17,694 results match your criteria arterial stiffness


[Quo vadimus? Fundamental problems of developing hybrid prostheses of thoracic aorta].

Angiol Sosud Khir 2021 ;27(4):103-112

Department of Aorta and Coronary Arteries Surgery, Laboratory of Bioprosthetics, National Medical Research Centre named after Academician E.N. Meshalkin, RF Ministry of Public Health, Novosibirsk, Russia.

This article is a review briefly characterizing the state of the art of hybrid surgery of the thoracic aorta using the frozen elephant trunk technique worldwide and in Russia, also discussing unsolved problems of fundamental science, being key issues in creation of new models of hybrid prostheses of the thoracic aorta. The main attention is paid to the problem of radial stiffness of the stent-graft portion of the prosthesis. Performed is a detailed analysis of the factors influencing this characteristic of the sent graft: shape, size and number of cells of the stent element, thickness of the nitinol wire it is made of, method of edge connection, nitinol properties depending on the alloy grade and methods of thermoforming. Read More

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January 2022

CD147 Levels in Blood and Adipose Tissues Correlate with Vascular Dysfunction in Obese Diabetic Adults.

J Cardiovasc Dev Dis 2021 Dec 28;9(1). Epub 2021 Dec 28.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

CD147 is a glycoprotein that stimulates the production of matrix metalloproteinases (MMPs), known contributors to cardiovascular risk. The activity of CD147 protein depends on its glycosylation. However, it is unclear whether CD147 protein expression or glycosylation are influenced by the diabetic milieu characterized by hyperglycemia and abundant glycation-end-products (AGEs). Read More

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December 2021

The Relationship Between Cardio-Ankle Vascular Index and Left Atrial Phasic Function in Hypertensive Patients With Preserved Ejection Fraction.

Front Med Technol 2021 31;3:724089. Epub 2021 Aug 31.

Department of Clinical Functional Physiology, Toho University Sakura Medical Center, Chiba, Japan.

To investigate the relationship between arterial stiffness, reflected by cardio-ankle vascular index (CAVI) value, and left atrial (LA) phasic function in hypertensive patients with preserved left ventricular ejection fraction (LVEF). We retrospectively studied 165 consecutive patients (mean age, 66.5 ± 11. Read More

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The Functional Polymorphism of rs9267551 Is an Independent Determinant of Arterial Stiffness.

Front Cardiovasc Med 2021 3;8:811431. Epub 2022 Jan 3.

Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.

The association of circulating asymmetric dimethylarginine (ADMA) levels with cardiovascular risk and arterial stiffness has been reportedly demonstrated, although the causal involvement of ADMA in the pathogenesis of these conditions is still debated. Dimethylaminohydrolase 2 (DDAH2) is the enzyme responsible for ADMA hydrolysis in the vasculature, and carriers of the polymorphism rs9267551 C in the 5'-UTR of have been reported to have higher expression and reduced levels of serum ADMA. We genotyped rs9267551 in 633 adults of European ancestry and measured their carotid-femoral pulse wave velocity (cfPWV), the gold-standard method to estimate arterial stiffness. Read More

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January 2022

Carotid Atherosclerosis Predicts Blood Pressure Control in Patients With Hypertension: The Campania Salute Network Registry.

J Am Heart Assoc 2022 Jan 19:e022345. Epub 2022 Jan 19.

Department of Advanced Biomedical Sciences Federico II University Naples Italy.

Background The 2018 European Society of Cardiology/European Society of Hypertension arterial hypertension guidelines do not recommend routine carotid ultrasound as a tool to identify hypertension-mediated organ damage, unless clinically indicated. However, carotid plaque (CP) is a strong correlate of increased arterial stiffness, which influences blood pressure (BP) control over time. Thus, we assessed whether evidence of CP at first visit could predict BP control during follow-up. Read More

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January 2022

Blood Pressure Complexity Discriminates Pathological Beat-to-Beat Variability as a Marker of Vascular Aging.

J Am Heart Assoc 2022 Jan 19:e022865. Epub 2022 Jan 19.

Wolfson Centre for Prevention of Stroke and DementiaNuffield Department of Clinical NeurosciencesJohn Radcliffe HospitalUniversity of Oxford UK.

