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The comparison of sexual function in women with or without experience of female genital circumcision: A case-control study in a Kurdish region of Iran.

Health Care Women Int 2021 Apr 2:1-13. Epub 2021 Apr 2.

Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Studies on the sexual consequences of female genital circumcision are controversial. In this article, we intend to compare the sexual function in women with or without experience of circumcision in the Kurdish region of Mahabad in Iran. In this case-control study 550 women completed the demographic and Female Sexual Function Index (FSFI) questionnaires. Read More

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Construction of circRNA-miRNA-mRNA Network for Exploring Underlying Mechanisms of Lubrication Disorder.

Front Cell Dev Biol 2021 11;9:580834. Epub 2021 Mar 11.

Women's Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital), Nanjing, China.

Lubrication disorder is a common health issue that manifests as insufficient sexual arousal at the beginning of sex. It often causes physical and psychological distress. However, there are few studies on lubrication disorder, and the complexity of circular RNA (circRNA) and the related competing endogenous RNA (ceRNA) network in lubrication disorder is still poorly known. Read More

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A prospective controlled study of sexual function and sexually related personal distress up to 12 months after premenopausal risk-reducing bilateral salpingo-oophorectomy.

Menopause 2021 Mar 15. Epub 2021 Mar 15.

School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia Gynaecological Oncology Service, Chris O'Brien Lifehouse, Sydney, Australia Department of Obstetrics and Gynaecology, University of Melbourne and The Royal Women's Hospital, Melbourne, Australia Gynae-oncology and Dysplasia Unit, The Royal Women's Hospital, Melbourne, Australia Basser Center for BRCA, University of Pennsylvania, Philadelphia, PA Prince of Wales Clinical School, University of New South Wales, Sydney, Australia Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, Australia Gynaecology Research Centre, The Royal Women's Hospital, Melbourne, Australia.

Objective: Premenopausal risk-reducing bilateral salpingo-oophorectomy (RRBSO) may impair sexual function, but the nature and degree of impairment and impact of estrogen therapy on sexual function and sexually related personal distress after RRBSO are uncertain.

Methods: Prospective observational study of 73 premenopausal women at elevated risk of ovarian cancer planning RRBSO and 68 premenopausal controls at population risk of ovarian cancer. Participants completed the Female Sexual Function Index and the Female Sexual Distress Scale-Revised. Read More

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Is sexual dysfunction associated with periodontal status in perimenopausal women?: A pilot study.

Oral Dis 2021 Mar 4. Epub 2021 Mar 4.

Department of Urology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.

Objective: The current study aimed to investigate the possible relationship between periodontal status and sexual dysfunction in perimenopausal women.

Materials And Methods: This study was conducted on 106 participants. After the evaluation of the sexual functioning of participants with the Female Sexual Function Index (FSFI), their periodontal status and decayed-missing-filled teeth (DMFT) were assessed using appropriate indexes and obtained results were recorded for comparisons. Read More

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Assessing sexual function in middle-aged sexually active Spanish women: a community-based study focusing on the intimate partner.

Menopause 2021 Mar 1. Epub 2021 Mar 1.

Doctoral Program in Health Sciences at the University of Murcia, Murcia, Spain Department of Nursing, University of Murcia, Murcia, Spain.

Objective: This study evaluated sexual function, the influence of the relationship with the intimate partner, and the factors related to sexual function in middle-aged Spanish women.

Methods: The methodology entailed a cross-sectional study of 187 sexually active women aged 40-59 years. The participants were randomly recruited from primary public health care. Read More

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Sexual Function of Men and Women With Spina Bifida: A Scoping Literature Review.

Sex Med Rev 2021 Feb 16. Epub 2021 Feb 16.

Department of Urology, University of Michigan, Ann Arbor, MI.

Introduction: As most adults with spina bifida are either sexually active or interested in becoming sexually active, providers should understand how spina bifida impacts sexual function and options for treatment.

Objectives: The objective of this study is to summarize the current literature describing how features of spina bifida impact sexual function in men and women, effective available treatment options for sexual dysfunction, and to identify research gaps.

