70,295 results match your criteria assess severity

QABF - Polish adaptation and validation of the tool for assessing the functions of challenging behaviors.

Res Dev Disabil 2021 Jul 20;116:104032. Epub 2021 Jul 20.

Pedagogical University of Krakow, Institute of Special Needs Education, R. Ingardena 4 St., 30-060, Cracow, Poland. Electronic address:

Background: Autism spectrum disorders are a diagnostic unit predisposing the occurrence of challenging behaviors. Depending on their frequency and severity, behavioral problems may significantly limit the developmental possibilities of people with ASD, and also significantly affect family life and the therapeutic process. Aggressive, self-injury, destructive or stereotypic behaviors require intervention based on individualized support, the basis of which should be a functional assessment. Read More

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Improving severity scoring of food-induced allergic reactions: a global "Best-Worst Scaling" exercise.

J Allergy Clin Immunol Pract 2021 Jul 19. Epub 2021 Jul 19.

National Heart & Lung Institute, Imperial College London, London, UK;. Electronic address:

Background: There is no current consensus on assigning severity to food-induced allergic reactions, for example to assess the efficacy of allergen immunotherapy. Existing severity scores lack the capability to discriminate between non-anaphylaxis reactions of different severities. Attempts are ongoing to develop a more discriminatory score, which should ideally be data-driven and validated in multiple cohorts. Read More

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The interactions between childhood adversities and recent stress were associated with early-adulthood depression among Chinese undergraduate students.

Depress Anxiety 2021 Jul 22. Epub 2021 Jul 22.

Mental Health Center and Psychiatric Laboratory, the State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Background: It is widely acknowledged that childhood adversities (CAs) and recent stress are potential risk factors for adult depression. However, the mechanism(s) by which interactions of CAs with recent stress affect adult depression remain unclear.

Aims: To investigate the predictive association of the interaction among CAs and recent stress with early-adult depression. Read More

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Predictors of COVID-19 vaccine intentions in the United States: the role of psychosocial health constructs and demographic factors.

Transl Behav Med 2021 Jul 22. Epub 2021 Jul 22.

Department of Psychology, Emmanuel College, Boston, MA, USA.

Background: On December 21, 2020, a study was conducted to investigate a range of psychosocial health constructs and demographic variables potentially associated with intentions toward accepting or forgoing the coronavirus (COVID-19) vaccine.

Purpose: The goal of the study was to identify predictors of forgoing COVID-19 vaccination at the time of the initial rollout.

Methods: A cross-sectional, representative online survey of 350 U. Read More

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Time-trends and predictors of interhospital transfers and 30-day rehospitalizations after acute coronary syndrome from 2000-2015.

PLoS One 2021 22;16(7):e0255134. Epub 2021 Jul 22.

Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS) and Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Porto, Portugal.

Aims: Assess trends and factors associated with interhospital transfers (IHT) and 30-day acute coronary syndrome (ACS) rehospitalizations in a national administrative database of patients admitted with an ACS between 2000-2015.

Methods And Results: Cohort study of patients hospitalized with ACS from 2000 to 2015, using a validated linkage algorithm to identify and link patient-level sequential hospitalizations occurring within 30 days from first admission (considering all hospitalizations within the 30-day timeframe as belonging to the same ACS episode of care-ACS-EC). From 212,481 ACS-EC, 42,670 (20. Read More

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Both high and low pre-infection glucose levels associated with increased risk for severe COVID-19: New insights from a population-based study.

PLoS One 2021 22;16(7):e0254847. Epub 2021 Jul 22.

Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Importance: Patients with diabetes are known to be at increased risk for infections including severe coronavirus disease 2019 (COVID-19) but the relationship between COVID-19 severity and specific pre-infection glucose levels is not known.

Objective: To assess the differential effects of pre-infection glucose levels on the risk for severe COVID-19 amongst patients with and without diabetes.

Design: Population based historical cohort study. Read More

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Repeated extreme heatwaves result in higher leaf thermal tolerances and greater safety margins.

