35,299 results match your criteria aspiration cytology

A Difficult Case of Pyrexia of Unknown Origin.

Indian J Pediatr 2021 Sep 25. Epub 2021 Sep 25.

Department of Microbiology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, Maharashtra, India.

This is the case of a 15-y-old boy who presented with fever and back pain with MRI features of spondylitis. A CT-guided vertebral biopsy showed acute and chronic inflammatory cells and grew Pseudomonas aeruginosa on aerobic culture. The child was treated for 2 wk with antibiotics with no response. Read More

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September 2021

Hepatic hemangioendothelioma - A rare case report.

Int J Surg Case Rep 2021 Sep 20;87:106424. Epub 2021 Sep 20.

Pir Abdul Qadir shah Jeelani Institute of Medical Sciences, Gambat, Sindh, Pakistan.

Introduction And Importance: Hepatic hemangioendothelioma (HHE) is a very rare mild-moderate malignant tumor of the hepatic vascular endothelium. The etiology is yet not fully understood. Patients can be asymptomatic or may present with non-specific symptoms or hepatic insufficiency. Read More

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September 2021

Granulomatous Mastitis: A Clinical and Diagnostic Dilemma.

Turk Patoloji Derg 2021 Sep 24. Epub 2021 Sep 24.

Department of Pathology, Tepecik Education and Research Hospital, University of Health Sciences, IZMIR, TURKEY.

Objective: Granulomatous mastitis (GM) is a challenging inflammatory disorder of the breast. In this study we aimed to present the detailed clinical and morphological features of GM cases, diagnostic clues for specific and idiopathic etiologies, the difficulties in evaluating trucut biopsies, and the results of different therapeutic approaches.

Material And Method: We retrospectively analysed the clinical, radiological and morphological features of 114 GM cases diagnosed with fine needle aspiration, and trucut, incisional, and excisional biopsy. Read More

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September 2021

Soft tissue recurrence of giant cell tumor of metacarpal bone: Report of an unusual case diagnosed by fine needle aspiration cytology.

Diagn Cytopathol 2021 Sep 23. Epub 2021 Sep 23.

Department of Pathology, Seth G.S. Medical College and King Edward Memorial Hospital, Mumbai, India.

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September 2021

Inferring gene regulatory networks from single-cell RNA-seq temporal snapshot data requires higher-order moments.

Patterns (N Y) 2021 Sep 18;2(9):100332. Epub 2021 Aug 18.

Mathematics of Complex Systems, Zuse Institute Berlin, 14195 Berlin, Germany.

Single-cell RNA sequencing (scRNA-seq) has become ubiquitous in biology. Recently, there has been a push for using scRNA-seq snapshot data to infer the underlying gene regulatory networks (GRNs) steering cellular function. To date, this aspiration remains unrealized due to technical and computational challenges. Read More

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September 2021

Cytopathologic Characteristics of Solitary Fibrous Tumor Involving the Pancreas by Fine-needle Aspiration: Making an Accurate Preoperative Diagnosis in an Uncommon Location.

Cytopathology 2021 Sep 22. Epub 2021 Sep 22.

Department of Pathology & Laboratory Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA.

Background: Solitary fibrous tumor (SFT) is a unique mesenchymal neoplasm with classic features on histology and is characterized by the NAB2-STAT6 gene fusion. There are rare reports of SFTs with pancreatic involvement and only two cases in the literature reporting its features by preoperative fine-needle aspiration (FNA). Herein, we characterize the cytomorphologic features of four SFTs involving the pancreas by FNA to establish a preoperative diagnostic approach. Read More

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September 2021

Sometimes You Have to Judge a Book by Its Cover: The Case of a Masquerading Pancreatic Mucinous Cyst.

ACG Case Rep J 2021 Apr 27;8(4):e00554. Epub 2021 Apr 27.

Division of Gastroenterology and Hepatology, Department of Medicine, Strong Memorial Hospital, University of Rochester Medical Center, Rochester, NY.

Pancreatic cystic lesions are difficult to evaluate amid acute pancreatitis. Without previous pancreatic imaging, it is challenging to discern between pancreatic acute fluid collections and cystic neoplasms. We present a 29-year-old woman with acute pancreatitis and initial cross-sectional imaging suggesting a 2. Read More

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Ultrasound-Based Indications for Thyroid Fine-Needle Aspiration: Outcome of a TIRADS-Based Approach versus Operators' Expertise.

Eur Thyroid J 2021 Jul 25;10(5):416-424. Epub 2020 Nov 25.

Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Background: Thyroid nodule image reporting and data systems (TIRADS) provide the indications for fine-needle aspiration (FNA) based on a combination of nodule sonographic features and size. We compared the TIRADS-based recommendations for FNA with those based on the personal expertise of qualified US investigators in the diagnosis of thyroid malignancy.