Methods: Searches were conducted in PubMed, CINAHL Complete, PsychInfo, Cochrane Central, Scopus, and Web of Science Core Collection databases using keywords related to spina bifida and sexual function. Read More

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February 2021

The impact of neurogenic bladder bowel dysfunction in the sexuality of female spina bifida patients.

J Pediatr Urol 2021 Jan 20. Epub 2021 Jan 20.

Postgraduate Program in Health Sciences: Gynecology and Obstetrics, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil; Urology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Introduction: The sexual life of Spina Bifida (SB) women may be affected by their physical impairments. Data has consistently associated symptoms such as urinary and fecal incontinence with negative effects on social and intimate life.

Objective: To analyze the female spina bifida patient sexual life and assess which factors - including bladder bowel dysfunction and bladder augmentation - influenced in the sexual function of patients in a multi-center cross-sectional study. Read More

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January 2021

Patient-reported sexual function of breast cancer survivors with genitourinary syndrome of menopause after fractional CO2 laser therapy.

Menopause 2021 Feb 1. Epub 2021 Feb 1.

The Ohio State University Medical Center, Columbus, OH Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH Mayo Clinic, Jacksonville, FL Mayo Clinic, Rochester, MN.

Objective: The objective of this pilot study was to evaluate the change in sexual function following treatment with fractional CO2 laser therapy in breast cancer (BC) survivors with genitourinary syndrome of menopause (GSM).

Methods: A single-arm feasibility study of BC survivors with symptoms of GSM, including dyspareunia and/or vaginal dryness, was conducted. Participants who received three treatments with fractional CO2 laser and 4-week follow-up were contacted for patient-reported outcomes and adverse events at 12 months. Read More

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February 2021

Differences in and Correlates of Sexual Function in Infertile Women with and without Polycystic Ovary Syndrome.

Int J Fertil Steril 2021 Jan 19;15(1):65-72. Epub 2021 Jan 19.

Health Psychology and Behavior Medicine Research Group, Student Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: The aim of this study was to examine sexual function and its correlates among infertile women with polycystic ovary syndrome (PCOS) in comparison with their non-PCOS counterparts.

Materials And Methods: In this case-control study, 209 infertile women (116 PCOS and 93 non-PCOS) from Tehran, Iran, were evaluated in February and March 2018. Female sexual function index (FSFI), hormonal status, and documented reports of hyperandrogenic manifestations of the patients were investigated. Read More

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January 2021

Effect of Sexual Esteem and Sexual Communication on the Relationship Between Body Image and Sexual Function in Chinese Heterosexual Women.

Authors:
Ting Wu Yong Zheng

J Sex Med 2021 Mar 22;18(3):474-486. Epub 2021 Jan 22.

Key Laboratory of Cognition and Personality (Ministry of Education), Southwest University, Chongqing, China. Electronic address:

Background: Sexual self-esteem and communication on sexual issues with a partner contribute greatly to an individual's quality of sex life; however, their effects on the relationship between body image and sexual function are underexplored.

Aim: To test a serial mediating pathway of sexual self-esteem and sexual communication underlying the relationship between body image and sexual function.

Methods: A total of 510 women aged 18-53 years (mean = 28, SD = 5. Read More

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What happens to female sexual function during pregnancy?

Eur J Obstet Gynecol Reprod Biol 2021 Mar 15;258:265-268. Epub 2021 Jan 15.

Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UY, United Kingdom.

Introduction: Female sexual function remains an under-investigated and neglected topic in medical research. Studies have found a strong association between female sexual dysfunction (FSD) and decreased physical, emotional and overall life satisfaction [1]. Although FSD and the impact it has on quality of life is becoming increasingly recognised, the effect of pregnancy on FSD is relatively under-researched. Read More

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Vulvovaginal atrophy of menopause and its impact on sexual function in an Italian clinical cohort of post-menopausal women.

J Obstet Gynaecol 2021 Feb 12;41(2):290-297. Epub 2021 Jan 12.