New Phytol 2021 Jul 22. Epub 2021 Jul 22.

Hawkesbury Institute for the Environment, Western Sydney University, Richmond, NSW, 2753, Australia.

• The frequency and severity of heatwave events are increasing, exposing species to conditions beyond their physiological limits. Species respond to heatwaves in different ways, however it remains unclear if plants have the adaptive capacity to successfully respond to hotter and more frequent heatwaves. • We exposed eight tree populations from two climate regions grown under cool and warm temperatures to repeated heatwave events of moderate (40 ºC) and extreme (46 ºC) severity to assess adaptive capacity to heatwaves. Read More

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Cross-cultural adaptation of the SWAL-QOL and the Sydney Swallow Questionnaire (SSQ) into French-Canadian and preliminary assessment for their use in an oculopharyngeal muscular dystrophy (OPMD) population.

Qual Life Res 2021 Jul 22. Epub 2021 Jul 22.

Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Québec, Canada.

Purpose: Patient-reported outcomes (PRO) assessing dysphagia are an essential component of clinical trials to consider how patients feel and function in response to treatments. The selected PRO needs to be translated in several languages using a systematic process ensuring its validity and equivalence for use in multicenter clinical trials. The main objectives were to translate the SWAL-QOL and the Sydney Swallow Questionnaire (SSQ) into French Canadian (SWAL-QOL-FC and SSQ-FC) and to assess their appropriateness for patients with oculopharyngeal muscular dystrophy (OPMD). Read More

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Fatigue is associated with depression independent of excessive daytime sleepiness in the general population.

Sleep Breath 2021 Jul 22. Epub 2021 Jul 22.

Sleep Disorders Center, Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan, 31151, South Korea.

Purpose: This study aimed to investigate sleep problems and comorbid conditions associated with fatigue in the general population.

Methods: The data were obtained from a nationwide cross-sectional survey conducted in 2018. The Fatigue Severity Scale was used to assess fatigue. Read More

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Assessment of regional water demand for coal-based power plants in India: exploring its regional impact on other cross-sectoral water stress.

Environ Monit Assess 2021 Jul 22;193(8):503. Epub 2021 Jul 22.

The Energy and Resources Institute, New Delhi, India.

Water use in coal power generation is one of the key points to highlight for the countries like India because country electricity demand increases rapidly which led to increase in water demand. The coal power sector in India will remain to be the dominant source of electricity generation until 2040 and will require a regular water supply, which is already in a stressful condition. This work focuses on the regional assessment of water withdrawal and consumption of the coal power sector at three broad stages includes fuel extraction, fuel preparation, and power generation. Read More

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Interleukin19 gene polymorphism and its serum level in acne vulgaris patients.

J Immunoassay Immunochem 2021 Jul 22. Epub 2021 Jul 22.

Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.

Numerous cytokines are involved in acne vulgaris pathogenesis, though few studies correlate interleukin IL-19 to acne vulgaris. So this study aimed to assess the IL-19 (rs 2243191) gene polymorphism and its serum level in acne vulgaris. This case-control study involved 90 acne vulgaris cases and 90 age- and sex-matched controls. Read More

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Laser treatment of pilonidal disease: a systematic review.

Lasers Med Sci 2021 Jul 22. Epub 2021 Jul 22.

Department of Surgery, University Hospital Centre Zagreb, Kispaticeva 12, 10 000, Zagreb, Croatia.

Pilonidal disease (PD) is a common condition, and there is still an ongoing debate on ideal management that should be minimally invasive, safe, and efficient. The use of radially emitting laser in the treatment of chronic PD is a novel minimally invasive technique, and initial studies with a small number of patients showed promising results. This study aimed to assess the efficacy and safety of chronic PD treatment with a laser using a systematic review of the published literature. Read More

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Patterns of airway obstruction of non-acquired origin in children with and without major congenital anomalies.

