Bioorg Med Chem Lett 2021 Mar 31:128004. Epub 2021 Mar 31.
Department of Chemistry, Nizam College, Osmania University, Hyderabad, Telangana, 500001, India. Electronic address:
A new series of bis-1,2,3- and 1,2,4-triazoles (10a-m) were designed and efficiently synthesized using methyl salicylate as a starting material as potential antimicrobial agents. All compounds were characterized by their proton &C NMR, IR, Mass spectral data, and elemental analysis. The final compounds 10a-m were in vitro screened for antimicrobial and antifungal activity against gram negative Pseudomonas aeruginosa, Escherichia coli, gram positive Bacillus subtilis, Staphylococcus aureus strains and Aspergillus niger &Saccharomyces cerevisiae. Read More