Eur J Anaesthesiol 2021 01;38(1):4-12
From the Division of Anaesthesia and Intensive Care, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet (JJ, CN, SK, EB), Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital Huddinge, Stockholm (JJ, SK, EB), Department of Anaesthesia and Intensive Care, Nyköping County Hospital, Nyköping (CN) and Medical Statistics Unit, Department of Learning, Information, Management and Ethics (LIME), Karolinska Institutet, Stockholm, Sweden (EH).
Background: Monitoring oxygen consumption (VO2) is neither recommended nor included in peri-operative haemodynamic algorithms aiming at optimising oxygen delivery (DO2) in major abdominal surgery. Estimates of peri-operative VO2 changes are uncertain in earlier publications and have limited generalisability in the current high-risk surgical population. In a prospective non-interventional observational study in elderly patients undergoing major abdominal procedures, we investigated the change of VO2 after induction of anaesthesia and secondarily, the further changes during and after surgery in relation to DO2 and estimated oxygen extraction ratio (O2ER) by routine monitoring. Read More