University of Rome "Sapienza", Department of Gynaecological-Obstetric Sciences and Urological Sciences, Umberto I Hospital, Rome, Italy.

The aim of current study was to estimate the impact of vulvovaginal atrophy (VVA) on sexual function in a clinical population of Italian postmenopausal women. Women aged 45-75 years with at least one VVA symptom completed three questionnaires: Day-to-Day Impact of Vaginal Aging (DIVA), Female Sexual Function Index (FSFI) and Female Sexual Distress Scale revised (FSDS-R). A gynaecological examination was performed for VVA confirmation. Read More

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February 2021

Assessment of premature menopause on the sexual function and quality of life in women.

Gynecol Endocrinol 2021 Apr 12;37(4):307-311. Epub 2021 Jan 12.

Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran.

Introduction: Premature Ovarian Insufficiency (POI) is characterized by ending menstruation in women under 40 years of age. It has a significant effect on women's sexuality and mental health and quality of life. This study aimed to evaluate the sexual function and quality of life of premature menopausal women. Read More

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Does the sexual function of the spouses change after the TOT procedure?

Arch Gynecol Obstet 2021 Jan 2. Epub 2021 Jan 2.

Department of Urology, Medicalpark Hospital, Antalya, Turkey.

Aim: This prospective study aimed to evaluate sexual function in women who underwent transobturator tape (TOT) sling surgery and their male sexual partners compared to before the procedure.

Materials And Methods: The study included a total of 202 women with stress urinary incontinence who underwent the TOT procedure between April 2018 and February 2020, and their partners. All of the women completed the Incontinence Impact Questionnaire (IIQ-7), Urogenital Distress Inventory (UDI-6), and Female Sexual Function Index (FSFI) questionnaire while their partners completed the International Index of Erectile Function (IIEF-5) questionnaire before and 6 months after the procedure. Read More

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January 2021

"Mesh free" autologous transobturator mid urethral sling placement for predominant stress urinary incontinence: A pilot study.

Neurourol Urodyn 2021 02 21;40(2):659-665. Epub 2020 Dec 21.

Department of Urology and Renal transplant, VM Medical College and Safdarjang Hospital, New Delhi, India.

Aims: To assess the efficacy and safety of autologous mid-urethral sling (MUS) in women with predominant stress urinary incontinence (SUI).

Materials And Methods: This prospective cohort study included adult women with predominant SUI seen in our urology clinic between January 2018 and March 2019. Patients with: negative cough stress test, history of prior incontinence surgery, urogenital malignancy, pelvic radiation, neurological disease, body mass index more than 40 kg/m , the presence of more than Stage I pelvic organ prolapse, active urinary tract infection, maximum flow rate less than 15 ml/sec, postvoid residual urine more than 100 ml, abdominal leak point pressure less than 60 cm of H O, and pregnant women were excluded. Read More

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February 2021

The prevalence of sexual dysfunction among postpartum women on the East Coast of Malaysia.

J Taibah Univ Med Sci 2020 Dec 22;15(6):515-521. Epub 2020 Sep 22.

Department of Family Medicine, School of Medicine, Universiti Sains Malaysia, Kubang Kerian, Malaysia.

Objective: Sexual health is a key component of the overall health and quality of life of both men and women. Sexual dysfunction is a common condition, but it lacks professional recognition. This study aims to determine the prevalence and types of sexual dysfunctions among postpartum women in primary care clinics and their associated factors in a Malaysian cohort. Read More

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December 2020

Evaluation of the effect of carrot seed (Daucus Carota) in women of fertile age with hypoactive sexual desire disorder: A randomized double-blind clinical trial.

Complement Ther Med 2020 Nov 29;54:102543. Epub 2020 Aug 29.

Research Institute for Islamic and Complementary Medicine, School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Hypoactive Sexual Desire Disorder (HSDD) is a common sexual problem of women which has negative impacts on their health and quality of life. Given the side effects of pharmacologic interventions, it would be beneficial to patients trying to find new options based on herbal medicine.

Objectives: To evaluate efficacy of carrot seed on sexual dysfunction of women with HSDD compared with placebo. Read More

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November 2020

The relationship between gender role and attitude toward menstruation with female sexual function: A cross-sectional study.