Background Beat-to-beat blood pressure variability (BPV) is associated with an increased risk of stroke but can be driven by both healthy physiological processes and failure of compensatory mechanisms. Blood pressure (BP) complexity measures structured, organized variations in BP, as opposed to random fluctuations, and its reduction may therefore identify pathological beat-to-beat BPV. Methods and Results In the prospective, population-based OXVASC (Oxford Vascular Study) Phenotyped Cohort with transient ischemic attack or minor stroke, patients underwent at least 5 minutes of noninvasive beat-to-beat monitoring of BP (Finometer) and ECG to derive the following: BPV (coefficient of variation) and complexity (modified multiscale entropy) of systolic BP and diastolic BP, heart rate variability (SD of R-R intervals), and baroreflex sensitivity (BRS; Welch's method), in low- (0. Read More

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January 2022

[Masked arterial hypertension in patients with type2 diabetes mellitus: Prevalence, associated factors and cardiovascular impact].

Ann Cardiol Angeiol (Paris) 2022 Jan 14. Epub 2022 Jan 14.

Service d'endocrinologie, Hôpital Hédi Chaker Sfax Tunisie, Faculté de médecine de Sfax, Université de Sfax, Tunisie.

Problematic And Objective: Masked arterial hypertension (MHTN) is a recently described entity that is associated with the same cardiovascular risk as permanent hypertension. Its prevalence is more frequent in patients with diabetes. The objective of this study is to assess the value of systematic screening for MHTN by 24-hour blood pressure monitoring in a population of type 2 diabetic patients by estimating its prevalence and looking for predictive factors of MHTN in this population. Read More

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January 2022

Effect of Arterial Stiffness and Carotid Intima-Media Thickness Progression on the Risk of Dysglycemia, Insulin Resistance, and Dyslipidemia: a Temporal Causal Longitudinal Study.

Hypertension 2022 Jan 18:HYPERTENSIONAHA12118754. Epub 2022 Jan 18.

Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio (A.O.A., P.T.).

Background: We investigated the temporal causal longitudinal associations of carotid-femoral pulse wave velocity (cfPWV), a measure of arterial stiffness, and carotid intima-media thickness (cIMT) progression with the risk of dysglycemia, insulin resistance, and dyslipidemia.

Methods: We included 3862, 17.7-year-old, participants from the Avon Longitudinal Study of Parents and Children, followed up for 7 years. Read More

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January 2022

Biomechanical characterization and constitutive modeling of the layer-dissected residual strains and mechanical properties of abdominal porcine aorta.

J Biomech 2022 Jan 4;132:110909. Epub 2022 Jan 4.

Applied Mechanics and Bioengineering, Aragón Institute of Engineering Research (I3A), University of Zaragoza, Spain; Department of Mechanical Engineering, University of Zaragoza, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain. Electronic address:

We analyze the residual stresses and mechanical properties of layer-dissected infrarenal abdominal aorta (IAA). We measured the axial pre-stretch and opening angle and performed uniaxial tests to study and compare the mechanical behavior of both intact and layer-dissected porcine IAA samples under physiological loads. Finally, some of the most popular anisotropic hyperelastic constitutive models (GOH and microfiber models) were proposed to estimate the mechanical properties of the abdominal aorta by least-square fitting of the recorded in-vitro uniaxial test results. Read More

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January 2022

High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?

Int Urol Nephrol 2022 Jan 15. Epub 2022 Jan 15.

Department of Nephrology, Hypertension, Dialysis and Transplantation, School of Medicine, University Hospital Center Zagreb, 10000, Zagreb, Croatia.

Purpose: We have analyzed markers of accelerated atherosclerosis like large artery stiffness, ankle-brachial index, carotid and vertebral duplex ultrasonography and their possible associations with the incidence of intracranial calcifications, clinical course of hemodialyzed patients, and cardiovascular mortality.

Methods: A computed tomographic scan of the head was performed for any neurological indication on 100 hemodialyzed patients. Eleven intracranial arteries were analyzed for calcification score, while internal carotid arteries and vertebral arteries were excluded in cerebral artery calcification score. Read More

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January 2022

Arterial health during early childhood following abnormal fetal growth.

BMC Pediatr 2022 Jan 14;22(1):40. Epub 2022 Jan 14.

Children's Hospital, Pediatric Research Center, University of Helsinki, and Helsinki University Hospital, Stenbäckinkatu 9, POB 347, FIN-00029, Helsinki, Finland.

