1,675 results match your criteria aspiration oxygen

Noninvasive Ventilation Use in Pediatric Status Asthmaticus.

J Asthma 2021 Jun 10:1-9. Epub 2021 Jun 10.

Department of Critical Care, New York-Presbyterian Morgan Stanley Children's Hospital.

Noninvasive ventilation (NIV) is sometimes used in refractory pediatric status asthmaticus for its potential benefits of stenting airways and dispersing albuterol. However, its effectiveness in pediatric asthma remains unproven. The usage pattern, outcomes, and safety of NIV in pediatric status asthmaticus are described. Read More

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Predictive power of modified frailty index score for pulmonary complications after major abdominal surgery in the elderly: a single centre prospective cohort study.

Eur Rev Med Pharmacol Sci 2021 May;25(10):3798-3802

Dipartimento di Scienze dell'Emergenza, Anestesiologiche e della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Objective: The primary aim of this prospective cohort study was to evaluate the usefulness of the modified Frailty Index (mFI) score to predict postoperative pulmonary complications (PPCs) in elderly patients undergoing major open abdominal surgery. The secondary purpose was to compare the prediction power of mFI, Ariscat (Assess Respiratory Risk in Surgical Patients in Catalonia), and American Society physical status classification (ASA) scores.

Patients And Methods: After local Ethical Committee approval, 105 patients aged ≥65 years undergoing open major abdominal surgery were enrolled. Read More

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Asphyxia and Neonatal Respiratory Distress Syndrome Are Independent Predictors of the Non-response to Inhaled Nitric Oxide in the Newborns With PPHN.

Front Pediatr 2021 20;9:665830. Epub 2021 May 20.

Neonatology Department, Anhui Provincial Children Hospital, Hefei, China.

Not all the neonates respond with improvement in oxygenation following inhaled nitric oxide treatment (iNO) treatment. The aim of this study was to assess the independent risk factors associated with non-response to iNO during the 2 weeks of postnatal treatment in neonates diagnosed with persistent pulmonary hypertension (PPHN). This retrospective cohort study included all newborns with PPHN who received iNO treatment for more than 24 h. Read More

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Wedge resection on recurrent pneumothorax, failed lung expansion after needle aspiration: A case report.

Int J Surg Case Rep 2021 May 21;83:106000. Epub 2021 May 21.

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Electronic address:

Background: Pneumothorax has several classifications, including based on etiology, location, extent, and degree of collapse as well as by mechanism and type.

Case Presentation: A 61-years-old man with the main complaint of sudden shortness of breath after lifting a birdcage. The complaint worsened, and it was accompanied by nausea, sweating, and decreased vital signs. Read More

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Poppy Intoxication in Infants and Children: Hazards of a Folk Remedy.

J Coll Physicians Surg Pak 2021 May;30(5):576-581

Department of Paediatrics, Mardan Medical Complex, Mardan, Pakistan.

Objective: To study the clinical and laboratory profile in infants and children presented in the tertiary care hospital with poppy intake and to compare the profile between those who survived with those who died.

Study Design:   Observational study. Study Place and Duration: Department Of Paediatrics, Mardan Medical Complex, Mardan, KPK, Pakistan from January 2019 to January 2020. Read More

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Prevention of hemorrhage-induced renal vasoconstriction and hypoxia by angiotensin II type 1 receptor antagonism in pigs.

Am J Physiol Regul Integr Comp Physiol 2021 05 19. Epub 2021 May 19.

Department of Surgical Sciences, Anesthesiology and Intensive Care, Uppsala University, Sweden.

Angiotensin II (AngII) is a potent vasoconstrictor and may reduce renal blood flow (RBF), causing renal hypoxia. Hypotensive hemorrhage elevates plasma AngII levels and is associated with increased risk of acute kidney injury. We hypothesized that AngII antagonism prevents renal vasoconstriction and hypoxia caused by hemorrhage. Read More

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Treating ARDS-associated air embolism: a question of priorities.

Undersea Hyperb Med 2021 Second Quarter;48(2):169-172

Intensive Care Unit and Hyperbaric Center, Lille University Hospital, Lille, France.