Eur J Pediatr 2021 Jul 21. Epub 2021 Jul 21.

Department of Otorhinolaryngology Head and Neck Surgery Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.

Major congenital anomalies are known to play a role in the management and prognosis of airway obstruction. Most studies assess acquired forms of airway obstruction. Data on congenital or otherwise non-acquired forms of airway obstruction is sparse. Read More

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Using Psychedelics With Therapeutic Intent Is Associated With Lower Shame and Complex Trauma Symptoms in Adults With Histories of Child Maltreatment.

Chronic Stress (Thousand Oaks) 2021 Jan-Dec;5:24705470211029881. Epub 2021 Jul 11.

Department of Psychology, The New School for Social Research, New York, NY, USA.

Background: Child maltreatment negatively affects the formation of internal schemata of self and other during development, leading to negative adaptations in self-concept and social cognition. Clinical reports suggest the efficacy of psychedelics in treating the psychopathological sequelae of child maltreatment. Altering maladaptive schemata of self and other implicated in negative self-concept and impaired social cognition may be a central mechanism for reducing posttraumatic stress symptoms. Read More

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The validity and reliability of benevolent childhood experiences scale in Chinese community adults.

Eur J Psychotraumatol 2021 12;12(1):1945747. Epub 2021 Jul 12.

School of Psychology, Jiangxi Normal University, Nanchang, P.R.China.

Background: Several studies have indicated that positive childhood experiences (PCEs) might have important protective effects on adulthood mental health. However, the instruments to assess PCEs are scarce.

Objective: In this study, we assessed the validity and reliability of the Benevolent Childhood Experiences (BCEs) scale, a new instrument of PCEs, in a large sample of Chinese adults. Read More

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Clinical outcomes of maitland mobilization in patients with Myofascial Chronic Neck Pain: A randomized controlled trial.

Pak J Med Sci 2021 Jul-Aug;37(4):1172-1178

Dr. Nadia Saleem, MS (Rehab), Assistant Professor, Bakhtawar Amin College of Rehabilitation Sciences, Multan Pakistan.

Background And Objective: Myofascial neck pain is a common musculoskeletal problem caused by presence of trigger points and local and referred pain patterns. Chronic neck pain is responsible for the involvement of joints, ligaments, fascia and connective tissue as well. The objective of this study was to assess the effect of Maitland mobilization in patients with myofascial chronic neck pain. Read More

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January 2021

Outlook of Cassava Brown Streak Disease Assessment: Perspectives of the Screening Methods of Breeders and Pathologists.

Front Plant Sci 2021 5;12:648436. Epub 2021 Jul 5.

Root Crops Program, National Crops Resources Research Institute (NaCRRI), Kampala, Uganda.

Cassava production and productivity in Eastern, Central, and Southern Africa are ravaged by cassava brown streak disease (CBSD), causing yield losses of up to 100% when susceptible varieties are grown. Efforts to develop CBSD-resistant clones are underway. However, the methods for screening CBSD resistance currently vary between breeders and pathologists, with the limited empirical data to support their choices. Read More

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Uterine Artery Embolization with Small-Sized Particles for the Treatment of Symptomatic Adenomyosis: A 42-Month Clinical Follow-Up.

Int J Gen Med 2021 15;14:3575-3581. Epub 2021 Jul 15.

Medical School of Chinese PLA, Beijing, 100853, People's Republic of China.

Purpose: To assess the long-term outcome of performing uterine artery embolization (UAE) using small particles in women with symptomatic adenomyosis (AD).

Methods: Twenty-seven consecutive women (median age 42 years, range 29-53 years) with AD, in eight cases AD combined with fibroids, who underwent UAE between February 2015 and January 2019, were retrospectively analyzed. The embolization was performed using small-sized polyvinyl alcohol particles (100 μm and 300 μm). Read More

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The development of a contextually appropriate measure of psychological distress in Sierra Leone.

BMC Psychol 2021 Jul 21;9(1):108. Epub 2021 Jul 21.