Background: Abnormal fetal growth is associated with increased cardiovascular risk in adulthood. We investigated the effect of fetal programming on arterial health and morphology during early childhood.

Methods: We examined 90 children (median age 5. Read More

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January 2022

The effects of exercise training on vascular function among overweight adults with obstructive sleep apnea.

Transl Sports Med 2021 Sep 28;4(5):606-616. Epub 2021 Apr 28.

Institut d'Investigacio Sanitaria Pere Virgili (IISPV), Reus, Spain.

Obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity due, in part, to impaired vascular function. Exercise confers cardioprotection by improving vascular health. Yet, whether OSA severity affects the vascular improvements conferred with exercise training is not known. Read More

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September 2021

Association of inter-arm systolic blood pressure differences with arteriosclerosis and atherosclerosis: A cohort study of 117,407 people.

Atherosclerosis 2021 Dec 31;342:19-24. Epub 2021 Dec 31.

Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Background And Aims: Inter-arm blood pressure differences (IADs) are known to be associated with adverse cardiovascular outcomes. We evaluated the distribution of IADs in a large cohort of apparently healthy people and the association of IADs with brachial-ankle pulse wave velocity (baPWV) and coronary artery calcium (CAC).

Methods: Blood pressure was measured in both arms of 117,407 people who participated in the Kangbuk Samsung Health Study. Read More

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December 2021

Diastolic Dysfunction With Preserved Ejection Fraction After the Fontan Procedure.

J Am Heart Assoc 2022 Jan 13;11(2):e024095. Epub 2022 Jan 13.

Division of Cardiology Department of Pediatrics Medical University of South Carolina Charleston SC.

Background Heart failure phenotyping in single-ventricle Fontan patients is challenging, particularly in patients with normal ejection fraction (EF). The objective of this study was to identify Fontan patients with abnormal diastolic function, who are high risk for heart failure with preserved ejection fraction (HFpEF), and characterize their cardiac mechanics, exercise function, and functional health status. Methods and Results Data were obtained from the Pediatric Heart Network Fontan Cross-sectional Study database. Read More

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January 2022

Carotid Artery Stiffness Mechanisms Associated With Cardiovascular Disease Events and Incident Hypertension: the MESA.

Hypertension 2022 Jan 13:HYPERTENSIONAHA12118772. Epub 2022 Jan 13.

University of Wisconsin School of Medicine and Public Health, Madison (R.J.P., C.K., A.D.G.).

Background: Elastic arteries stiffen via 2 main mechanisms: (1) load-dependent stiffening from higher blood pressure and (2) structural stiffening due to changes in the vessel wall. It is unknown how these different mechanisms contribute to incident cardiovascular disease (CVD) events.

Methods: The MESA (Multi-Ethnic Study of Atherosclerosis) is a longitudinal study of 6814 men and women without CVD at enrollment, from 6 communities in the United States. Read More

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January 2022

Smooth muscle mineralocorticoid receptor as an epigenetic regulator of vascular aging.

Cardiovasc Res 2022 Jan 10. Epub 2022 Jan 10.

Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA.

Aims: Vascular stiffness increases with age and independently predicts cardiovascular disease risk. Epigenetic changes, including histone modifications, accumulate with age but the global pattern has not been elucidated nor are the regulators known. Smooth muscle cell-mineralocorticoid receptor (SMC-MR) contributes to vascular stiffness in aging mice. Read More

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January 2022

Vascular Responses to Simulated Breath-Hold Diving Involving Multiple Reflexes.

Am J Physiol Regul Integr Comp Physiol 2022 Jan 12. Epub 2022 Jan 12.

Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX, United States.

Breath-hold diving evokes a complex cardiovascular response. The degrees of hypertension induced by the diving reflex are substantial and accentuated by the underwater swimming. This condition provides a circulatory challenge to properly buffer and cushion cardiac pulsations. Read More

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January 2022

Serum Level of Lactate Dehydrogenase is Associated with Cardiovascular Disease Risk as Determined by the Framingham Risk Score and Arterial Stiffness in a Health-Examined Population in China.

Int J Gen Med 2022 4;15:11-17. Epub 2022 Jan 4.

Department of Health Management Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China.