Methods: Seven highly experienced ultrasound (US) investigators from 4 countries evaluated, online, the US video recordings of 123 histologically verified thyroid nodules. Read More

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Malignancy Rates of Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance (AUS/FLUS) Cases: A Tertiary Center Study.

Acta Endocrinol (Buchar) 2021 Apr-Jun;17(1):77-82

Erzurum Training and Research Hospital - Pathology, Erzurum, Turkey.

Aim: To evaluate the malignancy rates of Atypia of undetermined significance /follicular lesion of undetermined significance (AUS/FLUS) cases in the light of clinical and sonographic features.

Material And Methods: The percentage of AUS/FLUS cases, second fine needle aspiration cytology (FNAC) results, cyto-histopathological correlations and risk of malignancy were analyzed.

Results: 113 out of 1461 thyroid FNAC samples (7. Read More

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October 2021

Risk Stratification of Breast Fine-Needle Aspiration Biopsy Specimens Performed without Radiologic Guidance by Application of the International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Cytopathology.

Acta Cytol 2021 Sep 14:1-11. Epub 2021 Sep 14.

Department of Radiation Oncology, All India Institute of Medical Sciences (AIIMS), Jodhpur, India.

Background And Objective: The International Academy of Cytology (IAC) Yokohama system for reporting breast fine-needle aspiration biopsy (FNAB) cytopathology has been proposed to standardize breast FNAB reporting. The aim of this study was to categorize breast FNAB cases performed by palpation without radiological guidance according to the IAC system, establish the risk of malignancy (ROM) for the categories and assess the system's utility, pitfalls, and implications in low-resource/financial constraint settings.

Methods: A retrospective analysis of palpation-guided FNAB of breast lesions performed without radiological guidance between January 2016 and December 2019 was carried out and was correlated with follow-up biopsies wherever available. Read More

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September 2021

Endoscopic tissue sampling - Part 1: Upper gastrointestinal and hepatopancreatobiliary tracts. European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Endoscopy 2021 Sep 17. Epub 2021 Sep 17.

Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.

1: ESGE recommends that, where there is a suspicion of eosinophilic esophagitis, at least six biopsies should be taken, two to four biopsies from the distal esophagus and two to four biopsies from the proximal esophagus, targeting areas with endoscopic mucosal abnormalities. Distal and proximal biopsies should be placed in separate containers.Strong recommendation, low quality of evidence. Read More

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September 2021

Hyaline Vascular Type of Castleman Disease: Diagnostic Pitfalls on Cytology and Its Clinical Relevance.

Cureus 2021 Aug 14;13(8):e17174. Epub 2021 Aug 14.

Pathology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Castleman disease (CD) is an uncommon cause of lymphadenopathy. The role of fine-needle aspiration cytology (FNAC) as a diagnostic modality in this disease is not well established. Cytological features of CD have a considerable overlap with many reactive conditions. Read More

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Thyroid diagnostic modalities (fine needle aspiration and core needle biopsy) with histology correlation: a tertiary centre experience.

J Clin Pathol 2021 Sep 16. Epub 2021 Sep 16.

Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Aims: To determine the proportion of thyroid fine needle aspiration (FNA) and core needle biopsy (CNB) cases reported at a single institute into each UK Royal College of Pathologists (RCPath) Thy1-5 and local T category, respectively. Where subsequent histology was available, malignancy rates, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy were compared for both procedures.

Methods: 1591 FNAs (2010-2018) and 514 CNBs (2013-2018) cases were identified, together with paired histology excision specimens. Read More

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September 2021

Clinical and cytopathological features of suspected thyroglossal duct cysts and neoplasms arising from them: A large series from a referral cancer center.

Cancer Cytopathol 2021 Sep 16. Epub 2021 Sep 16.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Thyroglossal duct cysts (TGDCs) are the most common congenital midline cystic lesions in the neck, and they are often evaluated by fine-needle aspiration. Recognizing the cytomorphologic features of TGDCs and their mimics is important for clinical management.

Methods: This study examined the clinical, radiological, and cytopathological features of 86 ultrasonography-guided fine-needle aspiration (US-FNA) specimens from clinically suspected TGDCs or malignancies arising from TGDCs and correlated the findings with surgical follow-up and/or imaging studies. Read More

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September 2021

Pleomorphic liposarcoma with liver metastasis diagnosed by combined fine-needle aspiration cytology and core-needle biopsy.

Diagn Cytopathol 2021 Sep 15. Epub 2021 Sep 15.

Department of Medicine and Surgery, University of Salerno, Salerno, Italy.