Int J Reprod Biomed 2020 Oct 13;18(10):847-854. Epub 2020 Oct 13.

Department of Midwifery, School of Nursing and Midwifery, Neyshabur University of Medical Sciences, Neyshabur, Iran.

Background: Although female sexual function can be affected by many psychological, interpersonal, and sociocultural factors, limited studies have focused on the relationships between this construct with some concepts such as women's attitudes toward menstruation and perception from their gender role.

Objective: To investigate the association between gender roles and attitude toward menstruation with sexual function among Iranian reproductive women.

Materials And Methods: An observational cross-sectional study was carried out on a group of 164 Iranian women referred to the health centers of Torbat Heydariyeh, between August and December 2018. Read More

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October 2020

Risk factors for sexual dysfunction in Romanian women with type 1 diabetes mellitus and chronic autoimmune thyroiditis: a comparative cross-sectional study.

Diabetol Metab Syndr 2020 27;12:94. Epub 2020 Oct 27.

Second Department of Internal Medicine - Diabetes, Nutrition and Metabolic Diseases, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.

Background: Female sexual dysfunction (FSD) is one of the chronic complications of diabetes as is male sexual dysfunction, but the former is less studied. Therefore, the aim of this study was to assess of the prevalence and risk factors associated with FSD in Romanian women with type 1 diabetes mellitus (T1DM) and chronic autoimmune thyroiditis (CAT).

Methods: The study sample included 104 Romanian women with both T1DM and CAT, and 101 Romanian matched controls with only T1DM. Read More

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October 2020

The Association Between Infant Feeding Methods and Female Sexual Dysfunctions.

Breastfeed Med 2021 Jan 21;16(1):93-99. Epub 2020 Oct 21.

Department of Family Care Methodology, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary.

Although postpartum sexual problems are common, the impact of the infant feeding method on sexual life is still unclear. The aim of this study was to investigate the effects of different infant feeding methods and other influencing factors on female sexual life 3 months postpartum. Three hundred women from three obstetrical institutes were enrolled in this cross-sectional study. Read More

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January 2021

Female Sexual Function and Its Association with the Severity of Menopause-Related Symptoms.

Int J Environ Res Public Health 2020 10 3;17(19). Epub 2020 Oct 3.

Department of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.

The aim of this study was to examine female sexual functioning and its association with the impact of the symptoms of menopause among Spanish postmenopausal women. A total of 182 postmenopausal women (65.59 ± 7. Read More

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October 2020

Sexual Dysfunction and Associated Anxiety and Depression in Female Hemodialysis Patients: A Cross-Sectional Study at Karachi Institute of Kidney Diseases.

Cureus 2020 Aug 31;12(8):e10148. Epub 2020 Aug 31.

Medicine, Jinnah Sindh Medical University, Karachi, PAK.

Objectives Hemodialysis patients have to combat certain negative effects such as sexual dysfunction, depression, and anxiety. This study aimed to measure the sexual function and identify the relationship between sexual dysfunction, depression, and anxiety in females undergoing hemodialysis. Methods The descriptive, cross-sectional study was conducted at a dialysis unit in November 2019. Read More

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Association of female genital mutilation and female sexual dysfunction: A systematic review and meta-analysis.

Eur J Obstet Gynecol Reprod Biol 2020 Nov 25;254:236-244. Epub 2020 Sep 25.

Instituto de Investigación e Innovación en Salud Integral, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.

Objective: To meta-analyze possible associations between female genital mutilation (FGM) and female sexual dysfunction, dyspareunia and pelvic pain.

Method: A systematic literature search was performed in PubMed, EMBASE, Scopus, Web of Science, African Index Medicus and Cochrane Library. The PICO protocol included Population: Studies evaluating girls or women; Intervention/Exposure: participants with FGM; Comparison: participants without FGM; Outcomes: female sexual function, dyspareunia or pelvic pain using validated tests. Read More

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November 2020

The Impact of COVID-19 on Female Sexual Health.

