Magn Reson Imaging 2021 Mar 6;79:20-27. Epub 2021 Mar 6.
Vascular Imaging Lab, Department of Radiology, University of Washington, Seattle, WA, United States; BioMolecular Imaging Center, Department of Radiology, University of Washington, Seattle, WA, United States.
Purpose: To explore feasibility of using the vessel length on time-of-flight (TOF) or simultaneous non-contrast angiography and intraplaque hemorrhage (SNAP) MRA as an imaging biomarker for brain blood flow, by using arterial spin labeling (ASL) perfusion imaging and 3D phase contrast (PC) quantitative flow imaging as references.
Methods: In a population of thirty subjects with carotid atherosclerotic disease, the visible intracranial arteries on TOF and SNAP were semi-automatically traced and the total length of the distal segments was calculated with a dedicated software named iCafe. ASL blood flow was calculated automatically using the recommended hemodynamic model. Read More