Gas embolism is a potential and often life-threatening complication of central venous catheters. We report a case of air embolism after tearing of the central catheter associated with severe acute respiratory distress syndrome. The severity of the clinical situation meant choices had to be made regarding the order of treatments. Read More

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Association of Adherence to Surfactant Best Practice Uses With Clinical Outcomes Among Neonates in Sweden.

JAMA Netw Open 2021 May 3;4(5):e217269. Epub 2021 May 3.

Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

Importance: While surfactant therapy for respiratory distress syndrome (RDS) in preterm infants has been evaluated in clinical trials, less is known about how surfactant is used outside such a framework.

Objective: To evaluate registered use, off-label use, and omissions of surfactant treatment by gestational age (GA) and associations with outcomes, mainly among very preterm infants (GA <32 weeks).

Design, Setting, And Participants: This population-based cohort study used registry data for 97 377 infants born in Sweden between 2009 and 2018. Read More

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Steroids for the Management of Neonates With Meconium Aspiration Syndrome: A Systematic Review and Meta-analysis.

Indian Pediatr 2021 Apr;58(4):370-376

Division of Neonatology, University of Toronto, and Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada.

Background: Steroids are a potential treatment for pulmonary inflammation in meconium aspiration syndrome (MAS).

Objective: To assess the efficacy and safety of steroids for the management of neonates with MAS.

Design: Systematic review and meta-analysis of randomized controlled trials (RCT). Read More

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A randomized single-center controlled trial of synchronized intermittent mandatory ventilation with heliox in newborn infants with meconium aspiration syndrome.

Pediatr Pulmonol 2021 Apr 8. Epub 2021 Apr 8.

Department of Neonatology, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, National Clinical Research Center for Child Health and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.

Objective: This study aimed to investigate the beneficial effects of synchronized intermittent mandatory ventilation (SIMV) with heliox in newborn infants with meconium aspiration syndrome (MAS).

Methods: Seventy-one newborn infants with MAS in the neonatal intensive care unit (NICU) of Daping Hospital of Army Medical University were enrolled in the trial. Infants treated with SIMV were randomized and divided into the heliox group (n = 35) and control group (n = 36). Read More

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Anesthesia for GI endoscopy in the era of COVID-19.

Saudi J Anaesth 2021 Jan-Mar;15(1):27-32. Epub 2021 Jan 5.

Department of Anesthesiology, Washington University in Saint Louis, Saint Louis, MO, USA.

As a result of COVID-19, the last few weeks have necessitated a reevaluation of the sedation paradigm for gastrointestinal (GI) endoscopic procedures. Routine screening and some surveillance procedures have taken a backseat and likely to remain so until a vaccine or effective treatment becomes available. Anesthesia providers and endoscopists are required to adapt to this new reality rapidly. Read More

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January 2021

Neonatal Respiratory Distress Secondary to Meconium Aspiration Syndrome.

Children (Basel) 2021 Mar 23;8(3). Epub 2021 Mar 23.

Department of Pediatrics, Case Western Reserve University, UH Rainbow Babies & Children's Hospital, 11100 Euclid Ave, Cleveland, OH 44106, USA.

Infants born through meconium-stained amniotic fluid (MSAF) are 100 times more likely than infants born through clear amniotic fluid to develop respiratory distress in the neonatal period. Meconium aspiration syndrome (MAS) is a common cause of respiratory distress in term and post-mature neonates. MAS is defined as respiratory distress accompanied by a supplemental oxygen requirement in an infant born with MSAF, in the absence of any other identified etiology to explain the symptoms. Read More

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Nutritional management in inpatients with aspiration pneumonia: a cohort medical claims database study.

Arch Gerontol Geriatr 2021 Jul-Aug;95:104398. Epub 2021 Mar 18.

Medical Affairs Department, Otsuka Pharmaceutical Factory, Inc., 2-9 Kanda-Tsukasamachi, Chiyoda-ku, Tokyo, Japan.