Int J Environ Res Public Health 2020 09 30;17(19). Epub 2020 Sep 30.

Chair and Department of Gynecology, Obstetrics and Oncological Gynecology, Medical University of Silesia in Katowice, Markiefki 87, 40-211 Katowice, Poland.

Introduction: Coronavirus disease (COVID-19), announced as a pandemic by the World Health Organization, recently has dominated people's lifestyle. The impact of COVID-19 seems to be relevant to the sexual health as well.

Methods: This prospective study was conducted on two occasions involving 764 female patients between March and April 2020-before and during the time of social quarantine. Read More

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September 2020

Sexual dysfunction and its determinants in women with rheumatoid arthritis.

Z Rheumatol 2020 Sep 29. Epub 2020 Sep 29.

Rheumatology Department, Mongi Slim Hospital, La Marsa, Tunisia.

Objectives: To evaluate sexual function in Tunisian women with rheumatoid arthritis (RA) and to examine factors that are predictors of female sexual dysfunction including sociocultural factors, disease activity, and psychological status.

Methods: We conducted a cross-sectional study including 71 women with a confirmed diagnosis of RA according to the 2010 American College of Rheumatology/European League against Rheumatism (ACR/EULAR) criteria. Clinical and sociodemographic characteristics were collected. Read More

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September 2020

Treatment of women's sexual dysfunction using Apium graveolens L. Fruit (celery seed): A double-blind, randomized, placebo-controlled clinical trial.

J Ethnopharmacol 2021 Jan 22;264:113400. Epub 2020 Sep 22.

Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Ethnopharmacological Relevance: Traditional manuscripts refer to plants such as Apium graveolens L. Fruit (celery seed), which could be used to improve sexual function among women. Since that time, local herbal shops in Iran continue to provide this herb as a natural aphrodisiac product. Read More

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January 2021

Gold Thread Implantation for Female Sexual Dysfunction and Vaginal Laxity: A Preliminary Investigation.

J Menopausal Med 2020 Aug;26(2):130-134

Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.

Objectives: We evaluated the efficacy of gold thread implantation (GTI) in the vulva and vagina to improve female sexual dysfunction (FSD) and vaginal laxity.

Methods: A retrospective chart review was conducted on 46 women who underwent GTI between 2017 and 2018 at our institution. Physicians interviewed patients using questionnaires at baseline and 1-3 months post-treatment. Read More

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The effect of endometriosis on sexual function as assessed with the Female Sexual Function Index: systematic review and meta-analysis.

Gynecol Endocrinol 2020 Nov 3;36(11):1015-1023. Epub 2020 Sep 3.

Instituto de Investigación e Innovación en Salud Integral, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.

Aim: To systematically compare sexual function between non-treated women with and without endometriosis.

Methods: A systematic review was performed on PubMed/Medline, Scopus, EMBASE, Web of Science and Cochrane Library databases searching studies that analyzed sexual function (assessed with the 19-item Female Sexual Function Index [FSFI]), and dyspareunia, chronic pelvic pain and dysmenorrhea (assessed with a visual analogue scale [VAS]) in women with and with endometriosis.

Results: In 4 studies, non-treated women with endometriosis presented a higher risk of female sexual dysfunction (mean total FSFI score ≤ 26. Read More

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November 2020

Association Between Overt Hyperthyroidism and Risk of Sexual Dysfunction in Both Sexes: A Systematic Review and Meta-Analysis.

J Sex Med 2020 11 13;17(11):2198-2207. Epub 2020 Aug 13.

Department of Urology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China. Electronic address:

Background: Numerous studies have shown the detrimental effects of overt hyperthyroidism on sexual functioning but a quantitative result has not yet been synthesized.

Aim: To conduct a systematic review and meta-analysis that quantifies the association between overt hyperthyroidism and the risk of sexual dysfunction (SD).

Methods: A meta-analysis of studies in the literature published prior to February 1, 2020, from 4 electronic databases (MEDLINE, Embase, Cochrane Library databases, and PsychINFO) was conducted. Read More

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November 2020