Pleomorphic liposarcoma (PLPS) is the rarest liposarcoma subtype, with high-local recurrence and metastasis rates. Fine-needle aspiration cytology (FNAC) is successfully used in the diagnosis of primary or metastatic soft tissue tumors, but liver metastases of PLPS diagnosed by FNAC have never been reported. The cytological diagnosis depends on the identification of lipoblasts with sharply defined cytoplasmic vacuoles indenting and distorting the nucleus in the context of a pleomorphic tumor and in a proper clinical and imaging context. Read More

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September 2021

Accuracy of fine-needle aspiration of lymph nodes: A Cancer Center experience.

Cytopathology 2021 Sep 16. Epub 2021 Sep 16.

Department of Pathology, AC Camargo Cancer Center.

Introduction: Lymph node fine needle aspiration (LN-FNA) is a minimally invasive method to evaluate lymphadenopathy. Nonetheless, its use is not widely accepted due to the lack of guidelines and a cytopathological categorization that directly relates to management. We report our experience with LN FNA at a large Cancer Center in Latin America. Read More

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September 2021

Solitary Intrathyroid Metastasis Occurring 23 Years after Resection of Renal Cell Carcinoma.

X Vandemergel

Case Rep Endocrinol 2021 4;2021:2735256. Epub 2021 Sep 4.

Department of Endocrinology, EpiCURA, Boussu, Belgium.

A case of solitary intrathyroid metastasis is described in a 60-year-old male patient. He had a history of renal cell carcinoma classified as T1b resected 23 years earlier. A mass was palpable in the right thyroid lobe. Read More

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September 2021

Utility of ultrasound guided versus conventional fine needle aspiration cytology in diagnosing breast malignancies among patients with palpable breast lumps at Bugando Medical Centre, Mwanza Tanzania.

Pan Afr Med J 2021 16;39:133. Epub 2021 Jun 16.

Department of Pathology, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.

Introduction: breast lump is the commonest presentation for both benign and maligant breast conditions. Both ultrasound guided and conventional fine needle aspiration cytology (FNAC) have been used for diagnosing of breast malignancy among patients with palpable breast lumps. This study compared diagnostic utility of ultrasound guided versus conventional FNAC in diagnosing breast malignancies among patients with palpable breast lumps at Bugando Medical Centre. Read More

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Cytomorphological and immunocytochemical diagnosis of an oesophageal mass in a 62-year-old female with dysphagia.

Cytopathology 2021 Sep 15. Epub 2021 Sep 15.

Department of Cytology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Oesophageal schwannoma is an extremely rare benign neoplasm. Cytological diagnosis of oesophageal schwannoma has been sporadically reported in the literature. Herein, we present a case of oesophageal schwannoma in an older woman that could be accurately diagnosed based on endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology accompanied by cell block immunocytochemistry. Read More

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September 2021

Giant Multilobular Lipoma of Neck - A Case Report.

Ann Maxillofac Surg 2021 Jan-Jun;11(1):160-163. Epub 2021 Jul 24.

Department of Oral and Maxillofacial Pathology, Nair Hospital Dental College, Mumbai, Maharashtra, India.

Rationale: Presenting a rare case report of a giant multilobular lipoma in submandibular and submental spaces of anterior and lateral aspect of neck.

Patient's Concerns: The patient's main concern was persistent diffuse swelling in right lower face and neck region for 5-6 years.

Diagnosis: The lesion was diagnosed as multiple septate lipoma measuring 11. Read More

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The Pattern of Superficial Lymphadenopathy on Fine Needle Aspiration Cytology in Clinical Practice in Islamabad.

Cureus 2021 Aug 10;13(8):e17075. Epub 2021 Aug 10.

Medical Affairs and Clinical Research, Hilton Pharma Pvt. Ltd., Karachi, PAK.

Background:  In adults, lymph nodes are not normally palpable. A number of patients with asymptomatic lymphadenopathy never visit physicians for the condition, and thus, this important sign is often missed by the medical practitioner if it is not the presenting complaint. The incidence of lymphadenopathy is suggested to be increasing. Read More

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High diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of adolescent pulmonary tuberculosis.

BMC Infect Dis 2021 Sep 14;21(1):946. Epub 2021 Sep 14.

Department of Pediatrics and Adolescent Medicine, University Medical Center, Medical Faculty, University of Freiburg, Freiburg, Germany.

Background: The microbiological diagnosis of pulmonary tuberculosis (Tb) in a pediatric population is hampered by both low pathogen burden and noncompliance with sputum sampling. Although endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been found useful for the evaluation of mediastinal pathologies in adults, for children, sparse data are available. Here, we have evaluated EBUS-TBNA as a diagnostic procedure in children and adolescents with suspected pulmonary Tb. Read More

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September 2021

Calcitonin levels in washout samples vs. cytology in detection of malignant lymph node metastasis in recurrent medullary thyroid cancer.

Turk J Med Sci 2021 Sep 14. Epub 2021 Sep 14.