Background/objectives: This study aimed to describe real-world nutrition management patterns among inpatients hospitalized for aspiration pneumonia, using a medical claims database in Japan.

Methods: Patients aged ≥65 years hospitalized for aspiration pneumonia treatment were identified in a medical claims database between January 2013 and December 2018, to evaluate nutrition management initiation and adjustment timing, factors associated with >7-days nil per os (NPO) status, prescribed nutrition doses, and types of parenteral nutrition solutions. Patients who received oral intake or enteral nutrition on the day of admission (Day 1) were excluded. Read More

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Pneumothorax Induced by Computed Tomography Guided Transthoracic Needle Biopsy: A Review for the Clinician.

Int J Gen Med 2021 23;14:1013-1022. Epub 2021 Mar 23.

Department of Radiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.

Percutaneous computed tomography (CT)-guided transthoracic needle biopsy (TTNB) is a valuable procedure for obtaining tissue or cells for diagnosis, which is especially indispensable in thoracic oncology. Pneumothorax and hemoptysis are the most common complications of percutaneous needle biopsy of the lung. According to reports published over the past decades, pneumothorax incidence in patients who underwent TTNB greatly varies. Read More

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Open and Closed Endotracheal Suction Systems Divergently Affect Pulmonary Function in Mechanically Ventilated Subjects.

Respir Care 2021 May 9;66(5):785-792. Epub 2021 Mar 9.

Departamento de Educação Integrada em Saúde, Universidade Federal do Espírito Santo (UFES), Vitória, Espírito Santo, Brazil. Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts.

Background: In mechanically ventilated subjects, intra-tracheal secretions can be aspirated with either open suction systems (OSS) or closed suction systems (CSS). In contrast to CSS, conventional OSS require temporarily disconnecting the patient from the ventilator, which briefly diminishes PEEP and oxygen supply. On the other hand, CSS are more expensive and less effective at aspirating secretions. Read More

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A fully automated pipeline for the dynamic at-line morphology analysis of microscale Aspergillus cultivation.

Fungal Biol Biotechnol 2021 Mar 6;8(1). Epub 2021 Mar 6.

Institute of Bio- and Geosciences, Forschungszentrum Jülich GmbH, IBG-1: Biotechnology, Jülich, Germany.

Background: Morphology, being one of the key factors influencing productivity of filamentous fungi, is of great interest during bioprocess development. With increasing demand of high-throughput phenotyping technologies for fungi due to the emergence of novel time-efficient genetic engineering technologies, workflows for automated liquid handling combined with high-throughput morphology analysis have to be developed.

Results: In this study, a protocol allowing for 48 parallel microbioreactor cultivations of Aspergillus carbonarius with non-invasive online signals of backscatter and dissolved oxygen was established. Read More

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Nasal respiratory support and tachypnea and oral feeding in full-term newborn lambs.

J Appl Physiol (1985) 2021 May 4;130(5):1436-1447. Epub 2021 Mar 4.

Neonatal Respiratory Research Unit, Departments of Pediatrics and Pharmacology-Physiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

Newborn infants with respiratory difficulties frequently require nasal respiratory support such as nasal continuous positive airway pressure (nCPAP) or high-flow nasal cannulae (HFNC). Oral feeding of these infants under nasal respiratory support remains controversial out of fear of aspiration and cardiorespiratory events. The main objective of this study was to evaluate the safety of oral feeding under different types of nasal respiratory support in newborn lambs without or with tachypnea. Read More

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A comparison of gastric gas volumes measured by computed tomography after high-flow nasal oxygen therapy or conventional facemask ventilation.

Anaesthesia 2021 Mar 2. Epub 2021 Mar 2.

Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

High-flow nasal oxygen therapy is increasingly used to improve peri-intubation oxygenation. However, it is unknown whether it may cause or exacerbate insufflation of gas into the stomach. High-flow nasal oxygen therapy is now standard practice in our hospital for adult patients undergoing percutaneous thermal ablation of liver cancer under general anaesthesia with tracheal intubation. Read More

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Bronchoscopy for diagnosis of COVID-19 with respiratory failure: A case report.