Introduction: Lactate dehydrogenase (LDH) is an important oxidoreductase in the anaerobic metabolic pathway. The role of LDH in arterial stiffness (AS) and 10-year cardiovascular disease (CVD10) risk has not been established.

Methods: This retrospective, cross-sectional, and observational study evaluated the relationships between the LDH level and AS and CVD10 risk in 12,597 health-examined people (6988 men and 5609 women; mean age, 49. Read More

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January 2022

Prevalence and predicting factors of increased arterial stiffness in autosomal dominant polycystic kidney disease.

Saudi J Kidney Dis Transpl 2021 Mar-Apr;32(2):481-487

Department of Nephrology, Rabta Hospital, Tunis, Tunisia.

Carotid-femoral pulse wave velocity (cf-PWV) is the noninvasive gold standard technique for measuring aortic stiffness. Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal disease in adults. It is associated with a high risk of cardiovascular complications. Read More

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January 2022

Cardiovascular function in 8- to 9-year-old singletons born after ART with frozen and fresh embryo transfer.

Hum Reprod 2022 Jan 7. Epub 2022 Jan 7.

Fertility Department, Copenhagen University Hospital, Rigshospitalet, Denmark, Copenhagen.

Study Question: Do 8- to 9-year-old singletons conceived after frozen embryo transfer (FET) or fresh embryo transfer (Fresh-ET) have increased arterial stiffness compared to naturally conceived (NC) children?

Summary Answer: The process of FET or Fresh-ET is not associated with altered cardiovascular function in 8- to 9-year-old singletons, including arterial stiffness, as compared to NC children.

What Is Known Already: ART has been suggested to influence cardiovascular risk factors (i.e. Read More

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January 2022

Endothelial-derived extracellular microRNA-92a promotes arterial stiffness by regulating phenotype changes of vascular smooth muscle cells.

Sci Rep 2022 Jan 10;12(1):344. Epub 2022 Jan 10.

Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Endothelial dysfunction and vascular smooth muscle cell (VSMC) plasticity are critically involved in the pathogenesis of hypertension and arterial stiffness. MicroRNAs can mediate the cellular communication between vascular endothelial cells (ECs) and neighboring cells. Here, we investigated the role of endothelial-derived extracellular microRNA-92a (miR-92a) in promoting arterial stiffness by regulating EC-VSMC communication. Read More

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January 2022

A Retrospective Cohort Study of the Association between Serum Osteopontin Levels and Aortic Stiffness in Hypertensive Patients.

Int J Environ Res Public Health 2022 01 2;19(1). Epub 2022 Jan 2.

Department of Internal Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.

By suppressing mineralization and preventing ectopic calcium deposits, osteopontin (OPN) has an inhibitory effect on vascular calcification. Also, there is an association between OPN and aortic stiffness (AS). We aimed to investigate the association between serum OPN levels and AS measured by carotid-femoral pulse wave velocity (cfPWV) in hypertensive patients. Read More

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January 2022

Multi-Channel Bioimpedance System for Detecting Vascular Tone in Human Limbs: An Approach.

Sensors (Basel) 2021 Dec 26;22(1). Epub 2021 Dec 26.

Department of Medical and Technical Information Technology, Bauman Moscow State Technical University, 105005 Moscow, Russia.

Vascular tone plays a vital role in regulating blood pressure and coronary circulation, and it determines the peripheral vascular resistance. Vascular tone is dually regulated by the perivascular nerves and the cells in the inside lining of blood vessels (endothelial cells). Only a few methods for measuring vascular tone are available. Read More

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December 2021

Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiovascular Remodelling in a Mouse Model of Advanced Atherosclerosis.

Int J Mol Sci 2021 Dec 30;23(1). Epub 2021 Dec 30.

Laboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.

Acetylsalicylic acid (ASA) is widely used in secondary prevention of cardiovascular (CV) disease, mainly because of its antithrombotic effects. Here, we investigated whether ASA can prevent the progression of vessel wall remodelling, atherosclerosis, and CV complications in apolipoprotein E deficient () mice, a model of stable atherosclerosis, and in mice with a mutation in the fibrillin-1 gene (), which is a model of elastic fibre fragmentation, accompanied by exacerbated unstable atherosclerosis. Female and mice were fed a Western diet (WD). Read More

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December 2021

Issue of Waist Circumference for the Diagnosis of Metabolic Syndrome Regarding Arterial Stiffness: Possible Utility of a Body Shape Index in Middle-Aged Nonobese Japanese Urban Residents Receiving Health Screening.

