized treatment through microbiome management during assisted reproductive therapies, ultimately leading to improvement of clinical outcomes. Read More

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January 2022

The Role of Genital Tract Microbiome in Fertility: A Systematic Review.

Int J Mol Sci 2021 Dec 24;23(1). Epub 2021 Dec 24.

Department of Obstetrics and Gynecology, University of Messina, 98122 Messina, Italy.

The human microbiome plays a crucial role in determining the health status of every human being, and the microbiome of the genital tract can affect the fertility potential before and during assisted reproductive treatments (ARTs). This review aims to identify and appraise studies investigating the correlation of genital microbiome to infertility. Publications up to February 2021 were identified by searching the electronic databases PubMed/MEDLINE, Scopus and Embase and bibliographies. Read More

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December 2021