World J Clin Cases 2021 Feb;9(5):1132-1138

Department of Respiratory and Critical Care Medicine, Hainan General Hospital, Haikou 570311, Hainan Province, China.

Background: Although the imaging features of coronavirus disease 2019 (COVID-19) are starting to be well determined, what actually occurs within the bronchi is poorly known. Here, we report the processes and findings of bronchoscopy in a patient with COVID-19 accompanied by respiratory failure.

Case Summary: A 65-year-old male patient was admitted to the Hainan General Hospital on February 3, 2020 for fever and shortness of breath for 13 d that worsened for the last 2 d. Read More

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February 2021

Tracheal stenosis due to cervicothoracic hyperlordosis in patients with cerebral palsy treated with posterior spinal fusion: a report of the first two cases.

BMC Musculoskelet Disord 2021 Feb 23;22(1):217. Epub 2021 Feb 23.

Department of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan.

Background: Spinal deformity is frequently identified in patients with cerebral palsy (CP). As it progresses, tracheal stenosis often develops due to compression between the innominate artery and anteriorly deviated vertebrae at the apex of the cervicothoracic hyperlordosis. However, the treatment strategy for tracheal stenosis complicated by spinal deformity in patients with CP remains unknown. Read More

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February 2021

Oral feeding for infants and children receiving nasal continuous positive airway pressure and high flow nasal cannula: a systematic review.

BMC Pediatr 2021 02 17;21(1):83. Epub 2021 Feb 17.

Allied Health Sciences & Menzies Health Institute Queensland Griffith University, Gold Coast, Australia.

Background: The aim of this systematic review was to determine whether introduction of oral feeding for infants and children receiving nasal continuous positive airway pressure (nCPAP) or high flow nasal cannula (HFNC) respiratory support facilitates achievement of full oral feeding without adverse effects, compared to no oral feeding (NPO; nil per oral) on CPAP or HFNC.

Methods: A protocol was lodged with the PROSPERO International Prospective Register of Systematic Reviews. We searched Medline, Embase, CINAHL, CENTRAL and AustHealth from database inception to 10th June 2020. Read More

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February 2021

The use of supplemental hydrocortisone in the management of persistent pulmonary hypertension of the newborn.

J Perinatol 2021 Apr 15;41(4):794-800. Epub 2021 Feb 15.

Department of Pediatrics, Duke University, Durham, NC, USA.

Objective: Characterize association between hydrocortisone receipt and hospital outcomes of infants with persistent pulmonary hypertension of the newborn (PPHN).

Study Design: Cohort study of infants ≥34 weeks with PPHN who received inhaled nitric oxide at <7 days of age (2010-2016). We generated propensity scores, and performed inverse probability-weighted regression to estimate hydrocortisone effect on outcomes: death, chronic lung disease (CLD), oxygen at discharge. Read More

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Overlooking the Obvious during the COVID-19 Pandemic: Dyspnoea with Asymmetric Breath Sounds in a Toddler.

Case Rep Pediatr 2021 2;2021:8855962. Epub 2021 Feb 2.

Department of Anaesthesia and Intensive Care, New Children's Hospital, University of Helsinki and Helsinki University Hospital, P.O. Box 347, Fi-00029 HUS, Finland.

Background: Paediatric healthcare specialists are concerned about the secondary effects of the COVID-19 pandemic on children. We report a case of acute respiratory distress in a healthy toddler whose healthcare providers were sidetracked from the correct diagnosis by suspicion of COVID-19. . Read More

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February 2021

Is the Use of Opioids Safe after Primary Cleft Palate Repair? A Systematic Review.

Plast Reconstr Surg Glob Open 2021 Jan 22;9(1):e3355. Epub 2021 Jan 22.

San Bartolome Mother and Children Hospital, Lima, Peru.

Pharmacologic treatment of postoperative pain after cleft palate repair includes opioids and nonopioid analgesics, nerve blocks, and local anesthetic infiltration. Use of opioids in infants has concerns regarding sedation, risk of aspiration, respiratory depression, and respiratory distress. The main objective of this review was to analyze information available on the safety of the use of opioids during perioperative management of pain related to primary cleft palate repair in published studies. Read More

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January 2021

Evaluation of Morbidities and Complications of Neonatal İntensive Care Unit Patients with Respiratory Disorders at Different Gestational Ages.