Obes Facts 2022 Jan 10:1-10. Epub 2022 Jan 10.

Department of Internal Medicine, Mihama Hospital, Chiba, Japan.

Introduction: Abdominal obesity as a risk factor for diagnosing metabolic syndrome (MetS) is evaluated using waist circumference (WC), although WC does not necessarily reflect visceral adiposity. This cross-sectional study aimed to clarify whether replacing WC with "A Body Shape Index (ABSI)," an abdominal obesity index, in MetS diagnosis detects individuals with arterial stiffening assessed by cardio-ankle vascular index (CAVI).

Methods: A retrospective cross-sectional study was conducted in 46,872 Japanese urban residents (median age 40 years) who underwent health screening. Read More

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January 2022

Shear wave elastography and pulsed doppler for breast lesions: Similar diagnostic performance and positively correlated stiffness and blood flow resistance.

Eur J Radiol 2022 Jan 4;147:110149. Epub 2022 Jan 4.

Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China. Electronic address:

Purpose: To compare the diagnostic performance of shear wave elastography (SWE) and pulsed Doppler ultrasound in breast lesions, and to explore whether the quantitative SWE parameters correlated with pulsed Doppler ultrasound parameters.

Materials And Methods: Seventy-nine patients with 79 breast lesions who had undergone conventional ultrasound, pulsed Doppler ultrasound and SWE examination were included. All of them underwent core needle biopsy or surgery within one week. Read More

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January 2022

Cerebrovascular stiffness and flow dynamics in the presence of amyloid and tau biomarkers.

Alzheimers Dement (Amst) 2021 31;13(1):e12253. Epub 2021 Dec 31.

Department of Medical Physics University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.

Introduction: This work investigated the relationship between cerebrovascular disease (CVD) markers and Alzheimer's disease (AD) biomarkers of amyloid beta deposition, and neurofibrillary tau tangles in subjects spanning the AD clinical spectrum.

Methods: A total of 136 subjects participated in this study. Four groups were established based on AD biomarker positivity from positron emission tomography (amyloid [A] and tau [T]) and clinical diagnosis (cognitively normal [CN] and impaired [IM]). Read More

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December 2021

Center-To-Periphery Arterial Stiffness Gradient Is Attenuated and/or Reversed in Pregnancy-Associated Hypertension.

Front Cardiovasc Med 2021 24;8:766723. Epub 2021 Dec 24.

Department of Physiology, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), School of Medicine, Republic University, Montevideo, Uruguay.

Non-pregnant (NP) women have a progressive increase in arterial stiffness from central-to-peripheral arteries ["stiffness gradient" (SG)], which is of physiologic importance since excessive pulsatility is filtered by the creation of wave reflections. If the aorta gets stiff with minimal or no change in the periphery, the SG is dissipated transmitting pressure disturbances to the microcirculation. It remains unknown the status of the SG in both women with healthy pregnancies (HP) and complicated by pregnancy-associated hypertension (PAH). Read More

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December 2021

Morphologic Alterations Precede Functional Hepatic Impairment as Determined by C-Methacetin Liver Function Breath Test in Adult Fontan Patients.

Front Cardiovasc Med 2021 23;8:764009. Epub 2021 Dec 23.

Department of Congenital Heart Disease/Pediatric Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany.

Fontan-associated liver disease (FALD) is the most common end-organ dysfunction affecting up to 70-80% of the Fontan population. The clinical significance of FALD is incompletely understood and no unambiguous correlation between hepatic function and FALD severity has been established. In this study, we sought to evaluate maximal liver function capacity with liver maximum function capacity test (LiMAx®) in adult Fontan patients. Read More

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December 2021

The Relationship Between Arterial Stiffness and Resistance Training.

Cureus 2021 Dec 6;13(12):e20213. Epub 2021 Dec 6.

Psychiatry, Mercy General Hospital, Sacramento, USA.

Exercise is a critical factor that impacts arterial stiffness. In this narrative review, we noted multiple findings that could not be reconciled with one another. Some studies indicated that arterial stiffness increases after a regimen of resistance training. Read More

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December 2021