NIHR Global Health Research Unit On Health in Situations of Fragility, Institute for Global Health and Development, Queen Margaret University, Edinburgh, UK.

Background: Studies of psychological distress in Sierra Leone have typically used measures which were developed for use in other contexts, and which often have not been adapted or validated for use in Sierra Leone. This has resulted in a lack of reliable information about the patterns of psychological distress within the population, which is a barrier to the development of effective and appropriate mental health services. The aim of the study was to develop a locally-appropriate measure of psychological distress for Sierra Leone. Read More

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Paradoxical low severity of COVID-19 in Prader-Willi syndrome: data from a French survey on 647 patients.

Orphanet J Rare Dis 2021 07 21;16(1):325. Epub 2021 Jul 21.

Assistance Publique-Hôpitaux de Paris, Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d'obésité avec troubles du comportement alimentaire), Hôpital Marin d'Hendaye, ENDO-ERN (European Reference Network on Rare Endocrine Conditions), Hendaye, France.

Background: Patients with Prader-Willi syndrome (PWS) often have comorbidities, especially obesity, that may constitute a risk factor for severe forms of COVID-19. We aimed to assess prevalence and medical course of SARS-CoV-2 infection in children and adults with PWS. From November 2020 to January 2021, we performed a detailed medical survey on 342 adults and 305 children with PWS followed in the French reference center. Read More

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Short term physician visits and medication prescriptions for allergic disease associated with seasonal tree, grass, and weed pollen exposure across the United States.

Environ Health 2021 Jul 21;20(1):85. Epub 2021 Jul 21.

Department of Emergency Medicine, School of Medicine, University of Washington, Seattle, WA, USA.

Background: While year-round exposure to pollen is linked to a large burden of allergic diseases, location-specific risk information on pollen types and allergy outcomes are limited. We characterize the relationship between acute exposure to tree, grass and weed pollen taxa and two allergy outcomes (allergic rhinitis physician visit and prescription allergy medication fill) across 28 metropolitan statistical areas (MSA) in the United States.

Methods: We obtained daily pollen data from National Allergy Bureau (NAB) monitors at these 28 MSAs for 2008-2015. Read More

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Ecological consequences of Australia's 'Black Summer' bushfires.

Integr Environ Assess Manag 2021 Jul 21. Epub 2021 Jul 21.

School of Life and Environmental Sciences, University of Sydney, NSW, 2006, Australia.

Fire has long been a part of the Australian environment and remains a potent force in shaping the adaptations of species, the dynamics of populations, and the structure of ecological communities. However, the fire regime is changing. Fire seasons are longer, wet vegetation types that do not usually burn are now at risk, and fire intensity and severity are greater than in the recent past. Read More

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Position statement on the role of nurses in therapeutic patient education in atopic dermatitis.

J Eur Acad Dermatol Venereol 2021 Jul 21. Epub 2021 Jul 21.

Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

In chronic skin diseases such as atopic dermatitis (AD), therapeutic failure due to poor patient adherence to treatment is commonly reported. Therapeutic patient education (TPE) is an approach to improve self-management and adherence. Several studies demonstrated that TPE programmes have positive effects on disease management resulting in decreased disease severity and improved quality of life in AD patients. Read More

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Diffusion MRI reveals tract-specific microstructural correlates of electrophysiological impairments in non-myelopathic and myelopathic spinal cord compression.

Eur J Neurol 2021 Jul 21. Epub 2021 Jul 21.

Central European Institute of Technology, Masaryk University, Brno, Czechia.

Background: Non-myelopathic degenerative cervical spinal cord compression (NMDC) frequently occurs throughout aging and may progress to potentially irreversible degenerative cervical myelopathy (DCM). Whereas standard clinical MRI and electrophysiological measures assess compression severity and neurological dysfunction, respectively, underlying microstructural deficits still have to be established in NMDC and DCM patients. The study aims to establish tract-specific diffusion MRI markers of electrophysiological deficits to predict the progression of asymptomatic NMDC to symptomatic DCM. Read More

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Sleep quality and architecture in COPD: the relationship with lung function abnormalities.