Background: Calcitonin level in fine-needle aspirate washout fluid (Ct-FNA) was extensively studied for thyroid nodules and lymph nodes (LN). However, the data was scarce for neck recurrences/metastases of medullary thyroid cancer (MTC). Thus, the diagnostic accuracy of Ct-FNA and cytology in detection of neck LN metastases of recurrent MTC cases were assessed. Read More

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September 2021

Thyroid sarcoidosis: a rare entity in the differential diagnosis of thyroid cancer.

Endocrinol Diabetes Metab Case Rep 2021 Sep 1;2021. Epub 2021 Sep 1.

Endocrinology Department, Thessaloniki, Greece.

Summary: We present two cases of thyroid sarcoidosis that were misdiagnosed as thyroid cancer. In the first patient, fine needle aspiration cytology (FNAc) of a suspicious thyroid nodule indicated the presence of papillary thyroid cancer, and the patient underwent thyroid surgery. However, histopathology identified a sarcoid granuloma, without any sign of malignancy. Read More

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September 2021

Microcalcifications without a thyroid nodule as the sole sign of papillary thyroid carcinoma.

Endocrinol Diabetes Metab Case Rep 2021 Sep 1;2021. Epub 2021 Sep 1.

CEDM, Centre of Endocrinology, Diabetes and Metabolism, Limassol, Cyprus.

Summary: Our objective is to demonstrate the importance of considering microcalcifications even without evidence of nodules as a potential sign of malignancy. Current guidelines, such as those of the British Thyroid Association, acknowledge the clinical significance of microcalcifications only when found within nodules. In this case, they are considered a suspicious feature, classifying the nodules as U5 (i. Read More

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September 2021

Fine-Needle Aspiration Cytology in the Diagnosis of Breast Paraffinoma.

Acta Cytol 2021 Aug 31:1-5. Epub 2021 Aug 31.

Department of Surgery, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan, Brunei Darussalam.

Introduction: Paraffin injections for breast augmentation once a popular form of mammoplasty are now considered obsolete. It had been abandoned by clinicians because of its associated serious complications. The practice is however still available and is being practiced by nonmedically qualified people. Read More

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Fine-Needle Aspiration Biopsy Cytopathology of Breast Lesions Using the International Academy of Cytology Yokohama System and Rapid On-Site Evaluation: A Single-Institute Experience.

Acta Cytol 2021 Aug 27:1-15. Epub 2021 Aug 27.

Sir HN Reliance Foundation Hospital, Mumbai, India.

Introduction: Breast cancer is rapidly emerging as the leading cause of cancer in Indian women. Robust cytopathology and histopathology services are required to tackle this growing burden. The use of rapid on-site evaluation (ROSE) and the International Academy of Cytology (IAC) Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy (FNAB) Cytopathology, which offers structured protocols, are expected to improve breast cytopathology reporting. Read More

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Peripheral Lymphadenopathy in Children: Cytomorphological Spectrum and Interesting Diagnoses.

Turk Patoloji Derg 2021 ;37(3):219-225

Department of Pathology, Chacha Nehru Bal Chikitsalaya, DELHI, INDIA.

Objective: Peripheral lymphadenopathy is a common complaint in the pediatric outpatient department. Fine needle aspiration cytology is the first investigation of choice with a high sensitivity for diagnosis but cytology may be challenging in some cases. The study was planned to study the cytomorphological spectrum and discuss a few interesting cases. Read More

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January 2021

The Role of Immunocytochemical Markers to Differentiate Primary from Secondary Neoplastic Hepatic Masses: A Diagnostic Challenge on Cytology.

Turk Patoloji Derg 2021 ;37(3):196-202

Department of Pathology, Lady Hardinge Medical College, NEW DELHI, INDIA.

Objective: It is challenging and difficult to differentiate primary from metastatic hepatic masses solely on cytology. The present study aimed to correlate cytomorphological spectrum of hepatic masses with immunocytochemical markers to differentiate primary from metastases in liver.

Material And Method: The present study comprised of 30 clinico-radiologically suspicious cases of neoplastic hepatic masses. Read More

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January 2021

Risk stratification by application of Milan system for reporting salivary gland cytopathology: A tertiary care experience.

Cytojournal 2021 2;18:19. Epub 2021 Aug 2.

Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Objectives: The Milan system for reporting salivary gland cytopathology (MSRSGC) classification has been proposed to improve reproducibility in the management of salivary gland lesions. Fine-needle aspiration cytology (FNAC) is a widely accepted, well-tolerated, cost-effective, minimally invasive diagnostic method for pre-operative evaluation of salivary gland lesion that aids management decisions. The present study aims to reclassify the salivary gland FNAC aspirates by applying MSRSGC and calculating the risk of neoplasm and malignancy for each diagnostic category. Read More

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