Am J Perinatol 2021 Jan 31. Epub 2021 Jan 31.

Division of Neonatology, Zekai Tahir Burak Women's Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey.

Objective:  Respiratory distress presented within the first few days of life is life-threatening and common problem in the neonatal period. The aim of this study is to estimate (1) the incidence of respiratory diseases in newborns and related mortality; (2) the relationship between acute neonatal respiratory disorders rates and gestational age, birth weight, and gender; and (3) the incidence of complications associated with respiratory disturbances.

Study Design:  Only inborn patients with gestational age between 23 and 41 weeks having respiratory distress were included in the study. Read More

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January 2021

The effect of Oxygen application with nCPAP for the prevention of desaturation during EBUS-TBNA.

Int J Clin Pract 2021 May 11;75(5):e14045. Epub 2021 Feb 11.

Department of Anesthesiology, Dokuz Eylul University, Izmir, Turkey.

Purpose: EBUS-TBNA is a frequently used diagnostic method for mediastinal/hilar lymphadenopathies and masses. This procedure is performed with intravenous sedation (IVS). During IVS, patients often develop hypoxemia and nasal oxygen delivery is insufficient in some patients. Read More

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Acute lung injury - from pathophysiology to treatment.

D Mokrá

Physiol Res 2020 12;69(Suppl 3):S353-S366

Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic.

Acute lung injury is characterized by acute respiratory insufficiency with tachypnea, cyanosis refractory to oxygen, decreased lung compliance, and diffuse alveolar infiltrates on chest X-ray. The 1994 American-European Consensus Conference defined "acute respiratory distress syndrome, ARDS" by acute onset after a known trigger, severe hypoxemia defined by PaO2/FiO2Read More

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December 2020

To Take One's Breath Away: Echocardiography-Guided Aspiration of an Air Embolism During a MitraClip Procedure.

CJC Open 2021 Jan 3;3(1):115-117. Epub 2020 Sep 3.

Quebec Heart & Lung Institute, Laval University, Québec City, Québec, Canada.

An air embolism (AE) is a rare but dreaded complication during endovascular procedures. Current guidance recommends hyperbaric oxygen therapy and aspiration for the management of a venous AE. However, the management of an arterial AE is much less described. Read More

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January 2021

Comparison of hypoxemia, intubation procedure, and complications for non-invasive ventilation against high-flow nasal cannula oxygen therapy for patients with acute hypoxemic respiratory failure: a non-randomized retrospective analysis for effectiveness and safety (NIVaHIC-aHRF).

Chao Zhang Min Ou

BMC Emerg Med 2021 01 14;21(1). Epub 2021 Jan 14.

The Sixth Department of Health Care, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100048, China.

Background: Optimization of preoxygenation procedure can help to secure the method of intubation by reducing the risks of severe hypoxemia and other problems. There is confusion for efficacy of non-invasive ventilation compared to high-flow oxygen therapy regarding occurrence of severe hypoxemia during the intubation procedure. The purpose of the study was to compare the difference between noninvasive ventilation and high flow oxygen therapy to prevent desaturation during laryngoscopy. Read More

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January 2021

Clinical and echocardiography predictors of response to inhaled nitric oxide in hypoxemic term and near-term neonates.

Pediatr Pulmonol 2021 May 12;56(5):982-991. Epub 2021 Jan 12.

Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.

Approximately 40% of hypoxemic term/near-term neonates are nonresponders to inhaled nitric oxide (iNO). Phenotypic characterization of patients less likely to respond may improve diagnostic precision and therapeutic decisions. We conducted a retrospective cohort study of neonates born ≥35 weeks gestation with hypoxemia who received iNO in the first 72 h of life and classified them into responders and nonresponders according to changes in the fraction of inspired oxygen, saturations and/or arterial partial pressure of oxygen after 1 h of administration. Read More

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