J Bras Pneumol 2021 19;47(3):e20200612. Epub 2021 Jul 19.

. Division of Respiratory & Sleep Medicine, Department of Medicine, Queen's University, Kingston (ON) Canada.

Objective: Impaired respiratory mechanics and gas exchange may contribute to sleep disturbance in patients with COPD. We aimed to assess putative associations of different domains of lung function (airflow limitation, lung volumes, and gas exchange efficiency) with polysomnography (PSG)-derived parameters of sleep quality and architecture in COPD.

Methods: We retrospectively assessed data from COPD 181 patients ≥ 40 years of age who underwent spirometry, plethysmography, and overnight PSG. Read More

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Sleep quality and its association with menopausal and climacteric symptoms.

Rev Bras Enferm 2021 16;74Suppl 2(Suppl 2):e20201150. Epub 2021 Jul 16.

Universidade Federal de São Paulo. São Paulo, São Paulo, Brazil.

Objective: to assess sleep quality in menopausal women and its association with symptoms related to this period.

Method: this is a cross-sectional, analytical and correlational study. Sleep was assessed using the Pittsburgh Sleep Quality Index; and climacteric symptoms, according to the Menopause Rating Scale. Read More

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Diagnostic Accuracy of Clinical Tests Assessing Ligamentous Injury of the Talocrural and Subtalar Joints: A Systematic Review With Meta-Analysis.

Sports Health 2021 Jul 21:19417381211029953. Epub 2021 Jul 21.

School of Health Sciences, Faculty of Life and Health Sciences, Ulster University, Jordanstown Campus, Antrim, UK.

Context: Ankle sprains are the most common acute musculoskeletal injury. Clinical tests represent the first opportunity to assess the sprain's severity, but no systematic review has compared these tests to contemporary reference standards.

Objective: To determine the diagnostic accuracy of clinical tests assessing the talocrural and subtalar joint ligaments after ankle sprain. Read More

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Levetiracetam for Seizure Prophylaxis in Neurocritical Care: A Systematic Review and Meta-analysis.

Neurocrit Care 2021 Jul 20. Epub 2021 Jul 20.

Department of Neurology, New York University Grossman School of Medicine, 150 55th St. Brooklyn, New York, NY, 11220, USA.

Background: Levetiracetam is commonly used for seizure prophylaxis in patients with intracerebral hemorrhage (ICH), traumatic brain injury (TBI), supratentorial neurosurgery, and spontaneous subarachnoid hemorrhage (SAH). However, its efficacy, optimal dosing, and the adverse events associated with levetiracetam prophylaxis remain unclear.

Methods: A systematic search of PubMed, Embase, and Cochrane central register of controlled trials (CENTRAL) database was conducted from January 1, 2000, to October 30, 2020, including articles addressing treatment with levetiracetam for seizure prophylaxis after SAH, ICH, TBI, and supratentorial neurosurgery. Read More

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N-Terminal pro-brain natriuretic peptide (NTproBNP) in patients with symptomatic multiple myeloma: report from a single institution.

Ann Hematol 2021 Jul 21. Epub 2021 Jul 21.

Department of Medical Oncology and Hematology, Tom Baker Cancer Center, 1331 29th St, NW, Calgary, AB, T2N 4N2, Canada.

Elevated levels of serum cardiovascular markers including natriuretic peptides (NPs) such as amino terminal pro-brain natriuretic peptide (NTproBNP) have been associated with disease severity and survival in cancer patients and more recently in multiple myeloma (MM). In the present study, we retrospectively reviewed 87 consecutive symptomatic TEMM (transplant-eligible) and 126 TIMM (transplant-ineligible) patients treated at our institution that did undergo NTproBNP testing from 2017 to 2020. Median age at diagnosis was 59. Read More

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